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CA1025450A - 1,4-dihydropyridine esters - Google Patents

1,4-dihydropyridine esters

Info

Publication number
CA1025450A
CA1025450A CA204,204A CA204204A CA1025450A CA 1025450 A CA1025450 A CA 1025450A CA 204204 A CA204204 A CA 204204A CA 1025450 A CA1025450 A CA 1025450A
Authority
CA
Canada
Prior art keywords
dihydropyridine esters
dihydropyridine
esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA204,204A
Other languages
French (fr)
Other versions
CA204204S (en
Inventor
Wulf Vater
Kurt Stoepel
Friedrich Bossert
Egbert Wehinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of CA1025450A publication Critical patent/CA1025450A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
CA204,204A 1973-07-12 1974-07-05 1,4-dihydropyridine esters Expired CA1025450A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732335466 DE2335466A1 (en) 1973-07-12 1973-07-12 ALCOXY ALKYL-1,4-DIHYDROPYRIDINE, THE METHOD FOR THEIR MANUFACTURING AND THEIR USE AS A MEDICINAL PRODUCT

Publications (1)

Publication Number Publication Date
CA1025450A true CA1025450A (en) 1978-01-31

Family

ID=5886689

Family Applications (1)

Application Number Title Priority Date Filing Date
CA204,204A Expired CA1025450A (en) 1973-07-12 1974-07-05 1,4-dihydropyridine esters

Country Status (21)

Country Link
JP (3) JPS6011030B2 (en)
AT (1) AT337699B (en)
AU (1) AU477107B2 (en)
BE (1) BE817540A (en)
CA (1) CA1025450A (en)
CH (2) CH614196A5 (en)
DD (1) DD118631A5 (en)
DE (1) DE2335466A1 (en)
DK (1) DK373974A (en)
ES (5) ES428185A1 (en)
FI (1) FI212074A (en)
FR (1) FR2236497B1 (en)
GB (1) GB1436289A (en)
HU (1) HU171401B (en)
IE (1) IE39602B1 (en)
IL (1) IL45233A (en)
LU (1) LU70498A1 (en)
NL (1) NL7409344A (en)
PL (2) PL94266B1 (en)
SE (1) SE7409146L (en)
ZA (1) ZA744461B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552911A (en) * 1975-07-02 1979-09-19 Fujisawa Pharmaceutical Co 1,4 dihydropyridine derivatives and the preparation thereof
GB1591089A (en) * 1976-12-17 1981-06-10 Fujisawa Pharmaceutical Co 1,4-dihydropyridine derivatives and process for preparation thereof
JPS53146941U (en) * 1977-04-26 1978-11-18
DE3222367A1 (en) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Use of 1,4-dihydropyridines in antiarteriosclerotics and preparation thereof
DE3312216A1 (en) * 1983-04-05 1984-10-11 Bayer Ag, 5090 Leverkusen METHOD FOR PRODUCING SYMMETRIC 1,4-DIHYDROPYRIDINE CARBONIC ACID ESTERS
DE3312283A1 (en) * 1983-04-05 1984-10-18 Bayer Ag, 5090 Leverkusen METHOD FOR PRODUCING UNBALANCED 1,4-DIHYDROPYRIDINE CARBONIC ACID ESTERS
DE3432563A1 (en) * 1984-09-05 1986-03-13 Bayer Ag, 5090 Leverkusen NEW PYRIDYLETHYL DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN MEDICINAL PRODUCTS
GB8428552D0 (en) * 1984-11-12 1984-12-19 Sandoz Ltd Organic compounds
US4678796A (en) * 1984-11-30 1987-07-07 Warner-Lambert Company 2-alkylidene derivatives of 1,2,3,4-tetrahydropyridine-2,5-pyridine carboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
CA1267416A (en) 1985-06-17 1990-04-03 Ila Sircar 1,4-dihydropyridine derivatives useful for the treatment of cardiovascular disorders
US4732898A (en) * 1986-04-29 1988-03-22 Warner-Lambert Company 2-(2-aryl-2-oxoalkylidene) analogs of-3,5-pyridinedicarboxylic acid dialkyl esters useful for treatment of cardiovascular disorders
JPS6378289A (en) * 1986-09-20 1988-04-08 株式会社富士通ゼネラル Number detector for vehicle
AT400241B (en) * 1988-03-08 1995-11-27 Egyt Gyogyszervegyeszeti Gyar Process for the preparation of a 1,4-dihydropyridine derivative
AT399873B (en) * 1988-03-08 1995-08-25 Egyt Gyogyszervegyeszeti Gyar Process for the preparation of a 1,4-dihydropyridine derivative
GR1002248B (en) * 1988-03-08 1996-04-23 Egyt Gyogyszervegyeszeti Gyar 1,4-dihydropyridine derivatives preparation method
AT399872B (en) * 1988-03-08 1995-08-25 Egyt Gyogyszervegyeszeti Gyar Prodn. of 1,4-di:hydro-pyridine deriv. - by reacting new 2-nitro-benzylidne-amine cpds. with methyl actoacetate, used for treating hypertension
FR2672890A1 (en) * 1991-02-20 1992-08-21 Inst Investigacion Desarrol 2,6-DIMETHYL-4- (4'-HYDROXY-3 ', 5'-DI-T-BUTYLPHENYL) -1,4-DIHYDROPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS SENSORS OF FREE RADICALS.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1923990C3 (en) * 1969-05-10 1978-11-23 Bayer Ag Process for the preparation of N-substituted M-dihydropyridine-S.S-dicarboxylic acid esters

Also Published As

Publication number Publication date
PL91873B1 (en) 1977-03-31
JPS57131763A (en) 1982-08-14
DK373974A (en) 1975-03-03
FR2236497A1 (en) 1975-02-07
ES428185A1 (en) 1976-12-16
JPS6011030B2 (en) 1985-03-22
ZA744461B (en) 1975-07-30
ES448394A1 (en) 1977-07-16
ES448396A1 (en) 1977-09-16
HU171401B (en) 1978-01-28
JPS57131764A (en) 1982-08-14
JPS5040578A (en) 1975-04-14
JPS5943951B2 (en) 1984-10-25
ATA569674A (en) 1976-11-15
AU477107B2 (en) 1976-10-14
DD118631A5 (en) 1976-03-12
BE817540A (en) 1975-01-13
NL7409344A (en) 1975-01-14
PL94266B1 (en) 1977-07-30
AT337699B (en) 1977-07-11
IE39602B1 (en) 1978-11-22
GB1436289A (en) 1976-05-19
IL45233A (en) 1978-06-15
CH622507A5 (en) 1981-04-15
JPS5943952B2 (en) 1984-10-25
IL45233A0 (en) 1974-10-22
SE7409146L (en) 1975-01-13
IE39602L (en) 1975-01-12
ES448397A1 (en) 1977-08-01
FI212074A (en) 1975-01-13
FR2236497B1 (en) 1978-07-21
LU70498A1 (en) 1975-03-27
ES448395A1 (en) 1977-09-16
DE2335466A1 (en) 1975-01-30
CH614196A5 (en) 1979-11-15
AU7096974A (en) 1976-01-08

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