BRPI1007414A2 - derivados de tiadiazóis e de oxadiazóis, o respectivo preparo e a respectiva aplicação em terapêutica - Google Patents

derivados de tiadiazóis e de oxadiazóis, o respectivo preparo e a respectiva aplicação em terapêutica

Info

Publication number: BRPI1007414A2
Authority: BR; Brazil
Prior art keywords: therapeutic; thiadiazole; preparation; application; oxadiazole derivatives
Prior art date: 2009-01-28

Application number

BRPI1007414-7A

Other languages

English (en)

Inventor

Fett Eykmar

Mougenot Patrick

Nicolai Eric

Philippo Christophe

Original Assignee

Sanofi

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-01-28

Filing date

2010-01-27

Publication date

2018-03-06

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42261833&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI1007414(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-01-28 Priority claimed from FR0900359A external-priority patent/FR2941457A1/fr

2009-09-01 Priority claimed from FR0904137A external-priority patent/FR2949464B1/fr

2010-01-27 Application filed by Sanofi filed Critical Sanofi

2018-03-06 Publication of BRPI1007414A2 publication Critical patent/BRPI1007414A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- C07D285/135—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Immunology (AREA)
Endocrinology (AREA)
Neurology (AREA)
Virology (AREA)
Emergency Medicine (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Psychiatry (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Child & Adolescent Psychology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Oncology (AREA)
Dermatology (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

BRPI1007414-7A 2009-01-28 2010-01-27 derivados de tiadiazóis e de oxadiazóis, o respectivo preparo e a respectiva aplicação em terapêutica BRPI1007414A2 (pt)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
FR09/00359		2009-01-28
FR0900359A FR2941457A1 (fr)	2009-01-28	2009-01-28	Derives de thiadiazoles et d'oxadiazoles leur preparation et leur application en therapeutique
FR0904137A FR2949464B1 (fr)	2009-09-01	2009-09-01	Derives de thiadiazoles et d'oxadiazoles, leur preparation et leur application en therapeutique
FR09/04137		2009-09-01
PCT/FR2010/050124 WO2010086551A1 (fr)	2009-01-28	2010-01-27	Dérivés de thiadiazoles et d'oxadiazoles, leur préparation et leur application en thérapeutique

Publications (1)

Publication Number	Publication Date
BRPI1007414A2 true BRPI1007414A2 (pt)	2018-03-06

Family

ID=42261833

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI1007414-7A BRPI1007414A2 (pt)	2009-01-28	2010-01-27	derivados de tiadiazóis e de oxadiazóis, o respectivo preparo e a respectiva aplicação em terapêutica

Country Status (26)

Country	Link
US (1)	US8546391B2 (pt)
EP (1)	EP2391611B1 (pt)
JP (1)	JP2012516312A (pt)
KR (1)	KR20110112845A (pt)
CN (1)	CN102365273A (pt)
AR (1)	AR075177A1 (pt)
AU (1)	AU2010209545A1 (pt)
BR (1)	BRPI1007414A2 (pt)
CA (1)	CA2750742A1 (pt)
CL (1)	CL2011001839A1 (pt)
CO (1)	CO6400221A2 (pt)
CR (1)	CR20110403A (pt)
DO (1)	DOP2011000245A (pt)
EA (1)	EA201170983A1 (pt)
EC (1)	ECSP11011224A (pt)
IL (1)	IL214260A0 (pt)
MA (1)	MA33069B1 (pt)
MX (1)	MX2011007991A (pt)
NI (1)	NI201100149A (pt)
NZ (1)	NZ594244A (pt)
PE (1)	PE20120362A1 (pt)
TN (1)	TN2011000353A1 (pt)
TW (1)	TW201031645A (pt)
UY (1)	UY32405A (pt)
WO (1)	WO2010086551A1 (pt)
ZA (1)	ZA201105525B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2963005B1 (fr) *	2010-07-23	2012-08-17	Sanofi Aventis	Derives d'oxadiazoles et de pyridazines, leur preparation et leur application en therapeutique
CN102557941B (zh) *	2010-12-07	2015-04-22	成都睿智化学研究有限公司	一种螺环丙基甲酰衍生物的中间体化合物的制备方法
JP6099753B2 (ja) *	2012-10-03	2017-03-22	アドビナスセラピューティクスリミテッド	スピロ環化合物、その組成物及びその医薬応用
WO2014060381A1 (de) *	2012-10-18	2014-04-24	Bayer Cropscience Ag	Heterocyclische verbindungen als schädlingsbekämpfungsmittel
AU2014352830B2 (en) *	2013-11-21	2018-12-13	Concordia University, Inc.	Substituted (4'-hydroxyphenyl)cycloalkane compounds and uses thereof as selective agonists of the estrogen receptor beta isoform
WO2015106272A1 (en) *	2014-01-13	2015-07-16	Harki Daniel A	Small molecule inhibitors of apobec3g and apobec3b
EP3034500A1 (en)	2014-12-17	2016-06-22	Genkyotex Sa	Amido thiazole derivatives as NADPH oxidase inhibitors
US10532987B2 (en) *	2015-02-17	2020-01-14	Guangzhou Institutes Of Biomedicine And Health, Chinese Academy Of Science	Compounds and methods for inducing browning of white adipose tissue
CN106278895B (zh) *	2015-05-15	2021-07-09	Dic株式会社	羧酸化合物、其制造方法、使用该化合物的液晶组合物
WO2019193540A1 (en) *	2018-04-06	2019-10-10	Glaxosmithkline Intellectual Property Development Limited	Heteroaryl derivatives of formula (i) as atf4 inhibitors
WO2023060573A1 (en) *	2021-10-15	2023-04-20	Beijing Danatlas Pharmaceutical Co., Ltd.	Novel thiadiazolyl derivatives of dna polymerase theta inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6100077A (en)	1998-10-01	2000-08-08	The Trustees Of Columbia University In The City Of New York	Isolation of a gene encoding diacylglycerol acyltransferase
FR2840301B1 (fr)	2002-05-29	2007-03-23	Sanofi Synthelabo	Derives de phenyl-cyclohexyl-propanolamine, leur preparation et leur applicaton en therapeutique
PL374860A1 (en)	2002-07-09	2005-11-14	Bristol-Myers Squibb Company	Substituted heterocyclic derivatives useful as antidiabetic and antiobesity agents and method
US20050143384A1 (en) *	2003-10-30	2005-06-30	Eric Sartori	Amide thiadiazole inhibitors of plasminogen activator inhibitor-1
US7507832B2 (en)	2003-12-22	2009-03-24	Eli Lilly And Company	Triazole PPAR modulators
GB0427328D0 (en) *	2004-12-14	2005-01-19	Astrazeneca Ab	Chemical compounds
CA2610188A1 (en)	2005-06-11	2006-12-21	Astrazeneca Ab	Oxadiazole derivatives as dgat inhibitors
GB0511851D0 (en) *	2005-06-11	2005-07-20	Astrazeneca Ab	Chemical compounds
AU2007236049A1 (en)	2006-04-07	2007-10-18	High Point Pharmaceuticals, Llc	11beta-hydroxysteroid dehydrogenase type 1 active compounds

2010
- 2010-01-27 JP JP2011546921A patent/JP2012516312A/ja not_active Withdrawn
- 2010-01-27 CN CN2010800142290A patent/CN102365273A/zh active Pending
- 2010-01-27 US US13/145,665 patent/US8546391B2/en not_active Expired - Fee Related
- 2010-01-27 MA MA34128A patent/MA33069B1/fr unknown
- 2010-01-27 KR KR1020117019841A patent/KR20110112845A/ko not_active Application Discontinuation
- 2010-01-27 CA CA2750742A patent/CA2750742A1/fr not_active Abandoned
- 2010-01-27 BR BRPI1007414-7A patent/BRPI1007414A2/pt not_active IP Right Cessation
- 2010-01-27 MX MX2011007991A patent/MX2011007991A/es not_active Application Discontinuation
- 2010-01-27 AR ARP100100186A patent/AR075177A1/es not_active Application Discontinuation
- 2010-01-27 EA EA201170983A patent/EA201170983A1/ru unknown
- 2010-01-27 TW TW099102288A patent/TW201031645A/zh unknown
- 2010-01-27 PE PE2011001392A patent/PE20120362A1/es not_active Application Discontinuation
- 2010-01-27 EP EP10707597.0A patent/EP2391611B1/fr active Active
- 2010-01-27 AU AU2010209545A patent/AU2010209545A1/en not_active Abandoned
- 2010-01-27 NZ NZ594244A patent/NZ594244A/xx not_active IP Right Cessation
- 2010-01-27 WO PCT/FR2010/050124 patent/WO2010086551A1/fr active Application Filing
- 2010-01-28 UY UY0001032405A patent/UY32405A/es not_active Application Discontinuation
2011
- 2011-07-15 TN TN2011000353A patent/TN2011000353A1/fr unknown
- 2011-07-24 IL IL214260A patent/IL214260A0/en unknown
- 2011-07-25 EC EC2011011224A patent/ECSP11011224A/es unknown
- 2011-07-26 CR CR20110403A patent/CR20110403A/es unknown
- 2011-07-27 NI NI201100149A patent/NI201100149A/es unknown
- 2011-07-27 ZA ZA2011/05525A patent/ZA201105525B/en unknown
- 2011-07-28 DO DO2011000245A patent/DOP2011000245A/es unknown
- 2011-07-28 CL CL2011001839A patent/CL2011001839A1/es unknown
- 2011-07-28 CO CO11094698A patent/CO6400221A2/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
TW201031645A (en)	2010-09-01
CA2750742A1 (fr)	2010-08-05
CL2011001839A1 (es)	2012-01-06
MX2011007991A (es)	2011-11-18
NZ594244A (en)	2013-07-26
ECSP11011224A (es)	2011-08-31
DOP2011000245A (es)	2011-09-15
EP2391611B1 (fr)	2014-04-30
NI201100149A (es)	2011-11-01
EP2391611A1 (fr)	2011-12-07
TN2011000353A1 (fr)	2013-03-27
KR20110112845A (ko)	2011-10-13
UY32405A (es)	2010-08-31
EA201170983A1 (ru)	2012-03-30
WO2010086551A1 (fr)	2010-08-05
CO6400221A2 (es)	2012-03-15
US8546391B2 (en)	2013-10-01
AR075177A1 (es)	2011-03-16
ZA201105525B (en)	2012-12-27
CN102365273A (zh)	2012-02-29
JP2012516312A (ja)	2012-07-19
PE20120362A1 (es)	2012-05-04
AU2010209545A1 (en)	2011-08-18
MA33069B1 (fr)	2012-02-01
CR20110403A (es)	2011-09-21
US20120040984A1 (en)	2012-02-16
IL214260A0 (en)	2011-09-27

Publication	Publication Date	Title
BRPI1007414A2 (pt)	2018-03-06	derivados de tiadiazóis e de oxadiazóis, o respectivo preparo e a respectiva aplicação em terapêutica
WO2006134317A8 (en)	2008-02-21	Oxadiazole derivatives as dgat inhibitors
MY156938A (en)	2016-04-15	Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application
WO2011012816A3 (fr)	2011-12-22	Formulation pharmaceutique
WO2012044727A3 (en)	2012-06-07	Manufacturing process for pyrimidine derivatives
MY158982A (en)	2016-11-30	Heterocyclic compound
WO2009145456A3 (ko)	2010-01-21	헤테로사이클 유도체
WO2008145688A3 (en)	2009-03-26	Pyrrolopyridine compounds, process for their preparation, and their use as medicaments
NO20083427L (no)	2008-10-14	Cystoksiske midler omfattende nye tomaymycinderivater og deres terapeutiske anvendelse
WO2010128050A3 (en)	2011-05-05	Dihydroorotate - dehydrogenasee inhibitors as virostatic compounds
WO2010089510A3 (fr)	2010-09-30	Dérivés d'azaspiranyl-alkylcarbamates d'hétérocycles à 5 chaînons, leur préparation et leur application en thérapeutique
WO2009100936A3 (de)	2009-10-22	Neue aromatische fluorglykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
CA2798007C (en)	2018-10-23	Preparation of posaconazole intermediates
WO2008083950A8 (de)	2009-08-20	Spirocyclische tetronsäure-derivative
WO2009105969A8 (zh)	2010-10-07	埃坡霉素类似物、其药物组合物、用途及其制备方法
WO2011006935A3 (en)	2013-03-28	Tetrazole derivatives
NZ700356A (en)	2016-06-24	Pyrazole compounds as sglt1 inhibitors
WO2012140596A8 (en)	2013-05-30	Glycoside derivatives and uses thereof
WO2009003719A3 (en)	2009-08-13	Indane-amine derivatives, their preparation and use as medicaments
WO2008009750A3 (en)	2008-03-20	Macrocyclic compounds useful as bace inhibitors
EA201270302A1 (ru)	2012-07-30	Безводные формы производных пиридина
MX2011009898A (es)	2011-09-30	Proceso para la obtencion de derivados de acido propionico.
GB0602951D0 (en)	2006-03-29	Organic Compounds
MX2009000768A (es)	2009-01-28	Lactamas macrociclicas.
MX2010002007A (es)	2010-03-10	Sulfonas ciclicas sustituidas por amino-bencilo utiles como inhibidores de bace.

Legal Events

Date	Code	Title	Description
2018-03-13	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
2018-07-03	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]