CA2386572A1 - A toothbrush with individually embedded bristles - Google Patents
A toothbrush with individually embedded bristles Download PDFInfo
- Publication number
- CA2386572A1 CA2386572A1 CA002386572A CA2386572A CA2386572A1 CA 2386572 A1 CA2386572 A1 CA 2386572A1 CA 002386572 A CA002386572 A CA 002386572A CA 2386572 A CA2386572 A CA 2386572A CA 2386572 A1 CA2386572 A1 CA 2386572A1
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- Canada
- Prior art keywords
- bristles
- toothbrush
- type
- bristle
- diameter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B3/00—Brushes characterised by the way in which the bristles are fixed or joined in or on the brush body or carrier
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B15/00—Other brushes; Brushes with additional arrangements
- A46B15/0002—Arrangements for enhancing monitoring or controlling the brushing process
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B15/00—Other brushes; Brushes with additional arrangements
- A46B15/0002—Arrangements for enhancing monitoring or controlling the brushing process
- A46B15/0016—Arrangements for enhancing monitoring or controlling the brushing process with enhancing means
- A46B15/0032—Arrangements for enhancing monitoring or controlling the brushing process with enhancing means with protrusion for polishing teeth
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- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B9/00—Arrangements of the bristles in the brush body
- A46B9/005—Arrangements of the bristles in the brush body where the brushing material is not made of bristles, e.g. sponge, rubber or paper
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B9/00—Arrangements of the bristles in the brush body
- A46B9/02—Position or arrangement of bristles in relation to surface of the brush body, e.g. inclined, in rows, in groups
- A46B9/028—Bristle profile, the end of the bristle defining a surface other than a single plane or deviating from a simple geometric form, e.g. cylinder, sphere or cone
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B9/00—Arrangements of the bristles in the brush body
- A46B9/02—Position or arrangement of bristles in relation to surface of the brush body, e.g. inclined, in rows, in groups
- A46B9/04—Arranged like in or for toothbrushes
-
- A—HUMAN NECESSITIES
- A46—BRUSHWARE
- A46B—BRUSHES
- A46B2200/00—Brushes characterized by their functions, uses or applications
- A46B2200/10—For human or animal care
- A46B2200/1066—Toothbrush for cleaning the teeth or dentures
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- Physics & Mathematics (AREA)
- Geometry (AREA)
- Brushes (AREA)
Abstract
An improved toothbrush is disclosed. The toothbrush contains bristles which are individually embedded in a toothbrush head and mutually spaced apart from one another by a distance from 0.5 times to 10 times the diameter of the bristles. The bristles may include first type bristles having a diameter of from about 0.25 mm to about 0.60 mm; second type bristles having a diameter of from about 0.08 mm to about 0.35 mm and a free length of from about 7 mm to about 16 mm; third type bristles having a diameter of from about 0.15 mm to about 0.40 mm and a free length of from about 5 mm to about 14 mm; fourth type bristles having a diameter of from about 0.15 mm to about 1.0 mm and a free length of from about 9 mm to about 15 mm; and a dense tuft of bristles at the end of the toothbrush head distal from the handle.
Description
A
A TOOTHBRUSH WITH INDIVIDUALLY EMBEDDED BRISTLES
This is a continuation-in-part of Application Serial No.
09/461,891, filed December 15, 1999.
J
This invention relates co a toothbrush. The toothbrush is characterized by standing plastic bristles which are individually embs=_dded in the head of the toothbrush at a small distance from each other. Within the head of a ~.o single toothbrush, several different bristle arrangements may exist, each with a unique oral cavity functional purpose.
Conventional toothbrushes are manufactured by attaching ::5 groups of bristles ("tufts") to the plastic head of the toothbrush. The tufts can be adhered in many ways. In one well-known method, each tuft is formed from a plurality of individual bristles folded into a U-shaped configuration. The folded tufts are then inserted into zo apertures, or cavities, provided in the head of the toothbrush. Eac:h.folded tuft is held in place in its respective cavity by inserting a small piece of metal (called an "anchor" or "staple") into the cavity such that the bottom portion of the U-shaped tuft is located 2s and secured between the bottom of the cavity and the staple. That portion of each folded tuft which is secured in its respective cavity is sometimes Lef~rred to as the "br_i~:t'e rots". See, e.g., U.S. 3,590,438, ~fDC-375 the disclosure of which is hereby incorporated by reference. Each tuft is made up of anywhere from 2-60 individual bristles typically having a diameter of about 0.15 to about 0.25 mm and a length of 7 to 13 mm, depending on the manufacturer's design and toothbrush type. For example, a "soft" bristled toothbrush may have different length and diameter bristles than a "medium" bristled toothbrush will have.
io In another method of manufacture, each tuft again comprises a plurality of individual bristles. A number of .bristle tufts, each of the. tufts comprising a plurality of individual bristles, are inserted into respective holes in a first mold member such that a is length of the tuft protrudes from a side of the mold member which will subsequently form an inner surface of the mold cavity for the brush body. At least a portion of the protruding length of each tuft is then fused into a mass having a larger cross-section than that of the 2o holes at the inner side of the first mold member. The first maid member is then mated with a second mold member to def ine the mold cavity for the brush body and molding material is injected into the cavity to form the final brush pi°oduct. See, e.g., U.S. 4,635,313, the 25 disclosure of which is hereby incorporated by reference.
This method allows for the creation of complex and asymmetric tuft. patterns that may be denser than the standard stapled tuft.
s Another method of fastening bristle tufts to a bristle carrier is disclosed in WO 93/12690, the disclosure of which is hereby incorporated by reference.
One problem associated with toothbrushes manufactured to with tufted bristles is that bristles incorporated into the tuft structure are not free to bend and flex independently. Thus tufted bristles cannot clean as efficiently as bristles which are free to independently follow the irregular contours along the tooth's is structure. Further, the structure of the tuft limits the freedom of motion of the individual bristles, especially oven the cusps, grooves and other varied terrain of the tooth structure. In addition, the interproximal access of the bristle is limited by the 2o bulky diameter of the densely packed bristle tufts.
Another problem associated with toothbrushes manufactured with bristles in tufts is that after being used, the toothbrushes frequently do not dry out z5 sufficiently prior to their next use. This is because the bristles are combined into bundles, which creates narrow capillaries between the bristles. The moisture from using the toothbrush may be preserved for an extended period of time in the narrow capillaries between the bristles. The moisture may provide conditions under which bacteria and microbes may grow.
If the toothbrush is used at least twice per day, as recommended by dental professionals, the period between uses may not be long enough to allow for sufficient drying. The problem is particularly noted in the region situated near the head of the toothbrush where the bristles are attached. This effect is additionally io promoted by dirt particles or residues of application media, namely toothpaste, that remain in the narrow capillaries and cannot be adequately removed. The relatively close spacing of the bristles within the root region may lead to incomplete removal of toothpaste residue when the toothbrush is rinsed after use.
Therefore, there is a need for a toothbrush which provides efficient tooth cleaning, is itself easily cleaned, and dries in a relatively short period of time.
World Patent Application No. WO 96/27308 describes an article which contains a bristle carrier as well as a bristle covering. The bristle covering contains individual plastic bristles that do not contact one another. The reference teaches that the flexural stiffness of the bristles is critic~:l to the effectiveness of the toothbrush. The stiffness of the _ 5 -entire bristle covering can be varied not only by choosing varyine bristle dimensions (diameter, length) and bristle materials, but also by choosing slightly varying spacing between the bristles. The bristles may be spaced apart: by about 0.5 times to 4 times, in particular 1.5 t:o 2 times, the bristle diameter, based on the space between the exterior adjacent surfaces of the bristles. ':Che bristles may also have a varying stiffness, for example varying diameters and/or spacing, io wherein groups of bristles have the same stiffness within a group but a different stiffness from another bristle group. The bristles may be of varying lengths from the bristle carrier to the free end of the bristle.
The bristles may be structured, flocked or coated on i5 their surfaces . Also, the free ends of the bristles may be shaped.
As used herein, the term "free end" means the end of the bristle distal to the point where the bristle is 2o attached to the toothbrush head.
In conventional toothbrushes, stiffness is substantially determined by t:he length of the tufts and the bristle packing density in the tuft, as well as by the diameter z5 of the individual bristles . This latter factor has the least impact because the bristles are mutually supportive in the tuft as a result of which the flexural stiffness of the tuft is several times greater '7DC-375 than that of the individual bristle. Due to the separation distance between bristles in the article taught in WO 96/27308, the bristle diameter plays a much larger role in determining stiffness than when the s bristles are in tufts. WG 96/27308 does not teach appropriate brig>tle lengths or diameters, the two most important factors in determining the bristle stiffness.
to World Patent Application No. WO 99/07252 describes a toothbrush having a plastic bristle head and standing plastic bristle; which are individually embedded in the bristle head. The bristles are mutually spaced apart by a small distance. The distance is specified only in i5 that the bristle' packing density is 400 to 800 bristles per square centimeter on the brush head. The reference discloses that a bristle density of 600 bristles per square centimeter is preferred. The reference further discloses bristles between about 0.095 mm and about 20 0.225 mm in diameter. The reference teaches: that the shorter the frees length of the bristle, the smaller the diameter selected to maintain stiffness; an overall height of the toothbrush in the region of the bristle head of between 6.5 mm and 11 mm; a thickness of the 25 bristle head of between 1.5 mm and 3 mm; and bristles of mm to 9.5 mm in free length. Since the flexural stiffness of an individual bristle is significantly less than that of a tuft comprising a plurality of bristles ~JDC-375 _ 7 _ of the same height and diameter, this patent application discloses the base of a shorter bristle with equivalent diameter to conventional tufted brush bristles. The toothbrush with the individual bristles further makes it possible to vary the flexural stiffness in precise graduations by altering the spacing of the bristles.
A TOOTHBRUSH WITH INDIVIDUALLY EMBEDDED BRISTLES
This is a continuation-in-part of Application Serial No.
09/461,891, filed December 15, 1999.
J
This invention relates co a toothbrush. The toothbrush is characterized by standing plastic bristles which are individually embs=_dded in the head of the toothbrush at a small distance from each other. Within the head of a ~.o single toothbrush, several different bristle arrangements may exist, each with a unique oral cavity functional purpose.
Conventional toothbrushes are manufactured by attaching ::5 groups of bristles ("tufts") to the plastic head of the toothbrush. The tufts can be adhered in many ways. In one well-known method, each tuft is formed from a plurality of individual bristles folded into a U-shaped configuration. The folded tufts are then inserted into zo apertures, or cavities, provided in the head of the toothbrush. Eac:h.folded tuft is held in place in its respective cavity by inserting a small piece of metal (called an "anchor" or "staple") into the cavity such that the bottom portion of the U-shaped tuft is located 2s and secured between the bottom of the cavity and the staple. That portion of each folded tuft which is secured in its respective cavity is sometimes Lef~rred to as the "br_i~:t'e rots". See, e.g., U.S. 3,590,438, ~fDC-375 the disclosure of which is hereby incorporated by reference. Each tuft is made up of anywhere from 2-60 individual bristles typically having a diameter of about 0.15 to about 0.25 mm and a length of 7 to 13 mm, depending on the manufacturer's design and toothbrush type. For example, a "soft" bristled toothbrush may have different length and diameter bristles than a "medium" bristled toothbrush will have.
io In another method of manufacture, each tuft again comprises a plurality of individual bristles. A number of .bristle tufts, each of the. tufts comprising a plurality of individual bristles, are inserted into respective holes in a first mold member such that a is length of the tuft protrudes from a side of the mold member which will subsequently form an inner surface of the mold cavity for the brush body. At least a portion of the protruding length of each tuft is then fused into a mass having a larger cross-section than that of the 2o holes at the inner side of the first mold member. The first maid member is then mated with a second mold member to def ine the mold cavity for the brush body and molding material is injected into the cavity to form the final brush pi°oduct. See, e.g., U.S. 4,635,313, the 25 disclosure of which is hereby incorporated by reference.
This method allows for the creation of complex and asymmetric tuft. patterns that may be denser than the standard stapled tuft.
s Another method of fastening bristle tufts to a bristle carrier is disclosed in WO 93/12690, the disclosure of which is hereby incorporated by reference.
One problem associated with toothbrushes manufactured to with tufted bristles is that bristles incorporated into the tuft structure are not free to bend and flex independently. Thus tufted bristles cannot clean as efficiently as bristles which are free to independently follow the irregular contours along the tooth's is structure. Further, the structure of the tuft limits the freedom of motion of the individual bristles, especially oven the cusps, grooves and other varied terrain of the tooth structure. In addition, the interproximal access of the bristle is limited by the 2o bulky diameter of the densely packed bristle tufts.
Another problem associated with toothbrushes manufactured with bristles in tufts is that after being used, the toothbrushes frequently do not dry out z5 sufficiently prior to their next use. This is because the bristles are combined into bundles, which creates narrow capillaries between the bristles. The moisture from using the toothbrush may be preserved for an extended period of time in the narrow capillaries between the bristles. The moisture may provide conditions under which bacteria and microbes may grow.
If the toothbrush is used at least twice per day, as recommended by dental professionals, the period between uses may not be long enough to allow for sufficient drying. The problem is particularly noted in the region situated near the head of the toothbrush where the bristles are attached. This effect is additionally io promoted by dirt particles or residues of application media, namely toothpaste, that remain in the narrow capillaries and cannot be adequately removed. The relatively close spacing of the bristles within the root region may lead to incomplete removal of toothpaste residue when the toothbrush is rinsed after use.
Therefore, there is a need for a toothbrush which provides efficient tooth cleaning, is itself easily cleaned, and dries in a relatively short period of time.
World Patent Application No. WO 96/27308 describes an article which contains a bristle carrier as well as a bristle covering. The bristle covering contains individual plastic bristles that do not contact one another. The reference teaches that the flexural stiffness of the bristles is critic~:l to the effectiveness of the toothbrush. The stiffness of the _ 5 -entire bristle covering can be varied not only by choosing varyine bristle dimensions (diameter, length) and bristle materials, but also by choosing slightly varying spacing between the bristles. The bristles may be spaced apart: by about 0.5 times to 4 times, in particular 1.5 t:o 2 times, the bristle diameter, based on the space between the exterior adjacent surfaces of the bristles. ':Che bristles may also have a varying stiffness, for example varying diameters and/or spacing, io wherein groups of bristles have the same stiffness within a group but a different stiffness from another bristle group. The bristles may be of varying lengths from the bristle carrier to the free end of the bristle.
The bristles may be structured, flocked or coated on i5 their surfaces . Also, the free ends of the bristles may be shaped.
As used herein, the term "free end" means the end of the bristle distal to the point where the bristle is 2o attached to the toothbrush head.
In conventional toothbrushes, stiffness is substantially determined by t:he length of the tufts and the bristle packing density in the tuft, as well as by the diameter z5 of the individual bristles . This latter factor has the least impact because the bristles are mutually supportive in the tuft as a result of which the flexural stiffness of the tuft is several times greater '7DC-375 than that of the individual bristle. Due to the separation distance between bristles in the article taught in WO 96/27308, the bristle diameter plays a much larger role in determining stiffness than when the s bristles are in tufts. WG 96/27308 does not teach appropriate brig>tle lengths or diameters, the two most important factors in determining the bristle stiffness.
to World Patent Application No. WO 99/07252 describes a toothbrush having a plastic bristle head and standing plastic bristle; which are individually embedded in the bristle head. The bristles are mutually spaced apart by a small distance. The distance is specified only in i5 that the bristle' packing density is 400 to 800 bristles per square centimeter on the brush head. The reference discloses that a bristle density of 600 bristles per square centimeter is preferred. The reference further discloses bristles between about 0.095 mm and about 20 0.225 mm in diameter. The reference teaches: that the shorter the frees length of the bristle, the smaller the diameter selected to maintain stiffness; an overall height of the toothbrush in the region of the bristle head of between 6.5 mm and 11 mm; a thickness of the 25 bristle head of between 1.5 mm and 3 mm; and bristles of mm to 9.5 mm in free length. Since the flexural stiffness of an individual bristle is significantly less than that of a tuft comprising a plurality of bristles ~JDC-375 _ 7 _ of the same height and diameter, this patent application discloses the base of a shorter bristle with equivalent diameter to conventional tufted brush bristles. The toothbrush with the individual bristles further makes it possible to vary the flexural stiffness in precise graduations by altering the spacing of the bristles.
2 also states that the individual bristle toothbrushes provide a gap-free surface, which is Lo desirable in terms of cleaning. This is an advantage to the individual bristle technology. Since each bristle is capable of independent movement, more of the small irregularities in the tooth structure can be cleaned at one time. The entire surface of the a5 toothbrush bristles is used to clean more efficiently to provide a better overall clean versus conventional tufted brushes. Although the total number of bristles on the conventional toothbrush is roughly equivalent to the overall number of bristles on the new individual zo bristle toothbrush, the new toothbrush is perceived to have over 1000 cleaning surfaces (individual bristles) versus 40 to 50 cleaning surfaces (tufts) on the conventional toothbrush.
z5 Typical bristles in a soft tufted toothbrush have a diameter of about 0.15 mm to about 0.25 mm and free lengths from about 8 mm to about 12 mm. T::e dimensions disclosed in t;he references above are very similar to ~JDC - 3 7 5 _ g ._ those used in conventional tufted brushes, but because the bristles in the references are individually embedded, the flexural stiffness is substantially less than the flexura7_ stiffness of a conventional toothbrush s whose individual bristle tufts comprise a plurality of bristles. Therefore, the toothbrush with individual bristles embedded in the head as taught in the foregoing references presents several problems for the consumer.
One problem is that, although some flex is desired in io the bristle to adapt to the contours of the irregular tooth structure, too much flex. is not beneficial in that if the bristle is too soft, it will not be able to adequately clean the teeth. There will not be enough strength in the bristle to sweep away the plaque, food i5 debris, etc. Although one certainly does not want to make a bristle that is so stiff that it may injure the soft or hard oral tissues, a certain amount of stiffness is nevertheless required to perform the toothbrush's cleaning function.
A second problem associated with the toothbrushes disclosed in th.e references above is that they are perceived by the consumer as being too soft and unable to clean as well as somewhat stiffer toothbrushes.
Although it is not desirable to make a toothbrush that is so stiff that it could cause damage to the oral tissues, some minimal degree of stiffness is required to provide both actual cleaning and a perception in the consumer's mind that cleaning is being accomplished. A
consumer may believe that a toothbrush that is too soft is not capable of removing plaque, food debris, etc.
from the teeth.. The flexural stiffness of a single s bristle used in a tufted toothbrush is too low when used individually to provide the consumer with a perception that cleaning is actually being effected.
A third problem associated with the toothbrushes Z.o disclosed in the references above is that, because the flexural stiffness of the individual bristle is much less .than that of a tuft comprised of a plurality of identical bristles, and since there are no supporting bristles about t:he periphery to return the bristle to ~.s the upright position after deflection, the individual bristles are likely to no longer appear to be in an upright, generally perpendicular position after use.
Instead, the bristles will bend in all directions from the toothbrush head ("splay") after significantly fewer :>o uses than in a tufted toothbrush. A splayed toothbrush is seen by the consumer as worn and used. Clinical studies in the literature have also shown that these splayed toothbrushes do not clean as well as an identical toothbrush that contains new, upright z5 bristles.
A fourth problem associated with the toothbrushes disclosed =n '=~e references above is that, upon ~rDC-375 inspection by the consumer, it is believed that the toothbrush will. not last as long as a tufted toothbrush.
The toothbrush containing spaced apart, individual bristles is perceived as not having the same resiliency as a tufted toothbrush and thus will need to be replaced sooner. This is mostly due to the perception that there are no other bristles helping to maintain each bristle upright. Since the splaying effect is also the main cue to the consumer that the toothbrush needs to be io replaced, the product is undesirable for purchase due to the perceived shorter product life.
Therefore, despite the disclosure of the above-mentioned references, there is a continuing need for a toothbrush is which provides efficient tooth cleaning, is easily cleaned, and dries in a relatively short period of time.
we have surprisingly found that toothbrushes which employ larger d_~ameter bristles having a length similar to the length of the tufts in tufted toothbrushes will 2o solve or greatly reduce the problems described above. A
thicker bristle of similar length to that used in conventioiral tufted toothbrushes will not only supply more rigidity to the toothbrush, thus providing a more perceivable scrubbing feeling to the user, but will also 2s maintain the bristle length that is required to reach the interdental and subgingival areas. The thicker bristle will inherently have more structural support to resist splaying and retain its upright shape for a longer period o:E time relative to a smaller diameter, equal length bristle.
In one embodime>.nt, the present invention provides a s toothbrush having: a handle; a toothbrush head distal to the handle; and a multiplicity of first type bristles, each bristle having a diameter of from about 0.25 mm to about 0.60 mm; wherein the first type bristles are individually secured, e.g., by embedding in the Lo toothbrush head; and the bristles are mutually spaced apart from one another by a distance from 0.5 times to times the diameter of the bristles.
The toothbrush handle (1) and toothbrush head (2) may be i5 made in one piece by inj ection molding . The toothbrush head (2) is d~.stal to the toothbrush handle (1). The toothbrush handle (1) and toothbrush head (2) may be made of polymers such as, but not limited to, polyethylene, polypropylene, and polycarbonate.
2o The first type bristles (3) and any other bristles utilized in this invention may be made from a material selected from a:n elastomeric material such as, but not limited to, rubber and a polymer selected from the group 25 consisting of: nylon, polyamides, polyesters, polybutylene terephthalate, polypropylene, acetal resins, fluoropolymers, polyacrylates, and polysulfones.
The first type bristles and any other bristles utilized ~JDC-375 within this invention may be structured, flocked or coated on their surface area. The first type bristles and any other bristles utilized in this invention may contain additi've's such as, but not limited to abrasives s and polishing agents; anti-cavity agents such as sodium fluoride; antimicrobial agents, and combinations thereof.
In the first embodiment of the invention, it is Zo preferred that 'the first type bristles (3) all have the same free length. As used herein, the term "free length" means the length of the bristle from inner surface (9) of the toothbrush head to the free end of the bristle. The space between the exterior surfaces of i5 adjacent first type bristles (4) and the diameter of the first type bristles may be varied such that a first type bristle packing density of from 50 per cmz to 1000 per cm2 is obtained. Each first type bristle (3) is individually embedded in the head of the toothbrush (2).
2o The first type bristles (3) as well as any other bristles utilized herein may be secured to the toothbrush head (2) by any process known in the art, including those mentioned hereinabove, or by a bonding method wherein an adhesive is utilized to attach the 25 bristles to the toothbrush head.
A combination of first type bristle diameters ranging from about 0.25 mm to about 0.60 mm, and spacing between immediately adjacent bristles ranging from about 0.5 times to about 10 times, preferably about 0.5 times to about 4 times, the diameter of the first type bristles (3) or any other bristles utilized in this invention may s be utilized t=o provide different sensations for different parts of the mouth. For example, the first type bristles (3) may be arranged such that at least one section of the toothbrush head (2) contains first type bristles (3) having diameters ranging from about 0.35 mm to to about 0.60 rnm, while at least one other section of the toothbrush head (2) contains first type bristles (3) having diameters ranging from about 0.25 mm to about 0.35 mm.
is The toothbrush may further include at least one dense tuft (8) of bristles. The skilled art worker will recognize that dense tuft (8) of bristles may be secured to the toothbrush head (2) by means known in the art, such as, but: not limited to, fusion or stapling 2o techniques. The bristles in this tuft may have diameters ranging from about 0.08 mm to about 0.40 mm and a free length ranging from about 7 mm to about 15 mm. The dense tuft (8) of bristles may be arranged anywhere on the' toothbrush head (2). Preferably, the 25 dense tuft (8) of bristles is distal to the toothbrush handle (1). Preferably, when the dense tuft (8) is distal to the toothbrush handle, the dense tuft has a longer length than that of the bristles comprising the toothbrush.
In a second embodiment of the present invention, the toothbrush comprises: a handle; a toothbrush head distal to the handle; at least one second type bristle having a diameter of from about 0.08 mm to about 0.35 mm and a free length of.from about 7 mm to about 16 mm; and at least one third type bristle having a diameter of from to about 0.15 mm to about 0.40 mm and a free length of from about 5 mm to about 14 mm; wherein the trim difference between the second type bristle and the third type bristle ranges from about 0.5 mm to about 3 mm. This toothbrush is believed to provide enhanced cleaning i5 performance .
The second type. of bristle (5) must have a diameter which is sufficiently large to provide the bristle with enough inherent stiffness to be able to remove plaque, 2o food debris, E~tc. from the teeth while remaining flexible enough to follow the contour of the oral surfaces during use. For this purpose, the second type of bristle (5) may have a diameter of from about 0.08 mm to about 0.35 mm, preferably from about 0.13 mm to about 25 0.35 mm, and a free length of from about 7 mm to about 16 mm, preferably from about 9 mm to about 14 mm. The second type bristles (5) may serve the purpose ;.f interdental and subgingival cleaning.
~JDC - 3 7 5 The third type of bristle (6) may serve the purpose of cleaning the surfaces of the teeth. The third type of bristle (6) may have a diameter of from about 0.15 mm to about 0.40 mm, preferably from about 0.20 mm to about s 0.40 mm and a free length of from about 5 mm to about 14 mm, preferably from about 7 mm to about 12 mm. A
trim difference of from about 0.5 mm to about 3 mm is recommended between the free lengths of the second type (5) and third type (6) of bristles to ensure optimal io cleaning interdentally and subgingivally. As used herein, the term "trim difference" means the difference in free lengths between different types of bristles.
The free lengths of the bristles within a given section i5 of the toothbrush may be varied to also provide an improved perception of cleaning via visual and tactile stimuli. For example, a sawtooth cut or a zigzag cut reinforces the consumer's perception of interdental cleaning. Other patterns, such as but not limited to, 2o waves, arcs, etc. , can be used in place of the sawtooth cut or zigzag cut .
In one embodiment of the present invention, alternating sections of second type (5) and third type (6) bristles 25 are contained in the toothbrush to enhance interproximal cleaning efficacy. In this embodiment, second type :gristles (5), which may have a diameter of from about O.Of3 mm to abour_ 0.35 mm, preferably from about 0.13 mm to about 0.35 mm, and a free length of from about 7 mm to about 16 mm, preferably from about 9 mm to about 14 mm, may be <alternated with third type bristles (6), which may have a diameter of from about s 0.15 mm to about: 0.40 mm, preferably from about 0.20 mm to about 0.40 mrn, and a free length of from about 5 mm to about 14 mm, preferably from about 7 mm to about 12 mm. The first sections contain second type bristles, and the second sections contain third type bristles.
io The sections may be from 1 to 7 rows deep. If each section is spaced at 2.15 times the diameter of each adjacent bristle' and the transition is spaced at 2.15 times the average diameter of the adjoining bristles, the density of: the third type bristle section may be i5 380-600 bristles per square centimeter while the density of the second type bristle section may be 100-350 bristles per square centimeter. The lower density of bristles is preferred since it allows for the use of thicker diameter bristles, which provide more cleaning 2o sensation to the consumer.
Other patterns besides alternating rows may also be used for the varying length and diameter bristles and these include, but are not limited to alternating waves, a 25 circle of lon<~er bristles surrounding the shorter bristles along a row, a hexagon of longer bristles surrounding a ~h.orter bristlE, e:.c.
~JDC-375 In another embodiment of the present invention, at least one of a fourth type of bristle (7) is contained in at least one section about the periphery of the toothbrush head (2). As used herein, by "periphery" is meant the s outer edge of the upper surface of the toothbrush head.
Elastomeric material such as, but not limited to rubber may be particularly suited as the material of construction for the fourth type of bristle. The fourth type bristles (7) may be of a diameter of from about io 0.15 mm to about 1.0 mm, preferably about 0.30 mm to about 0.50 mm, and a free length of from about 9 mm to about 15 mm, preferably from about 10 mm to about 13 mm.
In a preferred embodiment, a plurality of fourth type bristles (7) are arranged about the periphery of the i5 toothbrush head. The free length of the fourth type bristles (7) may also alternate along the periphery of the toothbrush head, resulting in forms. Possible forms include, but are. not limited to an arc shape, a sawtooth shape, or a wave shape. Combinations of these height 2o patterns are possible as well, as are repeating patterns, such as a series of smaller arcs along the periphery or a ~;awtooth with an arcing midline.
The present invention may also provide a toothbrush z5 having a multiplicity of bristle diameters and bristle spacing (4) within the toothbrush head (2) to provide different sensations for different parts of tr.2 mouth.
Depending or. the ratio of the: different bristles used of each diameter, and the spacing (4) used between bristles, the bristle density on the toothbrush head (2) can be varied from 50 to 1000 per square centimeter.
The bristle density could also vary along various s regions of the toothbrush head (2) such that one area may have a different bristle density than that of another area t.o provide the customer with desired tactile perception and visual cues.
to The toothbrush may further include at least one dense tuft (8) of bri~;tles. The bristles in the tuft may have diameters ranging from about 0.08 mm to about 0.40 mm and a free length ranging from about 7 mm to about 15 mm. The dense tuft (8) of bristles may be arranged 15 anywhere on the toothbrush head (2). In one embodiment, the toothbrush includes at least one dense tuft with first type bristles; second type bristles; third type bristles; fourth type bristles; or combinations thereof.
The dense tuft or tufts may be of any shape. In top 2o plan, the dense tuft or tufts may be, for example, in the form of a circle, square, oval, triangle, elongated rectangle, polygonal, half-moon, horseshoe, bar, stars, arc and combinations thereof. Preferably, a dense tuft (8) of bristles is located at the tip of the free end of 25 the brush head of the toothbrush to aid in cleaning the posterior teeth.
~JDC-375 In a preferred embodiment, the present invention provides a toothbrush wherein the toothbrush head (2) contains second type bristles (5) which may have a diameter of from about 0.08 mm to about 0.35 mm, preferably from about 0.13 mm to about 0.35 mm, and a free length of from about 7 mm to about 16 mm, preferably from about 9 mm to about 14 mm throughout the toothbrush head (2; third type bristles (6) which may have a diameter of from about 0.15 mm to about 0.40 mm, ~~o preferably from about 0.20 mm to about 0.40 mm, and a free length of from about 5 mm to about 14 mm, preferably from about 7 mm to about 12 mm; and fourth type bristles (';~) having a diameter of from about 0.15 mm to about 1.0 mm, preferably about 0.30 mm to about L5 0.50 mm, and a Eree length of from about 9 mm to about mm, preferably about 10 mm to about 13 mm along the periphery of the toothbrush head (2). The toothbrush head contains a periphery and a distal end. At the distal end of the toothbrush head (2) is a dense tuft :zo (8) of bristles for cleaning of the back teeth and gums.
The bristles in the dense tuft (8) may have diameters ranging f rom about 0 . 0 8 mm to about 0 . 4 0 mm and a free length ranging from about 7 mm to about 15 mm. With the varying bristle patterns within this toothbrush, z5 consumers receive not. only a superior cleaning of their entire oral cavity (teeth surfaces, gums, interproximal regions, etc.) but also are able to perceive the better ~JDC-375 clean through sensual cues (visual and tactile) delivered via the bristle configuration.
Brief Description of the Drawings Descriptions of the Drawing Figures follow. The descriptions are intended to illustrate various aspects of the invention, but should not be construed as limiting the scope of the invention.
io Figure 1 displays a toothbrush having a handle (1) and a toothbrush head (2) distal to the toothbrush handle. A
multiplicity of first type bristles (3) of uniform length and diameter are embedded in the toothbrush head i5 (2). The first. type bristles (3) are mutually spaced apart from one another by a distance (4) from 0.5 times to 10 times the diameter of the bristles.
Figure 1A is a top plan view of the toothbrush shown in 2o Figure 1.
Figure 2 displays a toothbrush having second type bristles (5) and third type bristles (6) embedded in the toothbrush head (2). The bristles are mutually spaced z5 apart from one another by a distance (4) from 0.5 times to 10 times the' diameter of the bristles. The second type bristles (5) are arranged in hexugorc,l shapes around the third type bristles (6).
~JDC - 3 7 5 Figure 3 displays a toothbrush having alternating rows of second type bristles (5) and third type bristles (6) embedded in the toothbrush head (2). The bristles are mutually spaced apart from one another by a distance (4) s from o.5 times to to times the diameter of the bristles.
Figure 3A is a top plan view of the toothbrush shown in Figure 3.
io Figure 4 displays a toothbrush having alternating rows of second type bristles (5) and third type bristles (6) embedded in the toothbrush head (2). The bristles are mutually spaced (4) apart from one another by a distance from 0.5 times t.o 10 times the diameter of the bristles.
i5 Along the periphery of the toothbrush head (2) are fourth type br:i~;tles (7) embedded in the toothbrush head (2) .
Figure 4A is a top plan view of the toothbrush shown in 2o Figure 4.
Figure 5 displays a toothbrush having second type bristles (5) and third type bristles (6) embedded in the toothbrush head (2). The bristles are mutually spaced 25 apart from one another by a distance (4) from 0.5 times to 10 times the diameter of the bristles. The second type bristles (5) are arranged in hexagonal shapes around ~he third type bristles (6). At the end of the ~JDC-375 toothbrush head ( 2 ) di stal to the handle ( 1 ) , is a dense tuft of bristles (8) .
Figure 5A is a top view of the toothbrush shown in s Figure 5.
Figure 6 displays a toothbrush having second type bristles (5) and third type bristles (6) embedded in the toothbrush head (2). The bristles are mutually spaced to apart from one another by a distance (4) from 0.5 times to 10 times the diameter of the bristles. The second type bristles (5) are arranged :in hexagonal shapes around the third type bristles (6). At the end of the toothbrush head (2) distal to the handle (1) , is a dense i5 tuft of bristle=s (8). Along the periphery of the toothbrush head (2) are fourth type bristles (7) embedded ~.n the toothbrush head (2).
Figure 6A is a top view of the toothbrush shown in zo Figure 6.
Figure 7 displays a toothbrush having alternating rows of second type bristles (5) and third type bristles (6) embedded in the toothbrush head (2). The bristles are 25 mutually spaced apart from one another by a distance (4) from 0.5 times to 10 times the diameter of the bristles.
At the end of the too:hbrush head (2) distal to the handle (1), is a dense tuft of bristles (8). Along the ,7DC-375 periphery of the toothbrush head (2) are fourth type bristles (7) embedded in the toothbrush head (2).
Figure 7A is a top view of the toothbrush shown in Figure 7.
Figure 8 displays a toothbrush having randomly distributed second type bristles (5) and third type bristles (6) embedded in the toothbrush head (2). The bristles are mutually spaced apart from one another by a io distance (4) from 0.5 times to 10 times the diameter of the bristles. At the end of the toothbrush head (2) distal to the handle (1), is a dense tuft of bristles (8). Along the periphery of the toothbrush head (2) are fourth type bri:~tles (7) embedded in the toothbrush head is (2) .
Figure 8A is a top view of the toothbrush shown in Figure 8.
2o Figure 9 displays a perspective view of a toothbrush having a multiplicity of individually embedded first type bristles (:3) and a multiplicity of dense tufts (8) of bristles embedded in the toothbrush head (2).
zs Figure 9A is a top plan view of the toothbrush shown in Figure 9.
Figures 10 and 11 are perspective views of different embodiments of a toothbrush having a multiplicity of individually embedded first type bristles (3) and a multiplicity of dense tufts (8) of bristles embedded in s the toothbrush head ( 2 ) .
Figures 10A a:nd 11A are top plan views of the toothbrushes she>wn in Figures 10 and 11, respectively.
to Several example; of the invention are set forth below to further illustrate the nature of the invention and the manner of carrying it out. However, the invention should not be considered as being limited to the details thereof.
Example 1 A toothbrush wa:~ made according to the design shown in Figure 8. The bristles of the toothbrush according to 2o Figure 8 had t:he following diameters: second type bristles (5): 0.18 mm; third type bristles (6): 0.23 mm; fourth type bristles (7); 0.2 mm; and dense tuft of bristles (8): 0.25 mm. The heights of the bristles were as follows: second type bristles: 9-10 mm; third type bristles: 10.5 mm; fourth type bristles: 10-11.25 mm; and dense tuft of bristles: 12.5 mm. The space between the exterior adjacent surfaces of the second type bristles (~~) was about 0.021 -nm; the corresponding space between the exterior surfaces of the third type bristles (6) was about 0.0197 mm; the space between the exterior adjacent surfaces of the fourth type bristles (7) was about 0.018 mm; and the space between the s exterior surface: of the individual bristles comprising the dense tuft (8) of bristles was about 0.020 mm.
Two toothbrushes were made according to the design shown in Figure 11. First toothbrush (Sample 11A) had bristles of the :Following diameters: first type bristles (3): 0.20 mm; dense tufts (8) of bristles throughout the toothbrush head: 0.20 mm; and distal dense tuft (8):
of bristles 0.20 mm. The heights of the bristles were as follows: first t,irpe bristles (3) : 11 mm; dense tufts of ~_s bristles throughout the toothbrush head: 9 mm; and distal dense tuft (8) of bristles 12.5 mm. Second toothbrush (Samp:le 11B) had the following bristle diameters: first type bristles (3): 0.20 mm; dense tufts (8) of bristles throughout the toothbrush head:
20 0.18 mm; and distal dense tuft (8): of bristles 0.20 mm. The heights of the bristles were as follows: first type bristles (3): 11 mm; dense tufts (8) of bristles throughout the toothbrush head: 9 mm; and distal dense tuft (8) of bristles: 12.5 mm. In each sample 11A, 11H, the first type bristles (3) were individually embedded in toothbrush head 2.
~DC-375 The above-described three toothbrushes were tested for efficacy at cleaning between the teeth according to the procedure described in "Access to interproximal tooth surfaces by diff~=_rent bristle designs and stiffnesses of toothbrushes", Nygaard-Ostby et al., Scand. J. Dent Res.
1979, 87, 424-430, the disclosure of which is incorporated herein by reference. The results of the tests are reported in Table 1.
_.o Table 1.
Sample Between Teeth Access (mm) Figure 8 J.2 11A 11.8 11B 12.6 Oral B Cross Action 10.8 Oral B Indicator 7.7 The data above demonstrates that the toothbrushes according to the present invention clean between the teeth better than commercially available toothbrushes.
:L 5 Example 2 The efficacy of the toothbrush of Figure 8 and the Oral B* Indicator toothbrush was tested by a clinical trial.
zo An examiner-blind, randomized, crossover clinical study was conducted with seventy healthy adults. Plaque was evaluated before and after brushing for one minute using ~rDC-375 the Rustogi Modification of the Navy Plaque Index ("RMNPI"). Subjects were randomly assigned to use one of the two test. toothbrushes, namely the Oral B*
Indicator toothbrush or the toothbrush made according to the design shown in Figure 8. After brushing at the initial visit, the subjects returned two weeks later to repeat the procedure with the other of the two test toothbrushes. Evaluation of plaque using RMNPI was done at both visits. RMNPI scores were given for the whole to mouth, interproximal sites, marginal sites, behind the last molar, anterior sites, and posterior sites. The change in plaque from pre-brushing to post brushing was compared for both toothbrushes. The results are shown in Table 2.
Table 2 Plague Scores Invention* Oral B Indicator Tooth Site Pre Post delta Pre Post I delta Whole Mouth 0.64 0.30 52.8 0.64 0.36 44.1 Marginal 1 0.63 37.1 1 0.71 28.9 Interproximal 1 0.38 61.9 1 0.47 52.9 Last Molar 0.58 0.23 60 0.57 0.31 45.8 Anterior 0.65 0.30 54 0.65 0.34 48 Posterio~ 0.64 0.31 51.8 0.64 0.38 40.7 *Toothbrush of Figure 8.
The scores reported are the mean scores for the groups of participants. The term "delta" is the percent reduction in plaque for each group from before brushing to after brushing. Using statistical techniques, it was s concluded that the toothbrush of the invention removed significantly more plaque than a commercially available toothbrush from the whole mouth, gingival margin, interproximal surface, and behind the last molar, respectively 20%, 28%, 17%, and 31% more.
~. o Toothbrushes in accordance with the present invention provide efficient tooth cleaning, are easily cleaned, and dry in a rel<~tively short period of time.
vDC-375
z5 Typical bristles in a soft tufted toothbrush have a diameter of about 0.15 mm to about 0.25 mm and free lengths from about 8 mm to about 12 mm. T::e dimensions disclosed in t;he references above are very similar to ~JDC - 3 7 5 _ g ._ those used in conventional tufted brushes, but because the bristles in the references are individually embedded, the flexural stiffness is substantially less than the flexura7_ stiffness of a conventional toothbrush s whose individual bristle tufts comprise a plurality of bristles. Therefore, the toothbrush with individual bristles embedded in the head as taught in the foregoing references presents several problems for the consumer.
One problem is that, although some flex is desired in io the bristle to adapt to the contours of the irregular tooth structure, too much flex. is not beneficial in that if the bristle is too soft, it will not be able to adequately clean the teeth. There will not be enough strength in the bristle to sweep away the plaque, food i5 debris, etc. Although one certainly does not want to make a bristle that is so stiff that it may injure the soft or hard oral tissues, a certain amount of stiffness is nevertheless required to perform the toothbrush's cleaning function.
A second problem associated with the toothbrushes disclosed in th.e references above is that they are perceived by the consumer as being too soft and unable to clean as well as somewhat stiffer toothbrushes.
Although it is not desirable to make a toothbrush that is so stiff that it could cause damage to the oral tissues, some minimal degree of stiffness is required to provide both actual cleaning and a perception in the consumer's mind that cleaning is being accomplished. A
consumer may believe that a toothbrush that is too soft is not capable of removing plaque, food debris, etc.
from the teeth.. The flexural stiffness of a single s bristle used in a tufted toothbrush is too low when used individually to provide the consumer with a perception that cleaning is actually being effected.
A third problem associated with the toothbrushes Z.o disclosed in the references above is that, because the flexural stiffness of the individual bristle is much less .than that of a tuft comprised of a plurality of identical bristles, and since there are no supporting bristles about t:he periphery to return the bristle to ~.s the upright position after deflection, the individual bristles are likely to no longer appear to be in an upright, generally perpendicular position after use.
Instead, the bristles will bend in all directions from the toothbrush head ("splay") after significantly fewer :>o uses than in a tufted toothbrush. A splayed toothbrush is seen by the consumer as worn and used. Clinical studies in the literature have also shown that these splayed toothbrushes do not clean as well as an identical toothbrush that contains new, upright z5 bristles.
A fourth problem associated with the toothbrushes disclosed =n '=~e references above is that, upon ~rDC-375 inspection by the consumer, it is believed that the toothbrush will. not last as long as a tufted toothbrush.
The toothbrush containing spaced apart, individual bristles is perceived as not having the same resiliency as a tufted toothbrush and thus will need to be replaced sooner. This is mostly due to the perception that there are no other bristles helping to maintain each bristle upright. Since the splaying effect is also the main cue to the consumer that the toothbrush needs to be io replaced, the product is undesirable for purchase due to the perceived shorter product life.
Therefore, despite the disclosure of the above-mentioned references, there is a continuing need for a toothbrush is which provides efficient tooth cleaning, is easily cleaned, and dries in a relatively short period of time.
we have surprisingly found that toothbrushes which employ larger d_~ameter bristles having a length similar to the length of the tufts in tufted toothbrushes will 2o solve or greatly reduce the problems described above. A
thicker bristle of similar length to that used in conventioiral tufted toothbrushes will not only supply more rigidity to the toothbrush, thus providing a more perceivable scrubbing feeling to the user, but will also 2s maintain the bristle length that is required to reach the interdental and subgingival areas. The thicker bristle will inherently have more structural support to resist splaying and retain its upright shape for a longer period o:E time relative to a smaller diameter, equal length bristle.
In one embodime>.nt, the present invention provides a s toothbrush having: a handle; a toothbrush head distal to the handle; and a multiplicity of first type bristles, each bristle having a diameter of from about 0.25 mm to about 0.60 mm; wherein the first type bristles are individually secured, e.g., by embedding in the Lo toothbrush head; and the bristles are mutually spaced apart from one another by a distance from 0.5 times to times the diameter of the bristles.
The toothbrush handle (1) and toothbrush head (2) may be i5 made in one piece by inj ection molding . The toothbrush head (2) is d~.stal to the toothbrush handle (1). The toothbrush handle (1) and toothbrush head (2) may be made of polymers such as, but not limited to, polyethylene, polypropylene, and polycarbonate.
2o The first type bristles (3) and any other bristles utilized in this invention may be made from a material selected from a:n elastomeric material such as, but not limited to, rubber and a polymer selected from the group 25 consisting of: nylon, polyamides, polyesters, polybutylene terephthalate, polypropylene, acetal resins, fluoropolymers, polyacrylates, and polysulfones.
The first type bristles and any other bristles utilized ~JDC-375 within this invention may be structured, flocked or coated on their surface area. The first type bristles and any other bristles utilized in this invention may contain additi've's such as, but not limited to abrasives s and polishing agents; anti-cavity agents such as sodium fluoride; antimicrobial agents, and combinations thereof.
In the first embodiment of the invention, it is Zo preferred that 'the first type bristles (3) all have the same free length. As used herein, the term "free length" means the length of the bristle from inner surface (9) of the toothbrush head to the free end of the bristle. The space between the exterior surfaces of i5 adjacent first type bristles (4) and the diameter of the first type bristles may be varied such that a first type bristle packing density of from 50 per cmz to 1000 per cm2 is obtained. Each first type bristle (3) is individually embedded in the head of the toothbrush (2).
2o The first type bristles (3) as well as any other bristles utilized herein may be secured to the toothbrush head (2) by any process known in the art, including those mentioned hereinabove, or by a bonding method wherein an adhesive is utilized to attach the 25 bristles to the toothbrush head.
A combination of first type bristle diameters ranging from about 0.25 mm to about 0.60 mm, and spacing between immediately adjacent bristles ranging from about 0.5 times to about 10 times, preferably about 0.5 times to about 4 times, the diameter of the first type bristles (3) or any other bristles utilized in this invention may s be utilized t=o provide different sensations for different parts of the mouth. For example, the first type bristles (3) may be arranged such that at least one section of the toothbrush head (2) contains first type bristles (3) having diameters ranging from about 0.35 mm to to about 0.60 rnm, while at least one other section of the toothbrush head (2) contains first type bristles (3) having diameters ranging from about 0.25 mm to about 0.35 mm.
is The toothbrush may further include at least one dense tuft (8) of bristles. The skilled art worker will recognize that dense tuft (8) of bristles may be secured to the toothbrush head (2) by means known in the art, such as, but: not limited to, fusion or stapling 2o techniques. The bristles in this tuft may have diameters ranging from about 0.08 mm to about 0.40 mm and a free length ranging from about 7 mm to about 15 mm. The dense tuft (8) of bristles may be arranged anywhere on the' toothbrush head (2). Preferably, the 25 dense tuft (8) of bristles is distal to the toothbrush handle (1). Preferably, when the dense tuft (8) is distal to the toothbrush handle, the dense tuft has a longer length than that of the bristles comprising the toothbrush.
In a second embodiment of the present invention, the toothbrush comprises: a handle; a toothbrush head distal to the handle; at least one second type bristle having a diameter of from about 0.08 mm to about 0.35 mm and a free length of.from about 7 mm to about 16 mm; and at least one third type bristle having a diameter of from to about 0.15 mm to about 0.40 mm and a free length of from about 5 mm to about 14 mm; wherein the trim difference between the second type bristle and the third type bristle ranges from about 0.5 mm to about 3 mm. This toothbrush is believed to provide enhanced cleaning i5 performance .
The second type. of bristle (5) must have a diameter which is sufficiently large to provide the bristle with enough inherent stiffness to be able to remove plaque, 2o food debris, E~tc. from the teeth while remaining flexible enough to follow the contour of the oral surfaces during use. For this purpose, the second type of bristle (5) may have a diameter of from about 0.08 mm to about 0.35 mm, preferably from about 0.13 mm to about 25 0.35 mm, and a free length of from about 7 mm to about 16 mm, preferably from about 9 mm to about 14 mm. The second type bristles (5) may serve the purpose ;.f interdental and subgingival cleaning.
~JDC - 3 7 5 The third type of bristle (6) may serve the purpose of cleaning the surfaces of the teeth. The third type of bristle (6) may have a diameter of from about 0.15 mm to about 0.40 mm, preferably from about 0.20 mm to about s 0.40 mm and a free length of from about 5 mm to about 14 mm, preferably from about 7 mm to about 12 mm. A
trim difference of from about 0.5 mm to about 3 mm is recommended between the free lengths of the second type (5) and third type (6) of bristles to ensure optimal io cleaning interdentally and subgingivally. As used herein, the term "trim difference" means the difference in free lengths between different types of bristles.
The free lengths of the bristles within a given section i5 of the toothbrush may be varied to also provide an improved perception of cleaning via visual and tactile stimuli. For example, a sawtooth cut or a zigzag cut reinforces the consumer's perception of interdental cleaning. Other patterns, such as but not limited to, 2o waves, arcs, etc. , can be used in place of the sawtooth cut or zigzag cut .
In one embodiment of the present invention, alternating sections of second type (5) and third type (6) bristles 25 are contained in the toothbrush to enhance interproximal cleaning efficacy. In this embodiment, second type :gristles (5), which may have a diameter of from about O.Of3 mm to abour_ 0.35 mm, preferably from about 0.13 mm to about 0.35 mm, and a free length of from about 7 mm to about 16 mm, preferably from about 9 mm to about 14 mm, may be <alternated with third type bristles (6), which may have a diameter of from about s 0.15 mm to about: 0.40 mm, preferably from about 0.20 mm to about 0.40 mrn, and a free length of from about 5 mm to about 14 mm, preferably from about 7 mm to about 12 mm. The first sections contain second type bristles, and the second sections contain third type bristles.
io The sections may be from 1 to 7 rows deep. If each section is spaced at 2.15 times the diameter of each adjacent bristle' and the transition is spaced at 2.15 times the average diameter of the adjoining bristles, the density of: the third type bristle section may be i5 380-600 bristles per square centimeter while the density of the second type bristle section may be 100-350 bristles per square centimeter. The lower density of bristles is preferred since it allows for the use of thicker diameter bristles, which provide more cleaning 2o sensation to the consumer.
Other patterns besides alternating rows may also be used for the varying length and diameter bristles and these include, but are not limited to alternating waves, a 25 circle of lon<~er bristles surrounding the shorter bristles along a row, a hexagon of longer bristles surrounding a ~h.orter bristlE, e:.c.
~JDC-375 In another embodiment of the present invention, at least one of a fourth type of bristle (7) is contained in at least one section about the periphery of the toothbrush head (2). As used herein, by "periphery" is meant the s outer edge of the upper surface of the toothbrush head.
Elastomeric material such as, but not limited to rubber may be particularly suited as the material of construction for the fourth type of bristle. The fourth type bristles (7) may be of a diameter of from about io 0.15 mm to about 1.0 mm, preferably about 0.30 mm to about 0.50 mm, and a free length of from about 9 mm to about 15 mm, preferably from about 10 mm to about 13 mm.
In a preferred embodiment, a plurality of fourth type bristles (7) are arranged about the periphery of the i5 toothbrush head. The free length of the fourth type bristles (7) may also alternate along the periphery of the toothbrush head, resulting in forms. Possible forms include, but are. not limited to an arc shape, a sawtooth shape, or a wave shape. Combinations of these height 2o patterns are possible as well, as are repeating patterns, such as a series of smaller arcs along the periphery or a ~;awtooth with an arcing midline.
The present invention may also provide a toothbrush z5 having a multiplicity of bristle diameters and bristle spacing (4) within the toothbrush head (2) to provide different sensations for different parts of tr.2 mouth.
Depending or. the ratio of the: different bristles used of each diameter, and the spacing (4) used between bristles, the bristle density on the toothbrush head (2) can be varied from 50 to 1000 per square centimeter.
The bristle density could also vary along various s regions of the toothbrush head (2) such that one area may have a different bristle density than that of another area t.o provide the customer with desired tactile perception and visual cues.
to The toothbrush may further include at least one dense tuft (8) of bri~;tles. The bristles in the tuft may have diameters ranging from about 0.08 mm to about 0.40 mm and a free length ranging from about 7 mm to about 15 mm. The dense tuft (8) of bristles may be arranged 15 anywhere on the toothbrush head (2). In one embodiment, the toothbrush includes at least one dense tuft with first type bristles; second type bristles; third type bristles; fourth type bristles; or combinations thereof.
The dense tuft or tufts may be of any shape. In top 2o plan, the dense tuft or tufts may be, for example, in the form of a circle, square, oval, triangle, elongated rectangle, polygonal, half-moon, horseshoe, bar, stars, arc and combinations thereof. Preferably, a dense tuft (8) of bristles is located at the tip of the free end of 25 the brush head of the toothbrush to aid in cleaning the posterior teeth.
~JDC-375 In a preferred embodiment, the present invention provides a toothbrush wherein the toothbrush head (2) contains second type bristles (5) which may have a diameter of from about 0.08 mm to about 0.35 mm, preferably from about 0.13 mm to about 0.35 mm, and a free length of from about 7 mm to about 16 mm, preferably from about 9 mm to about 14 mm throughout the toothbrush head (2; third type bristles (6) which may have a diameter of from about 0.15 mm to about 0.40 mm, ~~o preferably from about 0.20 mm to about 0.40 mm, and a free length of from about 5 mm to about 14 mm, preferably from about 7 mm to about 12 mm; and fourth type bristles (';~) having a diameter of from about 0.15 mm to about 1.0 mm, preferably about 0.30 mm to about L5 0.50 mm, and a Eree length of from about 9 mm to about mm, preferably about 10 mm to about 13 mm along the periphery of the toothbrush head (2). The toothbrush head contains a periphery and a distal end. At the distal end of the toothbrush head (2) is a dense tuft :zo (8) of bristles for cleaning of the back teeth and gums.
The bristles in the dense tuft (8) may have diameters ranging f rom about 0 . 0 8 mm to about 0 . 4 0 mm and a free length ranging from about 7 mm to about 15 mm. With the varying bristle patterns within this toothbrush, z5 consumers receive not. only a superior cleaning of their entire oral cavity (teeth surfaces, gums, interproximal regions, etc.) but also are able to perceive the better ~JDC-375 clean through sensual cues (visual and tactile) delivered via the bristle configuration.
Brief Description of the Drawings Descriptions of the Drawing Figures follow. The descriptions are intended to illustrate various aspects of the invention, but should not be construed as limiting the scope of the invention.
io Figure 1 displays a toothbrush having a handle (1) and a toothbrush head (2) distal to the toothbrush handle. A
multiplicity of first type bristles (3) of uniform length and diameter are embedded in the toothbrush head i5 (2). The first. type bristles (3) are mutually spaced apart from one another by a distance (4) from 0.5 times to 10 times the diameter of the bristles.
Figure 1A is a top plan view of the toothbrush shown in 2o Figure 1.
Figure 2 displays a toothbrush having second type bristles (5) and third type bristles (6) embedded in the toothbrush head (2). The bristles are mutually spaced z5 apart from one another by a distance (4) from 0.5 times to 10 times the' diameter of the bristles. The second type bristles (5) are arranged in hexugorc,l shapes around the third type bristles (6).
~JDC - 3 7 5 Figure 3 displays a toothbrush having alternating rows of second type bristles (5) and third type bristles (6) embedded in the toothbrush head (2). The bristles are mutually spaced apart from one another by a distance (4) s from o.5 times to to times the diameter of the bristles.
Figure 3A is a top plan view of the toothbrush shown in Figure 3.
io Figure 4 displays a toothbrush having alternating rows of second type bristles (5) and third type bristles (6) embedded in the toothbrush head (2). The bristles are mutually spaced (4) apart from one another by a distance from 0.5 times t.o 10 times the diameter of the bristles.
i5 Along the periphery of the toothbrush head (2) are fourth type br:i~;tles (7) embedded in the toothbrush head (2) .
Figure 4A is a top plan view of the toothbrush shown in 2o Figure 4.
Figure 5 displays a toothbrush having second type bristles (5) and third type bristles (6) embedded in the toothbrush head (2). The bristles are mutually spaced 25 apart from one another by a distance (4) from 0.5 times to 10 times the diameter of the bristles. The second type bristles (5) are arranged in hexagonal shapes around ~he third type bristles (6). At the end of the ~JDC-375 toothbrush head ( 2 ) di stal to the handle ( 1 ) , is a dense tuft of bristles (8) .
Figure 5A is a top view of the toothbrush shown in s Figure 5.
Figure 6 displays a toothbrush having second type bristles (5) and third type bristles (6) embedded in the toothbrush head (2). The bristles are mutually spaced to apart from one another by a distance (4) from 0.5 times to 10 times the diameter of the bristles. The second type bristles (5) are arranged :in hexagonal shapes around the third type bristles (6). At the end of the toothbrush head (2) distal to the handle (1) , is a dense i5 tuft of bristle=s (8). Along the periphery of the toothbrush head (2) are fourth type bristles (7) embedded ~.n the toothbrush head (2).
Figure 6A is a top view of the toothbrush shown in zo Figure 6.
Figure 7 displays a toothbrush having alternating rows of second type bristles (5) and third type bristles (6) embedded in the toothbrush head (2). The bristles are 25 mutually spaced apart from one another by a distance (4) from 0.5 times to 10 times the diameter of the bristles.
At the end of the too:hbrush head (2) distal to the handle (1), is a dense tuft of bristles (8). Along the ,7DC-375 periphery of the toothbrush head (2) are fourth type bristles (7) embedded in the toothbrush head (2).
Figure 7A is a top view of the toothbrush shown in Figure 7.
Figure 8 displays a toothbrush having randomly distributed second type bristles (5) and third type bristles (6) embedded in the toothbrush head (2). The bristles are mutually spaced apart from one another by a io distance (4) from 0.5 times to 10 times the diameter of the bristles. At the end of the toothbrush head (2) distal to the handle (1), is a dense tuft of bristles (8). Along the periphery of the toothbrush head (2) are fourth type bri:~tles (7) embedded in the toothbrush head is (2) .
Figure 8A is a top view of the toothbrush shown in Figure 8.
2o Figure 9 displays a perspective view of a toothbrush having a multiplicity of individually embedded first type bristles (:3) and a multiplicity of dense tufts (8) of bristles embedded in the toothbrush head (2).
zs Figure 9A is a top plan view of the toothbrush shown in Figure 9.
Figures 10 and 11 are perspective views of different embodiments of a toothbrush having a multiplicity of individually embedded first type bristles (3) and a multiplicity of dense tufts (8) of bristles embedded in s the toothbrush head ( 2 ) .
Figures 10A a:nd 11A are top plan views of the toothbrushes she>wn in Figures 10 and 11, respectively.
to Several example; of the invention are set forth below to further illustrate the nature of the invention and the manner of carrying it out. However, the invention should not be considered as being limited to the details thereof.
Example 1 A toothbrush wa:~ made according to the design shown in Figure 8. The bristles of the toothbrush according to 2o Figure 8 had t:he following diameters: second type bristles (5): 0.18 mm; third type bristles (6): 0.23 mm; fourth type bristles (7); 0.2 mm; and dense tuft of bristles (8): 0.25 mm. The heights of the bristles were as follows: second type bristles: 9-10 mm; third type bristles: 10.5 mm; fourth type bristles: 10-11.25 mm; and dense tuft of bristles: 12.5 mm. The space between the exterior adjacent surfaces of the second type bristles (~~) was about 0.021 -nm; the corresponding space between the exterior surfaces of the third type bristles (6) was about 0.0197 mm; the space between the exterior adjacent surfaces of the fourth type bristles (7) was about 0.018 mm; and the space between the s exterior surface: of the individual bristles comprising the dense tuft (8) of bristles was about 0.020 mm.
Two toothbrushes were made according to the design shown in Figure 11. First toothbrush (Sample 11A) had bristles of the :Following diameters: first type bristles (3): 0.20 mm; dense tufts (8) of bristles throughout the toothbrush head: 0.20 mm; and distal dense tuft (8):
of bristles 0.20 mm. The heights of the bristles were as follows: first t,irpe bristles (3) : 11 mm; dense tufts of ~_s bristles throughout the toothbrush head: 9 mm; and distal dense tuft (8) of bristles 12.5 mm. Second toothbrush (Samp:le 11B) had the following bristle diameters: first type bristles (3): 0.20 mm; dense tufts (8) of bristles throughout the toothbrush head:
20 0.18 mm; and distal dense tuft (8): of bristles 0.20 mm. The heights of the bristles were as follows: first type bristles (3): 11 mm; dense tufts (8) of bristles throughout the toothbrush head: 9 mm; and distal dense tuft (8) of bristles: 12.5 mm. In each sample 11A, 11H, the first type bristles (3) were individually embedded in toothbrush head 2.
~DC-375 The above-described three toothbrushes were tested for efficacy at cleaning between the teeth according to the procedure described in "Access to interproximal tooth surfaces by diff~=_rent bristle designs and stiffnesses of toothbrushes", Nygaard-Ostby et al., Scand. J. Dent Res.
1979, 87, 424-430, the disclosure of which is incorporated herein by reference. The results of the tests are reported in Table 1.
_.o Table 1.
Sample Between Teeth Access (mm) Figure 8 J.2 11A 11.8 11B 12.6 Oral B Cross Action 10.8 Oral B Indicator 7.7 The data above demonstrates that the toothbrushes according to the present invention clean between the teeth better than commercially available toothbrushes.
:L 5 Example 2 The efficacy of the toothbrush of Figure 8 and the Oral B* Indicator toothbrush was tested by a clinical trial.
zo An examiner-blind, randomized, crossover clinical study was conducted with seventy healthy adults. Plaque was evaluated before and after brushing for one minute using ~rDC-375 the Rustogi Modification of the Navy Plaque Index ("RMNPI"). Subjects were randomly assigned to use one of the two test. toothbrushes, namely the Oral B*
Indicator toothbrush or the toothbrush made according to the design shown in Figure 8. After brushing at the initial visit, the subjects returned two weeks later to repeat the procedure with the other of the two test toothbrushes. Evaluation of plaque using RMNPI was done at both visits. RMNPI scores were given for the whole to mouth, interproximal sites, marginal sites, behind the last molar, anterior sites, and posterior sites. The change in plaque from pre-brushing to post brushing was compared for both toothbrushes. The results are shown in Table 2.
Table 2 Plague Scores Invention* Oral B Indicator Tooth Site Pre Post delta Pre Post I delta Whole Mouth 0.64 0.30 52.8 0.64 0.36 44.1 Marginal 1 0.63 37.1 1 0.71 28.9 Interproximal 1 0.38 61.9 1 0.47 52.9 Last Molar 0.58 0.23 60 0.57 0.31 45.8 Anterior 0.65 0.30 54 0.65 0.34 48 Posterio~ 0.64 0.31 51.8 0.64 0.38 40.7 *Toothbrush of Figure 8.
The scores reported are the mean scores for the groups of participants. The term "delta" is the percent reduction in plaque for each group from before brushing to after brushing. Using statistical techniques, it was s concluded that the toothbrush of the invention removed significantly more plaque than a commercially available toothbrush from the whole mouth, gingival margin, interproximal surface, and behind the last molar, respectively 20%, 28%, 17%, and 31% more.
~. o Toothbrushes in accordance with the present invention provide efficient tooth cleaning, are easily cleaned, and dry in a rel<~tively short period of time.
vDC-375
Claims (25)
1. A toothbrush comprising:
a handle;
a toothbrush head distal to the handle; and a multiplicity of first type bristles, each of said bristles having a diameter ranging from about 0.25 mm to about 0.60 mm and being individually embedded in said toothbrush head; said bristles being mutually spaced apart from one another by a distance ranging from about 0.5 times to about 10 times the diameter of the bristles.
a handle;
a toothbrush head distal to the handle; and a multiplicity of first type bristles, each of said bristles having a diameter ranging from about 0.25 mm to about 0.60 mm and being individually embedded in said toothbrush head; said bristles being mutually spaced apart from one another by a distance ranging from about 0.5 times to about 10 times the diameter of the bristles.
2. A toothbrush according to Claim 1 further comprising at least one dense tuft of bristles.
3. A toothbrush according to Claim 1 wherein:
the first type bristles comprise at least one bristle having a diameter from about 0.35 mm to about 0.60 mm and at least one bristle having a diameter of from about 0.25 mm to about 0.35 mm.
the first type bristles comprise at least one bristle having a diameter from about 0.35 mm to about 0.60 mm and at least one bristle having a diameter of from about 0.25 mm to about 0.35 mm.
4. A toothbrush according to Claim 3 wherein the toothbrush head further comprises sections wherein:
the bristles are arranged such that at least one section of the toothbrush head contains bristles having diameters from about 0.35 mm to about 0.60 mm, while at least one section of the toothbrush head contains first type bristles having diameters ranging from about 0.25 mm to about 0.35 mm.
the bristles are arranged such that at least one section of the toothbrush head contains bristles having diameters from about 0.35 mm to about 0.60 mm, while at least one section of the toothbrush head contains first type bristles having diameters ranging from about 0.25 mm to about 0.35 mm.
5. A toothbrush comprising:
a handle;
a toothbrush head distal to the handle;
at least one individually embedded second type bristle having a diameter of from about 0.08 mm to about 0.35 mm and a free length of from about 7 mm to about 16 mm; and at least one third type bristle having a diameter of from about 0.15 mm to about 0.40 mm and a free length of from about 5 mm to about 14 mm; wherein the trim difference between the second type bristle and the third type bristle ranges from about 0.5 mm to about 3 mm.
a handle;
a toothbrush head distal to the handle;
at least one individually embedded second type bristle having a diameter of from about 0.08 mm to about 0.35 mm and a free length of from about 7 mm to about 16 mm; and at least one third type bristle having a diameter of from about 0.15 mm to about 0.40 mm and a free length of from about 5 mm to about 14 mm; wherein the trim difference between the second type bristle and the third type bristle ranges from about 0.5 mm to about 3 mm.
6. A toothbrush according to Claim 5 further comprising at least one section wherein:
the free lengths of the bristles within at least one section of the toothbrush head are varied such as to create a sawtooth cut profile.
the free lengths of the bristles within at least one section of the toothbrush head are varied such as to create a sawtooth cut profile.
7. A toothbrush according to Claim 5 further comprising at least one section wherein:
the free lengths of the bristles within at least one section of the toothbrush head are varied such as to create a wave cut profile.
the free lengths of the bristles within at least one section of the toothbrush head are varied such as to create a wave cut profile.
8. A toothbrush according to Claim 5 further comprising at least one section wherein:
the free lengths of the bristles within at least one section of the toothbrush head are varied such as to create an arc cut profile.
the free lengths of the bristles within at least one section of the toothbrush head are varied such as to create an arc cut profile.
9. A toothbrush according to Claim 5 further comprising first sections and second sections wherein:
the first sections comprise second type bristles and the second sections comprise third type bristles and each of the first and second sections comprises from 1 to 7 rows of bristles.
the first sections comprise second type bristles and the second sections comprise third type bristles and each of the first and second sections comprises from 1 to 7 rows of bristles.
10. The toothbrush according to Claim 9 wherein:
the first sections are alternately spaced with the second sections.
the first sections are alternately spaced with the second sections.
11. A toothbrush according to Claim 5 wherein:
the second and third type bristles are arranged to create an alternating wave pattern.
the second and third type bristles are arranged to create an alternating wave pattern.
12. A toothbrush according to Claim 5 wherein:
the second and third type bristles are arranged to create a pattern of a circle of second type bristles surrounding the third type bristles along a row.
the second and third type bristles are arranged to create a pattern of a circle of second type bristles surrounding the third type bristles along a row.
13. A toothbrush according to Claim 5 wherein:
the second and third type bristles are arranged to create a pattern of a hexagon of second type bristles surrounding a third type bristle.
the second and third type bristles are arranged to create a pattern of a hexagon of second type bristles surrounding a third type bristle.
14. A toothbrush according to Claim 5 further comprising:
at least one fourth type bristle having a diameter of from about 0.15 mm to about 1.0 mm and a free length of from about 9 mm to about 15 mm arranged about the periphery of the toothbrush head.
at least one fourth type bristle having a diameter of from about 0.15 mm to about 1.0 mm and a free length of from about 9 mm to about 15 mm arranged about the periphery of the toothbrush head.
15. A toothbrush according to Claim 14 wherein:
the toothbrush contains a plurality of fourth type bristles arranged along the periphery of the toothbrush head; and the height of the fourth type bristles alternates along the periphery of the toothbrush head to create an arc shaped form.
the toothbrush contains a plurality of fourth type bristles arranged along the periphery of the toothbrush head; and the height of the fourth type bristles alternates along the periphery of the toothbrush head to create an arc shaped form.
16. A toothbrush according to Claim 14 wherein:
the toothbrush contains a plurality of fourth type bristles arranged along the periphery of the toothbrush head; and the height of the fourth type bristles alternates along the periphery of the toothbrush head to create a sawtooth shaped form.
the toothbrush contains a plurality of fourth type bristles arranged along the periphery of the toothbrush head; and the height of the fourth type bristles alternates along the periphery of the toothbrush head to create a sawtooth shaped form.
17. A toothbrush according to Claim 14 wherein:
the toothbrush contains a plurality of fourth type bristles arranged along the periphery of the toothbrush head; and the height of the fourth type bristles alternates along the periphery of the toothbrush head to create a wave shaped form.
the toothbrush contains a plurality of fourth type bristles arranged along the periphery of the toothbrush head; and the height of the fourth type bristles alternates along the periphery of the toothbrush head to create a wave shaped form.
18. A toothbrush according to Claim 5 wherein:
the toothbrush contains a multiplicity of bristle diameters within the toothbrush head.
the toothbrush contains a multiplicity of bristle diameters within the toothbrush head.
19. A toothbrush according to Claim 5 wherein:
the toothbrush contains a multiplicity of bristle spacing within the toothbrush head.
the toothbrush contains a multiplicity of bristle spacing within the toothbrush head.
20. A toothbrush according to Claim 5 further comprising:
at least one dense tuft of bristles.
at least one dense tuft of bristles.
21. A toothbrush comprising:
a handle;
a toothbrush head distal to the handle, the toothbrush head comprising a periphery and a distal end; and bristles which are individually embedded in the toothbrush head and mutually spaced apart from one another by a distance from about 0.5 times to about 10 times the diameter of the bristles;
wherein the bristles comprise second type bristles having a diameter of from about 0.08 mm to about 0.35 mm and a free length of from about 7 mm to about 16 mm;
third type bristles having a diameter of from about 0.15 mm to about 0.40 mm and a free length of from about 5 mm to 14 mm; fourth type bristles having a diameter of from about 0.15 mm to about 1.0 mm and a free length of from about 9 mm to about 15 mm arranged along the periphery of the toothbrush head; and a dense tuft of bristles at the distal end.
a handle;
a toothbrush head distal to the handle, the toothbrush head comprising a periphery and a distal end; and bristles which are individually embedded in the toothbrush head and mutually spaced apart from one another by a distance from about 0.5 times to about 10 times the diameter of the bristles;
wherein the bristles comprise second type bristles having a diameter of from about 0.08 mm to about 0.35 mm and a free length of from about 7 mm to about 16 mm;
third type bristles having a diameter of from about 0.15 mm to about 0.40 mm and a free length of from about 5 mm to 14 mm; fourth type bristles having a diameter of from about 0.15 mm to about 1.0 mm and a free length of from about 9 mm to about 15 mm arranged along the periphery of the toothbrush head; and a dense tuft of bristles at the distal end.
22. A toothbrush comprising:
a handle;
a toothbrush head distal to the handle;
a multiplicity of first type bristles, each of said bristles having a diameter ranging from about 0.25 mm to about 0.60 mm and being individually embedded in said toothbrush head; said bristles being mutually spaced apart from one another by a distance ranging from about 0.5 times to about 10 times the diameter of the bristles; and at least one dense tuft of bristles.
a handle;
a toothbrush head distal to the handle;
a multiplicity of first type bristles, each of said bristles having a diameter ranging from about 0.25 mm to about 0.60 mm and being individually embedded in said toothbrush head; said bristles being mutually spaced apart from one another by a distance ranging from about 0.5 times to about 10 times the diameter of the bristles; and at least one dense tuft of bristles.
23. A toothbrush according to Claim 22 wherein:
the first type bristles comprise at least one bristle having a diameter from about 0.35 mm to about 0.60 mm and at least one bristle having a diameter of from about 0.25 mm to about 0.35 mm.
the first type bristles comprise at least one bristle having a diameter from about 0.35 mm to about 0.60 mm and at least one bristle having a diameter of from about 0.25 mm to about 0.35 mm.
24. A toothbrush according to Claim 22 wherein the dense tuft of bristles has a shape selected from the group consisting of circle, square, oval, triangle, elongated rectangle, polygonal, half-moon, horseshoe, bar, stars, arc and combinations thereof.
25. The toothbrush according to Claim 24 further comprising a distal dense tuft, of bristles.
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US09/863,773 US20020004964A1 (en) | 1999-12-15 | 2001-05-23 | Toothbrush with individually embedded bristles |
US09/863,773 | 2001-05-23 |
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CA2386572A1 true CA2386572A1 (en) | 2002-11-23 |
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CA002386572A Abandoned CA2386572A1 (en) | 2001-05-23 | 2002-05-15 | A toothbrush with individually embedded bristles |
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JP (1) | JP2003009948A (en) |
CN (1) | CN100512713C (en) |
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CA (1) | CA2386572A1 (en) |
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-
2001
- 2001-05-23 US US09/863,773 patent/US20020004964A1/en not_active Abandoned
-
2002
- 2002-05-15 CA CA002386572A patent/CA2386572A1/en not_active Abandoned
- 2002-05-16 AU AU40682/02A patent/AU4068202A/en not_active Abandoned
- 2002-05-17 CO CO02042325A patent/CO5360638A1/en not_active Application Discontinuation
- 2002-05-22 JP JP2002148195A patent/JP2003009948A/en active Pending
- 2002-05-22 BR BR0201916-7A patent/BR0201916A/en not_active IP Right Cessation
- 2002-05-23 CN CNB021204551A patent/CN100512713C/en not_active Expired - Fee Related
- 2002-05-23 GB GB0211826A patent/GB2375705B/en not_active Expired - Fee Related
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GB2375705A (en) | 2002-11-27 |
GB0211826D0 (en) | 2002-07-03 |
JP2003009948A (en) | 2003-01-14 |
GB2375705B (en) | 2005-01-12 |
US20020004964A1 (en) | 2002-01-17 |
CN1386456A (en) | 2002-12-25 |
AU4068202A (en) | 2002-11-28 |
BR0201916A (en) | 2003-04-22 |
CO5360638A1 (en) | 2004-01-30 |
CN100512713C (en) | 2009-07-15 |
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Legal Events
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FZDE | Discontinued |