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BR9609812B8 - Para-herquamidas e marcfortinas antiparasíticas. - Google Patents

Para-herquamidas e marcfortinas antiparasíticas.

Info

Publication number
BR9609812B8
BR9609812B8 BRPI9609812-0B8A BR9609812A BR9609812B8 BR 9609812 B8 BR9609812 B8 BR 9609812B8 BR 9609812 A BR9609812 A BR 9609812A BR 9609812 B8 BR9609812 B8 BR 9609812B8
Authority
BR
Brazil
Prior art keywords
marcfortines
antiparasitic
parameters
antiparasitic parameters
Prior art date
Application number
BRPI9609812-0B8A
Other languages
English (en)
Other versions
BR9609812A (pt
Inventor
Byung H Lee
Michael F Clothier
Original Assignee
Zoetis P & U Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21695455&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9609812(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zoetis P & U Llc filed Critical Zoetis P & U Llc
Publication of BR9609812A publication Critical patent/BR9609812A/pt
Publication of BR9609812B8 publication Critical patent/BR9609812B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pest Control & Pesticides (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Percussion Or Vibration Massage (AREA)
  • Epoxy Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
BRPI9609812-0B8A 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas. BR9609812B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US132495P 1995-07-21 1995-07-21
PCT/US1996/010686 WO1997003988A1 (en) 1995-07-21 1996-06-26 Antiparasitic marcfortines and paraherquamides

Publications (2)

Publication Number Publication Date
BR9609812A BR9609812A (pt) 1999-03-02
BR9609812B8 true BR9609812B8 (pt) 2014-10-29

Family

ID=21695455

Family Applications (7)

Application Number Title Priority Date Filing Date
BRPI9612972-7B8A BR9612972B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612944-1B8A BR9612944B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas antiparasíticas.
BRPI9612963-8B8A BR9612963B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612974-3B8A BR9612974B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612973-5B8A BR9612973B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612975-1B8A BR9612975B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9609812-0B8A BR9609812B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.

Family Applications Before (6)

Application Number Title Priority Date Filing Date
BRPI9612972-7B8A BR9612972B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612944-1B8A BR9612944B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas antiparasíticas.
BRPI9612963-8B8A BR9612963B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612974-3B8A BR9612974B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612973-5B8A BR9612973B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.
BRPI9612975-1B8A BR9612975B8 (pt) 1995-07-21 1996-06-26 Para-herquamidas e marcfortinas antiparasíticas.

Country Status (31)

Country Link
US (2) US5703078A (pt)
EP (3) EP0871631B1 (pt)
JP (2) JP4122447B2 (pt)
KR (1) KR100428335B1 (pt)
CN (2) CN1277830C (pt)
AR (10) AR003466A1 (pt)
AT (1) ATE311390T1 (pt)
AU (1) AU699644B2 (pt)
BR (7) BR9612972B8 (pt)
CA (1) CA2225813C (pt)
CO (1) CO4750664A1 (pt)
CZ (1) CZ296008B6 (pt)
DE (1) DE69635524T2 (pt)
DK (2) DK1489082T3 (pt)
ES (2) ES2439569T3 (pt)
FI (2) FI115912B (pt)
HK (2) HK1017883A1 (pt)
HU (1) HU226296B1 (pt)
ID (1) ID30373A (pt)
MX (1) MX9800625A (pt)
MY (1) MY113806A (pt)
NO (1) NO324287B1 (pt)
NZ (1) NZ311952A (pt)
PL (1) PL185007B1 (pt)
PT (1) PT1489082E (pt)
RU (1) RU2162090C2 (pt)
SI (1) SI0871631T1 (pt)
SK (2) SK284833B6 (pt)
TW (1) TW334436B (pt)
WO (1) WO1997003988A1 (pt)
ZA (1) ZA965908B (pt)

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ZA976761B (en) * 1996-09-09 1999-01-29 Upjohn Co 25 Methylene and 24,25-epoxy marcfortines and paraherquamides
AU4911097A (en) * 1996-11-15 1998-06-03 Pharmacia & Upjohn Company 1- and 2-substituted marcfortines and paraherquamides as antiparasitic agents
PE20011289A1 (es) * 2000-04-07 2001-12-21 Upjohn Co Composiciones antihelminticas que comprenden lactonas macrociclicas y espirodioxepinoindoles
CA2945453C (en) 2008-11-14 2021-03-02 Merial, Inc. Enantiomerically enriched aryloazol-2-yl cyanoethylamino paraciticidal compounds
WO2010059529A2 (en) 2008-11-19 2010-05-27 Merial Limited Compositions comprising an aryl pyrazole and/or a formamidine, methods and uses thereof
US8426460B2 (en) 2008-12-04 2013-04-23 Merial Limited Dimeric avermectin and milbemycin derivatives
EP2314292A1 (en) 2009-10-20 2011-04-27 Novartis AG Endoparasiticidal compositions
US8846569B2 (en) 2009-12-04 2014-09-30 Merial Limited Pesticidal bis-organosulfur compounds
TR201907244T4 (tr) 2009-12-17 2019-06-21 Boehringer Ingelheim Animal Health Usa Inc Anti̇parazi̇ti̇k di̇hi̇droazol bi̇leşi̇mleri̇
AU2010330844B2 (en) 2009-12-17 2014-11-27 Boehringer Ingelheim Animal Health USA Inc. Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
CA2818563C (en) 2010-11-16 2019-11-12 Merial Limited Monensin derivatives for the treatment and prevention of protozoal infections.
MX344911B (es) 2011-06-27 2017-01-11 Merial Inc Compuestos de eter amido-piridilico y composiciones y su uso contra parasitos.
US20120329832A1 (en) 2011-06-27 2012-12-27 Jean Delaveau Novel Insect-Repellent Coumarin Derivatives, Syntheses, and Methods of Use
EA026947B1 (ru) 2011-09-12 2017-06-30 Мериал, Инк. Пестицидные композиции, содержащие изоксазолиновый активный ингредиент, и способы их применения
US20130079394A1 (en) 2011-09-23 2013-03-28 Cnrs (Centre National Recherche Scientifique) Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
BR112014011775A8 (pt) 2011-11-17 2017-07-11 Merial Ltd Composições compreendendo um aril pirazol e um imidazol substituído, métodos e usos dos mesmos
PT3351546T (pt) 2011-12-02 2024-03-07 Boehringer Ingelheim Vetmedica Gmbh Formulações injectáveis de moxidectina com ação prolongada
EA030398B1 (ru) 2012-02-06 2018-07-31 Мериал, Инк. Паразитицидные пероральные ветеринарные композиции, включающие системно действующие активные агенты, способы и применение этих композиций и способов
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
EP2895465B1 (en) 2012-04-20 2018-10-03 Merial, Inc. Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof
JP5737255B2 (ja) * 2012-09-27 2015-06-17 ダイキン工業株式会社 チオノカルボン酸エステルの製造方法
ES2893777T3 (es) 2012-11-20 2022-02-10 Boehringer Ingelheim Animal Health Usa Inc Compuestos y composiciones antihelmínticas y procedimiento de utilización de los mismos
US9447084B2 (en) 2013-11-01 2016-09-20 Merial, Inc. Antiparisitic and pesticidal isoxazoline compounds
AU2015247463B2 (en) 2014-04-17 2018-03-29 Basf, Se Use of malononitrile compounds for protecting animals from parasites
ES2842592T3 (es) 2014-05-19 2021-07-14 Boehringer Ingelheim Animal Health Usa Inc Compuestos antihelmínticos
BR122020023385B1 (pt) 2014-06-19 2021-05-25 Merial, Inc composições parasiticidas compreendendo derivados de indol, métodos e usos dos mesmos
US10864193B2 (en) 2014-10-31 2020-12-15 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising fipronil at high concentrations
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
WO2016187534A1 (en) 2015-05-20 2016-11-24 Merial, Inc. Anthelmintic depsipeptide compounds
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
CN110381738B (zh) 2016-10-14 2021-07-16 勃林格殷格翰动物保健美国公司 农药的和杀寄生物的乙烯基异噁唑啉化合物
WO2018093920A1 (en) 2016-11-16 2018-05-24 Merial, Inc. Anthelmintic depsipeptide compounds
BR112020003217A2 (pt) 2017-08-14 2020-10-06 Boehringer Ingelheim Animal Health USA Inc. compostos pesticidas e parasiticidas de pirazolisoxazolina
EP3749096A1 (en) 2018-02-08 2020-12-16 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
US20220048903A1 (en) 2018-07-09 2022-02-17 Boehringer Ingelheim Animal Health USA Inc. Anthelminthic Heterocyclic Compounds
WO2020112374A1 (en) 2018-11-20 2020-06-04 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
AR118215A1 (es) 2019-03-01 2021-09-22 Boehringer Ingelheim Animal Health Usa Inc Composiciones inyectables de clorsulón, sus métodos y usos
PE20220281A1 (es) 2019-03-19 2022-02-25 Boehringer Ingelheim Animal Health Usa Inc Compuestos de aza-benzotiofeno y aza-benzofurano como antihelminticos
KR20230028268A (ko) 2020-05-29 2023-02-28 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 구충성 헤테로시클릭 화합물
CN111748503B (zh) * 2020-08-04 2021-12-14 华中农业大学 一种深海独岛枝芽胞杆菌培养基和剂型
AU2021410052A1 (en) 2020-12-21 2023-08-03 Boehringer Ingelheim Vetmedica Gmbh Parasiticidal collar comprising isoxazoline compounds
WO2023156938A1 (en) 2022-02-17 2023-08-24 Boehringer Ingelheim Vetmedica Gmbh Method and system for providing a fluid product mailer

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US5075307A (en) * 1987-07-28 1991-12-24 Merck & Co., Inc. Paraherquamide and dihydroparaherquamide as antihelminthic agents
US4873247A (en) * 1987-11-27 1989-10-10 Goegelman Robert T Derivatives of paraherquamide isolated from a fermentation broth active as antiparasitic agents
US4978656A (en) * 1988-08-12 1990-12-18 Merck & Co., Inc. Synthetic derivatives of paraherquamide
US4866060A (en) * 1988-08-19 1989-09-12 Merck & Co., Inc. Use of the natural product marcfortines as antiparasitic agents
US4923867A (en) * 1988-08-24 1990-05-08 Merck & Co., Inc. Synthetic marcfortine derivatives useful as antiparasitic agents
NZ233043A (en) * 1989-03-30 1992-09-25 Merck & Co Inc Anthelmintic heterocyclic compounds prepared by action of cunninghamella blakesleeana on (dihydro)paraherquamide
IE904606A1 (en) * 1989-12-21 1991-07-03 Beecham Group Plc Novel products
GB9014194D0 (en) * 1990-06-26 1990-08-15 Pfizer Ltd Antiparasitic agents
WO1992022555A1 (en) * 1991-06-17 1992-12-23 Beecham Group Plc Paraherquamide derivatives, precursor thereof, processes for their preparation, microorganism used and their use as antiparasitic agents
TW410227B (en) * 1993-06-16 2000-11-01 Upjohn Co 14-substituted marcfortines and derivatives useful as antiparasitic agents

Also Published As

Publication number Publication date
DK0871631T3 (da) 2006-03-13
FI980112A (fi) 1998-01-20
PT1489082E (pt) 2013-12-23
NO980255D0 (no) 1998-01-20
BR9612944B8 (pt) 2014-10-29
HK1017883A1 (en) 1999-12-03
US5703078A (en) 1997-12-30
AR038434A2 (es) 2005-01-12
EP1400523A2 (en) 2004-03-24
PL324574A1 (en) 1998-06-08
AU699644B2 (en) 1998-12-10
BR9612963B8 (pt) 2014-10-29
BR9612975B8 (pt) 2014-10-29
BR9609812A (pt) 1999-03-02
JPH11509550A (ja) 1999-08-24
FI118471B (fi) 2007-11-30
NZ311952A (en) 1999-03-29
DE69635524T2 (de) 2006-07-06
FI115912B (fi) 2005-08-15
CA2225813C (en) 2008-02-26
RU2162090C2 (ru) 2001-01-20
HUP9802221A3 (en) 2000-05-29
ZA965908B (en) 1997-01-12
ID30373A (id) 1997-01-23
SI0871631T1 (sl) 2006-04-30
CA2225813A1 (en) 1997-02-06
EP1489082A1 (en) 2004-12-22
NO324287B1 (no) 2007-09-17
AR038428A2 (es) 2005-01-12
BR9612974B8 (pt) 2014-10-29
AR038433A2 (es) 2005-01-12
EP1400523A3 (en) 2004-04-07
WO1997003988A1 (en) 1997-02-06
ES2439569T3 (es) 2014-01-23
US5750695A (en) 1998-05-12
AR038430A2 (es) 2005-01-12
FI20050238A (fi) 2005-03-04
CZ11098A3 (cs) 1998-06-17
FI980112A0 (fi) 1998-01-20
AU6337396A (en) 1997-02-18
SK5498A3 (en) 1998-08-05
AR038427A2 (es) 2005-01-12
DE69635524D1 (de) 2006-01-05
EP0871631A1 (en) 1998-10-21
TW334436B (en) 1998-06-21
CN1191537A (zh) 1998-08-26
JP4122447B2 (ja) 2008-07-23
CZ296008B6 (cs) 2005-12-14
AR038429A2 (es) 2005-01-12
PL185007B1 (pl) 2003-01-31
BR9612972B8 (pt) 2014-10-29
SK285248B6 (sk) 2006-09-07
KR100428335B1 (ko) 2004-06-16
HU226296B1 (hu) 2008-08-28
JP2008007516A (ja) 2008-01-17
MX9800625A (es) 1998-04-30
HK1061242A1 (en) 2004-09-10
EP1489082B1 (en) 2013-11-20
AR052907A1 (es) 2007-04-11
CN1125824C (zh) 2003-10-29
BR9612973B8 (pt) 2014-10-29
CN1277830C (zh) 2006-10-04
AR038432A2 (es) 2005-01-12
EP0871631B1 (en) 2005-11-30
SK284833B6 (sk) 2005-12-01
DK1489082T3 (da) 2013-12-09
AR038431A2 (es) 2005-01-12
CN1495183A (zh) 2004-05-12
AR003466A1 (es) 1998-08-05
MY113806A (en) 2002-05-31
ES2249783T3 (es) 2006-04-01
HUP9802221A2 (hu) 1999-02-01
CO4750664A1 (es) 1999-03-31
ATE311390T1 (de) 2005-12-15
NO980255L (no) 1998-03-20

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 15/01/2008, OBSERVADAS AS CONDICOES LEGAIS.

B22O Other matters related to patents and certificates of addition of invention: legal action concerning patent

Free format text: INPI-50400.061581/2013 ORIGEM: JUIZO DA 013A VARA FEDERAL DO RIO DE JANEIRO PROCESSO NO 0132366-77.2013.4.02.5101 ACAO DE NULIDADE DAS PATENTES SUBMETIDAS AO MAILBOX (ART. 229, PARAGRAFO UNICO DA LPI); ALTERNATIVAMENTE, A DECRETACAO DA NULIDADE PARCIAL PARA CORRECAO DO PRAZO DE VIGENCIA; SUBSIDIARIAMENTE, CASO SE ENTENDA NAO SER O CASO DE NULIDADE, A CORRECAO DO ATO ADMINISTRATIVO PARA ADEQUACAO DA VIGENCIA DAS PATENTES. AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL - INPI REU: PHARMACIA AND UPJOHN COMPANY, PASTEUR MERIEUX SERUMS ET VACCINS S.A.NOVEN PHARMACEUTICALS, INC.

B25D Requested change of name of applicant approved

Owner name: PHARMACIA AND UPJOHN COMPANY LLC (US)

B25A Requested transfer of rights approved

Owner name: PAH PANDU LLC (US)

B25D Requested change of name of applicant approved

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