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BRPI0718145A2 - Método de micronização - Google Patents

Método de micronização

Info

Publication number
BRPI0718145A2
BRPI0718145A2 BRPI0718145-0A2A BRPI0718145A BRPI0718145A2 BR PI0718145 A2 BRPI0718145 A2 BR PI0718145A2 BR PI0718145 A BRPI0718145 A BR PI0718145A BR PI0718145 A2 BRPI0718145 A2 BR PI0718145A2
Authority
BR
Brazil
Prior art keywords
micronization method
micronization
Prior art date
Application number
BRPI0718145-0A2A
Other languages
English (en)
Inventor
Israel Nur
Liliana Bar
Original Assignee
Omrix Biopharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omrix Biopharmaceuticals Ltd filed Critical Omrix Biopharmaceuticals Ltd
Publication of BRPI0718145A2 publication Critical patent/BRPI0718145A2/pt
Publication of BRPI0718145B1 publication Critical patent/BRPI0718145B1/pt
Publication of BRPI0718145B8 publication Critical patent/BRPI0718145B8/pt

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C19/00Other disintegrating devices or methods
    • B02C19/06Jet mills
    • B02C19/061Jet mills of the cylindrical type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36Blood coagulation or fibrinolysis factors
    • A61K38/363Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4833Thrombin (3.4.21.5)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02CCRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
    • B02C19/00Other disintegrating devices or methods
    • B02C19/06Jet mills

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Food Science & Technology (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Disintegrating Or Milling (AREA)
  • Medicinal Preparation (AREA)
BRPI0718145A 2006-11-02 2007-10-30 método de micronização BRPI0718145B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85604206P 2006-11-02 2006-11-02
PCT/IL2007/001318 WO2008053475A1 (en) 2006-11-02 2007-10-30 Method of micronization

Publications (3)

Publication Number Publication Date
BRPI0718145A2 true BRPI0718145A2 (pt) 2013-11-05
BRPI0718145B1 BRPI0718145B1 (pt) 2020-12-08
BRPI0718145B8 BRPI0718145B8 (pt) 2021-05-25

Family

ID=38988026

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0718145A BRPI0718145B8 (pt) 2006-11-02 2007-10-30 método de micronização

Country Status (12)

Country Link
US (1) US8322637B2 (pt)
EP (1) EP2106296B1 (pt)
JP (1) JP5373618B2 (pt)
KR (1) KR101411933B1 (pt)
CN (1) CN101534952B (pt)
AU (1) AU2007315724B2 (pt)
BR (1) BRPI0718145B8 (pt)
CA (1) CA2667969C (pt)
ES (1) ES2649755T3 (pt)
RU (1) RU2443413C2 (pt)
TW (1) TWI411450B (pt)
WO (1) WO2008053475A1 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2322279B1 (en) 2009-11-17 2016-05-11 Biohyst Overseas Sagl Biomass crushing and separating device
CA2787883C (en) 2010-01-28 2019-02-19 Erez Ilan Method for improved fibrin sealing
US8846849B2 (en) 2011-05-13 2014-09-30 Ethicon, Inc. Tissue sealants from plasma derived proteins
US9056092B2 (en) * 2011-12-02 2015-06-16 Ethicon, Inc. Hemostatic bioabsorbable device with polyethylene glycol binder
IN2014DN05901A (pt) 2011-12-29 2015-06-05 Omrix Biopharmaceuticals Ltd
JP2014200721A (ja) * 2013-04-02 2014-10-27 茂明 丸尾 ジェットミル装置
KR20170028992A (ko) * 2014-07-18 2017-03-14 엠에스디 웰컴 트러스트 힐레맨 랩스 피브이티. 리미티드 열안정성 동결 건조된 로타바이러스 백신 제형 및 이의 제조 방법
CN107413489B (zh) * 2017-04-26 2019-11-12 阜阳市鑫源建材有限公司 一种利用超临界二氧化碳制备超细矿渣粉的方法
WO2023119277A1 (en) 2021-12-21 2023-06-29 Omrix Biopharmaceuticals Ltd. Highly soluble fibrinogen compositions
CN116942532B (zh) * 2023-09-20 2023-12-12 北京爱力佳医药科技有限公司 一种粉状药物制备装置
CN117244668B (zh) * 2023-11-17 2024-03-22 哈尔滨瀚邦医疗科技有限公司 一种生物止血材料粉碎筛选系统

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4502641A (en) 1981-04-29 1985-03-05 E. I. Du Pont De Nemours And Company Fluid energy mill with differential pressure means
CN1013648B (zh) * 1986-06-27 1991-08-28 匈牙利铝工业托拉斯 一种气流粉碎机
US5021554A (en) * 1989-02-24 1991-06-04 Eli Lilly And Company Process for protein particle size reduction using a fluid-energy mill
CN1031450C (zh) * 1989-05-15 1996-04-03 佳能株式会社 气流分级器,制备色料的方法和装置
EP0534178B1 (en) 1991-09-27 2001-04-18 Omrix Biopharmaceuticals S.A. Improved tissue glue prepared by using cryoprecipitate
ATE146359T1 (de) * 1992-01-21 1997-01-15 Stanford Res Inst Int Verbessertes verfahren zur herstellung von mikronisierter polypeptidarzneimitteln
RU2029621C1 (ru) 1992-10-12 1995-02-27 Владимир Николаевич Сорокин Способ вихревого измельчения материала
US5855326A (en) 1997-05-23 1999-01-05 Super Fine Ltd. Process and device for controlled cominution of materials in a whirl chamber
HU228899B1 (en) 2001-05-21 2013-06-28 Omrix Biopharm Sa Removal of plasmin(ogen)from protein solutions
US6789756B2 (en) * 2002-02-20 2004-09-14 Super Fine Ltd. Vortex mill for controlled milling of particulate solids
GB0219815D0 (en) * 2002-08-24 2002-10-02 Accentus Plc Preparation of small crystals
US20040121003A1 (en) * 2002-12-19 2004-06-24 Acusphere, Inc. Methods for making pharmaceutical formulations comprising deagglomerated microparticles
CN1295021C (zh) * 2004-04-15 2007-01-17 杨富茂 机械湍流磨

Also Published As

Publication number Publication date
BRPI0718145B1 (pt) 2020-12-08
CN101534952A (zh) 2009-09-16
RU2009119390A (ru) 2010-12-10
WO2008053475A1 (en) 2008-05-08
RU2443413C2 (ru) 2012-02-27
TW200826973A (en) 2008-07-01
EP2106296A1 (en) 2009-10-07
CA2667969C (en) 2014-10-14
EP2106296B1 (en) 2017-09-06
AU2007315724B2 (en) 2012-04-12
AU2007315724A1 (en) 2008-05-08
KR20090076945A (ko) 2009-07-13
CA2667969A1 (en) 2008-05-08
US20100068196A1 (en) 2010-03-18
BRPI0718145B8 (pt) 2021-05-25
CN101534952B (zh) 2012-10-31
TWI411450B (zh) 2013-10-11
JP2010509047A (ja) 2010-03-25
KR101411933B1 (ko) 2014-06-27
ES2649755T3 (es) 2018-01-15
US8322637B2 (en) 2012-12-04
JP5373618B2 (ja) 2013-12-18

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 08/12/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/10/2007 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 17A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2798 DE 20-08-2024 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.