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BR112022002390A2 - Inibidores de jak - Google Patents

Inibidores de jak

Info

Publication number
BR112022002390A2
BR112022002390A2 BR112022002390A BR112022002390A BR112022002390A2 BR 112022002390 A2 BR112022002390 A2 BR 112022002390A2 BR 112022002390 A BR112022002390 A BR 112022002390A BR 112022002390 A BR112022002390 A BR 112022002390A BR 112022002390 A2 BR112022002390 A2 BR 112022002390A2
Authority
BR
Brazil
Prior art keywords
jak inhibitors
jak
inhibitors
disorders
diseases
Prior art date
Application number
BR112022002390A
Other languages
English (en)
Inventor
Jason Harris
John Nuss
Raju Mohan
Shendong Yuan
Original Assignee
Vimalan Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vimalan Biosciences Inc filed Critical Vimalan Biosciences Inc
Publication of BR112022002390A2 publication Critical patent/BR112022002390A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

são descritos nesse documento inibidores de janus quinase (jak) e métodos de utilização de inibidores de jak no tratamento de doenças, distúrbios ou condições. também são descritas nesse documento composições farmacêuticas contendo tais compostos.
BR112022002390A 2019-08-08 2020-08-07 Inibidores de jak BR112022002390A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962884593P 2019-08-08 2019-08-08
PCT/US2020/045431 WO2021026465A1 (en) 2019-08-08 2020-08-07 Jak inhibitors

Publications (1)

Publication Number Publication Date
BR112022002390A2 true BR112022002390A2 (pt) 2022-06-14

Family

ID=74499223

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112022002390A BR112022002390A2 (pt) 2019-08-08 2020-08-07 Inibidores de jak

Country Status (13)

Country Link
US (2) US11459333B2 (pt)
EP (1) EP4009967A4 (pt)
JP (1) JP2022544174A (pt)
KR (1) KR20220051351A (pt)
CN (1) CN115038436A (pt)
AR (1) AR119625A1 (pt)
AU (1) AU2020325152A1 (pt)
BR (1) BR112022002390A2 (pt)
CA (1) CA3150281A1 (pt)
IL (1) IL290381A (pt)
MX (1) MX2022001702A (pt)
TW (1) TW202122400A (pt)
WO (1) WO2021026465A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2021013602A (es) 2019-05-08 2022-04-06 Vimalan Biosciences Inc Inhibidores de jak.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009513571A (ja) 2005-09-30 2009-04-02 バーテックス ファーマシューティカルズ インコーポレイテッド ヤヌスキナーゼ阻害剤として有用なデアザプリン
JO3235B1 (ar) * 2006-05-26 2018-03-08 Astex Therapeutics Ltd مركبات بيررولوبيريميدين و استعمالاتها
EP2108020A2 (en) 2007-01-30 2009-10-14 Biogen Idec MA, Inc. 1-h-pyrazolo[3,4b]pyrimidine derivatives and their use as modulators of mitotic kinases
PE20091485A1 (es) * 2008-02-06 2009-10-26 Novartis Ag DERIVADOS DE PIRROLO-[2,3-d]-PIRIMIDINA COMO INHIBIDORES DE CINASAS
JP5744887B2 (ja) 2009-10-20 2015-07-08 セルゾーム リミティッド Ｊａｋ阻害剤としてのヘテロシクリルピラゾロピリミジン類似体
KR20130094693A (ko) * 2010-04-30 2013-08-26 셀좀 리미티드 Ｊａｋ 저해제로서의 피라졸 화합물
WO2012143320A1 (en) 2011-04-18 2012-10-26 Cellzome Limited (7h-pyrrolo[2,3-d]pyrimidin-2-yl)amine compounds as jak3 inhibitors
KR20150027267A (ko) 2012-06-29 2015-03-11 화이자 인코포레이티드 LRRK2 억제제로서의 4-(치환된-아미노)-7H-피롤로[2,3-d]피리미딘
WO2016208595A1 (ja) 2015-06-22 2016-12-29 小野薬品工業株式会社 Ｂｒｋ阻害化合物
MX2021013602A (es) 2019-05-08 2022-04-06 Vimalan Biosciences Inc Inhibidores de jak.

Also Published As

Publication number Publication date
JP2022544174A (ja) 2022-10-17
US11459333B2 (en) 2022-10-04
CA3150281A1 (en) 2021-02-11
US20210040100A1 (en) 2021-02-11
IL290381A (en) 2022-04-01
AR119625A1 (es) 2021-12-29
KR20220051351A (ko) 2022-04-26
AU2020325152A1 (en) 2022-03-10
TW202122400A (zh) 2021-06-16
EP4009967A4 (en) 2023-07-26
EP4009967A1 (en) 2022-06-15
US20230312589A1 (en) 2023-10-05
MX2022001702A (es) 2022-04-20
WO2021026465A1 (en) 2021-02-11
CN115038436A (zh) 2022-09-09

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