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BR9915897A - Nucleic acid transfer agents, composition, use of a transfer agent and processes for the treatment of human or animal body and transfer of nucleic acids. - Google Patents

Nucleic acid transfer agents, composition, use of a transfer agent and processes for the treatment of human or animal body and transfer of nucleic acids.

Info

Publication number
BR9915897A
BR9915897A BR9915897-3A BR9915897A BR9915897A BR 9915897 A BR9915897 A BR 9915897A BR 9915897 A BR9915897 A BR 9915897A BR 9915897 A BR9915897 A BR 9915897A
Authority
BR
Brazil
Prior art keywords
transfer
nucleic acid
nucleic acids
human
composition
Prior art date
Application number
BR9915897-3A
Other languages
Portuguese (pt)
Inventor
Jean Herscovici
Hans Hofland
Christophe Jacopin
Daniel Sherman
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9815309A external-priority patent/FR2786700B1/en
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of BR9915897A publication Critical patent/BR9915897A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

"AGENTES DE TRANSFERêNCIA DE áCIDOS NUCLEICOS, COMPOSIçãO, UTILIZAçãO DE UM AGENTE DE TRANSFERêNCIA E PROCESSOS DE TRATAMENTO DE CORPO HUMANO OU ANIMAL E DE TRANSFERêNCIA DE áCIDOS NUCLEICOS". A presente invenção refere-se a novos agentes de transferência, as composições contendo os mesmos e suas utilizações para a transferência in vitro, in vivo ou ex vivo de ácidos nucleicos nas células. Mais precisamente, a presente invenção refere-se a novos agentes de transferência de ácidos nucleicos que compreendem um espaçador hidrófobo ligado quimicamente de um lado a um policátion e por outro lado a pelo menos um substituinte hidrófilo."NUCLEIC ACID TRANSFER AGENTS, COMPOSITION, USE OF A TRANSFER AGENT AND HUMAN OR ANIMAL BODY TREATMENT PROCESSES AND TRANSFER OF NUCLEIC ACIDS". The present invention relates to new transfer agents, the compositions containing them and their uses for the in vitro, in vivo or ex vivo transfer of nucleic acids in cells. More precisely, the present invention relates to new nucleic acid transfer agents that comprise a hydrophobic spacer chemically bonded on the one hand to a polycation and on the other hand to at least one hydrophilic substituent.

BR9915897-3A 1998-12-03 1999-12-02 Nucleic acid transfer agents, composition, use of a transfer agent and processes for the treatment of human or animal body and transfer of nucleic acids. BR9915897A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9815309A FR2786700B1 (en) 1998-12-03 1998-12-03 NOVEL NUCLEIC ACID TRANSFERS, COMPOSITIONS CONTAINING THEM, AND USES THEREOF
US11718499P 1999-01-26 1999-01-26
PCT/FR1999/002995 WO2000032803A2 (en) 1998-12-03 1999-12-02 Novel nucleic acid transferring agents, compositions containing them and uses

Publications (1)

Publication Number Publication Date
BR9915897A true BR9915897A (en) 2001-08-21

Family

ID=26234691

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9915897-3A BR9915897A (en) 1998-12-03 1999-12-02 Nucleic acid transfer agents, composition, use of a transfer agent and processes for the treatment of human or animal body and transfer of nucleic acids.

Country Status (13)

Country Link
EP (1) EP1137793A2 (en)
JP (1) JP2002531468A (en)
KR (1) KR20010101116A (en)
CN (1) CN1348498A (en)
AU (1) AU772033B2 (en)
BR (1) BR9915897A (en)
CA (1) CA2353576A1 (en)
CZ (1) CZ20011909A3 (en)
HU (1) HUP0200345A3 (en)
IL (1) IL142704A0 (en)
NO (1) NO20012684L (en)
PL (1) PL348513A1 (en)
WO (1) WO2000032803A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2805271B1 (en) * 2000-02-18 2002-04-26 Aventis Pharma Sa PROCESS FOR THE PREPARATION OF FUNCTIONALIZED POLYALKYLENIMINES, COMPOSITIONS CONTAINING THEM AND THEIR USES
JP2005080598A (en) * 2003-09-10 2005-03-31 Japan Science & Technology Agency Method for introducing plasmid DNA using β-1,3-glucan derivative
CN103820320B (en) * 2013-06-25 2017-03-15 宁波有成生物医药科技有限公司 Liquid protected by a kind of non-jelly type RNA

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996021036A2 (en) * 1994-12-30 1996-07-11 Chiron Viagene, Inc. Nucleic acid condensing agents with reduced immunogenicity
FR2730637B1 (en) * 1995-02-17 1997-03-28 Rhone Poulenc Rorer Sa PHARMACEUTICAL COMPOSITION CONTAINING NUCLEIC ACIDS, AND USES THEREOF
US5948681A (en) * 1996-08-14 1999-09-07 Children's Hospital Of Philadelphia Non-viral vehicles for use in gene transfer

Also Published As

Publication number Publication date
AU772033B2 (en) 2004-04-08
CN1348498A (en) 2002-05-08
NO20012684D0 (en) 2001-05-31
CA2353576A1 (en) 2000-06-08
JP2002531468A (en) 2002-09-24
PL348513A1 (en) 2002-06-03
HUP0200345A3 (en) 2003-12-29
WO2000032803A2 (en) 2000-06-08
AU1564600A (en) 2000-06-19
WO2000032803A3 (en) 2000-10-12
IL142704A0 (en) 2002-03-10
NO20012684L (en) 2001-07-30
KR20010101116A (en) 2001-11-14
HUP0200345A2 (en) 2002-05-29
CZ20011909A3 (en) 2001-09-12
EP1137793A2 (en) 2001-10-04

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1913 DE 04/09/2007.