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BRPI0814118A2 - Métodos cromatográficos - Google Patents

Métodos cromatográficos

Info

Publication number
BRPI0814118A2
BRPI0814118A2 BRPI0814118-5A2A BRPI0814118A BRPI0814118A2 BR PI0814118 A2 BRPI0814118 A2 BR PI0814118A2 BR PI0814118 A BRPI0814118 A BR PI0814118A BR PI0814118 A2 BRPI0814118 A2 BR PI0814118A2
Authority
BR
Brazil
Prior art keywords
chromatographical methods
chromatographical
methods
Prior art date
Application number
BRPI0814118-5A2A
Other languages
English (en)
Inventor
Josef Burg
Klaus Reichert
Axel Schroth
Hartmut Schurig
Axel Wessner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39119089&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0814118(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BRPI0814118A2 publication Critical patent/BRPI0814118A2/pt
Publication of BRPI0814118B1 publication Critical patent/BRPI0814118B1/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
    • B01D15/203—Equilibration or regeneration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B01D15/362—Cation-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J49/00—Regeneration or reactivation of ion-exchangers; Apparatus therefor
    • B01J49/50—Regeneration or reactivation of ion-exchangers; Apparatus therefor characterised by the regeneration reagents
    • B01J49/53—Regeneration or reactivation of ion-exchangers; Apparatus therefor characterised by the regeneration reagents for cationic exchangers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J49/00—Regeneration or reactivation of ion-exchangers; Apparatus therefor
    • B01J49/60—Cleaning or rinsing ion-exchange beds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
BRPI0814118-5A 2007-07-17 2008-07-15 Método para a regeneração da coluna de cromatografia de troca de cátion depois da eluição de compostos de interesse e método para obter uma eritropoietina BRPI0814118B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07013960.5 2007-07-17
EP07013960 2007-07-17
PCT/EP2008/005768 WO2009010271A2 (en) 2007-07-17 2008-07-15 Chromatographic methods

Publications (2)

Publication Number Publication Date
BRPI0814118A2 true BRPI0814118A2 (pt) 2015-02-03
BRPI0814118B1 BRPI0814118B1 (pt) 2019-04-09

Family

ID=39119089

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0814118-5A BRPI0814118B1 (pt) 2007-07-17 2008-07-15 Método para a regeneração da coluna de cromatografia de troca de cátion depois da eluição de compostos de interesse e método para obter uma eritropoietina

Country Status (20)

Country Link
US (2) US7846336B2 (pt)
EP (1) EP2173450B1 (pt)
JP (1) JP5025796B2 (pt)
KR (1) KR101164734B1 (pt)
CN (1) CN101754789B (pt)
AR (2) AR067536A1 (pt)
AU (1) AU2008277888B2 (pt)
BR (1) BRPI0814118B1 (pt)
CA (1) CA2692726C (pt)
CL (1) CL2008002054A1 (pt)
ES (1) ES2704013T3 (pt)
HR (1) HRP20182171T1 (pt)
IL (1) IL202942A (pt)
PE (1) PE20090448A1 (pt)
PL (1) PL2173450T3 (pt)
RU (1) RU2464066C2 (pt)
SI (1) SI2173450T1 (pt)
TR (1) TR201818614T4 (pt)
TW (1) TWI395619B (pt)
WO (1) WO2009010271A2 (pt)

Families Citing this family (14)

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CL2008002054A1 (es) 2007-07-17 2009-05-29 Hoffmann La Roche Metodo para la regeneracion de una columna de cromatografia de intercambio cationico despues de la elusion de eritropoyetina monopeguilada y metodo para obtener una eritropoyetina monopeguilada, incorporando el metodo de regeneracion de la columna de intercambio cationico.
CL2008002053A1 (es) * 2007-07-17 2009-05-22 Hoffmann La Roche Metodo para la purificacion de una eritropoyetina monopeguilada (epompeg) que consiste en proporcionar una solucion que contiene eritropoyetina mono, poli y no peguilada y hacerla pasar por dos pasos de cromatografia de intercambio cationico y metodo para producir epo mpeg que incluye metodo de purificacion.
JP5845170B2 (ja) * 2009-04-01 2016-01-20 ラティオファーム ゲーエムベーハー 組換えｆｓｈを精製する方法
WO2011038894A1 (en) * 2009-10-01 2011-04-07 F. Hoffmann-La Roche Ag Protein a chromatography
EP3133083B1 (en) 2009-10-01 2020-02-19 F. Hoffmann-La Roche AG Multistep final filtration
PL2616101T3 (pl) * 2010-09-14 2015-01-30 Hoffmann La Roche Sposób oczyszczania pegylowanej erytropoetyny
SG190891A1 (en) 2010-12-21 2013-07-31 Hoffmann La Roche Chromatography equipment characterization
CN103115998B (zh) * 2013-02-04 2014-10-15 田晓露 一种离子色谱保护柱柱芯处理再利用方法
CN104368402A (zh) * 2013-08-13 2015-02-25 内蒙古蒙牛乳业（集团）股份有限公司 一种氨基酸分析用的阳离子交换树脂的再生方法
CA2923133C (en) * 2013-09-04 2019-05-28 Emd Millipore Corporation Methods of cleaning a protein a based affinity chromatography column
US20180057731A1 (en) * 2016-08-31 2018-03-01 Battelle Memorial Institute Polymer Matrix Particles For Inhibitingscale Formation In Oil And Gas Wells
JP7097433B2 (ja) 2017-08-17 2022-07-07 ジャスト－エヴォテック バイオロジックス、インコーポレイテッド 宿主細胞ガレクチンおよび他の夾雑物からグリコシル化タンパク質を精製する方法
CN112933660A (zh) * 2020-09-11 2021-06-11 石家庄新奥环保科技有限公司 一种离子色谱保护柱再生方法
CN115032317B (zh) * 2022-06-29 2024-03-26 科兴生物制药股份有限公司 重组人促红细胞生成素的检测方法

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Also Published As

Publication number Publication date
CN101754789B (zh) 2013-10-23
IL202942A (en) 2016-10-31
WO2009010271A2 (en) 2009-01-22
AR067536A1 (es) 2009-10-14
CN101754789A (zh) 2010-06-23
BRPI0814118B1 (pt) 2019-04-09
CA2692726A1 (en) 2009-01-22
CL2008002054A1 (es) 2009-05-29
EP2173450B1 (en) 2018-10-31
AU2008277888A1 (en) 2009-01-22
SI2173450T1 (sl) 2019-02-28
CA2692726C (en) 2015-02-24
EP2173450A2 (en) 2010-04-14
TW200911373A (en) 2009-03-16
KR20100037145A (ko) 2010-04-08
RU2464066C2 (ru) 2012-10-20
JP2010533845A (ja) 2010-10-28
US8795533B2 (en) 2014-08-05
KR101164734B1 (ko) 2012-07-12
AU2008277888B2 (en) 2012-08-16
ES2704013T3 (es) 2019-03-13
US7846336B2 (en) 2010-12-07
US20090101585A1 (en) 2009-04-23
TWI395619B (zh) 2013-05-11
WO2009010271A3 (en) 2009-04-02
RU2010105312A (ru) 2011-08-27
TR201818614T4 (tr) 2019-01-21
AR110693A2 (es) 2019-04-24
JP5025796B2 (ja) 2012-09-12
HRP20182171T1 (hr) 2019-02-22
US20110065903A1 (en) 2011-03-17
PL2173450T3 (pl) 2019-03-29
PE20090448A1 (es) 2009-04-18

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06A Notification to applicant to reply to the report for non-patentability or inadequacy of the application [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

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