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BRPI0403173A - polypeptide, nucleic acid molecule, vector, method for preparing a polypeptide, cell, use of polypeptide and / or nucleic acid and / or vector, pharmaceutical composition, and method of treating a human or animal patient - Google Patents

polypeptide, nucleic acid molecule, vector, method for preparing a polypeptide, cell, use of polypeptide and / or nucleic acid and / or vector, pharmaceutical composition, and method of treating a human or animal patient

Info

Publication number
BRPI0403173A
BRPI0403173A BRPI0403173-3A BRPI0403173A BRPI0403173A BR PI0403173 A BRPI0403173 A BR PI0403173A BR PI0403173 A BRPI0403173 A BR PI0403173A BR PI0403173 A BRPI0403173 A BR PI0403173A
Authority
BR
Brazil
Prior art keywords
polypeptide
vector
nucleic acid
preparing
human
Prior art date
Application number
BRPI0403173-3A
Other languages
Portuguese (pt)
Inventor
Richard Ross
Peter Artymiuk
Jon Sayers
Original Assignee
Asterion Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asterion Ltd filed Critical Asterion Ltd
Priority to BRPI0403173-3A priority Critical patent/BRPI0403173A/en
Publication of BRPI0403173A publication Critical patent/BRPI0403173A/en

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"POLIPEPTìDEO, MOLéCULA DE áCIDO NUCLEICO, VETOR, MéTODO PARA PREPARAR UM POLIPEPTìDEO, CéLULA, USO DO POLIPEPTìDEO E/OU DO áCIDO NUCLEICO E/OU DO VETOR, COMPOSIçãO FARMACêUTICA E MéTODO DE TRATAMENTO DE UM PACIENTE HUMANO OU ANIMAL". A invenção diz respeito ao fornecimento de polipeptídeos oligoméricos (dímeros, trímeros etc.) compreendendo os domínios de ligação de ligandos de citocinas que são ligadas através de moléculas ligadoras de polipeptídeos flexíveis. As moléculas ligadoras opcionalmente compreendem sítios sensíveis à protease para modular a liberação de citocinas biologicamente ativas quando administradas a um paciente humano ou animal."POLYPEPTIDE, NUCLEIC ACID MOLECULE, VECTOR, METHOD FOR PREPARING A POLYPEPTIDE, CELL, USE OF POLYPEPTIDE AND / OR VECTOR, PHARMACEUTICAL COMPOSITION, AND MATERIAL AND MATERIAL PATHUTICAL COMPOSITION" The invention relates to the provision of oligomeric polypeptides (dimers, trimers, etc.) comprising cytokine ligand binding domains that are linked via flexible polypeptide linker molecules. Linker molecules optionally comprise protease sensitive sites to modulate the release of biologically active cytokines when administered to a human or animal patient.

BRPI0403173-3A 2004-07-30 2004-07-30 polypeptide, nucleic acid molecule, vector, method for preparing a polypeptide, cell, use of polypeptide and / or nucleic acid and / or vector, pharmaceutical composition, and method of treating a human or animal patient BRPI0403173A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BRPI0403173-3A BRPI0403173A (en) 2004-07-30 2004-07-30 polypeptide, nucleic acid molecule, vector, method for preparing a polypeptide, cell, use of polypeptide and / or nucleic acid and / or vector, pharmaceutical composition, and method of treating a human or animal patient

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0403173-3A BRPI0403173A (en) 2004-07-30 2004-07-30 polypeptide, nucleic acid molecule, vector, method for preparing a polypeptide, cell, use of polypeptide and / or nucleic acid and / or vector, pharmaceutical composition, and method of treating a human or animal patient

Publications (1)

Publication Number Publication Date
BRPI0403173A true BRPI0403173A (en) 2006-03-21

Family

ID=36095939

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0403173-3A BRPI0403173A (en) 2004-07-30 2004-07-30 polypeptide, nucleic acid molecule, vector, method for preparing a polypeptide, cell, use of polypeptide and / or nucleic acid and / or vector, pharmaceutical composition, and method of treating a human or animal patient

Country Status (1)

Country Link
BR (1) BRPI0403173A (en)

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Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE A 4A ANUIDADE.

B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2082 DE 30/11/2010.