BR9611619B1 - ciclopeptolìdeos e composição farmacêutica que os contêm. - Google Patents

ciclopeptolìdeos e composição farmacêutica que os contêm.

Info

Publication number: BR9611619B1
Authority: BR; Brazil
Prior art keywords: cyclopeptides; pharmaceutical composition; composition containing; pharmaceutical; composition
Prior art date: 1995-11-21

Application number

BRPI9611619-6A

Other languages

English (en)

Portuguese (pt)

Other versions

BR9611619A (pt

Inventor

Michael Dreyfuss

Theodor Fehr

Carolyn Ann Foster

Dieter Geyl

Berndt Oberhauser

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-11-21

Filing date

1996-11-20

Publication date

2010-08-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27267982&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9611619(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-11-21 Priority claimed from GBGB9523744.2A external-priority patent/GB9523744D0/en

1996-03-01 Priority claimed from GBGB9604406.0A external-priority patent/GB9604406D0/en

1996-07-04 Priority claimed from GBGB9613990.2A external-priority patent/GB9613990D0/en

1996-11-20 Application filed filed Critical

1999-03-30 Publication of BR9611619A publication Critical patent/BR9611619A/pt

2010-08-10 Publication of BR9611619B1 publication Critical patent/BR9611619B1/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/15—Depsipeptides; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
General Engineering & Computer Science (AREA)
Pulmonology (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Diabetes (AREA)
Biomedical Technology (AREA)
Virology (AREA)
Tropical Medicine & Parasitology (AREA)
Mycology (AREA)
Botany (AREA)
Biophysics (AREA)
Hematology (AREA)
Obesity (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Pain & Pain Management (AREA)

BRPI9611619-6A 1995-11-21 1996-11-20 ciclopeptolìdeos e composição farmacêutica que os contêm. BR9611619B1 (pt)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GBGB9523744.2A GB9523744D0 (en)	1995-11-21	1995-11-21	Organic compounds
GBGB9604406.0A GB9604406D0 (en)	1996-03-01	1996-03-01	Organic compounds
GBGB9613990.2A GB9613990D0 (en)	1996-07-04	1996-07-04	Organic compounds
PCT/EP1996/005123 WO1997019104A1 (en)	1995-11-21	1996-11-20	Cyclopeptolides

Publications (2)

Publication Number	Publication Date
BR9611619A BR9611619A (pt)	1999-03-30
BR9611619B1 true BR9611619B1 (pt)	2010-08-10

Family

ID=27267982

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI9611619-6A BR9611619B1 (pt)	1995-11-21	1996-11-20	ciclopeptolìdeos e composição farmacêutica que os contêm.

Country Status (27)

Country	Link
US (1)	US6011136A (de)
EP (1)	EP0866801B1 (de)
JP (1)	JP3463691B2 (de)
KR (1)	KR19990071533A (de)
CN (1)	CN1125079C (de)
AR (1)	AR012286A1 (de)
AT (1)	ATE240972T1 (de)
AU (1)	AU712900B2 (de)
BR (1)	BR9611619B1 (de)
CA (1)	CA2237157C (de)
CO (1)	CO4770985A1 (de)
CZ (1)	CZ154998A3 (de)
DE (1)	DE69628323T2 (de)
ES (1)	ES2200079T3 (de)
HU (1)	HUP9903810A3 (de)
IL (1)	IL124310A0 (de)
MX (1)	MX9804048A (de)
MY (1)	MY115877A (de)
NO (1)	NO982280D0 (de)
NZ (1)	NZ322909A (de)
PE (1)	PE22998A1 (de)
PL (1)	PL186010B1 (de)
RU (1)	RU2171260C2 (de)
SK (1)	SK65698A3 (de)
TR (1)	TR199800897T2 (de)
TW (1)	TW450978B (de)
WO (1)	WO1997019104A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2002034283A2 (en) *	2000-10-27	2002-05-02	Novartis Ag	Vegh inhibitors and their use
MXPA06010587A (es) *	2004-03-17	2007-03-29	Chiron Corp	Tratamiento de neumonia severa adquirida en comunidad por administracion del inhibidor de la via del factor tisular (tfpi).
US11339193B2 (en)	2018-03-29	2022-05-24	Kezar Life Sciences	CDP protein secretion inhibitors
CN118319952B (zh) *	2024-04-09	2024-09-20	青岛西凯生物技术有限公司	一种修复子宫内膜损伤的干细胞制剂及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3832059A1 (de) *	1988-09-21	1990-03-29	Howaldtswerke Deutsche Werft	Tauchtiefengesteuerte ausblasventil-einrichtung
DE3832362A1 (de) *	1988-09-23	1990-03-29	Sandoz Ag	Neue cyclopeptolide, verfahren zu ihrer herstellung und ihre verwendung
AT396108B (de) *	1991-08-21	1993-06-25	Biochemie Gmbh	Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten
JPH07109299A (ja) *	1993-10-13	1995-04-25	Shionogi & Co Ltd	抗ｈｉｖ物質ペスタヒビン及びその誘導体
ES2142490T3 (es) *	1994-07-27	2000-04-16	Novartis Ag	Ciclopeptolidos.
US20040219569A1 (en) *	1999-07-06	2004-11-04	Fruma Yehiely	Gene identification method

1996
- 1996-11-11 US US09/068,915 patent/US6011136A/en not_active Expired - Fee Related
- 1996-11-18 AR ARP960105235A patent/AR012286A1/es not_active Application Discontinuation
- 1996-11-19 MY MYPI96004794A patent/MY115877A/en unknown
- 1996-11-19 PE PE1996000830A patent/PE22998A1/es not_active Application Discontinuation
- 1996-11-20 CN CN96198477A patent/CN1125079C/zh not_active Expired - Fee Related
- 1996-11-20 SK SK656-98A patent/SK65698A3/sk unknown
- 1996-11-20 PL PL96326755A patent/PL186010B1/pl unknown
- 1996-11-20 BR BRPI9611619-6A patent/BR9611619B1/pt not_active IP Right Cessation
- 1996-11-20 CA CA002237157A patent/CA2237157C/en not_active Expired - Fee Related
- 1996-11-20 HU HU9903810A patent/HUP9903810A3/hu unknown
- 1996-11-20 WO PCT/EP1996/005123 patent/WO1997019104A1/en not_active Application Discontinuation
- 1996-11-20 CZ CZ981549A patent/CZ154998A3/cs unknown
- 1996-11-20 DE DE69628323T patent/DE69628323T2/de not_active Expired - Lifetime
- 1996-11-20 AT AT96939867T patent/ATE240972T1/de not_active IP Right Cessation
- 1996-11-20 JP JP51765297A patent/JP3463691B2/ja not_active Expired - Fee Related
- 1996-11-20 TW TW085114246A patent/TW450978B/zh not_active IP Right Cessation
- 1996-11-20 AU AU76946/96A patent/AU712900B2/en not_active Ceased
- 1996-11-20 CO CO96061149A patent/CO4770985A1/es unknown
- 1996-11-20 IL IL12431096A patent/IL124310A0/xx unknown
- 1996-11-20 KR KR1019980703806A patent/KR19990071533A/ko not_active Application Discontinuation
- 1996-11-20 NZ NZ322909A patent/NZ322909A/xx unknown
- 1996-11-20 ES ES96939867T patent/ES2200079T3/es not_active Expired - Lifetime
- 1996-11-20 EP EP96939867A patent/EP0866801B1/de not_active Expired - Lifetime
- 1996-11-20 RU RU98111936/04A patent/RU2171260C2/ru not_active IP Right Cessation
- 1996-11-20 TR TR1998/00897T patent/TR199800897T2/xx unknown
1998
- 1998-05-19 NO NO982280A patent/NO982280D0/no not_active Application Discontinuation
- 1998-05-21 MX MX9804048A patent/MX9804048A/es unknown

Also Published As

Publication number	Publication date
NO982280L (no)	1998-05-19
KR19990071533A (ko)	1999-09-27
CA2237157C (en)	2009-04-07
AU712900B2 (en)	1999-11-18
CN1125079C (zh)	2003-10-22
NO982280D0 (no)	1998-05-19
US6011136A (en)	2000-01-04
HUP9903810A2 (hu)	2000-04-28
IL124310A0 (en)	1998-12-06
JP3463691B2 (ja)	2003-11-05
TR199800897T2 (xx)	1998-08-21
PL186010B1 (pl)	2003-09-30
CZ154998A3 (cs)	1998-08-12
EP0866801A1 (de)	1998-09-30
PE22998A1 (es)	1998-05-12
HUP9903810A3 (en)	2001-04-28
AU7694696A (en)	1997-06-11
TW450978B (en)	2001-08-21
NZ322909A (en)	1999-07-29
MX9804048A (es)	1998-09-30
CO4770985A1 (es)	1999-04-30
WO1997019104A1 (en)	1997-05-29
MY115877A (en)	2003-09-30
SK65698A3 (en)	1998-11-04
AR012286A1 (es)	2000-10-18
BR9611619A (pt)	1999-03-30
DE69628323D1 (en)	2003-06-26
PL326755A1 (en)	1998-10-26
DE69628323T2 (de)	2004-08-19
RU2171260C2 (ru)	2001-07-27
CA2237157A1 (en)	1997-05-29
ES2200079T3 (es)	2004-03-01
ATE240972T1 (de)	2003-06-15
CN1202904A (zh)	1998-12-23
JP2000502992A (ja)	2000-03-14
EP0866801B1 (de)	2003-05-21

Publication	Publication Date	Title
DE122005000024I1 (de)	2005-08-04	Darifenacin enthaltende Pharmazeutische Zubereitungen.
BR9607851B1 (pt)	2009-01-13	combinaÇço e formulaÇço farmacÊutica.
PT835246E (pt)	2002-04-29	Compostos aromaticos e composicoes farmaceuticas que os contem
BR9607317A (pt)	1997-12-30	Peptídios e composição farmacêutica
BR9607318A (pt)	1997-12-30	Peptidos e composição farmacêutica
NO962606L (no)	1996-12-23	Farmasöytisk sammensetning
PT876362E (pt)	2004-02-27	Novos taxoides sua preparacao e composicoes farmaceuticas que os contem
BR9710366A (pt)	1999-08-17	Derivados de taxane e drogas que os contêm
DE69618587D1 (de)	2002-02-21	Chinazoline und pharmazeutische zusammensetzungen
DZ2086A1 (fr)	2002-07-22	Benzylaminopipéridines substituées et compositionspharmaceutiques les contenant.
FI944832A0 (fi)	1994-10-14	Farmaseuttinen koostumus
MA26553A1 (fr)	2004-12-20	Alpha-aryl-n-alkylnitrones et compositions pharmaceutiques contenant ceux-la
NO981008D0 (no)	1998-03-06	Farmasöytisk formulering
MX9201710A (es)	1993-01-01	Carbamatos de rapamicina y composicion farmaceutica que los contiene.
BR9610530A (pt)	1999-07-06	Derivados de acriloilguanidina substituíduo com heteroarila e composiç es farmacêuticas contendo os mesmos
ITMI932540A0 (it)	1993-12-03	Composizione farmaceutica
BR9509688A (pt)	1997-09-30	Composto e composição farmacêutica
FI973229A0 (fi)	1997-08-05	Uusi farmaseuttinen koostumus
LV11727A (lv)	1997-04-20	Farmaceitiska kompozicija
FI973280A0 (fi)	1997-08-08	Farmaseuttinen koostumus
FI973230A0 (fi)	1997-08-05	Uusi farmaseuttinen formulaatio
BR9611619B1 (pt)	2010-08-10	ciclopeptolìdeos e composição farmacêutica que os contêm.
BR9606066A (pt)	1998-09-01	Composto e formulação farmacêutica
BR9605777A (pt)	1998-08-25	Composição farmacêutica
NO964309D0 (no)	1996-10-10	Farmasöytisk sammensetning

Legal Events

Date	Code	Title	Description
2006-11-28	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2007-08-14	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2008-10-21	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2009-10-20	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2010-08-10	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 10/08/2010, OBSERVADAS AS CONDICOES LEGAIS.
2013-10-08	B22O	Other matters related to patents and certificates of addition of invention: legal action concerning patent	Free format text: INPI-52400.062008/2013 ORIGEM: JUIZO DA 013A VARA FEDERAL DO RIO DE JANEIRO PROCESSO NO 0132270-62.2013.4.02.5101 ACAO DE NULIDADE DAS PATENTES SUBMETIDAS AO MAILBOX (ART. 229, PARAGRAFO UNICO DA LPI); ALTERNATIVAMENTE, A DECRETACAO DA NULIDADE PARCIAL PARA CORRECAO DO PRAZO DE VIGENCIA; SUBSIDIARIAMENTE, CASO SE ENTENDA NAO SER O CASO DE NULIDADE, A CORRECAO DO ATO ADMINISTRATIVO PARA ADEQUACAO DA VIGENCIA DAS PATENTES. AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL - INPI REU:NIPPON KAYAKU KABUSHIKI KAISHA, NOVARTIS AG, NOVARTIS SA, NOVARTISINS, NOVARTIS CONSUMER HEALTH S.A.
2013-10-29	B24H	Lapse because of non-payment of annual fees (definitively: art 78 iv lpi)	Free format text: EXTINCAO DEFINITIVA - ART. 78 INCISO IV DA LPI
2014-04-08	B19A	Notification of judicial decision: notification of judicial decision	Free format text: INPI-52400.104054/14 SECAO JUDICIARIA DO RIO DE JANEIRO-13A VARA FEDERAL DO RIO DE JANEIRO PROCESSO NO0001852-02.2014.4.02.5101 AUTOR:INPI-INSTITUTO NACIONAL DE PROPRIEDADE INDUSTRIAL REU(S):NOVARTIS AG (NOVARTIS AS)(NOVARTIS INC.) E NOVARTIS CONSUMER HEALTH S.A DECISAO:HOMOLOGO O ACORDO FIRMADO,JULGAMENTO EXTINTO O PROCESSO COM RESOLUCAO DE MERITO, FORTE NO ART.269,III DO CODIGO DE PROCESSO CIVIL.
2020-11-24	B24F	Patent annual fee: publication cancelled	Free format text: ANULADA A PUBLICACAO CODIGO 24.8 NA RPI NO 2234 DE 29/10/2013 POR TER SIDO INDEVIDA.
2021-09-14	B21F	Lapse acc. art. 78, item iv - on non-payment of the annual fees in time	Free format text: REFERENTE A 15O, 16O, 17O, 18O, 19O E 20O RETRIBUICAO ANUAL.