[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

BR9301627A - Processo para preparar cefalosporinas - Google Patents

Processo para preparar cefalosporinas

Info

Publication number
BR9301627A
BR9301627A BR9301627A BR9301627A BR9301627A BR 9301627 A BR9301627 A BR 9301627A BR 9301627 A BR9301627 A BR 9301627A BR 9301627 A BR9301627 A BR 9301627A BR 9301627 A BR9301627 A BR 9301627A
Authority
BR
Brazil
Prior art keywords
amino
cephalosporanic
alpha
derivatives
acid
Prior art date
Application number
BR9301627A
Other languages
English (en)
Inventor
John Paul Gardner
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BR9301627A publication Critical patent/BR9301627A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/04—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by acylation of the substituent in the 7 position
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/01—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amides (3.5.1)
    • C12Y305/01011—Penicillin amidase (3.5.1.11), i.e. penicillin-amidohydrolase

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Cephalosporin Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Enzymes And Modification Thereof (AREA)
BR9301627A 1992-04-24 1993-04-22 Processo para preparar cefalosporinas BR9301627A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87425792A 1992-04-24 1992-04-24

Publications (1)

Publication Number Publication Date
BR9301627A true BR9301627A (pt) 1993-10-26

Family

ID=25363336

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9301627A BR9301627A (pt) 1992-04-24 1993-04-22 Processo para preparar cefalosporinas

Country Status (22)

Country Link
US (1) US5801011A (pt)
EP (1) EP0567323B1 (pt)
JP (1) JPH069649A (pt)
KR (1) KR930021643A (pt)
CN (1) CN1063491C (pt)
AT (1) ATE183778T1 (pt)
AU (1) AU664078B2 (pt)
BR (1) BR9301627A (pt)
CA (1) CA2094686A1 (pt)
CZ (1) CZ69593A3 (pt)
DE (1) DE69326095T2 (pt)
DK (1) DK0567323T3 (pt)
ES (1) ES2135446T3 (pt)
FI (1) FI931815A (pt)
GR (1) GR3031739T3 (pt)
HU (1) HUT64352A (pt)
IL (1) IL105494A (pt)
MX (1) MX9302354A (pt)
NO (1) NO931483L (pt)
NZ (1) NZ247464A (pt)
YU (1) YU27893A (pt)
ZA (1) ZA932809B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998056945A1 (en) * 1997-06-10 1998-12-17 Dsm N.V. PROCESS FOR ENZYMATICALLY PREPARING A β-LACTAM ANTIBIOTIC AND THIS ANTIBIOTIC
CZ200782A3 (cs) 2007-01-31 2009-05-27 Mikrobiologický ústav AV CR, v.v.i. Sekvence nukleotidu o velikosti 2646 bp, kódující penicilinacylázu, nové konstrukty rekombinantní nukleové kyseliny a rekombinantní mikroorganismy nesoucí tuto sekvenci
CN101429538B (zh) * 2008-12-12 2011-05-25 河北九派制药有限公司 7-α-甲氧基-3-去乙酰基头孢噻吩苄星盐的制备方法
CN103805671B (zh) * 2013-11-11 2015-08-26 华北制药河北华民药业有限责任公司 一种制备头孢氨苄的方法
CN105002253B (zh) * 2015-07-09 2019-02-15 山东罗欣药业集团恒欣药业有限公司 一种新型头孢类抗感染药物的酶促合成工艺
US20170101660A1 (en) * 2015-10-07 2017-04-13 Gwangju Institute Of Science And Technology Enzyme-immobilized porous membrane and preparation method of antibiotics using the same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5548797B1 (pt) * 1971-04-02 1980-12-08
IL39158A (en) * 1971-04-28 1977-08-31 Snam Progetti Enzymatic scission and synthesis of penicillins and cephalosporins
IT1045797B (it) * 1973-12-20 1980-06-10 Snam Progetti Procedimento per la sintesi enzimatica di penicilline e cefalosporine semisintetiche mediante una acilasi insolubile
US4113566A (en) * 1976-11-26 1978-09-12 Pfizer Inc. Process for preparing 6-aminopenicillanic acid
CH640240A5 (en) * 1979-02-09 1983-12-30 I B S A Inst Biochimique Sa Preparation of penicillins and cephalosporins from precursors obtained by hydrolysis of natural penicillins/cephalosporins, using enzymatic complexes immobilised on solid carriers
JPH0791291B2 (ja) * 1985-12-30 1995-10-04 イ−ライ・リリ−・アンド・カンパニ− １−カルバセフアロスポリン抗生物質
RU2136759C1 (ru) * 1990-07-04 1999-09-10 Гист-Брокадс Б.В. Способ получения производного бета-лактама
IT1243800B (it) * 1990-08-28 1994-06-28 Sclavo Spa Procedimento migliorato per la preparazione di cefalosporine
JPH07502168A (ja) * 1991-12-19 1995-03-09 ジスト―ブロカデス　ベスローテン　フェンノートシャップ 或る種のβ−ラクタム抗生物質の改善された製造方法
GB9204439D0 (en) * 1992-02-27 1992-04-15 Fujisawa Pharmaceutical Co A new cephalosporin c acylase

Also Published As

Publication number Publication date
FI931815A0 (fi) 1993-04-22
ATE183778T1 (de) 1999-09-15
YU27893A (sh) 1996-07-24
AU3712593A (en) 1993-10-28
NZ247464A (en) 1994-12-22
CN1063491C (zh) 2001-03-21
HUT64352A (en) 1993-12-28
US5801011A (en) 1998-09-01
CA2094686A1 (en) 1993-10-25
IL105494A0 (en) 1993-08-18
NO931483D0 (no) 1993-04-22
CZ69593A3 (en) 1993-12-15
FI931815A (fi) 1993-10-25
KR930021643A (ko) 1993-11-22
GR3031739T3 (en) 2000-02-29
HU9301188D0 (en) 1993-07-28
DE69326095D1 (de) 1999-09-30
MX9302354A (es) 1994-05-31
JPH069649A (ja) 1994-01-18
EP0567323A3 (pt) 1994-04-27
EP0567323A2 (en) 1993-10-27
ZA932809B (en) 1994-10-21
CN1077749A (zh) 1993-10-27
DE69326095T2 (de) 2000-01-20
IL105494A (en) 2000-08-13
AU664078B2 (en) 1995-11-02
EP0567323B1 (en) 1999-08-25
DK0567323T3 (da) 1999-12-13
ES2135446T3 (es) 1999-11-01
NO931483L (no) 1993-10-25

Similar Documents

Publication Publication Date Title
DE69119216D1 (de) Enzymatisches Verfahren zur Herstellung von 7-Aminocephalosporinsäure und Derivate
BR9301627A (pt) Processo para preparar cefalosporinas
DE3066574D1 (en) Optically pure heterocyclic amino acids, process for their preparation and their use
EP0582102B1 (en) A method for the acylation of the 7-amino group of the cephalosporanic ring
AU8304587A (en) Method for preparing crystalline cefadroxil monohydrate
AU548727B2 (en) Beta-lactam acetic acid derivatives
DE3563858D1 (en) Process for the preparation of l-alpha-aminoacids
ES484380A1 (es) Un procedimiento no catalitico para la preparacion de deri- vados de cefalosporina
RU93004674A (ru) Способ получения цефалоспоринов
IL81555A0 (en) Enzymatic process for 3-substituted cephalosporins
IE921073A1 (en) Enzymatic process for the production of cefonicid
TH13553A (th) กรรมวิธีที่ดีขึ้นสำหรับเตรียมเซฟาโลสพอรินส์
ES2002912A6 (es) Procedimiento para la produccion de antibioticos de cefalosporina
YU44104B (en) Process for obtaining 7-amino-cephalosporanic acid derivatives
ATE41417T1 (de) Verfahren zur herstellung von 4-halogen-2hydroxyimino-acetessigsaeureestern.
JPH05184377A (ja) ３−ヒドロキシメチルセファロスポラン酸誘導体の製造方法
JPH0649075A (ja) ３−ヒドロキシメチルセファロスポラン酸誘導体の製法
DE69016714D1 (de) Verfahren zur Herstellung 2-Methoxyimino-2- (5-amino-1,2,4-thiadiazol-3-yl)essigsäure oder ihrer Salze.
BG51517A1 (en) Cephem derivatives of 5-carboxy-2-benzoxazolon and a method for their production
KR930012788A (ko) 7-adca 유도체의 제조방법
FI863678A (fi) Foerfarande foer submers odling av pseudomonas aeruginosa-bakteriestammar.

Legal Events

Date Code Title Description
EE Request for examination
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal