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CA2557549A1 - Systeme et procede d'integration de fluides et de reactifs dans des cartouches autonomes contenant des detecteurs de membrane et de particules - Google Patents

Systeme et procede d'integration de fluides et de reactifs dans des cartouches autonomes contenant des detecteurs de membrane et de particules Download PDF

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Publication number
CA2557549A1
CA2557549A1 CA002557549A CA2557549A CA2557549A1 CA 2557549 A1 CA2557549 A1 CA 2557549A1 CA 002557549 A CA002557549 A CA 002557549A CA 2557549 A CA2557549 A CA 2557549A CA 2557549 A1 CA2557549 A1 CA 2557549A1
Authority
CA
Canada
Prior art keywords
membrane
particle
cartridge
fluid
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002557549A
Other languages
English (en)
Inventor
John T. Mcdevitt
Eric V. Anslyn
Jason B. Shear
Dean P. Neikirk
Nick J. Christodoulides
Karri L. Michael-Ballard
Pierre N. Floriano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Texas System
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/020,442 external-priority patent/US20060257991A1/en
Priority claimed from US11/022,365 external-priority patent/US20060257941A1/en
Application filed by Individual filed Critical Individual
Publication of CA2557549A1 publication Critical patent/CA2557549A1/fr
Abandoned legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0893—Geometry, shape and general structure having a very large number of wells, microfabricated wells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6419—Excitation at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N2021/6417—Spectrofluorimetric devices
    • G01N2021/6421—Measuring at two or more wavelengths
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7786—Fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/02—Mechanical
    • G01N2201/022—Casings
    • G01N2201/0221—Portable; cableless; compact; hand-held

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Fluid Mechanics (AREA)
  • Plasma & Fusion (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA002557549A 2004-02-27 2005-02-28 Systeme et procede d'integration de fluides et de reactifs dans des cartouches autonomes contenant des detecteurs de membrane et de particules Abandoned CA2557549A1 (fr)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US54819004P 2004-02-27 2004-02-27
US54860104P 2004-02-27 2004-02-27
US54861304P 2004-02-27 2004-02-27
US60/548,190 2004-02-27
US60/548,613 2004-02-27
US60/548,601 2004-02-27
US11/020,442 US20060257991A1 (en) 2004-02-27 2004-12-22 Integration of fluids and reagents into self-contained cartridges containing particle-based sensor elements and membrane-based sensor elements
US11/022,365 2004-12-22
US11/022,365 US20060257941A1 (en) 2004-02-27 2004-12-22 Integration of fluids and reagents into self-contained cartridges containing particle and membrane sensor elements
US11/020,442 2004-12-22
PCT/US2005/006349 WO2005083423A2 (fr) 2004-02-27 2005-02-28 Systeme et procede d'integration de fluides et de reactifs dans des cartouches autonomes contenant des detecteurs de membrane et de particules

Publications (1)

Publication Number Publication Date
CA2557549A1 true CA2557549A1 (fr) 2005-09-09

Family

ID=34916570

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002557549A Abandoned CA2557549A1 (fr) 2004-02-27 2005-02-28 Systeme et procede d'integration de fluides et de reactifs dans des cartouches autonomes contenant des detecteurs de membrane et de particules

Country Status (3)

Country Link
EP (1) EP1735618A2 (fr)
CA (1) CA2557549A1 (fr)
WO (1) WO2005083423A2 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009048790A1 (de) * 2009-10-08 2011-04-21 Eads Deutschland Gmbh Biosensorvorrichtung mit Filterüberwachungseinrichtung
DE102019122981A1 (de) * 2019-08-27 2021-03-04 Westfälische Wilhelms-Universität Münster Vorrichtung und Verfahren zum Sortieren von Partikeln mittels Strahlung
CN114113023A (zh) * 2021-12-16 2022-03-01 郑州轻工业大学 基于单核增生李斯特菌来源的氮掺杂碳点的制备方法和应用
CN114308162A (zh) * 2021-12-31 2022-04-12 北京百奥纳芯生物科技有限公司 辅助基因芯片探针与基片结合固定的装置
CN116306385A (zh) * 2023-05-24 2023-06-23 中国石油大学(华东) 一种油藏压裂渗吸增能数值模拟方法、系统、设备及介质

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WO2007002480A2 (fr) * 2005-06-24 2007-01-04 Board Of Regents, The University Of Texas System Systemes et procedes faisant appel a des cartouches autonomes comprenant des systemes de detection et des systemes de distribution de fluides
KR20090027643A (ko) * 2006-05-17 2009-03-17 루미넥스 코포레이션 형광성 표지가 부착된 입자를 분석하기 위해 칩에 기초한 유세포분석기 시스템
US20080245740A1 (en) * 2007-01-29 2008-10-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Fluidic methods
EP2335370B1 (fr) * 2008-06-04 2014-03-19 TissUse GmbH Dispositif d'organe sur puce
WO2010053951A1 (fr) * 2008-11-05 2010-05-14 Nanopoint, Inc. Système microfluidique actif pour culture in vitro
GB0919159D0 (en) 2009-11-02 2009-12-16 Sec Dep For Environment Food A Device and apparatus
EP2607889A4 (fr) * 2010-08-18 2016-11-09 Nanoentek Inc Microscope à fluorescence pour observation d'image à fluorescence multiple, procédé d'observation d'image à fluorescence l'utilisant, et système d'observation d'image à fluorescence multiple
US9671413B2 (en) 2010-11-12 2017-06-06 William Marsh Rice University Prostate cancer point of care diagnostics
US9535068B2 (en) 2010-11-12 2017-01-03 William Marsh Rice University Oral cancer point of care diagnostics
SG194892A1 (en) 2011-05-12 2013-12-30 Univ Rice William M Bio-nano-chips for on-site drug screening
US20140322706A1 (en) 2012-10-24 2014-10-30 Jon Faiz Kayyem Integrated multipelx target analysis
EP2965817B1 (fr) 2012-10-24 2017-09-27 Genmark Diagnostics Inc. Analyse de cibles multiplexes integrées
EP3034171B1 (fr) 2013-03-15 2019-04-24 Genmark Diagnostics Inc. Systèmes, procédés et appareil de manipulation de récipients de fluides déformables
US10060937B2 (en) 2013-06-28 2018-08-28 William Marsh Rice University Integrated instrumentation for the analysis of biofluids at the point-of-care
US9498778B2 (en) 2014-11-11 2016-11-22 Genmark Diagnostics, Inc. Instrument for processing cartridge for performing assays in a closed sample preparation and reaction system
WO2015134945A1 (fr) * 2014-03-07 2015-09-11 Life Technologies Corporation Appareil de séquençage utilisant une électrophorèse capillaire
EP3655160A4 (fr) 2017-07-19 2021-04-07 Evanostics, LLC Cartouches pour analyse de fluide oral et procédés d'utilisation
EP3724636A4 (fr) 2017-12-15 2021-08-18 Evanostics, LLC Lecteur optique pour test d'analyte
EP3821230B1 (fr) * 2018-07-09 2024-03-27 PreSens Precision Sensing GmbH Système d'analyse d'un échantillon de fluide
US12066383B2 (en) 2018-12-18 2024-08-20 Aspida Dx Inc. Optical analyte detection
WO2020231399A1 (fr) * 2019-05-13 2020-11-19 Hewlett-Packard Development Company, L.P. Analyseurs de cellules

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US4935346A (en) * 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
FR2638240B1 (fr) 1988-10-21 1991-10-18 Biocom Sa Platine pour l'analyse rapide et indexee sous microscope de filtres et d'autres supports porteurs d'echantillons multiples et procede d'analyse de ces echantillons utilisant cette platine
WO1992005440A1 (fr) * 1990-09-26 1992-04-02 Akers Research Corporation Analyse de detection amelioree de ligands
US6750031B1 (en) 1996-01-11 2004-06-15 The United States Of America As Represented By The Secretary Of The Navy Displacement assay on a porous membrane
US6048732A (en) * 1996-10-16 2000-04-11 Board Of Regents, The University Of Texas System Receptor and method for citrate determination
US6327410B1 (en) * 1997-03-14 2001-12-04 The Trustees Of Tufts College Target analyte sensors utilizing Microspheres
AU2003228711C1 (en) 2002-04-26 2010-01-07 Board Of Regents, The University Of Texas System Method and system for the detection of cardiac risk factors

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009048790A1 (de) * 2009-10-08 2011-04-21 Eads Deutschland Gmbh Biosensorvorrichtung mit Filterüberwachungseinrichtung
DE102009048790B4 (de) * 2009-10-08 2015-07-02 Airbus Defence and Space GmbH Biosensorvorrichtung mit Filterüberwachungseinrichtung
DE102019122981A1 (de) * 2019-08-27 2021-03-04 Westfälische Wilhelms-Universität Münster Vorrichtung und Verfahren zum Sortieren von Partikeln mittels Strahlung
CN114113023A (zh) * 2021-12-16 2022-03-01 郑州轻工业大学 基于单核增生李斯特菌来源的氮掺杂碳点的制备方法和应用
CN114113023B (zh) * 2021-12-16 2024-04-26 郑州轻工业大学 基于单核增生李斯特菌来源的氮掺杂碳点的制备方法和应用
CN114308162A (zh) * 2021-12-31 2022-04-12 北京百奥纳芯生物科技有限公司 辅助基因芯片探针与基片结合固定的装置
CN114308162B (zh) * 2021-12-31 2023-05-05 北京百奥纳芯生物科技有限公司 辅助基因芯片探针与基片结合固定的装置
CN116306385A (zh) * 2023-05-24 2023-06-23 中国石油大学(华东) 一种油藏压裂渗吸增能数值模拟方法、系统、设备及介质
CN116306385B (zh) * 2023-05-24 2023-07-28 中国石油大学(华东) 一种油藏压裂渗吸增能数值模拟方法、系统、设备及介质

Also Published As

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WO2005083423A3 (fr) 2005-10-20
EP1735618A2 (fr) 2006-12-27
WO2005083423A2 (fr) 2005-09-09

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