[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

BRPI0821359A2 - Microcápsulas de lipídeos sólidas contendo hormônio de crescimento no núcleo sólido interno - Google Patents

Microcápsulas de lipídeos sólidas contendo hormônio de crescimento no núcleo sólido interno

Info

Publication number
BRPI0821359A2
BRPI0821359A2 BRPI0821359-3A BRPI0821359A BRPI0821359A2 BR PI0821359 A2 BRPI0821359 A2 BR PI0821359A2 BR PI0821359 A BRPI0821359 A BR PI0821359A BR PI0821359 A2 BRPI0821359 A2 BR PI0821359A2
Authority
BR
Brazil
Prior art keywords
growth hormone
solid
microcapsules containing
containing growth
internal
Prior art date
Application number
BRPI0821359-3A
Other languages
English (en)
Inventor
Joel Richard
Helen Gabriela Baldascini
Rita Agostinetto
Luisa De Angelis
Frantz Deschamps
Original Assignee
Merck Patent Ges Mit Beschränkter Haftung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Ges Mit Beschränkter Haftung filed Critical Merck Patent Ges Mit Beschränkter Haftung
Publication of BRPI0821359A2 publication Critical patent/BRPI0821359A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0821359-3A 2007-12-21 2008-11-21 Microcápsulas de lipídeos sólidas contendo hormônio de crescimento no núcleo sólido interno BRPI0821359A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07024906 2007-12-21
PCT/EP2008/009849 WO2009080164A1 (en) 2007-12-21 2008-11-21 Solid lipid microcapsules containing growth hormone in the inner solid core

Publications (1)

Publication Number Publication Date
BRPI0821359A2 true BRPI0821359A2 (pt) 2015-06-16

Family

ID=40566364

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0821359-3A BRPI0821359A2 (pt) 2007-12-21 2008-11-21 Microcápsulas de lipídeos sólidas contendo hormônio de crescimento no núcleo sólido interno

Country Status (15)

Country Link
US (1) US8729015B2 (pt)
EP (1) EP2231120B1 (pt)
JP (1) JP5773651B2 (pt)
KR (1) KR20100103846A (pt)
CN (1) CN101903014B (pt)
AR (1) AR069844A1 (pt)
AT (1) ATE514417T1 (pt)
AU (1) AU2008340785B8 (pt)
BR (1) BRPI0821359A2 (pt)
CA (1) CA2710062C (pt)
EA (1) EA201001002A1 (pt)
ES (1) ES2367093T3 (pt)
IL (1) IL206393A (pt)
WO (1) WO2009080164A1 (pt)
ZA (1) ZA201005167B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201001002A1 (ru) 2007-12-21 2011-06-30 Мерк Патент Гмбх Твердые липидные микрокапсулы, содержащие гормон роста во внутреннем твердом ядре
WO2010017965A2 (en) * 2008-08-11 2010-02-18 Merck Serono S.A. SOLID LIPID MICROCAPSULES CONTAINING hGH
CN102370630B (zh) * 2010-08-11 2014-04-02 中国科学院过程工程研究所 重组人生长激素rhGH长效缓释微囊及其制备方法
WO2013075068A1 (en) 2011-11-18 2013-05-23 Regeneron Pharmaceuticals, Inc. Polymer protein microparticles
AU2015280417B2 (en) 2014-06-24 2020-01-30 The Trustees Of Princeton University Process for encapsulating soluble biologics, therapeutics, and imaging agents
KR101602138B1 (ko) 2014-11-21 2016-03-10 강원대학교산학협력단 염화칼슘 미세입자가 봉입된 온도 의존성 고체지질입자 및 그 제조방법
AU2016378743A1 (en) 2015-12-22 2018-08-02 The Trustees Of Princeton University Process for encapsulating soluble biologics, therapeutics, and imaging agents
KR20170079409A (ko) * 2015-12-30 2017-07-10 한미약품 주식회사 지속형 인간 성장 호르몬 결합체의 신규 액상 제제
CN109380730B (zh) * 2017-08-09 2023-02-03 内蒙古伊利实业集团股份有限公司 微胶囊油脂及其制备方法
WO2019055539A1 (en) 2017-09-12 2019-03-21 Prudhomme Robert K CELLULOSIC POLYMER NANOPARTICLES AND METHODS OF FORMING THE SAME
US12186436B2 (en) 2018-07-19 2025-01-07 The Trustees Of Princeton University Triblock copolymer stabilizers for the formation of nanoparticles encapsulating soluble biologics, therapeutics, and imaging agents
US11731099B2 (en) 2018-07-20 2023-08-22 The Trustees Of Princeton University Method for controlling encapsulation efficiency and burst release of water soluble molecules from nanoparticles and microparticles produced by inverse flash nanoprecipitation
US20200147032A1 (en) 2018-11-14 2020-05-14 Robert K. Prud'homme Dihydromyricetin hot melt extrusion formulations and methods for forming them
CN114240934B (zh) * 2022-02-21 2022-05-10 深圳大学 一种基于肢端肥大症的图像数据分析方法及系统

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6068044A (ja) * 1983-09-24 1985-04-18 Tetsuo Kato 二重膜構造のマイクロカプセル
ATE90203T1 (de) * 1989-03-17 1993-06-15 Pitman Moore Inc Kontrollierte, verzoegerte wirkstofffreisetzung von makromolekularen proteinen.
US5219572A (en) * 1989-03-17 1993-06-15 Pitman-Moore, Inc. Controlled release delivery device for macromolecular proteins
EP1289645B1 (en) * 2000-04-27 2007-06-13 Verion Inc. Zero order release and temperature-controlled microcapsules and process for the preparation thereof
US6967028B2 (en) * 2000-07-31 2005-11-22 Mainelab Prolonged release microspheres for injectable administration
FR2820319B3 (fr) * 2001-02-08 2003-12-05 Ellipse Pharmaceuticals Procede de fabrication d'un comprime flottant incluant de l'alfuzosine et comprime obtenu
CA2516339A1 (en) * 2003-02-19 2004-09-02 Takeda Pharmaceutical Company Limited Dispersing agent for sustained-release preparation
JP5979697B2 (ja) * 2006-06-05 2016-08-24 ディーエスエム ニュートリショナル プロダクツ アーゲーＤＳＭ Ｎｕｔｒｉｔｉｏｎａｌ Ｐｒｏｄｕｃｔｓ ＡＧ 改善された殻を有するマイクロカプセル
EA201001002A1 (ru) 2007-12-21 2011-06-30 Мерк Патент Гмбх Твердые липидные микрокапсулы, содержащие гормон роста во внутреннем твердом ядре

Also Published As

Publication number Publication date
ZA201005167B (en) 2011-03-30
AU2008340785B8 (en) 2014-09-18
KR20100103846A (ko) 2010-09-28
JP5773651B2 (ja) 2015-09-02
AR069844A1 (es) 2010-02-24
IL206393A0 (en) 2010-12-30
US8729015B2 (en) 2014-05-20
EA201001002A1 (ru) 2011-06-30
CN101903014B (zh) 2014-04-16
ATE514417T1 (de) 2011-07-15
IL206393A (en) 2015-06-30
AU2008340785A1 (en) 2009-07-02
AU2008340785B2 (en) 2014-05-08
EP2231120A1 (en) 2010-09-29
CA2710062A1 (en) 2009-07-02
JP2011506499A (ja) 2011-03-03
CA2710062C (en) 2016-05-31
US20100310649A1 (en) 2010-12-09
ES2367093T3 (es) 2011-10-28
EP2231120B1 (en) 2011-06-29
CN101903014A (zh) 2010-12-01
WO2009080164A1 (en) 2009-07-02

Similar Documents

Publication Publication Date Title
BRPI0821359A2 (pt) Microcápsulas de lipídeos sólidas contendo hormônio de crescimento no núcleo sólido interno
DE602006011328D1 (de) Kapsel mit reduziertem Nachtropfen
EP2025266A4 (en) CUSHION DEVICE
IL212802A (en) Lipids and compositions for the delivery of therapeutics
DK2068886T3 (da) Lipidholdige præparater
BRPI0814137A2 (pt) Núcleo absorvente
BRPI0819623A2 (pt) núcelo absorvente
DE602007007826D1 (de) Supraleitende Magnetvorrichtung
BRPI0812753A2 (pt) Combinações de substância ativas acaricidas
IL213054A0 (en) Irritation element with additional effect
EP2400835A4 (en) INSECT PROTECTION AND LOCKS
ATE513470T1 (de) Kristalline fipronil-modifikation
DE602007005030D1 (de) Supraleitender Elektromagnet
ZA200901839B (en) Fishing casting device
ATE520307T1 (de) Stabilisierte malathion-mikrokapselformulierungen
FI20060481A0 (fi) Ravintorasvan annostelija
ITPT20060025A1 (it) Astuccio con alloggio interno
FI7509U1 (fi) Vetoketjuilla varustettu sängynpeite
FI7288U1 (fi) Kalapulla
PL379149A1 (pl) Aktywna rybka
AU307978S (en) Cassette for honey comb
ES1063205Y (es) Sabana encimera
IS8469A (is) Fiskiker
ITRM20080034U1 (it) Doppio asciugamano con cuscino interno
FR2911875B1 (fr) Thiacalix[2]thianthrenes

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.