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CA2069956A1 - Process for the production of 17-oxosteroids - Google Patents

Process for the production of 17-oxosteroids

Info

Publication number
CA2069956A1
CA2069956A1 CA002069956A CA2069956A CA2069956A1 CA 2069956 A1 CA2069956 A1 CA 2069956A1 CA 002069956 A CA002069956 A CA 002069956A CA 2069956 A CA2069956 A CA 2069956A CA 2069956 A1 CA2069956 A1 CA 2069956A1
Authority
CA
Canada
Prior art keywords
nrrl
mycobacterium
oxosteroids
production
spec
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002069956A
Other languages
French (fr)
Other versions
CA2069956C (en
Inventor
Alfred Weber
Mario Kennecke
Uwe Klages
Klaus Nickisch
Ralph Rohde
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2069956A1 publication Critical patent/CA2069956A1/en
Application granted granted Critical
Publication of CA2069956C publication Critical patent/CA2069956C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/12—Acting on D ring
    • C12P33/16—Acting at 17 position

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Excavating Of Shafts Or Tunnels (AREA)
  • Record Information Processing For Printing (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
  • Oscillators With Electromechanical Resonators (AREA)

Abstract

A process for the production of 17-oxosteroids by fermentative oxidation of 17.beta.-hydroxy steroids is described, which is characterized in that for the fermentation, a bacterial culture of the species Mycobacterium spec. NRRL B-3805, Mycobacterium spec. NRRL B-3683, Mycobacterium phlei NRRL B-8154 or Mycobacterium fortuitum NRRL B-8153 is used.
CA002069956A 1990-08-18 1991-08-01 Process for the production of 17-oxosteroids Expired - Fee Related CA2069956C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4026462 1990-08-18
DEP4026462.9 1990-08-18
PCT/DE1991/000628 WO1992003572A1 (en) 1990-08-18 1991-08-01 Method of preparing 17-oxosteroids

Publications (2)

Publication Number Publication Date
CA2069956A1 true CA2069956A1 (en) 1992-02-19
CA2069956C CA2069956C (en) 2001-05-08

Family

ID=6412643

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002069956A Expired - Fee Related CA2069956C (en) 1990-08-18 1991-08-01 Process for the production of 17-oxosteroids

Country Status (15)

Country Link
EP (1) EP0496846B1 (en)
JP (1) JP3137645B2 (en)
AT (1) ATE152773T1 (en)
AU (1) AU650467B2 (en)
CA (1) CA2069956C (en)
CZ (1) CZ279575B6 (en)
DE (1) DE59108700D1 (en)
DK (1) DK0496846T3 (en)
ES (1) ES2103818T3 (en)
FI (1) FI102973B (en)
GR (1) GR3024188T3 (en)
HU (1) HU213017B (en)
RU (1) RU2082762C1 (en)
SK (1) SK279666B6 (en)
WO (1) WO1992003572A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7335650B2 (en) 2000-01-14 2008-02-26 Sterix Limited Composition
US6593321B2 (en) * 2001-06-11 2003-07-15 Southwest Foundation For Biomedical Research 2-alkoxyestradiol analogs with antiproliferative and antimitotic activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3386890A (en) * 1965-07-12 1968-06-04 American Home Prod Process for preparing equilin
ES533260A0 (en) * 1983-06-15 1985-02-01 Schering Ag PROCEDURE FOR THE PREPARATION OF 13A-ALQUILGONANOS
DE3876769T2 (en) * 1987-12-23 1993-06-09 Roussel Uclaf MICROBIOLOGICAL PRODUCTION OF 9-ALPHA-HYDROXY-17-KETO-STEROIDS.

Also Published As

Publication number Publication date
ATE152773T1 (en) 1997-05-15
SK279666B6 (en) 1999-02-11
JP3137645B2 (en) 2001-02-26
CZ279575B6 (en) 1995-05-17
EP0496846A1 (en) 1992-08-05
FI102973B1 (en) 1999-03-31
GR3024188T3 (en) 1997-10-31
EP0496846B1 (en) 1997-05-07
ES2103818T3 (en) 1997-10-01
AU650467B2 (en) 1994-06-23
HU213017B (en) 1997-01-28
FI921697A0 (en) 1992-04-15
FI102973B (en) 1999-03-31
DE59108700D1 (en) 1997-06-12
RU2082762C1 (en) 1997-06-27
AU8228491A (en) 1992-03-17
CA2069956C (en) 2001-05-08
WO1992003572A1 (en) 1992-03-05
HUT64603A (en) 1994-01-28
DK0496846T3 (en) 1997-12-01
HU9201646D0 (en) 1992-08-28
JPH05503218A (en) 1993-06-03
CS254991A3 (en) 1992-02-19

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Legal Events

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