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CH528479A - Verfahren zur Herstellung von Alkanolaminderivaten - Google Patents

Verfahren zur Herstellung von Alkanolaminderivaten

Info

Publication number
CH528479A
CH528479A CH234672A CH234672A CH528479A CH 528479 A CH528479 A CH 528479A CH 234672 A CH234672 A CH 234672A CH 234672 A CH234672 A CH 234672A CH 528479 A CH528479 A CH 528479A
Authority
CH
Switzerland
Prior art keywords
preparation
alkanolamine derivatives
alkanolamine
derivatives
Prior art date
Application number
CH234672A
Other languages
English (en)
Inventor
Frederick Crowther Albert
Harold Smith Leslie
Miller Wood Thomas
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Ltd filed Critical Ici Ltd
Priority claimed from GB3934465A external-priority patent/GB1123258A/en
Publication of CH528479A publication Critical patent/CH528479A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/402,5-Pyrrolidine-diones
    • C07D207/4042,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • C07D207/408Radicals containing only hydrogen and carbon atoms attached to ring carbon atoms
    • C07D207/412Acyclic radicals containing more than six carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58Preparation of carboxylic acid halides
    • C07C51/60Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/36Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CH234672A 1962-12-11 1963-12-10 Verfahren zur Herstellung von Alkanolaminderivaten CH528479A (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB46740/62A GB1069341A (en) 1962-12-11 1962-12-11 Pharmaceutical compositions containing alkanolamine derivatives
GB2871763 1963-07-19
GB4674063 1963-11-13
GB3934465A GB1123258A (en) 1965-09-15 1965-09-15 Alkanolamine derivatives

Publications (1)

Publication Number Publication Date
CH528479A true CH528479A (de) 1972-09-30

Family

ID=27448750

Family Applications (3)

Application Number Title Priority Date Filing Date
CH1509363A CH515212A (de) 1962-12-11 1963-12-10 Verfahren zur Herstellung von Alkanolaminderivaten
CH234672A CH528479A (de) 1962-12-11 1963-12-10 Verfahren zur Herstellung von Alkanolaminderivaten
CH507167A CH461532A (de) 1962-12-11 1963-12-10 Verfahren zur Herstellung von Alkanolaminderivaten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH1509363A CH515212A (de) 1962-12-11 1963-12-10 Verfahren zur Herstellung von Alkanolaminderivaten

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH507167A CH461532A (de) 1962-12-11 1963-12-10 Verfahren zur Herstellung von Alkanolaminderivaten

Country Status (9)

Country Link
US (1) US3501769A (de)
BE (2) BE641133A (de)
CH (3) CH515212A (de)
DE (3) DE1792711C3 (de)
DK (1) DK121866B (de)
FI (1) FI42094B (de)
GB (1) GB1069341A (de)
NL (2) NL6612958A (de)
SE (1) SE323085B (de)

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US3668206A (en) * 1968-10-16 1972-06-06 Venkatachala Lakshmi Narayanan Heterocyclic amine derivatives of 5,8-dihydronaphthyloxy propanols
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FR2119843B1 (de) * 1970-12-28 1974-03-22 Laroche Navarro Labo
FR2119844B1 (de) * 1970-12-28 1974-03-22 Laroche Navarro Labo
GB1395156A (en) * 1971-07-28 1975-05-21 Ici Ltd Aldehyde derivatives
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DE2962112D1 (en) * 1978-02-08 1982-03-25 Ici Plc Alkanolamine derivatives, process for their preparation and pharmaceutical compositions containing them
DE2805404A1 (de) * 1978-02-09 1979-08-16 Merck Patent Gmbh 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung
US4341718A (en) * 1978-07-03 1982-07-27 American Home Products Corporation α-[(Alkylamino)-methyl]-β-aryloxy-benzeneethanols exhibiting antiarrhythmic activity
DE2839475A1 (de) * 1978-09-11 1980-03-20 Dolorgiet Arzneimittelfabrik Isopropylamin-verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
IT1113029B (it) * 1979-03-01 1986-01-20 Simes Processo per la separazione dei due isomeri ottici del moprololo e composizioni farmaceutiche dell'antipodo levogiro
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DE3151201A1 (de) * 1981-12-23 1983-07-28 Beiersdorf Ag, 2000 Hamburg Substituierte phenoxyalkanolamine und phenoxyalkanol-cycloalkylamine, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische zubereitungen und zwischenprodukte
DE3237400A1 (de) * 1982-10-08 1984-04-12 Bayer Ag, 5090 Leverkusen Substituierte 1-hydroxyethyl-triazolyl-derivate
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NZ211815A (en) * 1984-05-15 1988-11-29 Warner Lambert Co Preparation of 1-((3,4-dimethoxyphenethyl)amino)-3- (3-tolyloxy)-2-propanol
JPS61210063A (ja) * 1985-03-14 1986-09-18 Mitsubishi Chem Ind Ltd アリ−ルスルホン類
DE3544172A1 (de) * 1985-12-13 1987-06-19 Lentia Gmbh Neue kristalline salze von aryloxy-propanolaminen, verfahren zu ihrer herstellung und ihre verwendung
ES2005525T3 (es) * 1987-03-26 1992-10-01 Helopharm W. Petrik Gmbh & Co.Kg. Procedimiento para la fabricacion de 5-hidroxi-diprafenona y sus sales con acidos.
TW275614B (de) * 1993-02-15 1996-05-11 Senju Pharma Co
US5488064A (en) * 1994-05-02 1996-01-30 Bristol-Myers Squibb Company Benzo 1,3 dioxole derivatives
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US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
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JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのcetp阻害剤としてのn−((3−ベンジル)−2,2−(ビス−フェニル)−プロパン−1−アミン誘導体
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GB622297A (en) * 1946-12-06 1949-04-29 British Drug Houses Ltd Improvements in or relating to the preparation of basic ethers
US3033640A (en) * 1954-06-16 1962-05-08 Saul & Co Incorporation of an organic basic compound into cellulose acetate materials
DE1220440B (de) * 1962-02-14 1966-07-07 Sanol Arznei Schwarz Gmbh Verfahren zur Herstellung von Derivaten des 1-(o-Bromphenoxy)-2-hydroxy-3-amino-propans und deren Saeureadditionssalzen
US3275629A (en) * 1963-03-20 1966-09-27 Monsanto Co Substituted aryloxyalkylene amines

Also Published As

Publication number Publication date
DE1493848B2 (de) 1977-11-17
DE1493848A1 (de) 1972-03-30
NL301580A (de)
DE1792711A1 (de) 1972-08-10
FI42094B (de) 1970-02-02
BE641133A (de) 1964-06-11
CH515212A (de) 1971-11-15
US3501769A (en) 1970-03-17
NL6612958A (de) 1967-03-16
DE1792711C3 (de) 1979-02-08
GB1069341A (en) 1967-05-17
SE323085B (de) 1970-04-27
DK121866B (da) 1971-12-13
DE1543701A1 (de) 1972-08-10
DE1792711B2 (de) 1978-06-22
DE1493848C3 (de) 1978-07-06
CH461532A (de) 1968-08-31
BE686949A (de) 1967-03-15

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