CA2557075A1 - Composes inhibiteurs de methylation - Google Patents
Composes inhibiteurs de methylation Download PDFInfo
- Publication number
- CA2557075A1 CA2557075A1 CA002557075A CA2557075A CA2557075A1 CA 2557075 A1 CA2557075 A1 CA 2557075A1 CA 002557075 A CA002557075 A CA 002557075A CA 2557075 A CA2557075 A CA 2557075A CA 2557075 A1 CA2557075 A1 CA 2557075A1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
- C07H19/11—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids containing cyclic phosphate
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54790204P | 2004-02-25 | 2004-02-25 | |
| US60/547,902 | 2004-02-25 | ||
| PCT/US2005/006173 WO2005082144A1 (fr) | 2004-02-25 | 2005-02-25 | Composes inhibiteurs de methylation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2557075A1 true CA2557075A1 (fr) | 2005-09-09 |
Family
ID=34910960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002557075A Abandoned CA2557075A1 (fr) | 2004-02-25 | 2005-02-25 | Composes inhibiteurs de methylation |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1718150A1 (fr) |
| AU (1) | AU2005216971A1 (fr) |
| CA (1) | CA2557075A1 (fr) |
| WO (1) | WO2005082144A1 (fr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8207142B2 (en) | 2001-07-31 | 2012-06-26 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Inhibitor of DNA methylation |
| DE102006059294B4 (de) * | 2006-12-13 | 2011-01-20 | International University Bremen Gmbh | Methylierungsinhibitor für eine eukaryontische Nukleinsäure-Methylierungsreaktion, dessen Verwendung, Inhibierungsverfahren und Bestimmungsverfahren der Inhibierungswirkung |
| US7964580B2 (en) | 2007-03-30 | 2011-06-21 | Pharmasset, Inc. | Nucleoside phosphoramidate prodrugs |
| DE102007022274A1 (de) * | 2007-05-09 | 2008-11-20 | Jacobs University Bremen Ggmbh | Verfahren und Reagenzien zur Untersuchung von Nukleinsäure-Methylierungsreaktionen |
| US8173621B2 (en) * | 2008-06-11 | 2012-05-08 | Gilead Pharmasset Llc | Nucleoside cyclicphosphates |
| SG194404A1 (en) | 2008-12-23 | 2013-11-29 | Gilead Pharmasset Llc | Synthesis of purine nucleosides |
| WO2010123354A2 (fr) * | 2009-04-20 | 2010-10-28 | Erasmus University Medical Center Rotterdam | Méthode de diagnostic du cancer de la vessie |
| TWI576352B (zh) | 2009-05-20 | 2017-04-01 | 基利法瑪席特有限責任公司 | 核苷磷醯胺 |
| US8618076B2 (en) | 2009-05-20 | 2013-12-31 | Gilead Pharmasset Llc | Nucleoside phosphoramidates |
| US8563530B2 (en) | 2010-03-31 | 2013-10-22 | Gilead Pharmassel LLC | Purine nucleoside phosphoramidate |
| PT2609923T (pt) | 2010-03-31 | 2017-08-30 | Gilead Pharmasset Llc | Processo para a cristalização de 2-(((s)- (perfluorofenoxi)(fenoxi)fosforil)amino)propanoato de (s)-isopropilo |
| EP2646453A1 (fr) | 2010-11-30 | 2013-10-09 | Gilead Pharmasset LLC | Composés |
| PE20141056A1 (es) | 2011-09-16 | 2014-09-05 | Gilead Pharmasset Llc | Metodos para el tratamiento de vhc |
| US8889159B2 (en) | 2011-11-29 | 2014-11-18 | Gilead Pharmasset Llc | Compositions and methods for treating hepatitis C virus |
| MX351816B (es) | 2013-01-31 | 2017-10-30 | Gilead Pharmasset Llc | Formulacion de combinacion de dos compuestos antivirales. |
| PT3038601T (pt) | 2013-08-27 | 2020-06-30 | Gilead Pharmasset Llc | Formulação combinada de dois compostos antivirais |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998048843A1 (fr) * | 1997-04-28 | 1998-11-05 | Arsinur Burcoglu | Traitement de l'infection par vih et de ses infections opportunistes |
| US6613753B2 (en) * | 2001-02-21 | 2003-09-02 | Supergen, Inc. | Restore cancer-suppressing functions to neoplastic cells through DNA hypomethylation |
| US6905669B2 (en) * | 2001-04-24 | 2005-06-14 | Supergen, Inc. | Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase |
-
2005
- 2005-02-25 CA CA002557075A patent/CA2557075A1/fr not_active Abandoned
- 2005-02-25 EP EP05723859A patent/EP1718150A1/fr not_active Withdrawn
- 2005-02-25 AU AU2005216971A patent/AU2005216971A1/en not_active Abandoned
- 2005-02-25 WO PCT/US2005/006173 patent/WO2005082144A1/fr active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005216971A1 (en) | 2005-09-09 |
| EP1718150A1 (fr) | 2006-11-08 |
| WO2005082144A1 (fr) | 2005-09-09 |
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