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CA2223277A1 - Procede de detection d'un anticorps contre la deuxieme glycoproteine d'enveloppe du virus de l'hepatite c - Google Patents

Procede de detection d'un anticorps contre la deuxieme glycoproteine d'enveloppe du virus de l'hepatite c Download PDF

Info

Publication number
CA2223277A1
CA2223277A1 CA 2223277 CA2223277A CA2223277A1 CA 2223277 A1 CA2223277 A1 CA 2223277A1 CA 2223277 CA2223277 CA 2223277 CA 2223277 A CA2223277 A CA 2223277A CA 2223277 A1 CA2223277 A1 CA 2223277A1
Authority
CA
Canada
Prior art keywords
hcv
antigen
antibody
dna sequence
specific binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2223277
Other languages
English (en)
Inventor
Gregory F. Okasinski
Verlyn G. Schaefer
Thomas S. Suhar
Richard R. Lesniewski
James W. Scheffel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2223277A1 publication Critical patent/CA2223277A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Procédé de détection d'un anticorps contre le virus de l'hépatite C dansun échantillon de test. Le procédé consiste en particulier à utiliser une protéine de recombinaison qui est le produit d'expression de cellules mammifères transformées par un vecteur d'expression hétérologue comprenant une séquence d'ADN codant une protéinetronquée E2. On décrit également des matériels de test contenant cette protéine de recombinaison.
CA 2223277 1995-06-07 1996-06-04 Procede de detection d'un anticorps contre la deuxieme glycoproteine d'enveloppe du virus de l'hepatite c Abandoned CA2223277A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48101895A 1995-06-07 1995-06-07
US08/481,018 1995-06-07

Publications (1)

Publication Number Publication Date
CA2223277A1 true CA2223277A1 (fr) 1996-12-19

Family

ID=23910252

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2223277 Abandoned CA2223277A1 (fr) 1995-06-07 1996-06-04 Procede de detection d'un anticorps contre la deuxieme glycoproteine d'enveloppe du virus de l'hepatite c

Country Status (4)

Country Link
EP (1) EP0836708A1 (fr)
JP (1) JPH11507129A (fr)
CA (1) CA2223277A1 (fr)
WO (1) WO1996041196A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4335099A (en) * 1998-06-18 2000-01-05 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Surface targeted expression of a modified hepatitis c virus envelope protein
CN102081093A (zh) * 2009-11-30 2011-06-01 武汉大学 一种丙型肝炎病毒及其表面抗原的试剂盒及检测方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991019515A1 (fr) * 1990-06-21 1991-12-26 The Board Of Trustees Of The Leland Stanford Junior University Mutant du domaine constant d'immunoglobulines oligomeres presentant une activite cytolytique accrue a mediation de complement
AU2679492A (en) * 1991-09-16 1993-04-27 Abbott Laboratories Hepatitis c assay
UA39944C2 (uk) * 1992-07-07 2001-07-16 Чірон Корпорейшн Спосіб визначення ранньої сероконверсії у ссавця-хазяїна до вірусу гепатиту с і набір для використання в способі
US5610009A (en) * 1994-01-28 1997-03-11 Abbott Laboratories Mammalian expression systems for hepatitis C virus envelope genes
WO1996004301A2 (fr) * 1994-07-29 1996-02-15 Chiron Corporation Nouveaux polypeptides a troncature e1 et e2 de l'hepatite c et procede d'obtention de ces derniers

Also Published As

Publication number Publication date
WO1996041196A1 (fr) 1996-12-19
JPH11507129A (ja) 1999-06-22
EP0836708A1 (fr) 1998-04-22

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