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CA2158482A1 - UCF1 Compounds, Derivatives Thereof and Processes for Their Preparation - Google Patents

UCF1 Compounds, Derivatives Thereof and Processes for Their Preparation

Info

Publication number
CA2158482A1
CA2158482A1 CA 2158482 CA2158482A CA2158482A1 CA 2158482 A1 CA2158482 A1 CA 2158482A1 CA 2158482 CA2158482 CA 2158482 CA 2158482 A CA2158482 A CA 2158482A CA 2158482 A1 CA2158482 A1 CA 2158482A1
Authority
CA
Canada
Prior art keywords
compounds
ucf1
derivatives
see
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2158482
Other languages
French (fr)
Other versions
CA2158482C (en
Inventor
Hirofumi Nakano
Mitsunobu Hara
Yutaka Saito
Yoji Ikuina
Toshimitsu Takiguchi
Masami Okabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2120640A external-priority patent/JP2854671B2/en
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority claimed from CA002041237A external-priority patent/CA2041237C/en
Publication of CA2158482A1 publication Critical patent/CA2158482A1/en
Application granted granted Critical
Publication of CA2158482C publication Critical patent/CA2158482C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compounds UCF1 and derivatives thereof exhibit anti-bacterial and anti-tumour activities and may be used for the preparation of anti-bacterial and anti-tumour agents.
Compounds UCF1 may be produced by fermentation of a microorganism of the genus Streptomyces capable of producing compounds UCF1, preferably Streptomyces sp.
UOF1 (FERM BP-2844) and recovering the desired compounds from the cultured broth.
The compounds UCF1 have the formula (see fig. I) (I) [wherein R represents either (see fig. II) or (see fig. III) The compounds may be oxidised to obtain derivatives of formula (see fig. IV) which exhibit similar pharmacological activities.
CA002158482A 1990-05-10 1991-04-25 Ucf1 compounds, derivatives thereof and processes for their preparation Expired - Fee Related CA2158482C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP2120640A JP2854671B2 (en) 1990-05-10 1990-05-10 New substance UCF1
JP120,640/90 1990-05-10
JP320,439/90 1990-11-22
JP32043990 1990-11-22
CA002041237A CA2041237C (en) 1990-05-10 1991-04-25 Ucf1 compounds derivatives thereof and processes for their preparation

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002041237A Division CA2041237C (en) 1990-05-10 1991-04-25 Ucf1 compounds derivatives thereof and processes for their preparation

Publications (2)

Publication Number Publication Date
CA2158482A1 true CA2158482A1 (en) 1991-11-11
CA2158482C CA2158482C (en) 1997-10-07

Family

ID=27168898

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002158482A Expired - Fee Related CA2158482C (en) 1990-05-10 1991-04-25 Ucf1 compounds, derivatives thereof and processes for their preparation

Country Status (1)

Country Link
CA (1) CA2158482C (en)

Also Published As

Publication number Publication date
CA2158482C (en) 1997-10-07

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