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CA2331414A1 - Transdermal therapeutic system for the administration of candesartan - Google Patents

Transdermal therapeutic system for the administration of candesartan Download PDF

Info

Publication number
CA2331414A1
CA2331414A1 CA002331414A CA2331414A CA2331414A1 CA 2331414 A1 CA2331414 A1 CA 2331414A1 CA 002331414 A CA002331414 A CA 002331414A CA 2331414 A CA2331414 A CA 2331414A CA 2331414 A1 CA2331414 A1 CA 2331414A1
Authority
CA
Canada
Prior art keywords
candesartan
administration
therapeutic system
transdermal therapeutic
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002331414A
Other languages
French (fr)
Other versions
CA2331414C (en
Inventor
Thomas Strungmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hexal AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2331414A1 publication Critical patent/CA2331414A1/en
Application granted granted Critical
Publication of CA2331414C publication Critical patent/CA2331414C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a transdermal system containing an active ingredien t and used for the administration of candesartan or its pharmaceutically compatible esters and salts.
CA002331414A 1998-05-06 1999-05-04 Transdermal therapeutic system for the administration of candesartan Expired - Fee Related CA2331414C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19820151A DE19820151A1 (en) 1998-05-06 1998-05-06 Transdermal therapeutic system for the application of candesartan
DE19820151.6 1998-05-06
PCT/EP1999/003029 WO1999056734A2 (en) 1998-05-06 1999-05-04 Transdermal therapeutic system for the administration of candesartan

Publications (2)

Publication Number Publication Date
CA2331414A1 true CA2331414A1 (en) 1999-11-11
CA2331414C CA2331414C (en) 2008-09-16

Family

ID=7866803

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002331414A Expired - Fee Related CA2331414C (en) 1998-05-06 1999-05-04 Transdermal therapeutic system for the administration of candesartan

Country Status (8)

Country Link
EP (1) EP1085858B1 (en)
JP (1) JP4659982B2 (en)
AT (1) ATE280575T1 (en)
AU (1) AU760550B2 (en)
BR (1) BR9910201A (en)
CA (1) CA2331414C (en)
DE (2) DE19820151A1 (en)
WO (1) WO1999056734A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8101599B2 (en) 2002-05-17 2012-01-24 Novartis Ag Pharmaceutical composition containing anti-hypertensive agents
CN104356116A (en) * 2014-10-17 2015-02-18 北京理工大学 Preparation method of organic amine salt and ammonia salt of candesartan

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2363792C (en) 1999-02-19 2009-10-27 Takeda Chemical Industries, Ltd. Percutaneous absorption preparation of compound having angiotensin ii antagonistic activity
WO2005070463A2 (en) * 2004-01-12 2005-08-04 Sepracor, Inc. Compositions comprising (s)-amlodipine malate and an angiotensin receptor blocker and methods of their use
WO2005079751A2 (en) * 2004-01-23 2005-09-01 Ranbaxy Laboratories Limited Oral pharmaceutical compositions of candesartan cilexetil
EP1997479A1 (en) * 2007-05-31 2008-12-03 Helm AG Stabilized amorphous candesartan cilexetil compositions for oral administration
JP5308788B2 (en) * 2008-11-27 2013-10-09 興和株式会社 Patch
AU2010270603B2 (en) * 2009-07-07 2015-05-07 Convatec Technologies Inc. Pressure sensitive silicone adhesives with amphiphilic copolymers

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH674618A5 (en) * 1987-04-02 1990-06-29 Ciba Geigy Ag
US4898732A (en) * 1988-05-04 1990-02-06 The Clinipad Corporation Inhibiting of tumor growth with an antagonist of the renin-angioten-sin system
DE58906975D1 (en) * 1988-08-02 1994-03-24 Ciba Geigy Multi-layer plaster.
DE69010076T2 (en) * 1989-05-25 1994-12-08 Takeda Chemical Industries Ltd Transdermal therapeutic agent.
US5196444A (en) * 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
GB2256135B (en) * 1991-05-31 1995-01-18 Orion Yhtymae Oy Transdermal administration of 4-substituted imidazoles
CA2115985A1 (en) * 1993-02-25 1994-08-26 Kohei Nishikawa Vascular hypertrophy suppressor
DE4341444C2 (en) * 1993-12-04 1996-03-14 Lohmann Therapie Syst Lts Active substance-containing plaster and process for its production
DE19512181C2 (en) * 1995-03-31 2003-11-06 Hexal Pharma Gmbh Transdermal system with ramipril and / or trandolapril as an ACE inhibitor
JPH08310946A (en) * 1995-05-19 1996-11-26 Yuutoku Yakuhin Kogyo Kk Percutaneous absorbable pharmaceutical preparation
FR2735365B1 (en) * 1995-06-14 1997-09-05 Sanofi Sa USE OF AN ANGIOTENSIN II ANTAGONIST AND A BENZOFURANE DERIVATIVE FOR THE PREPARATION OF A MEDICAMENT USEFUL IN THE TREATMENT OF CARDIOVASCULAR CONDITIONS
FR2746013B1 (en) * 1996-03-18 1998-05-29 Sanofi Sa USE OF ANTIARRHYTHMIC COMPOUNDS IN THE PREVENTION OF POST INFARCT MORTALITY
JP4346696B2 (en) * 1996-05-28 2009-10-21 久光製薬株式会社 Transdermal therapeutic device
DE19626621A1 (en) * 1996-07-02 1998-01-08 Hexal Ag Plaster for transdermal application of pergolide
JPH11315034A (en) * 1998-03-04 1999-11-16 Takeda Chem Ind Ltd Sustained release preparation of compound having angiotensin ii antagonism, its production and use

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8101599B2 (en) 2002-05-17 2012-01-24 Novartis Ag Pharmaceutical composition containing anti-hypertensive agents
CN104356116A (en) * 2014-10-17 2015-02-18 北京理工大学 Preparation method of organic amine salt and ammonia salt of candesartan

Also Published As

Publication number Publication date
JP2002513753A (en) 2002-05-14
EP1085858B1 (en) 2004-10-27
CA2331414C (en) 2008-09-16
ATE280575T1 (en) 2004-11-15
DE59910944D1 (en) 2004-12-02
JP4659982B2 (en) 2011-03-30
DE19820151A1 (en) 1999-11-11
WO1999056734A3 (en) 2000-01-27
BR9910201A (en) 2001-01-09
AU760550B2 (en) 2003-05-15
AU3931199A (en) 1999-11-23
EP1085858A2 (en) 2001-03-28
WO1999056734A2 (en) 1999-11-11

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20180504