[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

BR9916887A - Uso de derivados de pirimidina - Google Patents

Uso de derivados de pirimidina

Info

Publication number
BR9916887A
BR9916887A BR9916887-1A BR9916887A BR9916887A BR 9916887 A BR9916887 A BR 9916887A BR 9916887 A BR9916887 A BR 9916887A BR 9916887 A BR9916887 A BR 9916887A
Authority
BR
Brazil
Prior art keywords
pyrimidine derivatives
substitutes
stroke
prevention
formula
Prior art date
Application number
BR9916887-1A
Other languages
English (en)
Inventor
Kurt Schellhaas
Wilfried Lubisch
Uta Holzenkamp
Dorothea Starck
Monika Knopp
Laszlo Szabo
Franz Emling
Francisco Javier Garcia-Ladona
Hans Peter Hofmann
Liliane Unger
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of BR9916887A publication Critical patent/BR9916887A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"USO DE DERIVADOS DE PIRIMIDINA". A invenção refere-se àutilização de derivados de pirimidina de fórmula (I) nos quais ossubstituintes possuem o significado citado na descrição, e aoemprego de seus sais fisiologicamente compatíveis para aprodução de medicamentos usados para a prevenção e otratamento de isquemia cerebral e de acidentes vascularescerebrais.
BR9916887-1A 1999-01-11 1999-12-24 Uso de derivados de pirimidina BR9916887A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19900545A DE19900545A1 (de) 1999-01-11 1999-01-11 Verwendung von Pyrimidinderivaten zur Prophylaxe und Therapie der zerebralen Ischämie
PCT/EP1999/010369 WO2000041695A1 (de) 1999-01-11 1999-12-24 Verwendung von pyrimidinderivaten zur prophylaxe und therapie der zerebralen ischämie

Publications (1)

Publication Number Publication Date
BR9916887A true BR9916887A (pt) 2001-11-20

Family

ID=7893836

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9916887-1A BR9916887A (pt) 1999-01-11 1999-12-24 Uso de derivados de pirimidina

Country Status (24)

Country Link
US (1) US6387912B1 (pt)
EP (1) EP1140096A1 (pt)
JP (1) JP2002534465A (pt)
KR (1) KR20010101442A (pt)
CN (1) CN1334732A (pt)
AU (1) AU2433800A (pt)
BG (1) BG105689A (pt)
BR (1) BR9916887A (pt)
CA (1) CA2359253A1 (pt)
CZ (2) CZ20012484A3 (pt)
DE (1) DE19900545A1 (pt)
HK (1) HK1042649A1 (pt)
HU (1) HUP0201149A3 (pt)
ID (1) ID30022A (pt)
IL (1) IL144146A0 (pt)
MX (1) MXPA01006967A (pt)
MY (1) MY133107A (pt)
NO (1) NO20013409L (pt)
NZ (1) NZ512767A (pt)
PL (1) PL348920A1 (pt)
SK (1) SK9692001A3 (pt)
TR (1) TR200102008T2 (pt)
WO (1) WO2000041695A1 (pt)
ZA (1) ZA200105475B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19900673A1 (de) 1999-01-11 2000-07-13 Basf Ag Verwendung von Bindungspartnern für 5-HT5-Rezeptoren zur Behandlung neurodegenerativer und neuropsychiatrischer Störungen
US6988199B2 (en) * 2000-07-07 2006-01-17 Message Secure Secure and reliable document delivery
JP4548882B2 (ja) * 1999-11-30 2010-09-22 興和創薬株式会社 ４，５，６，７−テトラヒドロチエノ〔２，３−ｃ〕ピリジン化合物
DE10031390A1 (de) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
DE10031389A1 (de) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidinderivate und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie
DE10259382A1 (de) * 2002-12-18 2004-07-01 Abbott Gmbh & Co. Kg 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-4-on-Derivate, ihre Herstellung und Verwendung
CA2685753A1 (en) * 2007-05-09 2008-11-20 Neuromed Pharmaceuticals Ltd. Bicyclic pyrimidine derivatives as calcium channel blockers
EP2471791B1 (en) * 2009-08-26 2014-11-12 Takeda Pharmaceutical Company Limited Fused heterocyclic ring derivative and use thereof
US11691971B2 (en) 2020-06-19 2023-07-04 Incyte Corporation Naphthyridinone compounds as JAK2 V617F inhibitors
US11753413B2 (en) 2020-06-19 2023-09-12 Incyte Corporation Substituted pyrrolo[2,1-f][1,2,4]triazine compounds as JAK2 V617F inhibitors
JP2023533724A (ja) 2020-07-02 2023-08-04 インサイト・コーポレイション Ｊａｋ２ ｖ６１７ｆ阻害剤としての三環式尿素化合物
US11767323B2 (en) 2020-07-02 2023-09-26 Incyte Corporation Tricyclic pyridone compounds as JAK2 V617F inhibitors
WO2022046989A1 (en) 2020-08-27 2022-03-03 Incyte Corporation Tricyclic urea compounds as jak2 v617f inhibitors
WO2022140231A1 (en) 2020-12-21 2022-06-30 Incyte Corporation Deazaguaine compounds as jak2 v617f inhibitors
EP4298099A1 (en) 2021-02-25 2024-01-03 Incyte Corporation Spirocyclic lactams as jak2 v617f inhibitors
AU2023235313A1 (en) 2022-03-17 2024-10-03 Incyte Corporation Tricyclic urea compounds as jak2 v617f inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4670560A (en) * 1986-04-28 1987-06-02 Ortho Pharmaceutical Corporation Thienopyrimidine-2,4-dione derivatives and intermediates thereof
DE19636769A1 (de) 1996-09-10 1998-03-12 Basf Ag 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19724980A1 (de) 1997-06-13 1998-12-17 Basf Ag 3-Substituierte 3,4-Dihydro-thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
DE19724979A1 (de) 1997-06-13 1998-12-17 Basf Ag 3-substituierte Pyrido [3,4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
IL144146A0 (en) 2002-05-23
US6387912B1 (en) 2002-05-14
CN1334732A (zh) 2002-02-06
HUP0201149A3 (en) 2003-07-28
HUP0201149A2 (hu) 2002-07-29
BG105689A (en) 2002-02-28
HK1042649A1 (zh) 2002-08-23
NZ512767A (en) 2003-05-30
NO20013409L (no) 2001-08-30
KR20010101442A (ko) 2001-11-14
PL348920A1 (en) 2002-06-17
MXPA01006967A (es) 2002-04-10
JP2002534465A (ja) 2002-10-15
TR200102008T2 (tr) 2001-12-21
ZA200105475B (en) 2002-10-03
DE19900545A1 (de) 2000-07-13
AU2433800A (en) 2000-08-01
ID30022A (id) 2001-11-01
CZ20012485A3 (cs) 2002-04-17
SK9692001A3 (en) 2002-05-09
WO2000041695A1 (de) 2000-07-20
MY133107A (en) 2007-10-31
CA2359253A1 (en) 2000-07-20
NO20013409D0 (no) 2001-07-10
EP1140096A1 (de) 2001-10-10
CZ20012484A3 (cs) 2002-05-15

Similar Documents

Publication Publication Date Title
BR9916887A (pt) Uso de derivados de pirimidina
BR9911160A (pt) Ciclosporinas
RS50876B (sr) Upotreba flibanserina u lečenju seksualnih poremećaja
ECSP034774A (es) Pirazolopirimmidinas como agentes terapeuticos
ECSP034773A (es) Pirazolopirimmidinas como agentes terapeuticos
GT200600496A (es) Sales, profarmacos y formulaciones de 1-[5-(4-amino-7-isopropil-7h-pirrolo[2,3-d]piirimidin-5-carbonil)-2-metoxi-feil]-3-(2,4-dicloro-fenil)-urea.
BR0111263A (pt) Derivados de 2-aminocarbonil-9h-purina
BR0215312A (pt) Uso de um composto, método para inibir a aurora quinase em um animal de sangue quente, composto, composição farmacêutica, e, processo para a preparação de um composto
BR9915967A (pt) Derivados de propanolamina substituìdos por arila, proceso para sua preparação, medicamentos contendo estes compostos e seu uso
YU92501A (sh) Levodop/karbidop/entakapon farmaceutski preparat
ES2177346T3 (es) Formulaciones de ranolazina de liberacion lenta.
BR9713363A (pt) Epotilonas c, d, e e f, preparação e composições
TR200200579T2 (tr) Amino-tirazolpiridin türevleri.
BR0213562A (pt) Benzimidazóis e análogos e seu uso como inibidores de cinases de proteìna
AU2134402A (en) Antiviral agents
BR0210122A (pt) Composto ou um sal farmaceuticamente aceitável do mesmo, método para o tratamento ou prevenção de uma doença, uso do composto ou de seu sal, e, método para preparar o mesmo
BR0015322A (pt) Derivados de indeno-, nafto- e benzociclohepta-dihidrotiazol, sua preparação e seu emprego como medicamentos anoréticos
BR0211063A (pt) Sais de derivados anticonvulsivantes
BR0011700A (pt) Dinitrilas de ácido arilmalÈnico substituìdo como intermediários para a preparação de herbicidas
BR0101230A (pt) Processo para a preparação de11-amino-3-cloro-6,11-diidro-5-5-dioxo-6-metil-dibenzo[c,f][1,2]tiazepina e aplicação para a sìntese detianeptina
BR0115045A (pt) Compostos, processo para sua preparação, composição farmacêutica que compreende os mesmos, sua utilização, processo para o tratamento e profilaxia de artrite, diabetes, distúrbios alimentares e obesidade
BR9914266A (pt) Derivados de propanolamina substituìdos por heterociclos, processos para a sua preparação, medicamentos contendo estes compostos e seu emprego
BR0012169A (pt) Dihidrobenzodiazepinas e seu uso no tratamento de dislipidemia
BR0116060A (pt) Composição farmacêutica de dronedarona para administração parenteral
BR9814495A (pt) Composto, processo para prepará-lo, uso do mesmo, composição farmacêutica, e, processo

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 4O, 5O, 6O E 7O ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1913 DE 04/09/2007.