CA2126819A1 - Trousse et methode de preciblage - Google Patents
Trousse et methode de preciblageInfo
- Publication number
- CA2126819A1 CA2126819A1 CA002126819A CA2126819A CA2126819A1 CA 2126819 A1 CA2126819 A1 CA 2126819A1 CA 002126819 A CA002126819 A CA 002126819A CA 2126819 A CA2126819 A CA 2126819A CA 2126819 A1 CA2126819 A1 CA 2126819A1
- Authority
- CA
- Canada
- Prior art keywords
- antibody
- ligand
- effector moiety
- epitope
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6891—Pre-targeting systems involving an antibody for targeting specific cells
- A61K47/6897—Pre-targeting systems with two or three steps using antibody conjugates; Ligand-antiligand therapies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Optics & Photonics (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP93202016 | 1993-07-09 | ||
EP93202016.7 | 1993-07-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2126819A1 true CA2126819A1 (fr) | 1995-01-10 |
Family
ID=8213969
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002126819A Abandoned CA2126819A1 (fr) | 1993-07-09 | 1994-06-27 | Trousse et methode de preciblage |
Country Status (6)
Country | Link |
---|---|
JP (1) | JPH07181186A (fr) |
KR (1) | KR960014510A (fr) |
AU (1) | AU678474B2 (fr) |
CA (1) | CA2126819A1 (fr) |
FI (1) | FI943269A (fr) |
ZA (1) | ZA944893B (fr) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0628077B1 (fr) * | 1992-12-10 | 2002-03-20 | Celltech Therapeutics Limited | Anticorps humanises diriges contre l'antigene a33 |
-
1994
- 1994-06-27 CA CA002126819A patent/CA2126819A1/fr not_active Abandoned
- 1994-07-06 ZA ZA944893A patent/ZA944893B/xx unknown
- 1994-07-08 JP JP6157499A patent/JPH07181186A/ja not_active Expired - Lifetime
- 1994-07-08 AU AU67360/94A patent/AU678474B2/en not_active Ceased
- 1994-07-08 FI FI943269A patent/FI943269A/fi unknown
- 1994-07-08 KR KR1019940016440A patent/KR960014510A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU678474B2 (en) | 1997-05-29 |
JPH07181186A (ja) | 1995-07-21 |
FI943269A0 (fi) | 1994-07-08 |
AU6736094A (en) | 1995-01-19 |
KR960014510A (ko) | 1996-05-22 |
FI943269A (fi) | 1995-01-10 |
ZA944893B (en) | 1995-02-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Dead |