BRPI0518209A - angiopoietin-2-specific binding agents - Google Patents
angiopoietin-2-specific binding agentsInfo
- Publication number
- BRPI0518209A BRPI0518209A BRPI0518209-3A BRPI0518209A BRPI0518209A BR PI0518209 A BRPI0518209 A BR PI0518209A BR PI0518209 A BRPI0518209 A BR PI0518209A BR PI0518209 A BRPI0518209 A BR PI0518209A
- Authority
- BR
- Brazil
- Prior art keywords
- specific binding
- binding agents
- angiopoietin
- antibodies
- disclosed
- Prior art date
Links
Landscapes
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
AGENTES DE LIGAçãO ESPECìFICOS à ANGlOPOIETINA-2. São divulgados agentes de ligação especifica, tais como anti-corpos totalmente humanos, que se ligam à angiopoietina-2. Também divulgados são fragmentos de cadeia pesada, fragmentos de cadeia leve e CDRs dos anticorpos, bem como métodos de fabricação e uso dos anticorpos.ANGlOPOIETIN-2 SPECIFIC BINDING AGENTS. Specific binding agents, such as fully human antibodies, that bind to angiopoietin-2 are disclosed. Also disclosed are heavy chain fragments, light chain fragments and CDRs of antibodies, as well as methods of making and using antibodies.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62016104P | 2004-10-19 | 2004-10-19 | |
US10/982,440 US7658924B2 (en) | 2001-10-11 | 2004-11-04 | Angiopoietin-2 specific binding agents |
PCT/US2005/037911 WO2006045049A1 (en) | 2004-10-19 | 2005-10-19 | Angiopoietin-2 specific binding agents |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0518209A true BRPI0518209A (en) | 2008-11-04 |
Family
ID=39608222
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0518209-3A BRPI0518209A (en) | 2004-10-19 | 2005-10-19 | angiopoietin-2-specific binding agents |
Country Status (10)
Country | Link |
---|---|
JP (2) | JP2008520188A (en) |
CN (1) | CN101495513B (en) |
BR (1) | BRPI0518209A (en) |
EA (1) | EA011866B1 (en) |
IL (1) | IL182279A0 (en) |
MA (1) | MA29015B1 (en) |
MX (1) | MX2007004247A (en) |
RU (2) | RU2404992C2 (en) |
SG (1) | SG156668A1 (en) |
ZA (1) | ZA200704020B (en) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0518209A (en) * | 2004-10-19 | 2008-11-04 | Amgen Inc | angiopoietin-2-specific binding agents |
JO3182B1 (en) * | 2009-07-29 | 2018-03-08 | Regeneron Pharma | High Affinity Human Antibodies to Human Angiopoietin-2 |
EA022546B1 (en) * | 2011-09-28 | 2016-01-29 | Федеральное Государственное Бюджетное Учреждение Науки Институт Биоорганической Химии Им. Академиков М.М. Шемякина И Ю.А. Овчинникова Российской Академии Наук | Method for inhibiting growth of ehrlich carcinoma in laboratory animal |
PE20142361A1 (en) * | 2011-09-30 | 2015-01-16 | Dana Farber Cancer Inst Inc | THERAPEUTIC PEPTIDES |
EA033387B1 (en) * | 2012-01-23 | 2019-10-31 | Regeneron Pharma | STABILIZED FORMULATIONS CONTAINING ANTI-Ang2 ANTIBODIES |
US9534007B2 (en) | 2012-12-21 | 2017-01-03 | The Regents Of The University Of California | Methods and compositions for treatment of cyanide and hydrogen sulfide toxicity |
AU2014266223B2 (en) | 2013-05-14 | 2020-06-25 | Eisai R&D Management Co., Ltd. | Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds |
AR100270A1 (en) * | 2014-05-19 | 2016-09-21 | Lilly Co Eli | ANTIBODIES ANG2 |
EP4089076A1 (en) | 2014-08-28 | 2022-11-16 | Eisai R&D Management Co., Ltd. | High-purity quinoline derivative and method for manufacturing same |
RS65049B1 (en) | 2015-02-25 | 2024-02-29 | Eisai R&D Man Co Ltd | Method for suppressing bitterness of quinoline derivative |
KR20240064733A (en) | 2015-03-04 | 2024-05-13 | 머크 샤프 앤드 돔 코포레이션 | Combination of a pd-1 antagonist and a vegfr/fgfr/ret tyrosine kinase inhibitor for treating cancer |
SG11201710198YA (en) | 2015-06-16 | 2018-01-30 | Eisai R&D Man Co Ltd | Anticancer agent |
CN106512006A (en) * | 2016-07-25 | 2017-03-22 | 广州道瑞医药科技有限公司 | Application of ANGPT2 secretion inhibitor to preparation of medicine for treating hemangiomas |
CN106075448A (en) * | 2016-07-25 | 2016-11-09 | 广州道瑞医药科技有限公司 | ANGPT2 inhibitor is used for treating the application in angiomatous medicine in preparation |
CN109096368B (en) * | 2018-09-30 | 2021-07-20 | 华南理工大学 | Polypeptide with antioxidant and liver protecting activities, gene for encoding polypeptide, preparation method and application thereof |
JP7177284B2 (en) * | 2019-02-25 | 2022-11-22 | ファームアブシン・インコーポレイテッド | Anti-ANG2 antibody and use thereof |
CN112126671B (en) * | 2020-08-18 | 2021-08-31 | 中山大学附属第五医院 | Application of streptococcus agalactiae streptococcus agalactiae in treating endometriosis |
CN116265487A (en) * | 2021-12-16 | 2023-06-20 | 三优生物医药(上海)有限公司 | anti-ANG 2-VEGF bispecific antibodies and uses thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1165115B1 (en) * | 1999-03-26 | 2003-05-28 | Regeneron Pharmaceuticals, Inc. | Modulation of vascular permeability by mean of tie2 receptor activators |
US7521053B2 (en) * | 2001-10-11 | 2009-04-21 | Amgen Inc. | Angiopoietin-2 specific binding agents |
US7205275B2 (en) * | 2001-10-11 | 2007-04-17 | Amgen Inc. | Methods of treatment using specific binding agents of human angiopoietin-2 |
CA2473970C (en) * | 2001-10-12 | 2013-05-28 | Monosolrx Llc | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
BRPI0518209A (en) * | 2004-10-19 | 2008-11-04 | Amgen Inc | angiopoietin-2-specific binding agents |
-
2005
- 2005-10-19 BR BRPI0518209-3A patent/BRPI0518209A/en not_active IP Right Cessation
- 2005-10-19 CN CN200580043569.5A patent/CN101495513B/en not_active Expired - Fee Related
- 2005-10-19 RU RU2007118670/13A patent/RU2404992C2/en not_active IP Right Cessation
- 2005-10-19 MX MX2007004247A patent/MX2007004247A/en active IP Right Grant
- 2005-10-19 JP JP2007538066A patent/JP2008520188A/en active Pending
- 2005-10-19 SG SG200907008-7A patent/SG156668A1/en unknown
- 2005-10-19 EA EA200700876A patent/EA011866B1/en not_active IP Right Cessation
-
2007
- 2007-03-28 IL IL182279A patent/IL182279A0/en unknown
- 2007-05-11 MA MA29892A patent/MA29015B1/en unknown
- 2007-05-18 ZA ZA200704020A patent/ZA200704020B/en unknown
-
2010
- 2010-08-05 RU RU2010132956/10A patent/RU2010132956A/en not_active Application Discontinuation
-
2011
- 2011-03-30 JP JP2011075243A patent/JP2011207882A/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
IL182279A0 (en) | 2007-07-24 |
CN101495513A (en) | 2009-07-29 |
RU2404992C2 (en) | 2010-11-27 |
RU2010132956A (en) | 2012-02-10 |
MA29015B1 (en) | 2007-11-01 |
CN101495513B (en) | 2014-08-06 |
MX2007004247A (en) | 2007-06-12 |
JP2008520188A (en) | 2008-06-19 |
SG156668A1 (en) | 2009-11-26 |
EA200700876A1 (en) | 2007-10-26 |
EA011866B1 (en) | 2009-06-30 |
ZA200704020B (en) | 2008-06-25 |
JP2011207882A (en) | 2011-10-20 |
RU2007118670A (en) | 2008-12-27 |
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Legal Events
Date | Code | Title | Description |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06H | Technical and formal requirements: requirement cancelled [chapter 6.8 patent gazette] |
Free format text: REF. A RPI NO 2153 DE 10/04/2012. ANULACAO DA EXIGENCIA 6.6 POR TER SIDO INDEVIDA. REQUERENTE NAO APRESENTOU RESPOSTA A EXIGENCIA CONFORME DISPOE A RESOLUCAO 207 DE 24/04/2009, ENTRETANTO, A RESPOSTA CONSTA NO FORMULARIO DE DEPOSITO. |
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 11A ANUIDADE. |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |