CA2790802C - Oligoribonucleotides immunostimulateurs - Google Patents
Oligoribonucleotides immunostimulateurs Download PDFInfo
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- CA2790802C CA2790802C CA2790802A CA2790802A CA2790802C CA 2790802 C CA2790802 C CA 2790802C CA 2790802 A CA2790802 A CA 2790802A CA 2790802 A CA2790802 A CA 2790802A CA 2790802 C CA2790802 C CA 2790802C
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Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Abstract
Linvention concerne des compositions immunostimulatrices et lutilisation de ces composés dans la préparation de médicaments utilisés dans le traitement de maladies ainsi que dans des utilisations in vitro. Les compositions de linvention comprennent, en particulier, des oligoribonucléotides immunostimulateurs incorporant un motif séquentiel immunostimulateur dépendant de la séquence. Des modifications spécifiques associées à des liaisons phosphate, des analogues des nucléotides, des composés daddition et des combinaisons de ceux-ci sont décrites. Les compositions de linvention, pouvant éventuellement contenir un antigène, peuvent être utilisées seules ou conjointement à dautres traitements pour stimuler ou améliorer une réponse immune. Linvention concerne également des compositions et des méthodes utilisées dans le traitement dun sujet souffrant dune infection, dun cancer, dune allergie, dasthme, dun remodelage des voies aériennes ou dune immunodéficience. Les oligoribonucléotides immunostimulateurs de linvention stimuleraient le récepteur 8 de type Toll (TLR8). Spécifiquement, linvention a trait à un oligoribonucléotide comprenant la séquence telle quétablie dans le numéro ID SEQ 21.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73952905P | 2005-11-25 | 2005-11-25 | |
| US60/739,529 | 2005-11-25 | ||
| US77898906P | 2006-03-03 | 2006-03-03 | |
| US60/778,989 | 2006-03-03 | ||
| CA2630738A CA2630738C (fr) | 2005-11-25 | 2006-11-22 | Oligoribonucleotides immunostimulateurs |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2630738A Division CA2630738C (fr) | 2005-11-25 | 2006-11-22 | Oligoribonucleotides immunostimulateurs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2790802A1 CA2790802A1 (fr) | 2007-05-31 |
| CA2790802C true CA2790802C (fr) | 2016-07-12 |
Family
ID=40206401
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2790802A Active CA2790802C (fr) | 2005-11-25 | 2006-11-22 | Oligoribonucleotides immunostimulateurs |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN101331229B (fr) |
| CA (1) | CA2790802C (fr) |
| ZA (1) | ZA200804303B (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021064614A1 (fr) * | 2019-09-30 | 2021-04-08 | Janssen Biopharma, Inc. | Agonistes du récepteur de type toll 7 et/ou toll 8 et utilisations associées |
| CN115137736A (zh) * | 2022-02-17 | 2022-10-04 | 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） | 一种抗非洲猪瘟病毒的药物及其筛选方法 |
-
2006
- 2006-11-22 CN CN2006800440306A patent/CN101331229B/zh active Active
- 2006-11-22 CA CA2790802A patent/CA2790802C/fr active Active
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2008
- 2008-05-19 ZA ZA200804303A patent/ZA200804303B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2790802A1 (fr) | 2007-05-31 |
| CN101331229A (zh) | 2008-12-24 |
| CN101331229B (zh) | 2012-08-29 |
| ZA200804303B (en) | 2009-03-25 |
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| CA2630738C (fr) | Oligoribonucleotides immunostimulateurs | |
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| US20060241076A1 (en) | Modified oligoribonucleotide analogs with enhanced immunostimulatory activity | |
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| EEER | Examination request |