CA2252038A1 - Buccal polar spray or capsule - Google Patents
Buccal polar spray or capsuleInfo
- Publication number
- CA2252038A1 CA2252038A1 CA002252038A CA2252038A CA2252038A1 CA 2252038 A1 CA2252038 A1 CA 2252038A1 CA 002252038 A CA002252038 A CA 002252038A CA 2252038 A CA2252038 A CA 2252038A CA 2252038 A1 CA2252038 A1 CA 2252038A1
- Authority
- CA
- Canada
- Prior art keywords
- capsule
- polar solvent
- invention comprises
- buccal
- flavoring agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007921 spray Substances 0.000 title abstract 3
- 239000002775 capsule Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000002798 polar solvent Substances 0.000 abstract 3
- 239000000443 aerosol Substances 0.000 abstract 2
- 239000000796 flavoring agent Substances 0.000 abstract 2
- 235000013355 food flavoring agent Nutrition 0.000 abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 1
- 239000003995 emulsifying agent Substances 0.000 abstract 1
- 239000007903 gelatin capsule Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000002200 mouth mucosa Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Medicinal Preparation (AREA)
Abstract
A buccal aerosol spray or capsule using a polar solvent has now been developed which provides biologically active compounds for rapid absorption through the oral mucosa, resulting in fast onset of effect.
The buccal aerosol spray of the invention comprises: polar solvent 75-99,8 % compound 0.0025-40 %, flavoring agent 0.05-5 %. The soft bite gelatin capsule of the invention comprises as comprising as fill composition: polar solvent 50-99,8 %, emulsifier 0-20 %, active compound 0.0003-26 %, and flavoring agent 0.05-60 %.
The buccal aerosol spray of the invention comprises: polar solvent 75-99,8 % compound 0.0025-40 %, flavoring agent 0.05-5 %. The soft bite gelatin capsule of the invention comprises as comprising as fill composition: polar solvent 50-99,8 %, emulsifier 0-20 %, active compound 0.0003-26 %, and flavoring agent 0.05-60 %.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63006596A | 1996-04-12 | 1996-04-12 | |
| US08/630,065 | 1996-04-12 | ||
| PCT/US1997/002793 WO1997038662A2 (en) | 1996-04-12 | 1997-02-21 | Buccal polar spray or capsule |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2252038A1 true CA2252038A1 (en) | 1997-10-23 |
| CA2252038C CA2252038C (en) | 2006-10-10 |
Family
ID=37114287
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002252038A Expired - Fee Related CA2252038C (en) | 1996-04-12 | 1997-02-21 | Buccal polar spray or capsule |
Country Status (1)
| Country | Link |
|---|---|
| CA (1) | CA2252038C (en) |
-
1997
- 1997-02-21 CA CA002252038A patent/CA2252038C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2252038C (en) | 2006-10-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20170221 |