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BRPI1007994A2 - metabólitos análogos de ceramida - Google Patents

metabólitos análogos de ceramida

Info

Publication number
BRPI1007994A2
BRPI1007994A2 BRPI1007994A BRPI1007994A BRPI1007994A2 BR PI1007994 A2 BRPI1007994 A2 BR PI1007994A2 BR PI1007994 A BRPI1007994 A BR PI1007994A BR PI1007994 A BRPI1007994 A BR PI1007994A BR PI1007994 A2 BRPI1007994 A2 BR PI1007994A2
Authority
BR
Brazil
Prior art keywords
ceramide analog
analog metabolites
metabolites
ceramide
analog
Prior art date
Application number
BRPI1007994A
Other languages
English (en)
Inventor
Sayer Claudia
Jordine Guido
Zollinger Markus
Brinkmann Volker
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI1007994A2 publication Critical patent/BRPI1007994A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Transplantation (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BRPI1007994A 2009-02-24 2010-02-23 metabólitos análogos de ceramida BRPI1007994A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP09153550 2009-02-24
PCT/EP2010/052231 WO2010097371A1 (en) 2009-02-24 2010-02-23 Ceramide-analogous metabolites

Publications (1)

Publication Number Publication Date
BRPI1007994A2 true BRPI1007994A2 (pt) 2018-03-13

Family

ID=40447014

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1007994A BRPI1007994A2 (pt) 2009-02-24 2010-02-23 metabólitos análogos de ceramida

Country Status (14)

Country Link
US (1) US8673982B2 (pt)
EP (1) EP2400960B1 (pt)
JP (1) JP2012518671A (pt)
KR (1) KR20110126631A (pt)
CN (1) CN102333530A (pt)
AU (1) AU2010217605B2 (pt)
BR (1) BRPI1007994A2 (pt)
CA (1) CA2752003A1 (pt)
ES (1) ES2411138T3 (pt)
MX (1) MX2011008876A (pt)
PL (1) PL2400960T3 (pt)
PT (1) PT2400960E (pt)
RU (1) RU2011138963A (pt)
WO (1) WO2010097371A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10391066B2 (en) * 2012-10-19 2019-08-27 Texas Tech University System Compositions and methods for the treatment of Parkinson's disease
WO2014084676A1 (ko) * 2012-11-30 2014-06-05 (주)아모레퍼시픽 신규한 유사 세라마이드 화합물 및 그 제조방법
RU2663833C2 (ru) * 2013-03-05 2018-08-10 Биокон Лимитед Способ получения соединений 2-амино-1,3-пропандиола и их солей
KR101510683B1 (ko) * 2013-09-03 2015-04-10 (주)네오팜 카나비노이드 수용체에 길항작용을 가지는 신규한 유사 세라마이드 유도체 및 이를 포함하는 약학 또는 화장품 조성물
EP3118621A1 (en) 2015-07-14 2017-01-18 Fundació Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) Methods and compositions for the diagnosis and for the treatment of adrenoleukodystrophy

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5604229A (en) * 1992-10-21 1997-02-18 Yoshitomi Pharmaceutical Industries, Ltd. 2-amino-1,3-propanediol compound and immunosuppressant
WO1996006068A1 (fr) * 1994-08-22 1996-02-29 Yoshitomi Pharmaceutical Industries, Ltd. Compose benzenique et son utilisation medicale
US5948820A (en) * 1994-08-22 1999-09-07 Yoshitomi Pharmaceutical Industries, Ltd. Benzene compound and pharmaceutical use thereof
RU2402324C2 (ru) * 2004-07-30 2010-10-27 Новартис Аг Композиции на основе соединений 2-амино-1,3-пропандиола
GT200600350A (es) * 2005-08-09 2007-03-28 Formulaciones líquidas
EP1961734B1 (en) * 2005-12-15 2011-09-14 Mitsubishi Tanabe Pharma Corporation Amine compound and use thereof for medical purposes
CN101240002B (zh) * 2007-02-07 2011-01-26 首都医科大学 脂肪酰氨基酰阿糖胞苷缀合物、其制备方法和应用

Also Published As

Publication number Publication date
MX2011008876A (es) 2011-09-21
CN102333530A (zh) 2012-01-25
EP2400960A1 (en) 2012-01-04
US20110306672A1 (en) 2011-12-15
PT2400960E (pt) 2013-06-28
AU2010217605B2 (en) 2012-07-26
JP2012518671A (ja) 2012-08-16
ES2411138T3 (es) 2013-07-04
PL2400960T3 (pl) 2013-08-30
WO2010097371A1 (en) 2010-09-02
KR20110126631A (ko) 2011-11-23
AU2010217605A1 (en) 2011-08-18
CA2752003A1 (en) 2010-09-02
EP2400960B1 (en) 2013-04-17
RU2011138963A (ru) 2013-04-10
US8673982B2 (en) 2014-03-18

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A, 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]