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CA2174081A1 - Membrane protein polypeptide having function of supporting pre-b cell growth and gene therefor - Google Patents

Membrane protein polypeptide having function of supporting pre-b cell growth and gene therefor

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Publication number
CA2174081A1
CA2174081A1 CA002174081A CA2174081A CA2174081A1 CA 2174081 A1 CA2174081 A1 CA 2174081A1 CA 002174081 A CA002174081 A CA 002174081A CA 2174081 A CA2174081 A CA 2174081A CA 2174081 A1 CA2174081 A1 CA 2174081A1
Authority
CA
Canada
Prior art keywords
membrane protein
protein polypeptide
cell growth
novel membrane
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002174081A
Other languages
French (fr)
Other versions
CA2174081C (en
Inventor
Toshio Hirano
Tsuneyasu Kaisho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority claimed from PCT/JP1994/001732 external-priority patent/WO1995010536A1/en
Publication of CA2174081A1 publication Critical patent/CA2174081A1/en
Application granted granted Critical
Publication of CA2174081C publication Critical patent/CA2174081C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Abstract

A gene encoding a novel membrane protein polypeptide having pre-B cell growth-supporting ability, and a novel membrane protein polypeptide consisting of 180 amino acid residues having pre-B cell growth-supporting ability or a part of it. A method for producing said novel membrane protein polypeptide by preparing transformants by transforming a host cell with a vector containing said gene and culturing said transformants. A monoclonal antibody recognizing said novel membrane protein polypeptide.
The above gene encodes the membrane protein having pre-B cell growth-supporting ability. The homogeneous and purified novel membrane protein polypeptide can be produced in large quantities and in addition, monoclonal antibodies recognizing said polypeptide can be produced; thus it becomes possible to identify rheumatoid arthritis (RA) and also prepare reagents for the clinical diagnosis thereof.
CA002174081A 1993-10-15 1994-10-14 Membrane protein polypeptide having function of supporting pre-b cell growth and gene therefor Expired - Lifetime CA2174081C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP28162293 1993-10-15
JP5/281622 1993-10-15
PCT/JP1994/001732 WO1995010536A1 (en) 1993-10-15 1994-10-14 Membrane protein polypeptide having function of supporting pre-b cell growth and gene therefor

Publications (2)

Publication Number Publication Date
CA2174081A1 true CA2174081A1 (en) 1995-04-20
CA2174081C CA2174081C (en) 2005-11-22

Family

ID=35474753

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002174081A Expired - Lifetime CA2174081C (en) 1993-10-15 1994-10-14 Membrane protein polypeptide having function of supporting pre-b cell growth and gene therefor

Country Status (1)

Country Link
CA (1) CA2174081C (en)

Also Published As

Publication number Publication date
CA2174081C (en) 2005-11-22

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Effective date: 20141014