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CA2186601A1 - New combination of a .beta.-receptor blocker and a local anaesthetic - Google Patents

New combination of a .beta.-receptor blocker and a local anaesthetic

Info

Publication number
CA2186601A1
CA2186601A1 CA002186601A CA2186601A CA2186601A1 CA 2186601 A1 CA2186601 A1 CA 2186601A1 CA 002186601 A CA002186601 A CA 002186601A CA 2186601 A CA2186601 A CA 2186601A CA 2186601 A1 CA2186601 A1 CA 2186601A1
Authority
CA
Canada
Prior art keywords
beta
receptor blocker
new combination
local anaesthetic
selective
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002186601A
Other languages
French (fr)
Other versions
CA2186601C (en
Inventor
Arne Torsten Eek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9401174A external-priority patent/SE9401174D0/en
Application filed by Individual filed Critical Individual
Publication of CA2186601A1 publication Critical patent/CA2186601A1/en
Application granted granted Critical
Publication of CA2186601C publication Critical patent/CA2186601C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

New combination of a .beta.-receptor blocker, an enantiomer thereof, and a local anaesthetic, administered simultaneously or sequentially, giving excellent pain relief. Also comprised in the invention is the use of a non-selective .beta.-receptor blocker alone, especially a non-selective .beta.-receptor blocker giving pain relief.
CA002186601A 1994-04-07 1995-03-24 New combination of a .beta.-receptor blocker and a local anaesthetic Expired - Fee Related CA2186601C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9401174-9 1994-04-07
SE9401174A SE9401174D0 (en) 1994-04-07 1994-04-07 New combination
PCT/SE1995/000314 WO1995027511A1 (en) 1994-04-07 1995-03-24 NEW COMBINATION OF A β-RECEPTOR BLOCKER AND A LOCAL ANAESTHETIC

Publications (2)

Publication Number Publication Date
CA2186601A1 true CA2186601A1 (en) 1995-10-19
CA2186601C CA2186601C (en) 2007-04-03

Family

ID=37951693

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002186601A Expired - Fee Related CA2186601C (en) 1994-04-07 1995-03-24 New combination of a .beta.-receptor blocker and a local anaesthetic

Country Status (1)

Country Link
CA (1) CA2186601C (en)

Also Published As

Publication number Publication date
CA2186601C (en) 2007-04-03

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed