BRPI1012113A2 - identificação de micro-rnas envolvidos na remodelação pós-infarto do miocárdio e insuficiência cardíada - Google Patents

identificação de micro-rnas envolvidos na remodelação pós-infarto do miocárdio e insuficiência cardíada

Info

Publication number: BRPI1012113A2
Authority: BR; Brazil
Prior art keywords: micro; post; identification; heart failure; myocardial infarction
Prior art date: 2009-05-20

Application number

BRPI1012113A

Other languages

English (en)

Inventor

Eric N Olson

Eva Van Rooij

Original Assignee

Univ Texas

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-05-20

Filing date

2010-05-20

Publication date

2016-03-29

2010-05-20 Application filed by Univ Texas filed Critical Univ Texas

2016-03-29 Publication of BRPI1012113A2 publication Critical patent/BRPI1012113A2/pt

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

BRPI1012113A 2009-05-20 2010-05-20 identificação de micro-rnas envolvidos na remodelação pós-infarto do miocárdio e insuficiência cardíada BRPI1012113A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US17977509P	2009-05-20	2009-05-20
PCT/US2010/035642 WO2010135570A1 (en)	2009-05-20	2010-05-20	Identification of micro-rnas involved in post-myocardial infarction remodeling and heart failure

Publications (1)

Publication Number	Publication Date
BRPI1012113A2 true BRPI1012113A2 (pt)	2016-03-29

Family

ID=43126512

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI1012113A BRPI1012113A2 (pt)	2009-05-20	2010-05-20	identificação de micro-rnas envolvidos na remodelação pós-infarto do miocárdio e insuficiência cardíada

Country Status (12)

Country	Link
US (1)	US9072765B2 (pt)
EP (1)	EP2437750A4 (pt)
JP (1)	JP2012527478A (pt)
KR (1)	KR20120047214A (pt)
CN (1)	CN102481310A (pt)
AU (1)	AU2010249482A1 (pt)
BR (1)	BRPI1012113A2 (pt)
CA (1)	CA2763156A1 (pt)
MX (1)	MX2011012418A (pt)
NZ (1)	NZ596971A (pt)
RU (1)	RU2011151991A (pt)
WO (1)	WO2010135570A1 (pt)

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CN102453757B (zh) *	2010-10-22	2014-02-12	中国科学院动物研究所	一种微小rna及其反义核酸在诊断、预防、治疗和/或预后评估心肌缺血性损伤中的用途
US8871731B2 (en) *	2011-03-16	2014-10-28	Migagen Therapeutics, Inc.	Micro-RNA for the regulation of cardiac apoptosis and contractile function
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US10662234B2 (en)	2011-06-07	2020-05-26	Mesoblast International Sàrl	Methods for repairing tissue damage using protease-resistant mutants of stromal cell derived factor-1
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WO2013060894A1 (en) *	2011-10-27	2013-05-02	INSERM (Institut National de la Santé et de la Recherche Médicale)	Methods for the treatment and diagnosis of atherosclerosis
CN102416184A (zh) *	2011-12-08	2012-04-18	哈尔滨医科大学	microRNA-1的反义锁核苷酸序列在制备预防或治疗心肌梗死后心衰药物中的应用
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CN103293318B (zh) *	2013-05-22	2014-10-29	吉林大学	利用地高辛标记EDC交联桥连法检测miRNAs方法
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CN104667295A (zh) *	2013-11-30	2015-06-03	复旦大学	miR-30家族抑制剂在制备防治急性心肌梗死药物中的用途
JP6878274B2 (ja)	2014-10-03	2021-05-26	シーダーズ−サイナイ・メディカル・センターＣｅｄａｒｓ−ＳｉｎａｉＭｅｄｉｃａｌＣｅｎｔｅｒ	筋ジストロフィーの処置における心筋球由来細胞およびこのような細胞によって分泌されたエキソソーム
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EP3138914A1 (en) *	2015-09-01	2017-03-08	Universiteit Maastricht	Micrornas for the treatment of heart diseases
US10119139B2 (en)	2015-09-14	2018-11-06	Vanderbilt University	Treatment for conditions associated with fibrosis and collagen deposition
EP3402543B1 (en)	2016-01-11	2021-09-08	Cedars-Sinai Medical Center	Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction
CN105695612A (zh) *	2016-04-19	2016-06-22	中南大学	microRNA-126-5p在心肌损伤中的表达检测方法
WO2017210652A1 (en)	2016-06-03	2017-12-07	Cedars-Sinai Medical Center	Cdc-derived exosomes for treatment of ventricular tachyarrythmias
CA3031071A1 (en)	2016-07-18	2018-01-25	Jaan Biotherapeutics, Llc	Compositions and methods for treatment of cardiac diseases
WO2018041726A1 (en) *	2016-08-27	2018-03-08	Academisch Medisch Centrum	Biomarkers for determining the presence of an unstable atherosclerotic plaque
EP3515459A4 (en)	2016-09-20	2020-08-05	Cedars-Sinai Medical Center	CELLS DERIVED FROM CARDIOSPHERES AND THEIR EXTRACELLULAR VESICLES TO DELAY OR REVERSE AGING AND AGE-RELATED DISORDERS
US11246883B2 (en) *	2016-09-30	2022-02-15	Academia Sinica	Microrna let-7 and transforming growth factor beta receptor III axis as target for cardiac injuries
WO2018183127A1 (en) *	2017-03-25	2018-10-04	MiRagen Therapeutics, Inc.	Mir-92 inhibitors for treatment of heart failure
EP3612191A4 (en)	2017-04-19	2020-12-30	Cedars-Sinai Medical Center	METHODS AND COMPOSITIONS FOR TREATING SKELETAL MUSCLE DYSTROPHY
CN107312836A (zh) *	2017-06-22	2017-11-03	深圳大学	小分子RNAmiRNA‑146a‑5p在相关疾病风险诊断中的应用
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CN107460241B (zh) *	2017-08-09	2020-05-19	深圳承启生物科技有限公司	外泌体小分子rna在急性心肌梗死风险评估中的应用
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2010
- 2010-05-20 BR BRPI1012113A patent/BRPI1012113A2/pt not_active IP Right Cessation
- 2010-05-20 CN CN2010800330590A patent/CN102481310A/zh active Pending
- 2010-05-20 JP JP2012512044A patent/JP2012527478A/ja active Pending
- 2010-05-20 MX MX2011012418A patent/MX2011012418A/es not_active Application Discontinuation
- 2010-05-20 NZ NZ596971A patent/NZ596971A/en not_active IP Right Cessation
- 2010-05-20 AU AU2010249482A patent/AU2010249482A1/en not_active Abandoned
- 2010-05-20 EP EP10778408.4A patent/EP2437750A4/en not_active Withdrawn
- 2010-05-20 WO PCT/US2010/035642 patent/WO2010135570A1/en active Application Filing
- 2010-05-20 RU RU2011151991/15A patent/RU2011151991A/ru not_active Application Discontinuation
- 2010-05-20 CA CA2763156A patent/CA2763156A1/en not_active Abandoned
- 2010-05-20 US US13/321,756 patent/US9072765B2/en active Active
- 2010-05-20 KR KR1020117030345A patent/KR20120047214A/ko not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO2010135570A1 (en)	2010-11-25
US9072765B2 (en)	2015-07-07
NZ596971A (en)	2013-12-20
US20120165392A1 (en)	2012-06-28
CN102481310A (zh)	2012-05-30
EP2437750A1 (en)	2012-04-11
AU2010249482A1 (en)	2012-01-12
RU2011151991A (ru)	2013-06-27
EP2437750A4 (en)	2014-11-05
KR20120047214A (ko)	2012-05-11
CA2763156A1 (en)	2010-11-25
MX2011012418A (es)	2012-07-20
JP2012527478A (ja)	2012-11-08

Publication	Publication Date	Title
BRPI1012113A2 (pt)	2016-03-29	identificação de micro-rnas envolvidos na remodelação pós-infarto do miocárdio e insuficiência cardíada
SMT201600075B (it)	2016-04-29	Composto di diamminocarbossammide eterociclica
BR112012001480A2 (pt)	2015-09-01	Diferenciação de células-tronco embriônicas humanas
DOP2012000114A (es)	2012-08-15	Inhibidor bromodominio de benzodiazepina
BR112012005146A2 (pt)	2018-01-23	fotobiorreator
DK2617392T3 (da)	2015-02-16	Protese med overflader med forskellige teksturer
DOP2011000397A (es)	2012-07-15	Nuevos derivados de fenilimidazol como inhibidores de la enzima pde10a
FI20095529A0 (fi)	2009-05-12	Probioottien uusi käyttö
BRPI0913925A2 (pt)	2015-08-04	Diferenciação de células-tronco pluripotentes
BR112012007260A2 (pt)	2019-09-24	garrafa de água
BR112012005371A2 (pt)	2016-03-29	desmontagem de componentes interligados
UY33155A (es)	2011-07-29	Indolil-piperidinil bencilaminas como inhibidores de beta-triptasa
DK2453858T3 (da)	2014-11-03	Fremgangsmåde
BRPI1009018A2 (pt)	2015-12-01	fotobiorreator
IT1398296B1 (it)	2013-02-22	Disposizione di sensori
FI20096402A0 (fi)	2009-12-28	Veriryhmästatuksen käyttö II
FI20095464A (fi)	2010-10-28	Puhdistusmenetelmä ja puhdistuslaite
FI20096281A0 (fi)	2009-12-03	Telirakenne
BRPI1010026A2 (pt)	2019-09-24	biossensor para medir biomaterial
FR2952663B1 (fr)	2011-12-23	Profiles de maintien mecanique et recouvrement des modules
IT1394232B1 (it)	2012-06-01	Apparato di manipolazione di contenitori
FR2936998B1 (fr)	2014-05-02	Longeron de bogie
UY33136A (es)	2011-07-29	Tropinonabencilaminas como inhibidores de la beta-triptasa
FR2944196B1 (fr)	2016-01-01	Montant de rayonnage renforce
DE102009007956A8 (de)	2011-05-05	Umrichter

Legal Events

Date	Code	Title	Description
2016-09-20	B08F	Application fees: application dismissed [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 5A E 6A ANUIDADES.
2017-01-10	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.