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BRPI0822221A2 - Composições aquosas e estáveis de ciclosporina - Google Patents

Composições aquosas e estáveis de ciclosporina

Info

Publication number
BRPI0822221A2
BRPI0822221A2 BRPI0822221-5A BRPI0822221A BRPI0822221A2 BR PI0822221 A2 BRPI0822221 A2 BR PI0822221A2 BR PI0822221 A BRPI0822221 A BR PI0822221A BR PI0822221 A2 BRPI0822221 A2 BR PI0822221A2
Authority
BR
Brazil
Prior art keywords
aqueous
stable
cyclosporine compositions
cyclosporine
compositions
Prior art date
Application number
BRPI0822221-5A
Other languages
English (en)
Inventor
William Francis Stringer
Original Assignee
Alcon Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Pharmaceuticals Ltd filed Critical Alcon Pharmaceuticals Ltd
Publication of BRPI0822221A2 publication Critical patent/BRPI0822221A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0822221-5A 2008-01-04 2008-11-17 Composições aquosas e estáveis de ciclosporina BRPI0822221A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1908808P 2008-01-04 2008-01-04
PCT/US2008/083789 WO2009088570A1 (en) 2008-01-04 2008-11-17 Stable aqueous cyclosporin compositions

Publications (1)

Publication Number Publication Date
BRPI0822221A2 true BRPI0822221A2 (pt) 2015-06-23

Family

ID=40853358

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0822221-5A BRPI0822221A2 (pt) 2008-01-04 2008-11-17 Composições aquosas e estáveis de ciclosporina

Country Status (11)

Country Link
US (1) US20090286718A1 (pt)
EP (1) EP2234629A4 (pt)
JP (1) JP2011508776A (pt)
KR (1) KR20100107462A (pt)
CN (1) CN101990437A (pt)
AU (1) AU2008346954A1 (pt)
BR (1) BRPI0822221A2 (pt)
CA (1) CA2710843A1 (pt)
MX (1) MX2010007295A (pt)
RU (1) RU2010132642A (pt)
WO (1) WO2009088570A1 (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010047681A1 (en) * 2008-10-24 2010-04-29 Bridge Pharma, Inc. Treating xerophthalmia with norketotifen
WO2010059894A1 (en) 2008-11-21 2010-05-27 Bridge Pharma, Inc. Ocular formulations of norketotifen
UA113627C2 (xx) * 2011-05-27 2017-02-27 Кристалічна форма циклоспорину a, фармацевтична композиція та спосіб лікування
US20130029919A1 (en) 2011-07-26 2013-01-31 Allergan, Inc. Two part formulation system for opthalmic delivery
DE102011108948A1 (de) * 2011-07-29 2013-01-31 Achim Göpferich Wässrige, kolloidale Lösungen von lipophilen Substanzen,insbesondere Arzneistofflösungen
KR101510764B1 (ko) * 2011-10-10 2015-04-10 김용남 사이클로스포린 함유 안약 조성물 및 그 제조방법
AU2012339701B8 (en) 2011-11-15 2017-11-16 Allergan, Inc. Autoclavable suspensions of cyclosporin A Form 2
JP6363506B2 (ja) 2011-11-15 2018-07-25 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ シクロスポリンａ２型の懸濁剤
FR2988297B1 (fr) 2012-03-22 2014-03-28 Thea Lab Solution ophtalmique aqueuse a base de ciclosporine a sans conservateur
AU2013305539B2 (en) 2012-08-24 2018-08-02 Sun Pharmaceutical Industries Limited Ophthalmic formulation of polyoxyl lipid or polyoxyl fatty acid and treatment of ocular conditions
JP2017007995A (ja) * 2015-06-25 2017-01-12 ライオン株式会社 洗眼剤組成物及び洗眼方法
KR101587385B1 (ko) * 2015-07-29 2016-01-21 국제약품공업주식회사 사이클로스포린 함유 무자극성의 안약조성물 및 편리한 제조방법
JP2018532809A (ja) 2015-11-10 2018-11-08 サン ファーマ グローバル エフジーイー 局所製剤およびその使用
PL3423076T3 (pl) * 2016-02-29 2024-08-19 Sun Pharmaceutical Industries Limited Preparaty do stosowania miejscowego zawierające cyklosporynę i ich zastosowania
RU2620568C1 (ru) * 2016-04-12 2017-05-26 Государственное бюджетное образовательное учреждение высшего профессионального образования "Санкт-Петербургский государственный педиатрический медицинский университет" Министерства здравоохранения Российской Федерации (ГБОУ ВПО СПбГПМУ Минздрава России) Препарат для лечения синдрома "сухого глаза"
AU2017325010A1 (en) * 2016-09-08 2019-03-28 Emergo Therapeutics, Inc. Mast cell stabilizers for treatment of hypercytokinemia and viral infection
JP2019533018A (ja) 2016-10-18 2019-11-14 エマーゴ セラピューティクス，インク． 慢性炎症状態の処置の為の肥満細胞安定剤
WO2019025986A1 (en) * 2017-08-02 2019-02-07 Shilpa Medicare Limited OPHTHALMIC COMPOSITIONS OF CYCLOSPORINE
KR102152506B1 (ko) * 2018-11-08 2020-09-07 한국식품연구원 산소제거 기능성 마스터배치 및 이의 제조방법
CA3132923A1 (en) * 2019-03-08 2020-09-17 Emphascience, Inc. Stable pharmaceutical formulations of peptide and protein drugs
CA3173164A1 (en) * 2020-03-23 2021-09-30 Brenda K. Mann Compositions and methods for treatment of ocular conditions
WO2023140854A1 (en) * 2022-01-21 2023-07-27 Elemental Cognition Inc. Interactive research assistant

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3631490B2 (ja) * 1992-05-13 2005-03-23 ノバルティス ファーマ株式会社 シクロスポリン含有眼科用組成物
MX9701946A (es) * 1997-03-14 1998-04-30 Arturo Jimenez Bayardo Solucion oftalmica transportadora.
JP3554514B2 (ja) * 1999-12-03 2004-08-18 松下電器産業株式会社 半導体装置及びその製造方法
US6984628B2 (en) * 2003-07-15 2006-01-10 Allergan, Inc. Ophthalmic compositions comprising trefoil factor family peptides
US20050059583A1 (en) * 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
US20060148686A1 (en) * 2004-12-30 2006-07-06 Bausch & Lomb Incorporated Ophthalmic compositions comprising steroid and cyclosporine for dry eye therapy
US7501393B2 (en) * 2005-07-27 2009-03-10 Allergan, Inc. Pharmaceutical compositions comprising cyclosporins
US20070087962A1 (en) * 2005-10-17 2007-04-19 Allergan, Inc. Pharmaceutical compositions comprising cyclosporins

Also Published As

Publication number Publication date
US20090286718A1 (en) 2009-11-19
EP2234629A1 (en) 2010-10-06
AU2008346954A1 (en) 2009-07-16
CN101990437A (zh) 2011-03-23
MX2010007295A (es) 2010-10-11
RU2010132642A (ru) 2012-02-10
KR20100107462A (ko) 2010-10-05
JP2011508776A (ja) 2011-03-17
WO2009088570A1 (en) 2009-07-16
EP2234629A4 (en) 2011-05-25
CA2710843A1 (en) 2009-07-16

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2329 DE 25-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.