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CA2027814A1 - Traitement d'une maladie hepatobiliaire a base de composes 5-cetoprostaglandin - Google Patents

Traitement d'une maladie hepatobiliaire a base de composes 5-cetoprostaglandin

Info

Publication number
CA2027814A1
CA2027814A1 CA2027814A CA2027814A CA2027814A1 CA 2027814 A1 CA2027814 A1 CA 2027814A1 CA 2027814 A CA2027814 A CA 2027814A CA 2027814 A CA2027814 A CA 2027814A CA 2027814 A1 CA2027814 A1 CA 2027814A1
Authority
CA
Canada
Prior art keywords
treatment
keto
hepatobiliary disease
prostaglandin compounds
hepatobiliary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2027814A
Other languages
English (en)
Other versions
CA2027814C (fr
Inventor
Ryuji Ueno
Hiroyoshi Osama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sucampo GmbH
Original Assignee
Ueno Seiyaku Oyo Kenkyujo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ueno Seiyaku Oyo Kenkyujo KK filed Critical Ueno Seiyaku Oyo Kenkyujo KK
Publication of CA2027814A1 publication Critical patent/CA2027814A1/fr
Application granted granted Critical
Publication of CA2027814C publication Critical patent/CA2027814C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002027814A 1989-10-20 1990-10-17 Traitement d'une maladie hepatobiliaire a base de composes 5-cetoprostaglandin Expired - Lifetime CA2027814C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP27460689 1989-10-20
JP274606/1989 1989-10-20

Publications (2)

Publication Number Publication Date
CA2027814A1 true CA2027814A1 (fr) 1991-04-21
CA2027814C CA2027814C (fr) 1996-07-30

Family

ID=17544076

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002027814A Expired - Lifetime CA2027814C (fr) 1989-10-20 1990-10-17 Traitement d'une maladie hepatobiliaire a base de composes 5-cetoprostaglandin

Country Status (10)

Country Link
US (1) US5096927A (fr)
EP (1) EP0424156B1 (fr)
JP (1) JPH03204816A (fr)
KR (1) KR0127297B1 (fr)
AT (1) ATE132749T1 (fr)
CA (1) CA2027814C (fr)
DE (1) DE69024744T2 (fr)
DK (1) DK0424156T3 (fr)
ES (1) ES2085898T3 (fr)
GR (1) GR3018674T3 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE174221T1 (de) * 1990-05-01 1998-12-15 R Tech Ueno Ltd Behandlung von pankreaskrankheit mit 15-keto- prostaglandin e-derivaten
CA2150287C (fr) 1994-06-03 2004-08-10 Ryuji Ueno Agent therapeutique pour les affections hepatobiliaires
CA2274670C (fr) * 1997-10-13 2011-04-12 R-Tech Ueno, Ltd. 15-ceto prostaglandines en tant qu'inhibiteurs de l'hypertension portale
AU739343B2 (en) * 1997-11-28 2001-10-11 Sucampo Ag Endothelin antagonist
TWI225398B (en) * 1999-07-14 2004-12-21 R Tech Ueno Ltd Composition for treatment of external secretion disorders
CN1241570C (zh) * 2000-04-06 2006-02-15 苏坎波公司 胆汁分泌促进组合物
TWI302100B (en) * 2001-05-02 2008-10-21 Sucampo Ag Composition for treating drug-induced constipation
AR037524A1 (es) * 2001-11-14 2004-11-17 Sucampo Ag Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion
US7732487B2 (en) 2001-11-19 2010-06-08 Sucampo Ag Method for treating a disease or condition responsive to opening of C1C-2 channel
US20080207759A1 (en) * 2007-02-27 2008-08-28 Sucampo Ag Method for protecting mitochondria
US20090082442A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched lubiprostone

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4374856A (en) * 1980-09-10 1983-02-22 The Upjohn Company Liver cytoprotection using PGE's
FR2517679A1 (fr) * 1981-12-03 1983-06-10 Synthelabo Derives de diaza-3,7a cyclohepta (j,k) fluorenes, leur preparation et leur application en therapeutique
JPS58164512A (ja) * 1982-03-25 1983-09-29 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物を有効成分として含有する肝臓疾患治療剤
DE3401542A1 (de) * 1984-01-18 1985-08-01 Merck Patent Gmbh, 6100 Darmstadt Schwefelhaltige 6-ketoprostaglandine
EP0153858A3 (fr) * 1984-02-29 1985-12-11 The Upjohn Company Application thérapeutique de prostaglandines
JPS62277352A (ja) * 1986-01-30 1987-12-02 Ono Pharmaceut Co Ltd 新規な6−ケト−プロスタグランジンe1誘導体、それらの製造方法およびそれらを有効成分として含有する細胞障害治療剤
CA1323364C (fr) * 1987-01-28 1993-10-19 Ryuzo Ueno Prostaglandines e et agents anti-ulcereux contenant celles-ci
CA1322749C (fr) * 1987-01-28 1993-10-05 Ryuzo Ueno Prostaglandines de la serie d, et tranquilisants et soporifiques en contenant
CA1324129C (fr) * 1987-04-30 1993-11-09 Ryuzo Ueno Prostaglandines de la serie f
DE3869471D1 (de) * 1987-05-15 1992-04-30 Ueno Seiyaku Oyo Kenkyujo Kk Fiebersteigende zusammensetzung.
DE3876050T2 (de) * 1987-09-18 1993-03-25 Ueno Seiyaku Oyo Kenkyujo Kk Okulare hypotensivagenzien.
GB2210556B (en) * 1987-10-02 1991-07-17 Ueno Seiyaku Oyo Kenkyujo Kk The use of 15-keto-16-halo-prostaglandins in cathartic compositions
JP2597629B2 (ja) * 1988-02-26 1997-04-09 株式会社 上野製薬応用研究所 13,14−ジヒドロ−15−ケトプロスタグランジン類の安定化
JP2597649B2 (ja) * 1988-05-11 1997-04-09 株式会社上野製薬応用研究所 気管・気管支拡張剤
AU619543B2 (en) * 1988-05-11 1992-01-30 Sucampo Ag Use of 15-ketoprostaglandin e or f compounds for uterine contraction
JPH03101622A (ja) * 1989-09-11 1991-04-26 Green Cross Corp:The 肝炎予防治療剤

Also Published As

Publication number Publication date
CA2027814C (fr) 1996-07-30
ATE132749T1 (de) 1996-01-15
KR910007531A (ko) 1991-05-30
ES2085898T3 (es) 1996-06-16
EP0424156A3 (en) 1992-04-22
DK0424156T3 (da) 1996-02-05
US5096927A (en) 1992-03-17
EP0424156A2 (fr) 1991-04-24
EP0424156B1 (fr) 1996-01-10
GR3018674T3 (en) 1996-04-30
DE69024744D1 (de) 1996-02-22
JPH0571568B2 (fr) 1993-10-07
DE69024744T2 (de) 1996-05-23
KR0127297B1 (ko) 1998-04-01
JPH03204816A (ja) 1991-09-06

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