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BR9702362A - Novas fomrulações lìquidas estáveis à base de paracetamol e seu modo de preparação. - Google Patents

Novas fomrulações lìquidas estáveis à base de paracetamol e seu modo de preparação.

Info

Publication number
BR9702362A
BR9702362A BR9702362-0A BR9702362A BR9702362A BR 9702362 A BR9702362 A BR 9702362A BR 9702362 A BR9702362 A BR 9702362A BR 9702362 A BR9702362 A BR 9702362A
Authority
BR
Brazil
Prior art keywords
paracetamol
preparation
new stable
stable liquid
added
Prior art date
Application number
BR9702362-0A
Other languages
English (en)
Inventor
Francois Dietlin
Dani Le Fredj
Original Assignee
Scr Pharmatop
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9494820&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9702362(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Scr Pharmatop filed Critical Scr Pharmatop
Publication of BR9702362A publication Critical patent/BR9702362A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"NOVAS FORMULAçõES LìQUIDAS ESTáVEIS à BASE DE PARACETAMOL E SEU MODO DE PREPARAçãO". A invenção se refere ao campo da química terapêutica e, mais especialmente, ao da farmácia galênica. Também por objeto, mais particularmente, novas formulações à base de paracetamol, estáveis, incluindo paracetamol em solução em um solvente aquoso, adicionado de um tampão de pH 4 a 8 e de um agente captador de radicais livres, tendo-se tomado o cuidado de borbulhar no solvente aquoso um gás inerte, insolúvel na água, para remover o oxigênio do meio. As preparações de acordo com a invenção podem ser adicionadas, além disso, de um agente anódino de ação central ou de ação periférica. Utilização sob forma de preparações injetáveis para o tratamento da dor.
BR9702362-0A 1996-08-05 1997-08-05 Novas fomrulações lìquidas estáveis à base de paracetamol e seu modo de preparação. BR9702362A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9609858A FR2751875B1 (fr) 1996-08-05 1996-08-05 Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation
PCT/FR1997/001452 WO1998005314A1 (fr) 1996-08-05 1997-08-05 Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation

Publications (1)

Publication Number Publication Date
BR9702362A true BR9702362A (pt) 1999-12-28

Family

ID=9494820

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9702362-0A BR9702362A (pt) 1996-08-05 1997-08-05 Novas fomrulações lìquidas estáveis à base de paracetamol e seu modo de preparação.

Country Status (23)

Country Link
US (1) US6028222A (pt)
EP (1) EP0858329B1 (pt)
JP (2) JP5060681B2 (pt)
KR (1) KR100521235B1 (pt)
CN (1) CN1133426C (pt)
AP (1) AP957A (pt)
AT (1) ATE241972T1 (pt)
AU (1) AU742576B2 (pt)
BR (1) BR9702362A (pt)
CA (1) CA2233924C (pt)
CZ (1) CZ298427B6 (pt)
DE (1) DE69722580T2 (pt)
DK (1) DK0858329T3 (pt)
ES (1) ES2201316T3 (pt)
FR (1) FR2751875B1 (pt)
HU (1) HU226117B1 (pt)
MX (1) MX9802734A (pt)
NZ (1) NZ330136A (pt)
OA (1) OA10678A (pt)
PL (1) PL193104B1 (pt)
PT (1) PT858329E (pt)
RU (1) RU2192249C2 (pt)
WO (1) WO1998005314A1 (pt)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6160020A (en) * 1996-12-20 2000-12-12 Mcneill-Ppc, Inc. Alkali metal and alkaline-earth metal salts of acetaminophen
US8524277B2 (en) 1998-03-06 2013-09-03 Alza Corporation Extended release dosage form
US6245357B1 (en) * 1998-03-06 2001-06-12 Alza Corporation Extended release dosage form
FR2779061B1 (fr) * 1998-04-14 2004-08-20 Pharmatop Nouveau procede de stabilisation de composes phenoliques et les compositions pharmaceutiques en resultant
IT1301976B1 (it) * 1998-07-31 2000-07-20 Angelini Ricerche Spa Composizione farmaceutica iniettabile a base di paracetamolo
JP2003500302A (ja) * 1999-05-28 2003-01-07 ノバルティス アクチエンゲゼルシャフト 医薬品のパッケージおよびそのパッケージの滅菌方法
DE19932157A1 (de) * 1999-07-13 2001-01-18 Pharmasol Gmbh Verfahren zur schonenden Herstellung von hochfeinen Mikropartikeln und Nanopartikeln
US6334859B1 (en) 1999-07-26 2002-01-01 Zuli Holdings Ltd. Subcutaneous apparatus and subcutaneous method for treating bodily tissues with electricity or medicaments
IT1313579B1 (it) * 1999-07-30 2002-09-09 Acraf Composizione farmaceutica liquida a base di paracetamolo.
GB0006897D0 (en) * 2000-03-23 2000-05-10 Smithkline Beecham Plc Medicaments
FR2809619B1 (fr) * 2000-06-06 2004-09-24 Pharmatop Nouvelles formulations aqueuses de principes actifs sensibles a l'oxydation et leur procede d'obtention
AU2006203741B2 (en) * 2000-06-06 2009-11-05 Scr Pharmatop Method for obtaining aqueous formulations with active principles susceptible to oxidation and the aqueous solutions thus obtained
DE10112325A1 (de) * 2001-03-13 2002-10-02 Fresenius Kabi De Gmbh Lagerstabile Fertiginfusionslösungen des Paracetamols
ITMI20012135A1 (it) * 2001-10-16 2003-04-16 Bioren S A Soluzioni iniettabili pronte all'uso di paracetamolo
WO2003051398A1 (en) * 2001-12-18 2003-06-26 Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. Parenteral composition of paracetamol
FR2851164B1 (fr) 2003-02-14 2005-04-22 Xuan Tho Nguyen Formulation liquide injectable de paracetamol
BG65674B1 (bg) * 2003-07-10 2009-06-30 Нихфи Ад Течна форма на комбинирано лекарствено средство за лечение на простудни и грипни заболявания
DK1574221T3 (da) * 2004-03-10 2007-07-16 Shimoda Biotech Pty Ltd Stabile, injicérbare diclofenacsammensætninger
US20060205752A1 (en) * 2005-03-14 2006-09-14 Keith Whitehead Stabilized hydrocodone pharmaceutical compositions with ethylenediaminetetraacetic acid
DE102005037653A1 (de) * 2005-08-05 2007-02-15 Theraselect Gmbh Stabile, flüssige Formulierung von Paracetamol
US20070098790A1 (en) * 2005-10-31 2007-05-03 David Jiang Nutritional supplement for the enhancement of the health of the liver
FR2894154B1 (fr) * 2005-12-06 2008-03-14 Pharmatop Scr Nouveau procede de stabilisation de substances minerales ou organiques sensibles a l'oxydation.
KR20170123724A (ko) * 2006-03-28 2017-11-08 자블린 파머슈티칼스 인코포레이티드 저 투여량의 디클로페낙 및 베타-사이클로덱스트린 제형
US20070249727A1 (en) 2006-04-21 2007-10-25 The Proctor & Gamble Company Compositions and kits useful for treatment of respiratory illness
US10022339B2 (en) 2006-04-21 2018-07-17 The Procter & Gamble Company Compositions and methods useful for treatment of respiratory illness
CA2628806C (en) * 2006-07-18 2012-08-21 Genfarma Laboratorio S.L. Injectable liquid paracetamol formulation
EP1992334A1 (en) * 2007-05-08 2008-11-19 Docpharma NV/SA Storage-stable formulation of oxidation-sensitive phenolic drug, especially paracetamol, comprises aqueous drug solution deoxygenated by a temperature-controlled manufacturing process of the formulation
WO2009047634A2 (en) * 2007-06-18 2009-04-16 Combino Pharm, S.L. Aqueous formulations of acetaminophen for injection
WO2009081283A2 (en) * 2007-06-18 2009-07-02 Combino Pharm, S.L. Aqueous formulations of acetaminophen for injection
JP5909750B2 (ja) 2007-11-13 2016-04-27 マリンクロット アイピー 低用量静脈内アセトアミノフェン
US20110015273A1 (en) * 2008-01-17 2011-01-20 Rajnarayana Kandhagatla Stable pharmaceutical aqueous compositions
FR2926992B1 (fr) * 2008-02-06 2011-01-14 Moly Pharma Formulation d'une solution de paracetamol injectable,procede de preparation et de conditionnement d'une telle solution et dispositif de conditionnement d'une telle solution
WO2009157010A1 (en) * 2008-06-25 2009-12-30 Akums Drugs And Pharmaceuticals Limited An intravenous drug delivery system
WO2009157009A1 (en) * 2008-06-25 2009-12-30 Akums Drugs And Pharmaceuticals Limited An intravenous drug delivery system
EP2243477A1 (de) 2009-04-22 2010-10-27 Fresenius Kabi Deutschland GmbH Paracetamol zur parenteralen Verabreichung
EP2453743B1 (en) * 2009-07-15 2017-04-12 The Board of Trustees of The Leland Stanford Junior University N-acetyl cysteine compositions and their use in improving the therapeutic efficacy of acetaminophen
EP2277546B1 (en) 2009-07-23 2015-07-15 Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. Stable ready to use injectable paracetamol formulation
US8404748B2 (en) * 2009-08-13 2013-03-26 Neogen N.V. Storage-stable formulation of paracetamol in aqueous solution
EP2464332B1 (en) 2009-08-13 2016-03-02 Neogen N.V. Storage-stable formulation of paracetamol in aqueous solution
FR2950533B1 (fr) * 2009-09-28 2012-01-13 Maco Pharma Sa Formulation liquide, stable, prete a l'emploi de ketoprofene
EP2308463A1 (en) * 2009-10-12 2011-04-13 EMP Pharma GmbH Aqueous acetaminophen compositions and method of preparation
CN102711726A (zh) 2009-12-10 2012-10-03 特克尼梅德医疗技术股份公司 用于制备扑热息痛稳定液体制剂的方法和组合物
RU2446799C2 (ru) * 2010-01-22 2012-04-10 Анатолий Брониславович Гаврилов Антиоксидантная композиция
US20110207824A1 (en) * 2010-02-25 2011-08-25 Moly Pharma Formulation of an injectable paracetamol solution, method for preparing and packaging such a solution and device for packaging such a solution
PT2377516E (pt) * 2010-04-14 2012-07-02 Braun Melsungen Ag Composição acetaminofeno
GR1007315B (el) * 2010-04-19 2011-06-14 Uni-Pharma Κλεων Τσετης Φαρμακευτικα Εργαστηρια Αβεε Με Δ.Τ. Uni-Pharma Abee, Υγρομορφη παρεντερικης χορηγησης συνθεση που περιλαμβανει τραμαδολη hci και παρακεταμολη
DK2389923T3 (da) * 2010-05-19 2013-03-18 Uni Pharma Kleon Tsetis Pharmaceutical Lab S A Stabil klar til brug injicerbar paracetamol-formulering
EP2389931A1 (en) 2010-05-21 2011-11-30 Raw Materials Internatinal LLC Pharmaceutical aqueous compositions comprising lipoic acid as an antioxidant
MX2012014800A (es) * 2010-06-30 2013-01-29 Troikaa Pharmaceuticals Ltd Composiciones farmaceuticas que comprenden paracetamol y proceso para preparar el mismo.
EP2649993B1 (en) * 2010-12-09 2017-04-05 Maruishi Pharmaceutical Co., Ltd. Stabilizer of acetaminophen
CN102600068A (zh) * 2011-01-24 2012-07-25 联康药业克雷恩特塞提斯制药实验室有限责任公司 稳定即用的可注射扑热息痛制剂
AU2011200289B2 (en) * 2011-01-24 2016-10-13 Ioulia Tseti Stable ready to use injectable paracetamol formulation
EP2672955A1 (en) * 2011-02-10 2013-12-18 Neogen N.V. Storage-stable formulation of paracetamol in aqueous solution
ES2414557B1 (es) 2012-01-16 2014-06-10 Novocat Farma, S.A. Composición acuosa de paracetamol para inyección
ITMI20121154A1 (it) 2012-06-29 2013-12-30 Sint Sa Soluzione iniettabile di acetaminofene per la somministrazione spinale
US8568747B1 (en) 2012-10-05 2013-10-29 Silvergate Pharmaceuticals, Inc. Enalapril compositions
ZA201300398B (en) 2012-11-27 2013-09-25 Genfarma Laboratories S L Injectable liquid formulation of the combination of tramadol and paracetamol
EP3086793B1 (en) 2013-12-24 2022-05-11 Virginia Commonwealth University Use of oxygenated cholesterol sulfates (ocs) for the treatment of kidney dysfunction
BR102014005885B1 (pt) 2014-03-13 2021-04-13 Biotec Biológica Indústria Farmacêutica Ltda E.P.P Formulação farmacêutica líquida injetável estável de paracetamol em bolsa plástica pronta para uso
US20170202793A1 (en) 2014-07-25 2017-07-20 Terumo Kabushiki Kaisha Packaged acetaminophen injection solution preparation
US20180000940A1 (en) 2014-12-20 2018-01-04 Troikaa Pharmaceuticals Limited Injectable formulations of paracetamol
US9463183B1 (en) 2015-10-30 2016-10-11 Silvergate Pharmaceuticals, Inc. Lisinopril formulations
BR112018014354A2 (pt) * 2016-02-05 2018-12-18 Innopharma Inc processo de fabricação de uma bolsa de infusão estável, pronta para uso para uma formulação sensível à oxidação
US9669008B1 (en) 2016-03-18 2017-06-06 Silvergate Pharmaceuticals, Inc. Enalapril formulations
CA3037810A1 (en) * 2016-09-23 2018-03-29 Grunenthal Gmbh Stable formulation for parenteral administration of tapentadol
US11040007B2 (en) * 2017-01-24 2021-06-22 Woosung Pharmaceutical Co., Ltd. Injection composition containing acetaminophen
CA3051467C (en) 2017-01-30 2022-11-29 Nevakar, Inc Norepinephrine compositions and methods therefor
WO2018192664A1 (en) * 2017-04-20 2018-10-25 Hyloris Developments Sa METHOD FOR PREPARING A COMPOSITION WITH A LOW DISSOLVED OXYGEN CONTENT, COMPRISING ACETAMINOPHEN, AND OPTIONALLY ONE OR MORE NSAIDs, AND A COMPOSITION OBTAINED THEREOF
RU2737852C2 (ru) * 2017-12-28 2020-12-03 Беккер Герман Петрович Способ получения лекарственного средства на основе олигопептида аллоферона-1, имеющего противовирусную и иммуномодулирующую направленность, и лекарственное средство увеличенного срока хранения, полученное с его помощью
CN115385818B (zh) * 2022-09-01 2023-09-29 江苏海洋大学 一种扑热息痛杂质及制备方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314989A (en) * 1980-05-07 1982-02-09 Rosen Gerald M Methionine sulfoxide amflioration of acetaminophen toxicity
RO82841A2 (ro) * 1981-08-04 1983-11-01 Intreprinderea De Medicamente "Biofarm",Ro Suspensie cu paracetamol
US4727064A (en) * 1984-04-25 1988-02-23 The United States Of America As Represented By The Department Of Health And Human Services Pharmaceutical preparations containing cyclodextrin derivatives
US4855326A (en) * 1987-04-20 1989-08-08 Fuisz Pharmaceutical Ltd. Rapidly dissoluble medicinal dosage unit and method of manufacture
FR2646773B1 (fr) * 1989-05-12 1994-05-13 Chauvin Sa Laboratoire Composition pharmaceutique a base de paracetamol
JPH0714872B2 (ja) * 1990-02-06 1995-02-22 昭和薬品化工株式会社 シロップ剤組成物
JPH0672897A (ja) * 1991-03-27 1994-03-15 Cullim & Assoc Inc 月経前の及び月経の不快な諸症状を軽減するための組成物
US5252313A (en) * 1991-12-20 1993-10-12 Colgate-Palmolive Company Visually clear gel dentifrice
US5272137A (en) * 1992-02-14 1993-12-21 Mcneil-Pfc, Inc. Aqueous pharmaceutical suspension for pharmaceutical actives
US5474757A (en) * 1992-10-16 1995-12-12 Rutgers University Prevention of acetaminophen overdose toxicity with organosulfur compounds
FI941777A (fi) * 1993-04-16 1994-10-17 Mcneil Ppc Inc Vesipitoinen farmaseuttinen suspensio ja menetelmä sen valmistamiseksi
DE4327462A1 (de) * 1993-08-16 1995-02-23 Carl Heinrich Dr Weischer Neue N-Acetyl-p-Aminophenol-Derivate zur Bekämpfung von Schmerzzuständen
JPH07206689A (ja) * 1994-01-21 1995-08-08 Barnett Lab Ltd 治療組成物および宿酔の治療のためのこの組成物の使用法
MX9602955A (es) * 1994-01-24 1997-06-28 Procter & Gamble Procedimiento para solubizar activos farmaceuticos dificilmente solubles.
US5510389A (en) * 1994-03-02 1996-04-23 The Procter & Gamble Company Concentrated acetaminophen solution compositions
JPH09286724A (ja) * 1996-04-19 1997-11-04 Takeda Chem Ind Ltd 経口用安定液剤

Also Published As

Publication number Publication date
AU742576B2 (en) 2002-01-10
KR100521235B1 (ko) 2006-01-27
MX9802734A (es) 1998-11-30
CN1133426C (zh) 2004-01-07
HUP9901893A3 (en) 2000-06-28
HU226117B1 (en) 2008-04-28
ES2201316T3 (es) 2004-03-16
EP0858329A1 (fr) 1998-08-19
JP2010163462A (ja) 2010-07-29
CZ104898A3 (cs) 1998-09-16
FR2751875B1 (fr) 1998-12-24
CN1204960A (zh) 1999-01-13
AP957A (en) 2001-04-12
PT858329E (pt) 2003-09-30
DE69722580T2 (de) 2004-04-29
DE69722580D1 (de) 2003-07-10
OA10678A (fr) 2002-11-20
PL326069A1 (en) 1998-08-17
AU3945197A (en) 1998-02-25
FR2751875A1 (fr) 1998-02-06
JPH11514013A (ja) 1999-11-30
PL193104B1 (pl) 2007-01-31
AP9801223A0 (en) 1998-06-30
JP5060681B2 (ja) 2012-10-31
DK0858329T3 (da) 2003-09-29
KR19990063978A (ko) 1999-07-26
US6028222A (en) 2000-02-22
CA2233924A1 (fr) 1998-02-12
CZ298427B6 (cs) 2007-10-03
NZ330136A (en) 2000-03-27
ATE241972T1 (de) 2003-06-15
JP5122604B2 (ja) 2013-01-16
WO1998005314A1 (fr) 1998-02-12
RU2192249C2 (ru) 2002-11-10
HUP9901893A2 (hu) 1999-09-28
EP0858329B1 (fr) 2003-06-04
CA2233924C (fr) 2012-08-21

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