BRPI0517883B8 - complexos de fosfato de cálcio estabilizado - Google Patents
complexos de fosfato de cálcio estabilizado Download PDFInfo
- Publication number
- BRPI0517883B8 BRPI0517883B8 BRPI0517883A BRPI0517883A BRPI0517883B8 BR PI0517883 B8 BRPI0517883 B8 BR PI0517883B8 BR PI0517883 A BRPI0517883 A BR PI0517883A BR PI0517883 A BRPI0517883 A BR PI0517883A BR PI0517883 B8 BRPI0517883 B8 BR PI0517883B8
- Authority
- BR
- Brazil
- Prior art keywords
- calcium phosphate
- complexes
- stabilized calcium
- phosphate complexes
- stabilized
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/69—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing fluorine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Dental Preparations (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
complexos de fosfato de cálcio estabilizado. a presente invenção refere-se a um complexo de fosfato de cálcio amorfo e/ou fosfato de fluoreto de cálcio amorfo estabilizado por fosfopeptídeos, onde o complexo é formado em um ph abaixo de 7,0. os métodos para a preparação de tais complexos são também fornecidos. os complexos são úteis em aparelhos dentários, em particular em remineralização dentária.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2004906762A AU2004906762A0 (en) | 2004-11-25 | Stabilized calcium phosphate complexes | |
AU2004906762 | 2004-11-25 | ||
PCT/AU2005/001781 WO2006056013A1 (en) | 2004-11-25 | 2005-11-24 | Stabilized calcium phosphate complexes |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI0517883A BRPI0517883A (pt) | 2008-10-21 |
BRPI0517883B1 BRPI0517883B1 (pt) | 2015-06-23 |
BRPI0517883B8 true BRPI0517883B8 (pt) | 2020-03-24 |
Family
ID=36497671
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0517883A BRPI0517883B8 (pt) | 2004-11-25 | 2005-11-24 | complexos de fosfato de cálcio estabilizado |
Country Status (12)
Country | Link |
---|---|
US (3) | US8609071B2 (pt) |
EP (2) | EP1827366B1 (pt) |
JP (1) | JP5000525B2 (pt) |
CN (1) | CN101098675B (pt) |
AU (1) | AU2005309327B2 (pt) |
BR (1) | BRPI0517883B8 (pt) |
CA (1) | CA2589270C (pt) |
MX (1) | MX2007006254A (pt) |
NZ (1) | NZ555335A (pt) |
PL (1) | PL1827366T3 (pt) |
RU (1) | RU2404738C2 (pt) |
WO (1) | WO2006056013A1 (pt) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9668945B2 (en) | 2006-02-09 | 2017-06-06 | The University Of Melbourne | Fluoride composition and methods for dental mineralization |
BRPI0710292A2 (pt) | 2006-04-05 | 2011-08-09 | Cadbury Adams Usa Llc | complexo de fosfato de cálcio em uma goma de mascar contendo ácido |
US8133476B2 (en) | 2006-04-05 | 2012-03-13 | Cadbury Adams Usa Llc | Calcium phosphate complex and salts in oral delivery systems |
MX2008012520A (es) | 2006-04-05 | 2008-10-10 | Cadbury Adams Usa Llc | Impacto del complejo del fosfato de calcio en la caries dental. |
CA2695946C (en) | 2007-08-09 | 2017-06-13 | The Board Of Regents Of The University Of Texas System | Bi-layered bone-like scaffolds |
WO2010006192A1 (en) * | 2008-07-09 | 2010-01-14 | Board Of Regents Of The University Of Nebraska | Functional micelles for hard tissue targeted delivery of chemicals |
JP2010047494A (ja) * | 2008-08-20 | 2010-03-04 | Gc Corp | 歯牙塗布用組成物 |
AU2011250934B2 (en) * | 2010-05-11 | 2016-02-25 | Howmedica Osteonics Corp., | Organophosphorous, multivalent metal compounds, & polymer adhesive interpenetrating network compositions & methods |
WO2012145619A1 (en) * | 2011-04-20 | 2012-10-26 | University Of Rochester | Nanoparticle dental composition and method of making |
JP2013163656A (ja) * | 2012-02-10 | 2013-08-22 | Gc Corp | 歯磨剤 |
US10314771B2 (en) | 2013-02-28 | 2019-06-11 | University Of Tennessee Research Foundation | Methods and compositions for preventing and treating tooth erosion |
US9744108B2 (en) | 2013-02-28 | 2017-08-29 | University Of Tennessee Research Foundation | Methods and compositions for preventing and treating tooth erosion |
JP6621406B2 (ja) | 2013-07-23 | 2019-12-18 | ザ ユニバーシティー オブ メルボルンThe University of Melbourne | 歯の石灰化のための組成物および方法 |
WO2015023773A2 (en) | 2013-08-14 | 2015-02-19 | University Of Tennessee Research Foundation | Tooth remineralization compositions and methods |
ES2669548T3 (es) | 2013-09-25 | 2018-05-28 | Credentis Ag | Producto de cuidado dental para el blanqueamiento de los dientes |
EP2853256A1 (en) | 2013-09-25 | 2015-04-01 | Credentis AG | Dental care product for tooth whitening |
US9168114B2 (en) | 2013-10-17 | 2015-10-27 | B & D Dental Corp. | Method of making a dental prosthesis |
MY176788A (en) | 2013-12-24 | 2020-08-21 | Univ Melbourne | Stabilized stannous compositions |
RU2017104238A (ru) * | 2014-07-11 | 2018-08-13 | Конинклейке Филипс Н.В. | Система для состава по уходу за полостью рта, обеспечивающая аморфный фосфат кальция |
JP2017522894A (ja) | 2014-07-31 | 2017-08-17 | アモーフィカル リミテッド. | カプセル化された非晶質炭酸カルシウム組成物 |
JP2016102069A (ja) * | 2014-11-27 | 2016-06-02 | 株式会社ジーシー | 歯面清掃方法、歯面清掃用組成物、及びその使用方法 |
SG11201705170UA (en) * | 2014-12-24 | 2017-07-28 | Univ Melbourne | Mineralization fluoride compositions |
US10219986B2 (en) | 2015-03-04 | 2019-03-05 | Modern Ideas LLC | Stabilized calcium phosphate and methods of forming same |
BR112018008221A2 (pt) * | 2015-10-26 | 2018-10-30 | Basf Se | métodos de ligação ou alvejamento à superfície de esmalte e/ou dentina, reparo ou inibição da erosão dentária, promoção da remineralização dentária, e/ou intensificação dos efeitos anti-cavidade de fluoreto e de produção de um produto para cuidado oral compreendendo habp, dentifrício, uso de habp na fabricação de uma composição para cuidado oral, composição para cuidado oral que compreende habp, polipeptídeo de ligação de hidroxiapatita, e, composição de goma de mascar. |
US9956314B2 (en) | 2016-01-26 | 2018-05-01 | Modern Ideas LLC | Adhesive for use with bone and bone-like structures |
CN109152936B (zh) | 2016-05-26 | 2021-08-27 | 3M创新有限公司 | 治疗牙膏及相关方法及试剂盒 |
EP3538053A1 (en) | 2016-11-08 | 2019-09-18 | Dentherapy Ltd | Compositions comprising fluoride and calcium and method for preparing them |
CN110475533A (zh) | 2017-03-14 | 2019-11-19 | 墨尔本大学 | 治疗牙龈炎 |
CA3144016A1 (en) * | 2019-07-04 | 2021-01-07 | Ferton Holding S.A. | Composition for the remineralization of teeth |
CN110483622B (zh) * | 2019-08-26 | 2021-06-11 | 无限极(中国)有限公司 | 酪蛋白磷酸肽及其制备方法、应用 |
US11154470B1 (en) | 2020-07-31 | 2021-10-26 | vVardis AG | Anti-inflammatory and senolytic dental care product with tooth whitening characteristics |
EP3984517A1 (en) | 2020-10-19 | 2022-04-20 | Credentis AG | Accelerating tooth remineralisation and bone regeneration with self-assembling peptides and amorphous calcium phosphate |
CN112499607B (zh) * | 2020-10-29 | 2022-07-26 | 南京师范大学 | 用于多磷酸肽富集及磷酸化位点鉴定的纳米磷酸钙的制备方法及其产品和应用 |
GB202110114D0 (en) | 2021-07-14 | 2021-08-25 | Dentherapy Ltd | Oral care compositions for use in treaatment |
CN114343060B (zh) * | 2021-12-30 | 2023-07-25 | 河南金丹乳酸科技股份有限公司 | 一种乳酸生产中提高菌体渣中蛋白含量的工艺 |
WO2024089262A1 (en) | 2022-10-28 | 2024-05-02 | Queen Mary University Of London | Toothpaste composition |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4522805A (en) * | 1983-06-08 | 1985-06-11 | Norman Gordon | Tooth and gum dentifrice |
US5015628A (en) | 1986-06-12 | 1991-05-14 | The University Of Melbourne | Anticariogenic phosphopeptides |
CA1315480C (en) * | 1986-06-12 | 1993-03-30 | Eric Charles Reynolds | Phosphopeptides |
US6056930A (en) * | 1989-05-24 | 2000-05-02 | American Dental Association Health Foundation | Methods and compositions for mineralizing and fluoridating calcified tissues |
US5227154A (en) * | 1991-08-22 | 1993-07-13 | The University Of Melbourne | Phosphopeptides for the treatment of dental calculus |
ATE189606T1 (de) | 1992-06-29 | 2000-02-15 | Univ Melbourne | Behandlung von empfindlichen zähnen |
JP3340265B2 (ja) | 1994-11-21 | 2002-11-05 | 一枝 山岸 | 歯の漂白剤 |
JP4040705B2 (ja) | 1996-01-24 | 2008-01-30 | 株式会社サンギ | 口腔組成物 |
JP2975337B2 (ja) | 1997-02-20 | 1999-11-10 | 雪印乳業株式会社 | カルシウム複合体 |
AUPO566297A0 (en) * | 1997-03-13 | 1997-04-10 | University Of Melbourne, The | Calcium phosphopeptide complexes |
JP3742523B2 (ja) * | 1998-02-27 | 2006-02-08 | 雪印乳業株式会社 | 高分子型カルシウム・ホスホペプチド複合体 |
CN1201720C (zh) * | 1999-03-25 | 2005-05-18 | 卡德伯里亚当斯美国有限责任公司 | 口腔保健用的口香糖和糖果 |
FR2791573B1 (fr) | 1999-03-30 | 2003-04-11 | Pf Medicament | Utilisation d'un extrait de serenoa repens pour la fabrication d'un medicament destine au traitement du cancer de la prostate |
US6521215B2 (en) * | 1999-05-28 | 2003-02-18 | Devin Okay | Compositions and methods for tooth treatment |
US6685920B2 (en) | 1999-11-12 | 2004-02-03 | The Procter & Gamble Company | Method of protecting teeth against erosion |
GB9929919D0 (en) * | 1999-12-17 | 2000-02-09 | Hannah Research Inst The | Calcium phosphate nanoclusters and their applications |
JP2002338447A (ja) | 2001-05-15 | 2002-11-27 | Kuraray Co Ltd | 歯科用組成物 |
AUPR517701A0 (en) * | 2001-05-21 | 2001-06-14 | University Of Melbourne, The | Dental restorative materials |
WO2003059303A2 (en) * | 2002-01-03 | 2003-07-24 | The Procter & Gamble Company | Stable oral compositions comprising casein phosphopeptide complexes and fluoride |
CA2469431C (en) * | 2002-01-03 | 2009-05-26 | The Procter & Gamble Company | Stable oral compositions comprising casein phosphopeptide complexes and fluoride |
NZ522071A (en) | 2002-10-18 | 2005-07-29 | Patrick Joseph Silcock | Hydrolysed casein phosphoprotein preparations for bioactive metal ion delivery and teeth remineralisation |
JP4340069B2 (ja) | 2003-01-10 | 2009-10-07 | 雪印乳業株式会社 | カルシウム複合体の製造法 |
US20050089481A1 (en) | 2003-10-23 | 2005-04-28 | Gc Corporation | Composition for caries prevention |
US20060183081A1 (en) | 2004-09-27 | 2006-08-17 | Al Bevilacqua | Tooth bleaching system and method |
PT1888014E (pt) | 2005-06-07 | 2013-02-15 | Univ Melbourne | Mineralização dentária |
CN101208070B (zh) | 2005-06-24 | 2011-08-31 | 墨尔本大学 | 离子络合物 |
-
2005
- 2005-11-24 BR BRPI0517883A patent/BRPI0517883B8/pt active IP Right Grant
- 2005-11-24 MX MX2007006254A patent/MX2007006254A/es active IP Right Grant
- 2005-11-24 EP EP05804565.9A patent/EP1827366B1/en active Active
- 2005-11-24 US US11/720,285 patent/US8609071B2/en active Active
- 2005-11-24 WO PCT/AU2005/001781 patent/WO2006056013A1/en active Application Filing
- 2005-11-24 CN CN2005800465370A patent/CN101098675B/zh active Active
- 2005-11-24 JP JP2007541584A patent/JP5000525B2/ja active Active
- 2005-11-24 RU RU2007123603/15A patent/RU2404738C2/ru active
- 2005-11-24 AU AU2005309327A patent/AU2005309327B2/en active Active
- 2005-11-24 CA CA2589270A patent/CA2589270C/en active Active
- 2005-11-24 PL PL05804565T patent/PL1827366T3/pl unknown
- 2005-11-24 NZ NZ555335A patent/NZ555335A/en unknown
- 2005-11-24 EP EP17159493.0A patent/EP3192489A1/en active Pending
-
2013
- 2013-11-12 US US14/077,713 patent/US9295628B2/en active Active
-
2016
- 2016-03-03 US US15/059,878 patent/US9814662B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP1827366A4 (en) | 2010-05-26 |
EP1827366B1 (en) | 2017-03-15 |
US9814662B2 (en) | 2017-11-14 |
WO2006056013A1 (en) | 2006-06-01 |
US9295628B2 (en) | 2016-03-29 |
US20080075675A1 (en) | 2008-03-27 |
US8609071B2 (en) | 2013-12-17 |
CN101098675B (zh) | 2013-04-10 |
MX2007006254A (es) | 2007-09-07 |
PL1827366T3 (pl) | 2017-10-31 |
EP3192489A1 (en) | 2017-07-19 |
US20140079650A1 (en) | 2014-03-20 |
NZ555335A (en) | 2010-10-29 |
EP1827366A1 (en) | 2007-09-05 |
AU2005309327A1 (en) | 2006-06-01 |
CA2589270C (en) | 2014-07-15 |
AU2005309327B2 (en) | 2010-11-25 |
BRPI0517883A (pt) | 2008-10-21 |
CA2589270A1 (en) | 2006-06-01 |
JP5000525B2 (ja) | 2012-08-15 |
BRPI0517883B1 (pt) | 2015-06-23 |
JP2008521754A (ja) | 2008-06-26 |
CN101098675A (zh) | 2008-01-02 |
RU2404738C2 (ru) | 2010-11-27 |
US20160175226A1 (en) | 2016-06-23 |
RU2007123603A (ru) | 2008-12-27 |
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B07A | Technical examination (opinion): publication of technical examination (opinion) | ||
B09A | Decision: intention to grant | ||
B16A | Patent or certificate of addition of invention granted |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/11/2005, OBSERVADAS AS CONDICOES LEGAIS. |
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B16C | Correction of notification of the grant |
Free format text: REF. RPI 2320 DE 23/06/2015 QUANTO AO INVENTOR. |