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CA2597757C - Cellules endotheliales vasculaires/lymphatiques - Google Patents

Cellules endotheliales vasculaires/lymphatiques Download PDF

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Publication number
CA2597757C
CA2597757C CA2597757A CA2597757A CA2597757C CA 2597757 C CA2597757 C CA 2597757C CA 2597757 A CA2597757 A CA 2597757A CA 2597757 A CA2597757 A CA 2597757A CA 2597757 C CA2597757 C CA 2597757C
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CA
Canada
Prior art keywords
cells
cell
embryonic
combination
seq
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Active
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CA2597757A
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English (en)
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CA2597757A1 (fr
Inventor
Felipe Prosper
Catherine M. Verfaillie
Xabier Lopez-Aranguren
Carlos Clavel Claver
Aernout Luttun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Proyecto de Biomedicina CIMA SL
University of Minnesota System
Original Assignee
Proyecto de Biomedicina CIMA SL
University of Minnesota System
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Publication of CA2597757A1 publication Critical patent/CA2597757A1/fr
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • C12N5/0691—Vascular smooth muscle cells; 3D culture thereof, e.g. models of blood vessels
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/165—Vascular endothelial growth factor [VEGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/42—Notch; Delta; Jagged; Serrate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/03—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Vascular Medicine (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des procédés de culture et d'utilisation de cellules endothéliales vasculaires, notamment des cellules endothéliales lymphatiques, veineuses et artérielles.
CA2597757A 2005-02-10 2006-02-10 Cellules endotheliales vasculaires/lymphatiques Active CA2597757C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65201505P 2005-02-10 2005-02-10
US60/652,015 2005-02-10
PCT/US2006/004749 WO2006086639A1 (fr) 2005-02-10 2006-02-10 Cellules endotheliales vasculaires/lymphatiques

Publications (2)

Publication Number Publication Date
CA2597757A1 CA2597757A1 (fr) 2006-08-17
CA2597757C true CA2597757C (fr) 2016-06-28

Family

ID=36407963

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2597757A Active CA2597757C (fr) 2005-02-10 2006-02-10 Cellules endotheliales vasculaires/lymphatiques

Country Status (5)

Country Link
US (1) US20090104159A1 (fr)
EP (2) EP1859028B1 (fr)
CA (1) CA2597757C (fr)
HK (1) HK1109172A1 (fr)
WO (1) WO2006086639A1 (fr)

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US7585670B2 (en) 2001-12-07 2009-09-08 Cytori Therapeutics, Inc. Automated methods for isolating and using clinically safe adipose derived regenerative cells
WO2003053346A2 (fr) 2001-12-07 2003-07-03 Macropore Biosurgery, Inc. Systemes et methodes de traitement de patients ayant des cellules aspirees par liposuccion traitees
US9597395B2 (en) 2001-12-07 2017-03-21 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
US7771716B2 (en) 2001-12-07 2010-08-10 Cytori Therapeutics, Inc. Methods of using regenerative cells in the treatment of musculoskeletal disorders
US20050095228A1 (en) 2001-12-07 2005-05-05 Fraser John K. Methods of using regenerative cells in the treatment of peripheral vascular disease and related disorders
MX2008012178A (es) 2006-03-24 2009-01-23 Childrens Medical Center Metodo para modular el crecimiento de celulas madre hematopoyeticas.
WO2007149548A2 (fr) * 2006-06-22 2007-12-27 Medistem Laboratories, Inc. Traitement d'un dysfonctionnement érectile par une thérapie à base de cellules souches
EP3824885A1 (fr) 2006-10-20 2021-05-26 Children's Medical Center Corporation Procédé pour améliorer la régénération tissulaire
US9005964B2 (en) 2006-11-24 2015-04-14 Regents Of The University Of Minnesota Endodermal progenitor cells
WO2009092092A1 (fr) 2008-01-18 2009-07-23 Regents Of The University Of Minnesota Agrégats de cellules souches et procédés de préparation et d'utilisation
WO2010021993A1 (fr) * 2008-08-19 2010-02-25 Cytori Therapeutics, Inc. Procédés d'utilisation de cellules issues du tissu adipeux dans le traitement du système lymphatique et d'une maladie maligne
US9056085B2 (en) 2009-02-03 2015-06-16 Children's Medical Center Corporation Methods for enhancing hematopoietic stem/progenitor cell engraftment
US9051548B2 (en) 2009-02-03 2015-06-09 Children's Medical Center Corporation Methods for enhancing hematopoietic stem/progenitor cell engraftment
EP2424463B1 (fr) * 2009-05-01 2016-12-28 Bimini Technologies LLC Systèmes, procédés et compositions permettant d'optimiser des greffons enrichis en tissus et cellules
FR3003870B1 (fr) * 2010-01-12 2015-10-02 Centre Nat Rech Scient Lignees de cellules souches humaines et murines: modeles de precurseurs de cellules endotheliales
CA3128483A1 (fr) 2010-05-12 2011-11-17 Abt Holding Company Modulation des splenocytes en therapie cellulaire
US20120295347A1 (en) * 2011-05-20 2012-11-22 Steven Kessler Methods and Compositions for Producing Endothelial Progenitor Cells from Pluripotent Stem Cells
WO2013103423A2 (fr) 2011-10-11 2013-07-11 Fibralign Corporation Greffe destinée à la régénération vasculaire et lymphatique et procédés de guidage d'ensemble de cellules endothéliales
WO2013082241A2 (fr) 2011-12-02 2013-06-06 Fate Therapeutics, Inc. Méthodes améliorées permettant de traiter l'ischémie
JP6220791B2 (ja) 2011-12-02 2017-10-25 フェイト セラピューティクス，インコーポレイテッド 増強された幹細胞組成物
ES2731529T3 (es) 2012-12-18 2019-11-15 Biocant Associacao De Transferencia De Tecnologia Población celular diferenciada de células endoteliales derivadas de células madre pluripotentes humanas, composición, sistema, kit y usos de la misma
US10851412B2 (en) 2013-03-15 2020-12-01 Fate Therapeutics, Inc. Cell potency assay for therapeutic potential
ES2827250T3 (es) 2013-04-12 2021-05-20 Houston Methodist Hospital Mejora de órganos para trasplante
CA2914615C (fr) 2013-06-05 2023-10-17 Biotime, Inc. Compositions et procedes pour la regeneration de tissus induite chez des especes mammaliennes
US10206941B2 (en) 2013-07-09 2019-02-19 President And Fellows Of Harvard College Venule endothelial cell genes and uses thereof
WO2015006501A2 (fr) 2013-07-09 2015-01-15 President And Fellows Of Harvard College Marqueurs de surface de cellules endothéliales de microvaisseaux et utilisations de ceux-ci
WO2015054654A1 (fr) * 2013-10-10 2015-04-16 Fibralign Corporation Méthode et dispositif de traitement du lymphœdème
US11078462B2 (en) 2014-02-18 2021-08-03 ReCyte Therapeutics, Inc. Perivascular stromal cells from primate pluripotent stem cells
US10240127B2 (en) 2014-07-03 2019-03-26 ReCyte Therapeutics, Inc. Exosomes from clonal progenitor cells
JP6691921B2 (ja) 2015-02-20 2020-05-13 ウィスコンシン アラムニ リサーチ ファンデーション 動脈内皮細胞集団の生成
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US10767164B2 (en) 2017-03-30 2020-09-08 The Research Foundation For The State University Of New York Microenvironments for self-assembly of islet organoids from stem cells differentiation

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Also Published As

Publication number Publication date
HK1109172A1 (en) 2008-05-30
US20090104159A1 (en) 2009-04-23
EP2428563A1 (fr) 2012-03-14
WO2006086639A1 (fr) 2006-08-17
EP1859028B1 (fr) 2015-12-02
CA2597757A1 (fr) 2006-08-17
EP1859028A1 (fr) 2007-11-28

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