BRPI0910259A2 - métodos de tratamento de inflamação - Google Patents
métodos de tratamento de inflamaçãoInfo
- Publication number
- BRPI0910259A2 BRPI0910259A2 BRPI0910259A BRPI0910259A BRPI0910259A2 BR PI0910259 A2 BRPI0910259 A2 BR PI0910259A2 BR PI0910259 A BRPI0910259 A BR PI0910259A BR PI0910259 A BRPI0910259 A BR PI0910259A BR PI0910259 A2 BRPI0910259 A2 BR PI0910259A2
- Authority
- BR
- Brazil
- Prior art keywords
- treatment methods
- inflammation treatment
- inflammation
- methods
- treatment
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A61P11/00—Drugs for disorders of the respiratory system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/08—Bronchodilators
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- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
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- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Vascular Medicine (AREA)
- Biochemistry (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3838108P | 2008-03-20 | 2008-03-20 | |
US3937108P | 2008-03-25 | 2008-03-25 | |
US4580708P | 2008-04-17 | 2008-04-17 | |
US12109508P | 2008-12-09 | 2008-12-09 | |
PCT/US2009/037887 WO2009117710A2 (en) | 2008-03-20 | 2009-03-20 | Methods of treating inflammation |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0910259A2 true BRPI0910259A2 (pt) | 2015-12-01 |
Family
ID=41091567
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0910259A BRPI0910259A2 (pt) | 2008-03-20 | 2009-03-20 | métodos de tratamento de inflamação |
Country Status (14)
Country | Link |
---|---|
US (2) | US20110262386A1 (pt) |
EP (2) | EP2254597A4 (pt) |
JP (2) | JP2011515416A (pt) |
KR (1) | KR20110014141A (pt) |
CN (2) | CN102088993A (pt) |
AU (2) | AU2009225389A1 (pt) |
BR (1) | BRPI0910259A2 (pt) |
CA (2) | CA2717071A1 (pt) |
CO (1) | CO6300848A2 (pt) |
EA (1) | EA201001529A1 (pt) |
IL (1) | IL207752A0 (pt) |
MX (1) | MX2010010198A (pt) |
NZ (1) | NZ588033A (pt) |
WO (2) | WO2009117706A2 (pt) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20110262386A1 (en) * | 2008-03-20 | 2011-10-27 | Carolus Therpeutics, Inc. | Methods of treating inflammation |
CA2716628A1 (en) * | 2008-03-24 | 2009-10-01 | Carolus Therapeutics, Inc. | Methods and compositions for treating atherosclerosis and related conditions |
WO2010056910A2 (en) * | 2008-11-12 | 2010-05-20 | Carolus Therapeutics, Inc. | Methods of treating cardiovascular disorders |
KR20120105429A (ko) * | 2009-09-23 | 2012-09-25 | 카롤러스 테라퓨틱스, 인코포레이티드 | 염증 치료 방법 |
EP2308485A1 (en) * | 2009-10-06 | 2011-04-13 | Dompé S.p.a. | Sulfonamides for the prevention of diabetes |
EP2308484A1 (en) | 2009-10-06 | 2011-04-13 | Dompé S.p.a. | Inhibitors of cxcr1/2 as adjuvants in the transplant of pancreatic islets |
WO2012125680A1 (en) | 2011-03-16 | 2012-09-20 | Novartis Ag | Methods of treating vasculitis using an il-17 binding molecule |
EP3354640A3 (en) * | 2011-04-13 | 2018-10-31 | Innovimmune Biotherapeutics, Inc. | Mif inhibitors and their uses |
TWI407964B (zh) * | 2011-05-10 | 2013-09-11 | Univ Fu Jen Catholic | 干擾性核糖核酸用於治療或減緩疼痛之用途 |
US11492383B2 (en) | 2011-06-24 | 2022-11-08 | Stephen D. Gillies | Light chain immunoglobulin fusion proteins and methods of use thereof |
CA2831154C (en) | 2011-06-30 | 2021-01-12 | Dignity Health | Use of pertussis toxin as a therapeutic agent |
US10596233B2 (en) | 2011-06-30 | 2020-03-24 | Dignity Health | Use of pertussis toxin as a therapeutic agent |
US9238689B2 (en) | 2011-07-15 | 2016-01-19 | Morpho Sys AG | Antibodies that are cross-reactive for macrophage migration inhibitory factor (MIF) and D-dopachrome tautomerase (D-DT) |
CN102357249A (zh) * | 2011-10-26 | 2012-02-22 | 广州赫尔氏药物开发有限公司 | 能够抑制耐药性结核杆菌的药物 |
CA3095012C (en) | 2012-05-01 | 2023-02-07 | Translatum Medicus Inc. | Methods for treating and diagnosing blinding eye diseases |
US10561676B2 (en) * | 2013-08-02 | 2020-02-18 | Syntrix Biosystems Inc. | Method for treating cancer using dual antagonists of CXCR1 and CXCR2 |
US10046002B2 (en) | 2013-08-02 | 2018-08-14 | Syntrix Biosystems Inc. | Method for treating cancer using chemokine antagonists |
WO2015051330A1 (en) | 2013-10-03 | 2015-04-09 | Oregon Health & Science University | RECOMBINANT POLYPEPTIDES COMPRISING MHC CLASS II α1 DOMAINS |
JP6863897B2 (ja) * | 2015-01-09 | 2021-04-21 | アダルタ・リミテッド | Cxcr4結合分子 |
TW201718851A (zh) * | 2015-09-18 | 2017-06-01 | 通用醫院公司 | 具有抗化學排斥(anti-fugetactic)性質之經修飾自然殺手細胞及其用途 |
WO2017106328A1 (en) * | 2015-12-14 | 2017-06-22 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
EP3389652B1 (en) | 2015-12-14 | 2022-09-28 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
MX2018010946A (es) | 2016-03-11 | 2019-05-23 | Ardea Biosciences Inc | Inhibidores de cxcr-2 para tratamiento de trastornos de artropatia por cristales. |
KR102645432B1 (ko) * | 2016-03-28 | 2024-03-11 | (주)아모레퍼시픽 | 피부 세포 분화 촉진용 조성물 및 피부 세포 분화 촉진 물질의 스크리닝 방법 |
CN109153722A (zh) | 2016-04-08 | 2019-01-04 | X4 制药有限公司 | 用于治疗癌症的方法 |
US20190134231A1 (en) * | 2016-04-21 | 2019-05-09 | The Board Of Regents Of The University Of Texas System | Methods and compositions for detecting aneurysms |
CN116903741A (zh) | 2016-06-20 | 2023-10-20 | 科马布有限公司 | 特异性结合于pd-l1的抗体或其抗原结合片段及其用途 |
WO2017223229A1 (en) | 2016-06-21 | 2017-12-28 | X4 Pharmaceuticals, Inc. | Cxcr4 inhibitors and uses thereof |
CN109562106B (zh) | 2016-06-21 | 2023-03-21 | X4 制药有限公司 | Cxcr4抑制剂及其用途 |
JP6994767B2 (ja) | 2016-06-21 | 2022-01-14 | エックス4 ファーマシューティカルズ, インコーポレイテッド | Cxcr4阻害剤およびその使用 |
AU2017339942B2 (en) | 2016-10-03 | 2023-06-29 | Dompe Farmaceutici S.P.A. | Prevention and treatment of diabetic nephropathy |
CN108355133A (zh) * | 2017-01-26 | 2018-08-03 | 中国医学科学院阜外医院 | 靶向cxcr7的药物组合物和方法 |
CN107964045B (zh) * | 2017-12-18 | 2021-04-23 | 南京医科大学 | 一种人鼠嵌合抗CXCR2全分子IgG及其应用 |
BR112020020930A2 (pt) | 2018-04-11 | 2021-03-02 | Ohio State Innovation Foundation | composição de liberação de fármaco, método para tratar um distúrbio oftalmológico e kit |
CA3102032A1 (en) | 2018-06-05 | 2019-12-12 | Anji Pharma (Us) Llc | Compositions and methods for treating pancreatitis |
JP2021526820A (ja) * | 2018-06-07 | 2021-10-11 | オンコワン・リサーチ・アンド・ディベロップメント・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 癌治療のための抗oxMIF/抗CD3抗体 |
US10548889B1 (en) | 2018-08-31 | 2020-02-04 | X4 Pharmaceuticals, Inc. | Compositions of CXCR4 inhibitors and methods of preparation and use |
MX2021007604A (es) * | 2018-12-26 | 2021-08-11 | Colgate Palmolive Co | Biomarcadores de desregulacion de neutrofilos como diagnostico de gingivitis. |
CN110133306B (zh) * | 2019-05-09 | 2023-04-07 | 北京勤邦生物技术有限公司 | 检测西马特罗的酶联免疫试剂盒及其应用 |
IL296338A (en) * | 2020-03-11 | 2022-11-01 | Biolinerx Ltd | cxcr4 inhibitor for the treatment of acute respiratory syndrome and viral infections |
US20210338626A1 (en) * | 2020-04-28 | 2021-11-04 | Dalcor Pharma Uk Ltd., Leatherhead, Zug Branch | Methods for treating or preventing a viral infection or inhibiting viral replication |
EP4320445A1 (en) | 2021-04-08 | 2024-02-14 | Joslin Diabetes Center, Inc. | Methods of diagnosing and predicting renal decline |
KR102561554B1 (ko) * | 2021-04-14 | 2023-07-28 | 부산대학교 산학협력단 | 치주질환 진단용 바이오마커 조성물, 치주질환 치료 효용성 평가용 바이오마커 조성물 및 이를 이용한 진단키트 |
WO2023150294A2 (en) * | 2022-02-04 | 2023-08-10 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Methods of detecting and treating cerebral aneurysms |
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US6030615A (en) * | 1993-05-17 | 2000-02-29 | The Picower Institute For Medical Research | Combination method for treating diseases caused by cytokine-mediated toxicity |
EP1741779A3 (en) * | 1993-05-17 | 2010-03-24 | The Picower Institute For Medical Research | Inhibition of migration inhibitory factor in the treatment of diseases involving cytokine mediated toxicity |
US20070072861A1 (en) * | 2000-03-27 | 2007-03-29 | Barbara Roniker | Method of using cyclooxygenase-2 inhibitors in the prevention of cardiovascular disorders |
JP2004531237A (ja) * | 2001-01-12 | 2004-10-14 | サイトカイン・ファーマサイエンシズ・インコーポレーテッド | マクロファージ遊走阻止因子による細胞障害性リンパ球応答の調節を調整するための方法及び組成物 |
WO2003047622A1 (fr) * | 2001-11-30 | 2003-06-12 | Jun Nishihira | Remedes pour la sclerose en plaques |
JP2003226653A (ja) * | 2001-11-30 | 2003-08-12 | Jun Nishihira | 多発性硬化症治療剤 |
US6656168B2 (en) * | 2001-12-18 | 2003-12-02 | Kimberly-Clark Worldwide, Inc. | Feminine care product with discrete areas of a skin wellness additive |
US20040009149A1 (en) * | 2002-02-27 | 2004-01-15 | Altman John D. | Multimeric binding complexes |
EP1483294B2 (en) * | 2002-03-01 | 2019-10-30 | Immunomedics, Inc. | Internalizing anti-cd74 antibodies and methods of use |
US20060233877A1 (en) * | 2002-11-25 | 2006-10-19 | Jallal Messadek | Betaine compositions |
TW200418829A (en) * | 2003-02-14 | 2004-10-01 | Avanir Pharmaceutics | Inhibitors of macrophage migration inhibitory factor and methods for identifying the same |
US20050202010A1 (en) * | 2003-08-29 | 2005-09-15 | Giroir Brett P. | Method of treatment and bioassay involving macrophage migration inhibitory factor (MIF) as cardiac-derived myocardial depressant factor |
WO2005065328A2 (en) * | 2003-12-30 | 2005-07-21 | The United States Of America, As Represented By The Department Of Veterans Affairs | Macrophage migration inhibitory factor (mif) as marker for urological inflammatory disease |
WO2006105666A1 (en) * | 2005-04-06 | 2006-10-12 | Queen's University At Kingston | Administration of macrophage targeted formulations of compounds which modulate cholesterol-metabolizing enzymes for treatment of atherosclerosis |
US7612181B2 (en) * | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
WO2007138961A1 (ja) * | 2006-05-29 | 2007-12-06 | Redox Bioscience Inc. | マクロファージ遊走阻止因子によって引き起こされる障害の予防乃至治療剤 |
US20110262386A1 (en) * | 2008-03-20 | 2011-10-27 | Carolus Therpeutics, Inc. | Methods of treating inflammation |
CA2716628A1 (en) * | 2008-03-24 | 2009-10-01 | Carolus Therapeutics, Inc. | Methods and compositions for treating atherosclerosis and related conditions |
WO2010056910A2 (en) * | 2008-11-12 | 2010-05-20 | Carolus Therapeutics, Inc. | Methods of treating cardiovascular disorders |
WO2010065491A2 (en) * | 2008-12-01 | 2010-06-10 | Carolus Therapeutics, Inc. | Methods of treating inflammatory disorders |
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2009
- 2009-03-20 US US12/918,964 patent/US20110262386A1/en not_active Abandoned
- 2009-03-20 EA EA201001529A patent/EA201001529A1/ru unknown
- 2009-03-20 CN CN2009801093284A patent/CN102088993A/zh active Pending
- 2009-03-20 KR KR1020107023480A patent/KR20110014141A/ko not_active Application Discontinuation
- 2009-03-20 EP EP09722541A patent/EP2254597A4/en not_active Withdrawn
- 2009-03-20 AU AU2009225389A patent/AU2009225389A1/en not_active Abandoned
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- 2009-03-20 BR BRPI0910259A patent/BRPI0910259A2/pt not_active IP Right Cessation
- 2009-03-20 CA CA2717071A patent/CA2717071A1/en not_active Abandoned
- 2009-03-20 WO PCT/US2009/037883 patent/WO2009117706A2/en active Application Filing
- 2009-03-20 CA CA2717365A patent/CA2717365A1/en not_active Abandoned
- 2009-03-20 WO PCT/US2009/037887 patent/WO2009117710A2/en active Application Filing
- 2009-03-20 NZ NZ588033A patent/NZ588033A/xx not_active IP Right Cessation
- 2009-03-20 JP JP2011501000A patent/JP2011515416A/ja active Pending
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- 2009-03-20 JP JP2011501003A patent/JP2011526244A/ja active Pending
- 2009-03-20 AU AU2009225385A patent/AU2009225385A1/en not_active Abandoned
- 2009-03-20 MX MX2010010198A patent/MX2010010198A/es active IP Right Grant
- 2009-03-20 EP EP09721240A patent/EP2252318A4/en not_active Withdrawn
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2010
- 2010-08-23 IL IL207752A patent/IL207752A0/en unknown
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CN102088993A (zh) | 2011-06-08 |
IL207752A0 (en) | 2010-12-30 |
US20110262386A1 (en) | 2011-10-27 |
CA2717071A1 (en) | 2009-09-24 |
CO6300848A2 (es) | 2011-07-21 |
AU2009225389A1 (en) | 2009-09-24 |
WO2009117710A3 (en) | 2010-01-21 |
JP2011526244A (ja) | 2011-10-06 |
CA2717365A1 (en) | 2009-09-24 |
EP2254597A2 (en) | 2010-12-01 |
EP2254597A4 (en) | 2012-04-18 |
NZ588033A (en) | 2012-11-30 |
EA201001529A1 (ru) | 2011-06-30 |
KR20110014141A (ko) | 2011-02-10 |
AU2009225385A1 (en) | 2009-09-24 |
EP2252318A2 (en) | 2010-11-24 |
WO2009117706A2 (en) | 2009-09-24 |
MX2010010198A (es) | 2010-12-21 |
JP2011515416A (ja) | 2011-05-19 |
US20110044988A1 (en) | 2011-02-24 |
CN102046199A (zh) | 2011-05-04 |
EP2252318A4 (en) | 2012-04-18 |
WO2009117710A2 (en) | 2009-09-24 |
WO2009117706A3 (en) | 2010-01-21 |
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