BR112020025309A2 - STABLE COMPOSITION OF WIDE SPECTRUM, MIXTURE, METHOD FOR INCREASING PLANT DEVELOPMENT, METHOD FOR CONTROLLING NEMATOIDS, METHOD FOR REGULATING PLANT GROWTH AND METHOD FOR PREPARING STABLE COMPOSITION OF WIDE SPECTRUM - Google Patents

Abstract

"broad spectrum stable composition, mixture, method for increasing plant growth, method for controlling nematodes, method for regulating plant growth and method for preparing the stable broad spectrum composition" The present invention provides compositions and mixtures comprising fluensulfone, fipronil and azoxystrobin and uses thereof.

Description

“STABLE COMPOSITION OF WIDE SPECTRUM, MIXTURE, METHOD FOR INCREASING PLANT DEVELOPMENT, METHOD FOR CONTROLLING NEMATOIDS, METHOD FOR REGULATING PLANT GROWTH AND METHOD FOR PREPARING STABLE COMPOSITION OF WIDE SPECTRUM”

[0001] Throughout this patent application, several publications are mentioned. The disclosures of these documents and publications referred to herein without incorporate in full by reference in this patent application. Field of the present invention

[0002] The present invention relates to compositions and mixtures comprising fluensulfone, fipronil and azoxystrobin, as well as the preparation and uses thereof. History of the present invention

[0003] The protection of culture is critical from the early stages of the development of culture. The prevention of pests and diseases at the root of the crop during root development increases the health and yield of the crop.

[0004] Younger roots are more sensitive and there is a need to develop multifunctional mixtures with a broad spectrum of activity against pests and diseases that affect the crop during the early stages of crop development.

[0005] The roots are highly affected by nematodes, insects and pathogens at the plant site.

[0006] Fluensulfone (5-chloro-2- (3,4,4-trifluor-3-buten-1-yl-sulfonyl) -1,3-thiazole) is a nematocide that has a significantly reduced environmental impact with low toxicity to non-target mammals and insects. The mode of action of fluensulfone is distinct from the nematicides currently available and, therefore, presents a promising new chemical entity for crop protection.

[0007] Insecticides and fungicides are also needed to improve root development.

[0008] Fipronil, ((RS) -5-amino-1- [2,6-dichloro-4- (trifluoromethyl) phenyl] -4- (trifluoromethylsulfinyl) -1H-pyrazol-3-carbonitrile ) and azoxystrobin, methyl (2E) -2- (2 - {[6- (2-cyano-phenoxy) pyrimidin-4-yl] oxy} phenyl) -3-methoxy-acrylate) are well-known pesticides that can be used to protect the root from plant pathogen pests and infections.

[0009] Based on the above, there is a need in the technique to find a simple and uniform solution to protect a culture in the critical phase of its growth, to improve the development of the root system and to promote a better and more efficient rooting in the culture.

[0010] There is a need in the art to develop a broad spectrum treatment that is effective to control attacks of multiple pests on plantations in a simple and effective way. Summary of the present invention

[0011] The present invention provides a stable composition comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0012] The present invention provides a stable composition for controlling nematodes, improving plant development, regulating plant growth, preventing plant and / or soil disease, and / or controlling plant and / or soil disease, the composition comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III)

an effective amount of azoxystrobin.

[0013] The present invention further provides a stable composition comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an aqueous carrier, and (V) an organic carrier, where azoxystrobin and fipronil are suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier.

[0014] The present invention provides a stable composition comprising The present invention further provides a stable composition comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an aqueous carrier, (V) an organic carrier and (VI) at least one physically stabilizing additive, with azoxystrobin and fipronil being suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier.

[0015] The present invention provides a stable composition comprising The present invention further provides a stable composition comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an aqueous carrier, (V) an organic carrier and (VI) a physically stabilizing system, with azoxystrobin and fipronil being suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier.

[0016] The present invention also provides for the use of polyvinylpyrrolidone to stabilize a composition comprising (I) an effective amount of fluensulfone, (II)

an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0017] The present invention also provides for the use of a combination of polyvinylpyrrolidone and poly (alkylene oxide) block copolymer to stabilize a composition comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and ( III) an effective amount of azoxystrobin.

[0018] The present invention provides a method for controlling nematodes, improving plant development, regulating plant growth, preventing plant and / or soil disease, and / or controlling plant and / or soil disease, the method being comprises applying an effective amount of any of the mixtures or compositions disclosed herein to the plant, plant location or plant propagation material in order to control nematodes, improve plant development, regulate plant growth, prevent plant disease and / or soil, and / or controlling plant and / or soil disease.

[0019] The present invention provides a method for controlling nematodes, improving plant development, regulating plant growth, preventing plant and / or soil disease, and / or controlling plant and / or soil disease, the method being comprises applying (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin to the plant, plant site or plant propagation material in order to control nematode, improve the development of regulate plant growth, prevent plant and / or soil disease, and / or control plant and / or soil disease.

[0020] The invention provides a process for preparing the stable composition described herein, the process comprising the steps of: (1) grinding a dispersion of fipronil and azoxystrobin in water in the presence of polyvinylpyrrolidone; (2) dissolving fluensulfone in a fatty acid N, N-dimethyl amide derivative to obtain a solution; (3) preparing an emulsion from the solution obtained in step (2); and (4) preparing the suspension composition from the dispersion obtained from step (1) and the emulsion from step (3). Detailed description of the invention Definitions

[0021] Before defining the present invention in detail, it may be useful to provide definitions of certain terms to be used here. Unless otherwise defined, all technical and scientific terms used herein have the same meaning as is commonly understood by a specialist in the technique to which the subject belongs.

[0022] When used here, the term "broad spectrum" is used to describe efficiency against a wide range of diseases and infections of the plant, its location or its propagating material.

[0023] When used here, the term "stable" when used in connection with physical stabilization or when used in connection with a composition means that no crystallization and / or significant thickening has been observed after at least 2 weeks of storage at a temperature of at least 50 ° C. The term "stable" when used in connection with suspoemulsion means that no crystallization and / or significant thickening was observed after at least 2 weeks of storage at a temperature of at least 50 ° C.

[0024] Stability is assessed according to the CIPAC test protocols. The physical stability of the composition is tested using CIPAC methodologies: MT test 36.3 - Emulsion (5%) 342 ppm of water (2h); Wet sieve test MT 185; MT

148.1 - Ability to flow; MT 39.3 - Stability of storage at 0 ° C; and MT 184 - Suspensibility.

[0025] The CIPAC test is standard in the relevant industry for assessing storage stability before and after. Stability can be assessed under normal storage conditions, after two years of storage at room temperature. Stability can also be assessed under accelerated storage conditions, after 2 weeks storage at 54 ° C or equivalent or after 8 weeks at 40 ° C or after 12 weeks at 35 ° C.

[0026] When used here, the term "effective" when used to describe a method for controlling an unwanted pest, such as nematodes, means that the method provides a good level of control of the unwanted pest without significantly interfering with normal growth and development of culture.

[0027] When used here, the term "effective amount" when used in connection with an active component refers to an amount of the active component that, when ingested, contacted with or felt, is sufficient to achieve a good level of control or activity.

[0028] When used herein, the term "effective amount" when used in connection with a non-active component, that is, an additive, for example, a polymer or organic carrier, refers to an amount of the additive that is sufficient to improve composition stability.

[0029] When used herein, the term "agriculturally acceptable carrier" means carriers that are known and accepted in the art for forming compositions for agricultural or horticultural use.

[0030] When used here, the term "adjuvant" is broadly defined as any substance that in itself is not an active ingredient, but that increases or is intended to increase the effectiveness of the pesticide with which it is used. Adjuvants can be understood as including, but not limited to, spreading agents, penetrants, compatibility agents and displacement retardants.

[0031] When used herein, the term "agriculturally acceptable inert additives" is defined with any substance which itself is not an active ingredient, but which is added to the composition such as thickening agent, adhesion agents, surfactants, antioxidant agent, agents defoamers and thickeners.

[0032] When used here, the term "tank mix" means that two or more chemical pesticides or compositions are mixed in the spray tank at the time of spray application.

[0033] When used here, the term "ready mix" means a composition that can be applied to plants directly after dilution. The composition comprises the combination of the active ingredients.

[0034] When used here the term “plant” includes reference to whole plants, plant organs (eg, leaves, stems, branches, roots, trunks, limbs, shoots, fruits, etc.) and propagating material or stem cells. plants

[0035] When used here, the term “plant” includes reference to agricultural crops including field crops (soybeans, corn, wheat, rice, etc.), vegetable crops (potatoes, cabbages, etc.), fruits (peach, etc. .), semi-perennial crops (sugar cane) and perennial crops (coffee and guava).

[0036] When used here, the term "propagating material" should be understood as denoting all the generating parts of the plant, such as seeds and spores, vegetative structures such as bulbs, rhizomes, basal shoots of plants, stolons and shoots.

[0037] When used here, the term “local” includes not only areas where weeds are already growing, but also areas where weeds have yet to appear, as well as cultivated areas.

[0038] When used here, the term “ha” refers to a hectare.

[0039] When used herein, the term "mixture" or "combination" refers to, but is not limited to, a combination in any physical form, for example, mixture, solution, alloy or similar.

[0040] When used here, the phrase “improving crop plants” means improving one or more of plant quality, plant vigor, nutrient absorption, root system, root resistance, tolerance to stress factors, and / or yield on a plant to which the mixture or composition described here was applied when compared to a control plant grown under the same conditions except that the mixture or composition described here was not applied.

[0041] When used here, the phrase "improving root system" means to qualitatively or quantitatively improve the root system. Improved root system includes, but is not limited to, improvement in the visual appearance and composition of the root system (ie, improvement in color, density, uniformity and visual appearance), improvement in root growth, a more developed root system, more roots stronger and healthier, improved plant support and increased weight of the root system.

[0042] When used here, the phrase “improving the quality of the plant” means that one or more traits are improved qualitatively or quantitatively. Such features include, but are not limited to, improvement of the visual appearance and composition of the plant (i.e., improvement of color, density, uniformity, compactness), reduced ethylene (reduced production and / or reception inhibition), improvement of visual appearance and composition of harvested material (ie, seeds, fruits, leaves, vegetables), improved carbohydrate content (ie, increased amounts of sugar and / or starch, improved sugar / acid ratio, reduced reducing sugars, increased rate of sugar development), improved protein content, improved composition and oil content, improved nutritional value, reduced anti-nutritional compounds, increased nutrient absorption, stronger and healthier roots, improved organoleptic properties (ie, improved taste), improved consumer health benefits (eg increased levels of vitamins and antioxidants), improved post-harvest characteristics (ie improved air time storage and / or storage stability, easier processability, easier extraction of compounds) and / or improved seed quality (that is, for use in the following seasons).

[0043] When used here, the term "plant growth regulation" includes restricting the vertical growth of the stem,

promote root growth, atrophy, increase the diameter of the stem and the thickness of the stem wall and the like.

[0044] When used here, the term plants ”refers to any and all physical parts of a plant, including, but not limited to, seeds, seedlings, shoots, roots, tubers, stems, foliage and fruits.

[0045] When used here, the term "surfactant" means an agriculturally acceptable material that confers emulsifiability, stability, spreading, wetting, dispersibility or other surface modifying properties. Examples of suitable surfactants include nonionic, anionic, cationic and ampholytic surfactants.

[0046] The terms "one" and "one" when used here include the singular and the plural, unless specifically stated to the contrary. Therefore, the terms "one", "one", "at least one" and "at least one" can be used in a manner that allows for exchange and / or replacement in this patent application.

[0047] From the beginning to the end of this patent application, the descriptions of several incorporations use the term "comprising"; however, a person skilled in the art will understand that in some specific cases, an incorporation can be described alternatively using the language "consisting essentially of" or "consisting of".

[0048] For the purpose of better understanding of the present teachings and without in any way limiting the scope of the teachings, unless otherwise indicated, all numbers expressing quantities, percentages or proportions, and other numerical values used in the specification and in the claims, will be understood to be modified in all cases by the term “about”. Consequently,

Unless otherwise indicated, the numerical parameters shown in the following specification and in the appended claims are approximations that may vary depending on the desired properties sought to be obtained. At a minimum, each numerical parameter must, at a minimum, be constructed in the light of the number of significant figures reported and applying usual rounding rules. In this regard, the use of the term "about" here specifically includes ± 10% of the values indicated in the range. In addition, the end points of all ranges relative to the same component or property here including the end points are independently combinable and include all intermediate points and ranges.

[0049] It should also be understood that when a parameter range is provided, all integers within that range and tenths of them, are also provided by the invention. For example, "0.1% to 50%" includes 0.1%, 0.2%, 0.3%, 0.4%, etc. up to 50%. Compositions

[0050] Fluensulfone, fipronil and azoxystrobin have been studied and used for many years. For many crops, there is a need for a combination of different pesticides to improve root development and rooting efficiency.

[0051] Preparing a ready-to-use stable composition comprising fluensulfone, fipronil and azoxystrobin is a challenge. Due to the solubility limitation, formulating fluensulfone, which requires an organic carrier, with fipronil and azoxystrobin requires an aqueous carrier, is challenging.

[0052] The present invention provides a stable composition comprising fluensulfone, fipronil and azoxystrobin.

[0053] The composition of the present invention is unexpectedly more efficient in controlling nematodes. The composition is also unexpectedly more efficient in regulating plant growth and improving plant development, including, for example, improving root development. The composition is ready to use after dilution.

[0054] The composition of the present invention provides a number of advantages over tank mixtures comprising fluensulfone, fipronil and azoxystrobin. These advantages include, but are not limited to, simplicity of use, stability, reduced amount of solvents and increased efficiency.

[0055] The present invention provides a stable broad-spectrum composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of an insecticide and (III) an effective amount of a fungicide.

[0056] The present invention provides a stable broad-spectrum composition ready to dilute comprising: (I) fluensulfone, (II) fipronil and (III) azoxystrobin.

[0057] In some incorporations, the fungicide is a strubilurine fungicide.

[0058] In some embodiments, the insecticide is a phenyl-pyrazole insecticide.

[0059] In some embodiments, the strubilurin fungicide is azoxystrobin.

[0060] In some embodiments, the phenyl-pyrazole insecticide is fipronil.

[0061] The present invention provides a stable composition comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0062] The present invention provides a stable broad-spectrum composition comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0063] The present invention provides a stable broad-spectrum composition for use in sugarcane, comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin .

The present invention provides a stable broad-spectrum composition comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin and (IV) an agriculturally acceptable carrier.

[0065] The present invention provides a stable composition comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) at least one physically stabilizing additive, (V ) an aqueous carrier and (VI) an organic carrier, where azoxystrobin and fipronil are suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier.

[0066] The present invention provides a stable composition comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) a physically stabilizing system, (V) an aqueous carrier and (VI) an organic carrier, with azoxystrobin and fipronil being suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier.

[0067] The present invention provides a stable composition comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an aqueous carrier and (V) a carrier organic, where azoxystrobin and fipronil are suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier.

[0068] The present invention provides a stable suspoemulsion composition comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an aqueous carrier and (V) an organic carrier, where azoxystrobin and fipronil are suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier.

[0069] The present invention provides a stable broad-spectrum composition for controlling pests, comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0070] The present invention provides a stable broad-spectrum composition ready to dilute, comprising (I) fluensulfone, (II) fipronil and (III) azoxystrobin.

[0071] The present invention provides a stable broad-spectrum composition ready to dilute, comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0072] The present invention provides a stable broad-spectrum composition ready to be diluted for use in sugarcane, comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount azoxystrobin.

[0073] The present invention provides a stable broad-spectrum composition ready to dilute, comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin and (IV) a carrier agriculturally acceptable.

[0074] The present invention provides a stable broad-spectrum composition ready to dilute, comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) at least a physically stabilizing additive, (V) an aqueous carrier and (VI) an organic carrier, with azoxystrobin and fipronil being suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier.

[0075] The present invention provides a stable broad-spectrum composition ready to dilute, comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) a system physically stabilizing, (V) an aqueous carrier and (VI) an organic carrier, with azoxystrobin and fipronil being suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier.

[0076] The present invention provides a stable broad-spectrum composition ready to dilute, comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) a carrier aqueous and (V) an organic carrier, with azoxystrobin and fipronil being suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier.

[0077] The present invention provides a stable broad-spectrum composition ready to dilute to control pests, comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0078] In some incorporations, pests are nematodes. In some incorporations, pests are insects. In some incorporations, pests are fungi. In some incorporations, the pests are nematodes, insects and fungi.

[0079] The present invention provides a stable composition for controlling nematodes, comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0080] The present invention provides a stable broad-spectrum composition for improving planting, comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0081] The present invention provides a stable broad-spectrum composition for improving plant development, comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0082] In some incorporations, the composition improves the development of the root. In some incorporations, the composition improves the plant's root system. In some incorporations, the composition improves the quality of the plant. In some incorporations, the composition improves the vigor of the plant. In some incorporations, the composition improves the yield of the plant. In some embodiments, the composition prevents root damage. In some incorporations, the composition improves rooting.

[0083] The present invention provides a stable broad-spectrum composition to regulate plant growth, comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0084] In some incorporations, the composition is ready to mix. In some incorporations, the composition is ready to dilute.

[0085] The present invention provides a stable broad-spectrum composition ready to mix to improve nematode control, improve root systems, improve the vigor and development of crop plants and improve the potential yield of the plant by preventing root damage and improving rooting, the composition comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0086] The present invention provides a stable composition ready for mixing comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0087] The present invention provides a stable ready-to-mix composition comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and

(III) an effective amount of azoxystrobin, with azoxystrobin and fipronil being suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier.

[0088] The present invention provides a stable ready-to-mix composition comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) at least one physically stabilizing additive , (V) an aqueous carrier and (VI) an organic carrier, where azoxystrobin and fipronil are suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier.

[0089] The present invention provides a stable composition ready for mixing comprising (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) a physically stabilizing system, ( V) an aqueous carrier and (VI) an organic carrier, with azoxystrobin and fipronil being suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier.

[0090] The present invention provides a stable broad-spectrum composition ready to mix, to improve root systems, improve the vigor and development of crop plants and improve the potential yield of the plant by preventing root damage and improving rooting, the The composition comprises (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0091] In some incorporations, the total amount of fluensulfone, fipronil and azoxystrobin in the composition is greater than 200 g / L. In some embodiments, the total amount of fluensulfone, fipronil and azoxystrobin in the composition is greater than 300 g / L. In some embodiments, the total amount of fluensulfone, fipronil and azoxystrobin in the composition is e 200 g / L to 500 g / L.

[0092] In some embodiments, fluensulfone is at least 30% by weight of the organic carrier.

[0093] In some embodiments, fluensulfone is at least 40% by weight of the organic carrier.

[0094] In some embodiments, fluensulfone is at least 50% by weight of the organic carrier.

[0095] In some embodiments, the composition comprises a stable ratio of ingredients.

[0096] In some embodiments, the composition comprises an aqueous carrier.

[0097] In some incorporations, fipronil is suspended in the aqueous carrier.

[0098] In some embodiments, azoxystrobin is suspended in the aqueous carrier.

[0099] In some incorporations, the composition comprises an organic carrier.

[0100] In some incorporations, fluensulfone is dissolved in the organic carrier.

[0101] In some incorporations, the composition is a suspoemulsion. In some embodiments, the composition is a suspoemulsion comprising an organic carrier. In some incorporations, in the suspoemulsion, fluensulfone is dissolved in the organic carrier.

[0102] In some embodiments, the composition is a suspoemulsion comprising an aqueous carrier and an organic carrier, with azoxystrobin and fipronil being suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier.

[0103] In some embodiments, fluensulfone is at least 30% by weight of the organic carrier.

[0104] In some embodiments, fluensulfone is at least 40% by weight of the organic carrier.

[0105] In some embodiments, fluensulfone is at least 50% by weight of the organic carrier.

[0106] In some embodiments, the organic carrier is an amide.

[0107] In some embodiments, the organic carrier is a fatty acid amide.

[0108] In some embodiments, the fatty acid amide is selected from the group consisting of C6-C18 carboxylic acid alkylamines and C6-C18 carboxylic acid alkanolamines.

[0109] In some embodiments, the organic carrier is a derivative of fatty acid amide. In some embodiments, the fatty acid amide derivative is selected from the group consisting of alkylamines and alkanolamines of C6-C18 carboxylic acids.

[0110] In some embodiments, the fatty acid amide is a derivative of N, N-dialkyl fatty acid amide. In some embodiments, the N, N-dialkyl fatty acid derivative is C10 fatty acid dimethylamide. In some embodiments, the fatty acid amide is N, N-dialkyl fatty acid amide. In some embodiments, the fatty acid amide is N, N-dimethyl-decanamide.

[0111] In some embodiments, the organic carrier is Genagen® 4296. Genagen® 4296 is a dimethylamide based on fatty acids derived naturally from Clariant.

[0112] In some embodiments, the organic carrier is an amide solvent. In some embodiments the amide solvent is derived from N, N-dialkyl fatty acid amide. In some embodiments, the amide solvent is N, N-dimethyl-decanamide. In some embodiments, the solvent is Genagen®

4296. Genagen® 4296 is a dimethylamide based on fatty acids derived naturally from Clariant.

[0113] In some embodiments, the composition comprises at least one physically stabilizing additive. In some embodiments, the composition comprises a physically stabilizing system.

[0114] In some embodiments, the physically stabilizing system is a combination of polyvinylpyrrolidone and poly (alkylene oxide) block copolymer.

[0115] In some embodiments, the physically stabilizing additive is polyvinylpyrrolidone. In some embodiments, the physically stabilizing additive is a block copolymer of poly (alkylene oxide). In some embodiments, the physically stabilizing additives are polyvinylpyrrolidone and a block copolymer of poly (alkylene oxide).

[0116] In some embodiments, the block copolymer of poly (alkylene oxide) is a copolymer in diblocks.

[0117] In some embodiments, the block copolymer of poly (alkylene oxide) is a copolymer in triblocks.

[0118] Poly (alkylene oxide refers to, poly (ethylene oxide), poly (propylene oxide), poly (butylene oxide) and a combination thereof.

[0119] In some embodiments, the block copolymer of poly (alkylene oxide) is dialkylated.

[0120] In some embodiments, the block copolymer of poly (alkylene oxide) is poloxamer.

[0121] In some embodiments, the copolymer in triblocks is poly (ethylene oxide) / poly (propylene oxide) / poly (ethylene oxide).

[0122] In some embodiments, the block copolymer of poly (alkylene oxide) is SYNPERONIC PE / F 68.

[0123] In some embodiments, polyvinylpyrrolidone is PVP K-30.

[0124] In some embodiments, the composition comprises at least one agriculturally acceptable carrier.

[0125] In some embodiments, the composition further comprises one or more components including, but not limited to, solvents, solubilizers and surfactants.

[0126] In some incorporations, the composition requires a lower amount of solvents than known tank mixes.

[0127] In an embodiment, the composition comprises fluensulfone in an amount ranging from about 1% to 60% by weight based on the total weight of the composition, preferably from about 5% to 40% by weight based on the total weight of the composition, preferably from about 5% to 30% by weight based on the total weight of the composition, more preferably from about 10% to 20% by weight based on the total weight of the composition, and most preferably from about 14% to 18% by weight based on the total weight of the composition.

[0128] In some embodiments, the composition comprises fluensulfone in an amount of about 15% by weight based on the total weight of the composition.

[0129] In some embodiments, the composition comprises fluensulfone in an amount of about 16% by weight based on the total weight of the composition.

[0130] In some embodiments, the composition comprises fipronil in an amount ranging from about 1% to 50% by weight based on the total weight of the composition, preferably from about 1% to 40% by weight based on the total weight of the composition, preferably from about 3% to 20% by weight based on the total weight of the composition, more preferably from about 4% to 8% by weight based on the total weight of the composition, more preferably from about 5% to 7% by weight based on the total weight of the composition.

[0131] In some embodiments, the composition comprises fipronil in an amount of about 6% by weight based on the total weight of the composition.

[0132] In some embodiments, the composition comprises fipronil in an amount of about 6.4% by weight based on the total weight of the composition.

[0133] In an embodiment, the composition comprises azoxystrobin in an amount ranging from about 0.1% to 50% by weight based on the total weight of the composition, preferably from about 0.1% to 20% by weight based on the total weight of the composition. composition, preferably from about 0.5% to 10% by weight based on the total weight of the composition, preferably from about 1% to 5% by weight based on the total weight of the composition, preferably from about 1.5% to 3 % by weight based on the total weight of the composition.

[0134] In some embodiments, the composition comprises azoxystrobin in an amount of about 1.8% by weight based on the total weight of the composition.

[0135] In some embodiments, the composition comprises azoxystrobin in an amount of about 1.9% by weight based on the total weight of the composition.

[0136] In some embodiments, the composition comprises azoxystrobin in an amount of about 1.86% by weight based on the total weight of the composition.

[0137] In some embodiments, the composition comprises a stable weight ratio of ingredients. In some embodiments, the weight ratio of fluensulfone to fipronil in the composition is about 5: 1, preferably about 3: 1, more preferably about 2.5: 1. In some embodiments, the weight ratio of fluensulfone to fipronil is about 5: 1 to about 1: 1.

[0138] In some embodiments, the composition comprises a stable weight ratio of ingredients. In some embodiments, the weight ratio of fluensulfone to azoxystrobin in the composition is about 20: 1, preferably about 10: 1, more preferably about 8.5: 1. In some embodiments, the weight ratio of fluensulfone to azoxystrobin is from about 20: 1 to about 1.5: 1.

[0139] In some embodiments, the composition comprises a stable weight ratio of ingredients. In some embodiments, the weight ratio of fipronil to azoxystrobin in the composition is about 7: 1, preferably about 5: 1, more preferably about 3.4: 1. In some embodiments, the weight ratio of fipronil to azoxystrobin is about 8: 1 to about 1: 1.

[0140] In some embodiments, the composition comprises a stable weight ratio of ingredients. In some embodiments, the weight ratio of fluensulfone to fipronil to azoxystrobin in the composition is about 8.5: 3.4: 1.

[0141] In some embodiments, the composition comprises a stable weight ratio of ingredients. In some embodiments, the weight ratio of fluensulfone to the combination of fipronil and azoxystrobin in the composition is from about 4: 1 to about 1: 1.

[0142] In some incorporations, the composition is liquid.

[0143] In some embodiments, the composition comprises fluensulfone in an amount ranging from about 10 to 600 g / L, preferably from about 50 to 400 g / L, preferably from about 50 to 300 g / L, more preferably from about from 100 to 200 g / L and most preferably from about 140 to 180 g / L. In some embodiments, the composition comprises fluensulfone in an amount of about 150 g / L. In some embodiments, the composition comprises fluensulfone in an amount of about 160 g / L.

[0144] In some embodiments, the composition comprises fipronil in an amount ranging from about 10 to 500 g / L, preferably from about 10 to 400 g / L, preferably from about 30 to 200 g / L, more preferably from about from 40 to 80 g / L, more preferably from about 50 to 70 g / L. In some embodiments, the composition comprises fipronil in an amount of about 60 g / L. In some embodiments, the composition comprises fipronil in an amount of about 64 g / L.

[0145] In some embodiments, the composition comprises azoxystrobin in an amount ranging from about 1 to 500 g / L, preferably from about 1 to 200 g / L, preferably from about 5 to 100 g / L, preferably from about 10 to 50 g / L, preferably about 15 to 30 g / L. In some embodiments, the composition comprises azoxystrobin in an amount of about 18 g / L. In some embodiments, the composition comprises azoxystrobin in an amount of about 19 g / L.

[0146] In an embodiment, the composition comprises fluensulfone in an amount ranging from about 130 g to about 300 g, preferably in an amount of about 160 g.

[0147] In some embodiments, the composition comprises fluensulfone in an amount ranging from about 100 g to about 300 g.

[0148] In some embodiments, the composition comprises fipronil in an amount ranging from about 40 g to about 80 g, preferably in an amount of about 64 g.

[0149] In some embodiments, the composition comprises azoxystrobin in an amount ranging from about 10 g to about 30 g, preferably in an amount of about 19 g.

[0150] In some embodiments, the composition comprises (I) 160 g of fluensulfone, (II) 64 g of fipronil and (III) 19 g of azoxystrobin.

[0151] In some embodiments, the composition comprises fluensulfone in an amount ranging from about 130 g / L to about 300 g / L, preferably in an amount of about 160 g / L.

[0152] In some embodiments, the composition comprises fipronil in an amount ranging from about 40 g / L to about 80 g / L, preferably in an amount of about 64 g / L.

[0153] In some embodiments, the composition comprises azoxystrobin in an amount ranging from about 10 g / L to about 30 g / L, preferably in an amount of about 19 g / L.

[0154] In some embodiments, the present invention provides a composition comprising: (a) from 100 to 300 g / L of fluensulfone; (b) from 40 to 80 g / L of fipronil and (c) from 10 to 30 g / L of azoxystrobin, with the total amount of fluensulfone, fipronil and azoxystrobin being greater than 200 g / L.

[0155] The present invention provides a stable broad-spectrum composition comprising: (I) 160 g / L of fluensulfone, (II) 64 g / L of fipronil and (III) 19 g / L of azoxystrobin.

[0156] In an embodiment, the amount of physically stabilizing additive in the composition ranges from about 1% to about 5% by weight based on the total weight of the composition.

[0157] In an embodiment, the amount of polyvinylpyrrolidone in the composition ranges from about 1% to about 5% by weight based on the total weight of the composition.

[0158] In some embodiments, the amount of polyvinylpyrrolidone in the composition is about 1.4% by weight based on the total weight of the composition.

[0159] In an embodiment, the amount of poly (alkylene oxide) block copolymer in the composition ranges from about 1% to about 5% by weight based on the total weight of the composition.

[0160] In one embodiment, the amount of poly (alkylene oxide) block copolymer in the composition is about

2.8% by weight based on the total weight of the composition.

[0161] In an embodiment, the total amount of physically stabilizing system in the composition ranges from about 2% to about 10% by weight based on the total weight of the composition, more preferably it is about 4.2% by weight based on the weight total composition.

[0162] In some embodiments, the composition comprises at least one additional solvent.

[0163] In some embodiments, the total amount of organic carrier in the composition ranges from about 5% to about 50% by weight based on the total weight of the composition, preferably about 20% by weight based on the total weight of the composition, more preferably about 15% by weight based on the total weight of the composition.

[0164] In some embodiments, the total amount of aqueous carrier in the composition ranges from about 10% to about 70% by weight based on the total weight of the composition, preferably from about 20% to about 60% by weight based on total weight of the composition, more preferably about 50% by weight based on the total weight of the composition.

[0165] In a further embodiment, the composition comprises one or more additional surfactants, which may include, but are not limited to, alkali metal, alkaline earth metal and ammonium salts of aromatic sulfonic acids, such as lignisulfonic acid, phenol sulfonic acid , naphthalene sulfonic acid, dibutyl naphthalene sulfonic acid, and fatty acids, alkyl sulfonates, alkyl aryl sulfonates, alkyl sulfates, lauryl ether sulfates, fatty alcohol sulfates, and sulfated hexa-, hepta- and octa-decanolates , glycol sulfated fatty alcohol ethers, in addition condensed with naphthalene or naphthalene sulfonic acid with phenol and formaldehyde, polyoxyethylene octyl-phenyl ether, isoctyl-phenol ethoxylated, octyl-phenol, nonyl-phenol, alkyl-phenyl-polyglycol ethers, tributyl-phenyl-phenyl polyglycol ether, tristearyl phenyl polyglycol ether, polyglycol isotridecyl alcohol ether (GENAPOL® x-080, Clariant, Switzerland), alkoxylated fatty alcohols, alkoxylated alcohol ethers, aryl alkyl alcohols polyethers, alcohol condensates and fatty alcohol / ethylene oxide, castor oil ethoxylate (EMULSOGEN® el-400, Clariant, Switzerland), tallow amine ethoxylate (TERWET® 3780, Huntsman, USA), epoxidized vegetable oils, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylene, ethoxylated polysorbate, polyglycol ether lauryl alcohol acetal, sorbitol esters, liquid lignin-sulfite residues and proteins, denatured proteins, polysaccharides (eg methyl cellulose), hydrophobically modified starches, poly (vinyl alcohol) ), polycarboxylates, polyalkoxylates, polyvinylamine, dodecylbenzene isopropylamine sulfonate (LIBRAMUL® IPA, Libra Specialty Chemicals, LTD, United Kingdom) and any salts thereof.

[0166] In a preferred embodiment, the composition is packaged in a single container and is ready to use directly after dilution.

[0167] The present invention provides a stable composition comprising (I) 160 g / L of fluensulfone, (II) 64 g / L of fipronil, (III) 19 g / L of azoxystrobin, (IV) 15 g / L of polyvinylpyrrolidone and (V) 30 g / L of poly (alkylene oxide) block copolymer, with azoxystrobin and fipronil being suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier.

[0168] The present invention provides a stable composition comprising (I) 160 g / L of fluensulfone, (II) 65 g / L of fipronil, (III) 19 g / L of azoxystrobin, (IV) 15 g / L of PVP K-30, (V) 30 g / L of Synperonic PE / F 68, (VI) an aqueous carrier and (VII) an organic carrier, with azoxystrobin and fipronil being suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier.

[0169] In some embodiments, the organic carrier is an amide.

[0170] In some embodiments, the organic carrier is a fatty acid amide.

[0171] In some embodiments, the fatty acid amide is selected from the group consisting of C6-C18 carboxylic acid alkylamines and C6-C18 carboxylic acid alkanolamines.

[0172] In some embodiments, the organic carrier is a derivative of fatty acid amide. In some embodiments, the fatty acid amide derivative is selected from the group consisting of alkylamines and alkanolamines of C6-C18 carboxylic acids.

[0173] In some embodiments, the fatty acid amide is a derivative of N, N-dialkyl fatty acid amide. In some embodiments, the N, N-dialkyl fatty acid derivative is C10 fatty acid dimethylamide. In some embodiments, the fatty acid amide is N, N-dialkyl fatty acid amide. In some embodiments, the fatty acid amide is N, N-dimethyl-decanamide.

[0174] In some embodiments, the organic carrier is Genagen® 4296. Genagen® 4296 is a dimethylamide based on fatty acids derived naturally from Clariant.

[0175] In some embodiments, the organic carrier is an amide solvent. In some embodiments the amide solvent is derived from N, N-dialkyl fatty acid amide. In some embodiments, the amide solvent is N, N-dimethyl-decanamide. In some embodiments, the solvent is Genagen®

4296. Genagen® 4296 is a dimethylamide based on fatty acids derived naturally from Clariant.

[0176] The present composition may further comprise one or more additional agriculturally acceptable additives known in the art including, but not limited to, solid diluents, liquid diluents, wetting agents, adhesives, thickening agents, antifoaming agent, preservatives, humectants, antioxidants, binders (binders), fertilizers or antifreeze agents. In addition, the present composition may also further include additional crop protection agents known in the art, for example, pesticides, phytoprotectors, agents to control fungi or phytopathogenic bacteria.

[0177] Antifoaming agents may include, but are not limited to, non-ionic aqueous polydimethylsiloxane emulsion.

[0178] Thickeners may include, but are not limited to, xanthan gum.

[0179] Antioxidant agents may include, but are not limited to, butylhydroxy-toluene.

[0180] The present composition can also comprise agriculturally additional adjuvant.

[0181] In some embodiments, the composition comprises sodium dioctyl sulfosuccinate. In some embodiments, the amount of sodium dioctyl sulfosuccinate in the composition is 0.1% to 1% by weight based on the total weight of the composition. In some embodiments, the amount of sodium dioctyl sulfosuccinate in the composition is 0.46% by weight based on the total weight of the composition.

[0182] In some embodiments, the composition comprises polydimethylsiloxanes. In some embodiments, the amount of polydimethylsiloxanes in the composition is 0.1% to 1% by weight based on the total weight of the composition. In some embodiments, the amount of polydimethylsiloxanes in the composition is 0.56% by weight based on the total weight of the composition.

[0183] In some embodiments, the composition comprises butylhydroxy-toluene. In some embodiments, the amount of butylhydroxy-toluene in the composition is 0.01% to 0.5% by weight based on the total weight of the composition. In some embodiments, the amount of butylhydroxy-toluene in the composition is 0.19% by weight based on the total weight of the composition.

[0184] In some incorporations, the composition comprises epoxidized soy oil. In some embodiments, the amount of epoxidized soy oil in the composition is 0.01% to 0.5% by weight based on the total weight of the composition. In some embodiments, the amount of epoxidized soybean oil in the composition is 0.19% by weight based on the total weight of the composition.

[0185] In some embodiments, the composition comprises N, N-dimethyl-decanamide. In some embodiments, the amount of N, N-dimethyl-decanamide in the composition is 1% to 30% by weight based on the total weight of the composition. In some embodiments, the amount of N, N-dimethyl-decanamide in the composition is 10% to 20% by weight based on the total weight of the composition. In some embodiments, the amount of N, N-dimethyl-decanamide in the composition is 13% to 16% by weight based on the total weight of the composition. In some embodiments, the amount of N, N-dimethyl-decanamide in the composition is 14.4% by weight based on the total weight of the composition.

[0186] In some embodiments, the composition comprises butyl block copolymer. In some embodiments, the amount of butyl block copolymer in the composition is 1% to 5% by weight based on the total weight of the composition. In some embodiments, the amount of butyl block copolymer in the composition is 2.8% by weight based on the total weight of the composition.

[0187] In some incorporations, the composition comprises xanthan gum. In some embodiments, the amount of xanthan gum in the composition is 0.01% to 0.5% by weight based on the total weight of the composition. In some embodiments, the amount of xanthan gum in the composition is 0.15% by weight based on the total weight of the composition.

[0188] In some embodiments, the composition comprises (benzyloxy) methanol. In some embodiments, the amount of (benzyloxy) methanol in the composition is 0.01% by weight based on the total weight of the composition.

[0189] In some embodiments, the composition comprises 1,2-benzisothiazolin-3-one / sodium hydroxide. In some embodiments, the amount of 1,2-benzisothiazolin-3-one / sodium hydroxide in the composition is 0.01% by weight based on the total weight of the composition.

[0190] In some incorporations, the composition comprises water. In some embodiments, the amount of water in the composition is 30% to 80% by weight based on the total weight of the composition. In some embodiments, the amount of water in the composition is 45% to 60% by weight based on the total weight of the composition. In some embodiments, the amount of water in the composition is 54% by weight based on the total weight of the composition.

[0191] The present invention also provides a stable composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of organic carrier and (V) water, where azoxystrobin and fipronil are suspended in water and fluensulfone is dissolved in the organic carrier.

[0192] The present invention also provides a stable composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of organic carrier and (V) water, where azoxystrobin and fipronil are suspended in water and fluensulfone is dissolved in the organic carrier.

[0193] The present invention also provides a stable composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of organic carrier and (V) water, the amount of fluensulfone in the organic carrier being at least 40% by weight of the organic carrier.

[0194] The present invention also provides a stable composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of organic carrier and (V) water, with azoxystrobin and fipronil being suspended in water and fluensulfone is dissolved in the organic carrier and that the amount of fluensulfone in the organic carrier is at least 40% by weight of the organic carrier.

[0195] The present invention also provides a stable composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of organic carrier and (V) water, the amount of fluensulfone in the organic carrier being at least 30% by weight of the organic carrier.

[0196] The present invention also provides a stable broad-spectrum composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of organic carrier and (V) water, with azoxystrobin and fipronil being suspended in water and fluensulfone is dissolved in the organic carrier and the amount of fluensulfone in the organic carrier is at least 30% by weight of the organic carrier.

[0197] The present invention also provides a stable composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of organic carrier and (V) water, the amount of fluensulfone in the organic carrier being at least 50% by weight of the organic carrier.

[0198] The present invention also provides a stable broad-spectrum composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of organic carrier and (V) water, with azoxystrobin and fipronil being suspended in water and fluensulfone is dissolved in the organic carrier and that the amount of fluensulfone in the organic carrier is at least 50% by weight of the organic carrier.

[0199] The present invention also provides a stable composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of polymer, ( V) an effective amount of organic carrier and (VI) water, where azoxystrobin and fipronil are suspended in water and fluensulfone is dissolved in the organic carrier.

[0200] The present invention also provides a stable broad-spectrum composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of polymer, (V) an effective amount of organic carrier and (VI) water, the amount of fluensulfone in the organic carrier being at least 40% by weight of the organic carrier.

[0201] The present invention also provides a stable broad-spectrum composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of polymer, (V) an effective amount of organic carrier and (VI) water, azoxystrobin and fipronil are suspended in water and fluensulfone is dissolved in the organic carrier and the amount of fluensulfone in the organic carrier is at least 40% in weight of the organic carrier.

[0202] The present invention also provides a stable broad-spectrum composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of polymer, (V) an effective amount of organic carrier and (VI) water, the amount of fluensulfone in the organic carrier being at least 30% by weight of the organic carrier.

[0203] The present invention also provides a stable broad-spectrum composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of polymer, (V) an effective amount of organic carrier and (VI) water, azoxystrobin and fipronil are suspended in water and fluensulfone is dissolved in the organic carrier and the amount of fluensulfone in the organic carrier is at least 30% in weight of the organic carrier.

[0204] The present invention also provides a stable broad-spectrum composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of polymer, (V) an effective amount of organic carrier and (VI) water, the amount of fluensulfone in the organic carrier being at least 50% by weight of the organic carrier.

[0205] The present invention also provides a stable broad-spectrum composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of polymer, (V) an effective amount of organic carrier and (VI) water, where azoxystrobin and fipronil are suspended in water and fluensulfone is dissolved in the organic carrier and that the amount of fluensulfone in the organic carrier is at least 50% in weight of the organic carrier.

[0206] In some embodiments, the organic carrier is an amide.

[0207] In some embodiments, the organic carrier is a fatty acid amide.

[0208] In some embodiments, the fatty acid amide is selected from the group consisting of C6-C18 carboxylic acid alkylamines and C6-C18 carboxylic acid alkanolamines.

[0209] In some embodiments, the organic carrier is a derivative of fatty acid amide. In some embodiments, the fatty acid amide derivative is selected from the group consisting of alkylamines and alkanolamines of C6-C18 carboxylic acids.

[0210] In some embodiments, the fatty acid amide is a derivative of N, N-dialkyl fatty acid amide. In some embodiments, the N, N-dialkyl fatty acid derivative is C10 fatty acid dimethylamide. In some embodiments, the fatty acid amide is N, N-dialkyl fatty acid amide. In some embodiments, the fatty acid amide is N, N-dimethyl-decanamide.

[0211] In some embodiments, the organic carrier is Genagen® 4296. Genagen® 4296 is a dimethylamide based on fatty acids derived naturally from Clariant.

[0212] In some embodiments, the organic carrier is an amide solvent. In some embodiments the amide solvent is derived from N, N-dialkyl fatty acid amide. In some embodiments, the amide solvent is N, N-dimethyl-decanamide. In some embodiments, the solvent is Genagen®

4296. Genagen® 4296 is a dimethylamide based on fatty acids derived naturally from Clariant.

[0213] The present invention also provides a stable broad-spectrum composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of polyvinylpyrrolidone, (V) an effective amount of N, N-dimethyl-decanamide and (VI) water.

[0214] The present invention also provides a stable broad-spectrum composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of polymer, (V) an effective amount of organic carrier and (VI) water.

[0215] The present invention also provides a stable broad-spectrum composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil, (III) an effective amount of azoxystrobin, (IV) an effective amount of polyvinylpyrrolidone, (V) an effective amount of N, N-dimethyl-decanamide and (VI) water.

[0216] In some embodiments, the weight ratio of fluensulfone to fipronil to azoxystrobin is about 8.5: 3.4: 1.

[0217] The present invention also provides a stable broad-spectrum composition comprising: (I) about 15% by weight of fluensulfone, (II) about 6% by weight of fipronil, (III) about 1.86% by weight weight of azoxystrobin, (IV) about 1.4% by weight of polyvinylpyrrolidone, (V) about 14.4% by weight of N, N-dimethyl-decanamide and (VI) 54% by weight of fresh water.

[0218] The present invention also provides a broad spectrum stable composition comprising: (I) 15% by weight of fluensulfone, (II) 6% by weight of fipronil, (III) 1.86% by weight of azoxystrobin, (IV ) 1.4% by weight of polyvinylpyrrolidone, (V) 2.8% by weight of poly (alkylene oxide) block copolymer, (VI) 0.46% by weight of sodium dioctyl sulfosuccinate, (VII) 0 , 56% polydimethylsiloxanes, (VIII) 0.19% by weight of butylhydroxy-toluene, (IX) 0.19% by weight of epoxidized soybean oil, (X) 14.4% by weight of N, N -dimethyl-decanamide, (XI) 2.8% by weight of butyl block copolymer, (XII) 0.15% by weight of xanthan gum, (XIII) 0.01% by weight of (benzyloxy) methanol, ( XIV) 0.01% by weight of 1,2-benzisothiazolin-3-one / sodium hydroxide and 54% by weight of fresh water.

[0219] In some embodiments, the composition comprises one or more additional active ingredients. In some embodiments, the composition comprises one or more additional non-active ingredients. Composition stabilization

[0220] It is a challenge to formulate a stable composition comprising three active ingredients, each requiring different and specific conditions of stability. The present composition is more challenging due to the limited solubility of fluensulfone in organic carriers and the variable solubility of fipronil, the organic carrier selected for the composition.

[0221] In the present invention, we have surprisingly discovered, without being limited to any hypothesis / assumption, that the combination of the active ingredients with polyvinylpyrrolidone and / or with poly (alkylene oxide) block copolymer reduces the interference between the active ingredients and improves composition stability.

[0222] Without limiting any theory, we formulate the hypothesis that polyvinylpyrrolidone is absorbed by the fipronil particle and reduces the solubility of fipronil in the organic carrier. In addition, the organic carrier can also stabilize and be covered by poly (alkylene oxide) block copolymer.

[0223] The present invention also provides for the use of polyvinylpyrrolidone to stabilize a composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0224] The present invention also provides for the use of polyvinylpyrrolidone to stabilize a suspoemulsion composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0225] The present invention also provides for the use of a combination of polyvinylpyrrolidone and poly (alkylene oxide) block copolymer to stabilize a suspoemulsion composition comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin. Mixture of fluensulfone, fipronil and azoxystrobin, and use thereof

[0226] The present invention provides a pesticidal mixture comprising any of the compositions disclosed herein.

[0227] The present invention provides a pesticidal mixture for use in sugarcane, the pesticidal mixture comprising any of the compositions disclosed herein.

[0228] The present invention provides a pesticidal mixture for use in sugarcane, the pesticidal mixture comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount azoxystrobin.

[0229] The present invention provides a pesticidal mixture comprising: (I) 160 g / L of fluensulfone, (II) 64 g / L of fipronil and (III) 19 g / L of azoxystrobin.

[0230] The present invention provides an agricultural mixture comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0231] The present invention provides an agricultural mixture comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin, the weight ratio of fluensulfone to fipronil to azoxystrobin is about 8.5: 3.4: 1.

[0232] The present invention provides an agricultural mixture comprising: (I) fluensulfone, (II) fipronil and (III)

azoxystrobin in a weight ratio of about 8.5: 3.4: 1.

[0233] The present invention provides an agricultural mixture comprising: (I) 160 g / L of fluensulfone, (II) 64 g / L of fipronil and (III) 19 g / L of azoxystrobin.

[0234] The present invention provides an agricultural mixture comprising: (I) 160 g of fluensulfone, (II) 64 g of fipronil and (III) 19 g of azoxystrobin.

[0235] The present invention provides an agricultural mixture, for use in sugarcane, comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0236] The present invention provides an agricultural mixture, for use in sugarcane, comprising: (I) fluensulfone, (II) fipronil and (III) azoxystrobin in a weight ratio of about 8.5: 3.4: 1.

[0237] The present invention provides an agricultural mixture, for use in sugarcane, comprising: (I) 160 g of fluensulfone, (II) 64 g of fipronil and (III) 19 g of azoxystrobin.

[0238] The present invention provides an agricultural mixture, for use in sugarcane, comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin, and the weight ratio of fluensulfone to fipronil to azoxystrobin is about 8.5: 3.4: 1.

[0239] The present invention provides an agricultural mixture, for use in sugarcane, comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin, and the weight ratio of fluensulfone to fipronil and azoxystrobin is about 4: 1 to 1: 1.

[0240] The present invention provides an agricultural mixture, for use in sugarcane, comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin, and the weight ratio of fluensulfone to fipronil and azoxystrobin is about 2: 1.

[0241] The present invention provides an agricultural mixture, for use in sugarcane, comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin, and the weight ratio of fluensulfone to fipronil and azoxystrobin is about 1.93: 1.

[0242] The present invention provides an agricultural mixture, for use in sugarcane, comprising: (I) 160 g / L of fluensulfone, (II) 64 g / L of fipronil and (III) 19 g / L of azoxystrobin.

[0243] In some embodiments, the mixture comprises fluensulfone in an amount ranging from about 130 g to about 300 g, preferably in an amount of about 160 g.

[0244] In some embodiments, the mixture comprises: fluensulfone in an amount ranging from about 130 g to about 300 g.

[0245] In some embodiments, the mixture comprises fipronil in an amount ranging from about 40 g to about 80 g, preferably in an amount of about 64 g.

[0246] In an embodiment, the mixture comprises azoxystrobin in an amount ranging from about 10 g to about 30 g, preferably in an amount of about 19 g.

[0247] In some embodiments, the mixture comprises: (I) 160 g of fluensulfone, (II) 64 g of fipronil and (III) 19 g of azoxystrobin.

[0248] In some embodiments, the mixture comprises fluensulfone in an amount ranging from about 130 g / L to about 300 g / L, preferably in an amount of about 160 g / L.

[0249] In some embodiments, the mixture comprises fipronil in an amount ranging from about 40 g / L to about 80 g / L, preferably in an amount of about 64 g / L.

[0250] In some embodiments, the mixture comprises azoxystrobin in an amount ranging from about 10 g / L to about 30 g / L, preferably in an amount of about 19 g / L. In some embodiments, the mixture comprises azoxystrobin in an amount ranging from about 10 g / L to about 30 g / L.

[0251] In some embodiments, the present invention provides a mixture comprising: (a) 100 to 300 g of fluensulfone; (b) 40 to 80 g of fipronil; and (c) 10 to 30 g of azoxystrobin, the total amount of fluensulfone, fipronil and azoxystrobin being greater than 200 g.

[0252] In some embodiments, the present invention provides a mixture comprising: (a) from 100 g / L to 300 g / L of fluensulfone; (b) from 40 g / L to 80 g / L of fipronil; and (c) from 10 g / L to 30 g / L of azoxystrobin, the total amount of fluensulfone, fipronil and azoxystrobin being greater than 200 g / L.

[0253] In some incorporations, the mixture comprises: (I)

160 g / L of fluensulfone, (II) 64 g / L of fipronil and (III) 19 g / L of azoxystrobin.

[0254] In some embodiments, the mixture comprises a stable weight ratio of ingredients. In some embodiments, the weight ratio of fluensulfone to fipronil in the mixture is about 5: 1, preferably about 3: 1, more preferably about 2.5: 1. In some embodiments, the weight ratio of fluensulfone to fipronil is about 5: 1 to about 1: 1.

[0255] In some embodiments, the mixture comprises a stable weight ratio of ingredients. In some embodiments, the weight ratio of fluensulfone to azoxystrobin in the mixture is about 10: 1, preferably about 10: 1, more preferably about 8.5: 1. In some embodiments, the weight ratio of fluensulfone to azoxystrobin is from about 20: 1 to about 1.5: 1.

[0256] In some embodiments, the mixture comprises a stable weight ratio of ingredients. In some embodiments, the weight ratio of fipronil to azoxystrobin in the mixture is about 7: 1, preferably about 5: 1, more preferably about 3.4: 1. In some embodiments, the weight ratio of fipronil to azoxystrobin is about 8: 1 to about 1: 1.

[0257] In some embodiments, the mixture comprises a stable weight ratio of ingredients. In an embodiment, the weight ratio of fluensulfone to fipronil to azoxystrobin in the mixture is about 8.5: 3.4: 1.

[0258] In some embodiments, the mixture comprises an effective weight ratio of ingredients. In an embodiment, the weight ratio of fluensulfone to fipronil in the mixture is about 5: 1, preferably about 3: 1, more preferably about 2.5: 1. In some embodiments, the weight ratio of fluensulfone to fipronil in the mixture is about 5: 1 to about 1: 1.

[0259] In some embodiments, the mixture comprises an effective weight ratio of ingredients. In an embodiment, the weight ratio of fluensulfone to azoxystrobin in the mixture is about 20: 1, preferably about 10: 1, more preferably about 8.5: 1. In some embodiments, the weight ratio of fluensulfone to azoxystrobin in the mixture is about 20: 1 to about 1.5: 1.

[0260] In some embodiments, the mixture comprises an effective weight ratio of ingredients. In some embodiments, the weight ratio of fipronil to azoxystrobin in the mixture is about 7: 1, preferably about 5: 1, more preferably about 3.4: 1. In some embodiments, the weight ratio of fipronil to azoxystrobin in the mixture is about 8: 1 to about 1: 1.

[0261] In some embodiments, the mixture comprises an effective weight ratio of ingredients. In some embodiments, the weight ratio of fluensulfone to fipronil to azoxystrobin in the mixture is about 8.5: 3.4: 1.

[0262] In some embodiments, the mixture comprises an effective weight ratio of ingredients. In some embodiments, the weight ratio of fluensulfone to the combination of fipronil and azoxystrobin in the mixture is about 4: 1 to about 1: 1.

[0263] In some embodiments, the effective weight ratio refers to the weight ratio in which the efficacy of fluensulfone to control nematodes is improved and / or in which the development of the plant is improved, where the improved development of the plant includes, but does not it is limited to improved root systems and / or crop plant sprout and / or potential yield of the plant.

[0264] It has been found that by combining fluensulfone with fipronil and azoxystrobin, the effectiveness of fluensulfone to control nematodes is improved. It has also been found that applying a composition comprising fluensulfone, fipronil and azoxystrobin improves plant development, including, but not limited to, improving plant root systems and / or crop and / or plant vigor and / or yield potential of the plant.

[0265] In some incorporations, the vigor of the plant is evaluated using the relative vigor index. In some incorporations, the vigor of the plant increases by at least 1%, 5%, 10, 20%, 30%, 40%, 50%, 60%, 70%, 80%, or 90%.

[0266] In some incorporations, the improvement in the root system is measured by the weight of the root. In some incorporations, the root weight increases by at least 1%, 5%, 10, 20%, 30%, 40%, 50%, 60%, 70%, 80%, or 90%.

[0267] In some incorporations, the improvement in shoot is measured by the weight of the shoot. In some incorporations, the shoot weight increases by at least 1%, 5%, 10, 20%, 30%, 40%, 50%, 60%, 70%, 80%, or 90%.

[0268] The present invention provides a mixture comprising: (I) an amount of fluensulfone, (II) an amount of fipronil and (III) an amount of azoxystrobin.

[0269] In some incorporations, when the amount of fluensulfone, the amount of fipronil and the amount of azoxystrobin are applied together, greater efficacy occurs than when the same amount is applied to each agent alone.

[0270] In some embodiments, the amount of fluensulfone in the mixture is less than the amount effective as a pesticide than when fluensulfone is applied alone.

[0271] In some embodiments, the amount of fipronil in the mixture is less than the amount effective as a pesticide than when applying fipronil alone.

[0272] In some embodiments, the amount of azoxystrobin in the mixture is less than the amount effective as a pesticide than when applying azoxystrobin alone.

[0273] The present invention provides a synergistic mixture comprising: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin.

[0274] In some embodiments, in the synergistic mixture, the weight ratio of fluensulfone to fipronil to azoxystrobin is about 8.5: 3.4: 1.

[0275] In some embodiments, in the synergistic mixture, the weight ratio of fluensulfone to fipronil is about 5: 1, preferably about 3: 1, more preferably about 2.5: 1.

[0276] In some embodiments, in the synergistic mixture, the weight ratio of fluensulfone to azoxystrobin in the mixture is about 20: 1, preferably it is about 10: 1, more preferably it is about 8.5: 1.

[0277] In some embodiments, in the synergistic mixture, the weight ratio of fipronil to azoxystrobin is about 7: 1, preferably it is about 5: 1, more preferably it is about 3.4: 1.

[0278] In some embodiments, the synergistic mixture or mixture comprises one or more additional active ingredients. In some embodiments, the synergistic blend or blend comprises one or more additional non-active ingredients.

[0279] There is a synergistic effect whenever the action of a combination of active ingredients is greater than the sum of the actions of the individual components.

[0280] In some incorporations, the mixture is synergistic to improve planting. In some incorporations, the mixture is synergistic to improve the development of the plant. In some incorporations, the mixture is synergistic to improve the root system. In some incorporations, the mixture is synergistic to improve the quality of the plant. In some incorporations, the mixture is synergistic to regulate the growth of the plant. In some incorporations, the mixture is synergistic to control nematodes.

[0281] In the field of agriculture, it is often understood that the term “synergy” is as defined by Colby S.R. in an article entitled “Calculation of synergistic and antagonistic responses of herbicidal combinations” published in the journal Weeds, 1967, 15, p. 20-22. The expected action for a given combination of two active components can be calculated as follows: E = X + Y - XY / 100

[0282] The expected action for a given combination of three active components can be calculated as follows: E = X + Y + Z - (XY + XZ + YZ) / 100 + XYZ / 10000 where E represents the expected effect, for example, percentage of pest control, for the combination of the three active ingredients in defined doses (for example, equal to x, y and z,

respectively), X is the effect, for example, percentage of pest control, observed for compound (I) at a defined dose (equal to x), Y is the effect, for example, percentage of pest control, observed for compound (II) at a defined dose (equal to y), Z is the effect, for example, percentage of pest control, observed for compound (III) at a defined dose (equal to z). When the effect, for example, percentage of pest control, observed for the combination is greater than the expected effect, there is a synergistic effect.

[0283] In some incorporations, the mixture comprises an organic carrier.

[0284] In some embodiments, the organic carrier is an amide.

[0285] In some embodiments, the organic carrier is a fatty acid amide.

[0286] In some embodiments, the fatty acid amide is selected from the group consisting of C6-C18 carboxylic acid alkylamines and C6-C18 carboxylic acid alkanolamines.

[0287] In some embodiments, the organic carrier is a derivative of fatty acid amide. In some embodiments, the fatty acid amide derivative is selected from the group consisting of alkylamines and alkanolamines of C6-C18 carboxylic acids.

[0288] In some embodiments, the fatty acid amide is a derivative of N, N-dialkyl fatty acid amide. In some embodiments, the N, N-dialkyl fatty acid derivative is C10 fatty acid dimethylamide. In some embodiments, the fatty acid amide is N, N-dialkyl fatty acid amide. In some embodiments, the fatty acid amide is N, N-dimethyl-decanamide.

[0289] In some embodiments, the organic carrier is Genagen® 4296. Genagen® 4296 is a dimethylamide based on fatty acids derived naturally from Clariant.

[0290] In some embodiments, the organic carrier is an amide solvent. In some embodiments the amide solvent is derived from N, N-dialkyl fatty acid amide. In some embodiments, the amide solvent is N, N-dimethyl-decanamide. In some embodiments, the solvent is Genagen®

4296. Genagen® 4296 is a dimethylamide based on fatty acids derived naturally from Clariant.

[0291] In some embodiments, the mixture comprises at least one physically stabilizing additive.

[0292] In some embodiments, the mixture comprises a physically stabilizing system.

[0293] In some embodiments, the physically stabilizing system is a combination of polyvinylpyrrolidone and poly (alkylene oxide) block copolymer.

[0294] In some embodiments, the physically stabilizing additive is polyvinylpyrrolidone. In some embodiments, the physically stabilizing additive is a block copolymer of poly (alkylene oxide). In some embodiments, the physically stabilizing additives are polyvinylpyrrolidone and a block copolymer of poly (alkylene oxide).

[0295] In some embodiments, the block copolymer of poly (alkylene oxide) is a copolymer in diblocks.

[0296] In some embodiments, the block copolymer of poly (alkylene oxide) is a copolymer in triblocks.

[0297] Poly (alkylene oxide) block copolymer refers to poly (ethylene oxide), poly (propylene oxide), poly (butylene oxide) and a combination thereof.

[0298] In some embodiments, the block copolymer of poly (alkylene oxide) is alkylated.

[0299] In some embodiments, the block copolymer of poly (alkylene oxide) is dialkylated.

[0300] In some embodiments, the block copolymer of poly (alkylene oxide) is poloxamer.

[0301] In some embodiments, the copolymer in triblocks is poly (ethylene oxide) / poly (propylene oxide) / poly (ethylene oxide).

[0302] In some embodiments, the physically stabilizing system is a combination of polyvinylpyrrolidone and a block copolymer of poly (alkylene oxide).

[0303] In some embodiments, the block copolymer of poly (alkylene oxide) is Synperonic PE / F 68.

[0304] In some embodiments, polyvinylpyrrolidone is PVP K-30.

[0305] The mixtures described herein can be a tank mix or a diluted form of any of the compositions described here.

[0306] In some incorporations, the mixture is a tank mixture.

[0307] In some embodiments, the mixture comprises any of the compositions described here, in which the composition is diluted.

[0308] The present invention also contemplates methods for preparing a mixture comprising (I) fluensulfone, (II) fipronil, (III) azoxystrobin, (IV) an organic carrier and (V) a physically stabilizing additive, the method comprising mixing fluensulfone, fipronil, azoxystrobin, an organic carrier and a physically stabilizing additive, in any order, to obtain the mixture. Method of use

[0309] The present invention provides a method for controlling nematodes comprising applying an effective amount of any of the compositions or mixtures disclosed herein to one or more plants, at the site of them or their propagating material in order to improve thus the control of nematodes.

[0310] The present invention provides a method for improving nematode control comprising applying an effective amount of any of the compositions or mixtures disclosed herein to one or more plants, at the site of them or their propagating material in order to improve thus nematode control.

[0311] The present invention provides a method for improving root systems and / or improving the development of cultivated plants and / or improving the vigor of cultivated plants and / or improving plant potential comprising applying an effective amount of any of the compositions or mixtures herein. disseminated in one or more plants, in the location of the same or propagating material of the same.

[0312] The present invention provides a method for improving the development of plants comprising applying an effective amount of any of the compositions or mixtures disclosed herein to one or more plants, at the site of them or their propagating material in order to improve as well the development of the plant.

[0313] The present invention provides a method for improving the root system comprising applying an effective amount of any of the compositions or mixtures disclosed herein to one or more plants, at the site of them or their propagating material in order to improve thus the root system.

[0314] The present invention provides a method for improving the vigor of plants comprising applying an effective amount of any of the compositions or mixtures disclosed herein to one or more plants, at the site of them or their propagating material in order to improve thus the vigor of the plant.

[0315] The present invention provides a method for improving the potential yield of plants comprising applying an effective amount of any of the compositions or mixtures disclosed herein to one or more plants, at their location or propagating material in order to improve thus the potential yield of the plant.

[0316] The present invention provides a method for regulating the growth of plants comprising applying an effective amount of any of the compositions or mixtures disclosed herein to one or more plants, at the site of them or their propagating material in order to regulate so the development of the plant.

[0317] The present invention provides a method for controlling nematodes comprising applying (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin to one or more plants, at the site of the same or in their propagation material so as to control nematodes.

[0318] The present invention provides a method for improving nematode control comprising applying (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin on one or more plants, in the their location or in their propagation material so as to improve nematode control.

[0319] The present invention provides a method for improving crop plant comprising applying (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin to one or more plants, at the site of the same or in the propagation material of them in order to improve the cultivation plant.

[0320] The present invention provides a method for improving plant development comprising applying (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin to one or more plants, in the their location or in their propagation material in order to improve the control of the plant.

[0321] In some incorporations, improving plant development involves improving the root system. In some incorporations, improving plant development involves improving the vigor of the plant. In some incorporations, improving plant development involves improving the potential yield of the plant. In some incorporations, improving plant development involves improving potential yield.

[0322] In some incorporations, the method improves root development. In some incorporations, the method improves the plant's root system. In some incorporations, the method improves the quality of the plant. In some incorporations, the method improves the vigor of the plant. In some incorporations, the method improves the yield of the plant. In some embodiments, the method prevents damage to the root. In some incorporations, the method improves rooting.

[0323] The present invention provides a method for regulating plant growth comprising applying (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin to one or more plants, in the their location or in their propagation material in order to regulate the growth of the plant.

[0324] In some incorporations, plant vigor is assessed using the relative vigor index. In some incorporations, plant vigor increases by at least 1%, 5%, 10, 20%, 30%, 40%, 50%, 60%, 70%, 80%, or 90%.

[0325] In some incorporations, the improvement in the root system is measured by the root weight. In some incorporations, the root weight increases by at least 1%, 5%, 10, 20%, 30%, 40%, 50%, 60%, 70%, 80%, or 90%.

[0326] In some incorporations, sapling improvement is measured by the sapling weight. In some incorporations, the root weight increases by at least 1%, 5%, 10, 20%, 30%, 40%, 50%, 60%, 70%, 80%, or 90%.

[0327] The present invention provides a method for preventing plant and / or soil disease comprising applying an amount of any of the mixtures or compositions disclosed herein to one or more plants, at their location or in their propagation material in a manner to prevent plant and / or soil disease.

[0328] The present invention provides a method for controlling plant and / or soil disease comprising applying an effective amount of any of the mixtures or compositions disclosed herein to one or more plants, at their location or in their propagating material. to control plant and / or soil disease.

[0329] The present invention provides a method for controlling plant and / or soil disease comprising applying (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin in one or more plants, in their location or in their propagation material in order to prevent plant and / or soil disease.

[0330] The present invention provides a method for preventing plant and / or soil disease comprising applying (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin in one or more plants, in their location or in their propagation material in order to prevent plant and / or soil disease.

[0331] The methods of the present invention pertain to any plant and / or soil disease including, but not limited to, sugar cane weevil (Sphenophorus levis), lesion nematode (Pratylenchus zeae), node nematode root (Meloidogyne javanica), black root rot (Thielaviopsis paradoxa), Heterotermes tenuis and Ceratocystis paradoxa.

[0332] In some embodiments, the method is effective on plants and / or root systems affected by plant and / or soil diseases including, but not limited to, sugarcane weevil (Sphenophorus levis), lesion nematode ( Pratylenchus zeae), root knot nematode (Meloidogyne javanica), black root rot (Thielaviopsis paradoxa), Heterotermes tenuis and Ceratocystis paradoxa.

[0333] In some embodiments, the method, mixtures and compositions disclosed herein are effective on plants and / or root systems affected by plant diseases and / or soils caused by sugar cane weevil (Sphenophorus levis), nematode lesion (Pratylenchus zeae), root knot nematode (Meloidogyne javanica), black root rot (Thielaviopsis paradoxa), Heterotermes tenuis and Ceratocystis paradoxa.

[0334] The methods of the present invention refer to any cultivated plants including, but not limited to monocots such as sugar cane, cereals, rice, corn and / or dicots such as beet; fruits (such as pome fruit, stone fruit or soft fruit, for example, apples, pears, plums, peaches, almonds, cherries, strawberries, raspberries or blackberries); leguminous plants (such as beans, lentils, peas or soybeans); oil plants (such as rapeseed, mustard, poppy, olives, sunflowers, coconut, castor bean, cocoa beans or peanuts); cucumber plants (such as pumpkins, cucumbers and melons); vegetable fibers (such as cotton, linen, hemp or jute); citrus fruits (such as oranges, lemons, grapefruits or tangerines); vegetables (such as spinach, lettuce, cabbage, carrots, tomatoes, potatoes, turmeric or paprika); lauraceae (like avocados,

cinnamon or camphor); tobacco; nuts; coffee; tea; grapevines; hop; durian; bananas; natural rubber; and ornamental (such as flowers, shrubs, broad-leaved or evergreen trees or, for example, conifers).

[0335] In an embodiment, the plants are monocotyledonous plants, more preferably, cereals, in particular wheat or barley. In a specific incorporation, the cereal is wheat. In another specific embodiment, the cereal is triticale. In another embodiment, the cereal is rye. In another embodiment, the cereal is oats. In another embodiment, the cultivated plant is rice. In yet another incorporation, the cultivated plant is sugar cane. In yet another incorporation, the cultivated plant is corn.

[0336] In some incorporations, sugar cane is the first stem of cut sugar cane.

[0337] In some incorporations, sugarcane is a new crop of sugarcane that grows from the stubble of the harvest already harvested.

[0338] In other incorporations, the cultivated plants are dicots. In an embodiment, the cultivated plants are oilseed rape plants.

[0339] In some incorporations, fluensulfone is applied in an amount of about 1 g / ha to about 1000 g / ha. In some embodiments, fluensulfone is applied in an amount of about 100 g / ha to about 700 g / ha. In some embodiments, fluensulfone is applied in an amount of about 100 g / ha to about 200 g / ha. In some embodiments, fluensulfone is applied in an amount of about 300 g / ha to about 400 g / ha. In some embodiments, fluensulfone is applied in an amount of about 600 g / ha to about 700 g / ha. In some embodiments, fluensulfone is applied in an amount of about 160 g / ha. In some embodiments, fluensulfone is applied in an amount of about 320 g / ha. In some embodiments, fluensulfone is applied in an amount of about 640 g / ha.

[0340] In some incorporations, fipronil is applied in an amount of about 1 g / ha to about 500 g / ha. In some embodiments, fipronil is applied in an amount of about 50 g / ha to about 80 g / ha. In some incorporations, fipronil is applied in an amount of about 100 g / ha to about 150 g / ha. In some incorporations, fipronil is applied in an amount of about 225 g / ha to about 275 g / ha. In some incorporations, fipronil is applied in an amount of about 64 g / ha. In some incorporations, fipronil is applied in an amount of about 128 g / ha. In some incorporations, fipronil is applied in an amount of about 256 g / ha.

[0341] In some incorporations, azoxystrobin is applied in an amount of about 1 g / ha to about 100 g / ha. In some embodiments, azoxystrobin is applied in an amount of about 10 g / ha to about 80 g / ha. In some embodiments, azoxystrobin is applied in an amount of about 15 g / ha to about 25 g / ha. In some embodiments, azoxystrobin is applied in an amount of about 35 g / ha to about 45 g / ha. In some embodiments, azoxystrobin is applied in an amount of about 70 g / ha to about 80 g / ha. In some embodiments, azoxystrobin is applied in an amount of about 19 g / ha. In some embodiments, azoxystrobin is applied in an amount of about 38 g / ha. In some embodiments, azoxystrobin is applied in an amount of about 76 g / ha.

[0342] The rate of application of the present composition may vary within wide limits and depend on the nature of the soil, the method of application, the prevailing climatic conditions and other factors governed by the method of application and the time of application. In an embodiment, the composition is generally applied at a rate of about 2 to about 5 L / ha. In a preferred embodiment, the composition is generally applied at a rate of about 2.5 to about 4 L / ha. In a preferred embodiment, the composition is generally applied at a rate of about 3 to about 4 L / ha. In a specific embodiment, the composition is generally applied at a rate of about 2.5 L / ha. In another specific embodiment, the composition is generally applied at a rate of about 4 L / ha. In another specific embodiment, the composition is generally applied at a rate of about 3.5 L / ha. In another specific embodiment, the composition is generally applied at a rate of about 3 L / ha.

[0343] In some incorporations, the composition is applied at a rate of about 1.6 to 3.0 L / ha.

[0344] In some incorporations, the volume of mixture for sugar cane is 200 L / ha.

[0345] In some incorporations, the compositions and / or mixtures disclosed here are applied before planting.

[0346] In some incorporations, the compositions and / or mixtures disclosed here are applied at the time of planting.

[0347] In some incorporations, the compositions and / or mixtures disclosed here are applied as a soil application.

[0348] In some incorporations, application of soil refers to the application of furrow.

[0349] In some incorporations, the application is by spraying on the soil.

[0350] In some incorporations, sugar cane is a first-sprouting cane sugar stem and the composition or mixture disclosed here is applied to the planting furrow with soil equipment.

[0351] In some incorporations, sugarcane is a new crop of sugarcane that grows from the stubble of the harvest already harvested and the composition or mixture disclosed here is applied to the planting line using a tractor sprayer.

[0352] In some embodiments, the composition or mixture disclosed herein is applied with a drop size of 150 to 300 µ VMD.

[0353] In some embodiments, the composition or mixture disclosed here is applied with a drop density greater than or equal to 40 drops / cm2.

[0354] In some embodiments, the composition or mixture disclosed here is applied at a temperature of up to 30 ° C.

[0355] In some incorporations, the composition or mixture disclosed here is applied when the relative humidity of the air is greater than or equal to 50%.

[0356] In some incorporations, the composition or mixture disclosed here is applied when the wind speed is between 3 and 10 km / h.

[0357] In some embodiments, the method comprises diluting any of the mixtures or compositions described here before application. In some embodiments, the mixture or composition is diluted with water. In some embodiments, the mixture or composition is diluted with an agriculturally acceptable carrier. In some embodiments, the mixture or composition is diluted with an agriculturally acceptable carrier other than water.

[0358] In some embodiments, the method comprises applying any of the mixtures or compositions described here with one or more additional active ingredients. In some embodiments, the method comprises applying any of the mixtures or compositions described herein with one or more additional non-active ingredients.

[0359] The present invention provides for the use of any of the mixtures or compositions disclosed herein to control nematodes, improve plant development, regulate plant growth, prevent plant and / or soil disease, and / or control plant disease and / or soil.

[0360] In some incorporations, the use includes applying any of the mixtures or compositions disclosed here on the plant, on the site of the plant or material of propagation of the plant.

[0361] The present invention provides the use of (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin to control nematodes, improve plant development, regulate plant growth plant, prevent plant and / or soil disease, and / or control plant and / or soil disease.

[0362] In some incorporations, the use includes applying fluensulfone, fipronil and azoxystrobin to the plant, at the site of the plant or plant propagation material.

Preparation of the composition described here

[0363] The invention provides a process for preparing the stable composition described herein, the process comprising the steps of: (1) grinding a dispersion of fipronil and azoxystrobin in water; (2) dissolving fluensulfone in an organic carrier to obtain a solution; (3) preparing an emulsion from the solution obtained in step (2); and (4) preparing the suspension composition from the dispersion obtained from step (1) and the emulsion from step (3).

[0364] In some incorporations, step (1) is performed in the presence of at least one physically stabilizing additive. In some embodiments, the physically stabilizing additive is polyvinylpyrrolidone.

[0365] In some embodiments, the organic carrier used in step (2) is derived from N, N-dimethyl amide of fatty acid.

[0366] The invention provides a method for preparing the broad, stable composition described herein, said method comprising the steps of: (1) grinding a dispersion of fipronil and azoxystrobin in water in the presence of polyvinylpyrrolidone; (2) dissolving fluensulfone in a fatty acid N, N-dimethyl amide derivative to obtain a solution; (3) preparing an emulsion from the solution obtained in step (2); and (4) preparing the suspension composition from the dispersion obtained from step (1) and the emulsion from step (3).

[0367] In some incorporations, the block copolymer of poly (alkylene oxide) is added in step (1).

[0368] In some incorporations, the block copolymer of poly (alkylene oxide) is added in step (3).

[0369] In some incorporations, the block copolymer of poly (alkylene oxide) is added in steps (1) and (3).

[0370] In some incorporations, each of the steps described may also include additional additives.

[0371] In some embodiments, the N, N-dialkyl derivative of fatty acid amide is Genagen® 4296. Genagen® 4296 is a dimethylamide based on fatty acids derived naturally from Clariant. In some embodiments, the N, N-dialkyl derivative of fatty acid amide is N, N-dimethyl-decanamide.

[0372] Each merger disclosed herein is considered to be capable of being applicable in each of the other mergers. Thus, all combinations of the various elements described herein are within the scope of the invention. In addition, the elements mentioned in the composition incorporations can be used in the mixture (including synergistic mixture), method, use and process incorporations described here and vice versa.

[0373] The following examples illustrate the practice of the present invention in some of its embodiments, but should not be construed as limiting the scope of the present invention. Further incorporations will become apparent to a person skilled in the art from consideration of the specification and examples. It is intended that the specification, including the examples, be considered exemplary only, without limiting the scope and spirit of the present invention. Experimental section and results

[0374] Formulating a stable composition comprising fluensulfone, fipronil and azoxystrobin is particularly challenging because fluensulfone has limited solubility in organic carrier, and fipronil and azoxystrobin must be suspended in the aqueous carrier.

[0375] In general, unstable suspoemulsion was found to be associated with partial solubility of fipronil in the organic carrier, which leads to crystallization. The combination of polyvinylpyrrolidone and poly (alkylene oxide) block copolymer provided a stable composition.

[0376] Attempts to formulate physically stable compositions comprising fluensulfone, fipronil and azoxystrobin in a liquid composition have failed numerous times. Example 1: Ready-mix composition

Table 1: SE composition of Fluensulfone 160 Fipronil 64 Azoxystrobin 19 Raw material CAS name% Commercial quantity weight / per 1000 weight liters (±) -5-amino-1- (2,6- dichloro- α, α, α- 64 kg (100%) trifluoro-p-tolyl) - Fipronil 120068- 6.04% (65 kg for 4-trifluoro-methyl - 37-3 98%) sulfinyl-pyrazole-3-carbonitrile (E) -2- { 2- [cyano-phenoxy-pyrimidin-4-Azoxystrobin 131860- 1.86% 19 kg (100%) iloxy] phenyl} -3- 33-8 (20 kg for 97.5% methoxy acrylate) methyl 5- chlorine-2- (3,4,4-trifluor-but-3-enyl-fluensulfone 318290- 15.24 160 kg sulfonyl) -1.3- 98-1% (100%) (164 thiazole kg to 97.5 %) Homopolymer of 1- PVK K-30 9003- 1.39% 15 kg ethenyl-2- 39-8 pyrrolidinone Polymer in Synperonic 9003- 2.79% 30 kg EO-PO-PE / F 68 11-6 triblocks

EO Dioctil- LANKROPOL KO2 577-11- 0.46% 5 kg GERONPOCYA sulfosuccinate 75 7 sodium Non-SILICAID aqueous emulsion 52-30 Ionic patent 0.56% 6 kg polydimethylsiloxanes SILCOLAPSE ada 432 Butyl-hydroxy-IONOL CP 128- 37- 0.19% 2 kg toluene 0 Soybean oil EPOXOL D65 8013- 0.19% 32 kg epoxidated AGNIQUE ESO 07-8 81-GN, N-dimethyl- Genagen 4296 14433- 14.40 155 kg decanamide Rhdiasolv 76- 2% ADMA 10 ATLAS G-5002L block copolymer Patent 2.79% 30 kg butylate

Xanthan gum AG RH 23 11138- 0.15% 1.6 kg 66-2 (benzyloxy) methanol> 9 PREVENTOL D2 14548- 0.01% 0.16 kg 8% 60-8 1,2-benzisothiazolin- Proxel GXL 2634 - 0.01 0.16 kg 3-one / 33- kg sodium hydroxide 5 / 1310- 73-2 Fresh water Fresh water ~ 53.9 Up to 3% 1000 L (~ 580.5 kg) Specification: Appearance - Ivory-white liquid Fluensulfone concentration - 150.4-169.6 g / L Fipronil concentration - 57.6-70.4 g / L Azoxystrobin concentration - 16.2-21.8 g / L Density - 1.06-1.1 g / mL pH after production - 5-6.5 pH of the final formulation - 3.5-6.0 Particle size - d90 <7 pm, microscope inspection Persistent foam (1.5% ) - <60 mL Viscosity (S62, 12 rpm, 25 ° C) - 1100-2300 cP Type of packaging: AMRAZ: COEX (HDPE / EVOH) - suitable PACHMAS: COEX (PE / PA) - appropriate Preparation procedure Step 1 : preparation of the suspension composition

[0377] Fresh water was loaded into the container. PVP K-30, SYNPERONIC PE / L 68, LANKROPONOL K02 and half of SILCOLAPSE 432 were added and mixed until a homogeneous solution was obtained and the materials were completely dissolved. Fipronil and azoxystrobin were added gradually during mixing. A high shear homogenizer was used to obtain a homogeneous mixture. The dispersion was ground in a glass microsphere mill until a particle size distribution of d90 <3.5 µm was achieved. The 2% AGRH 23 solution was added to the mixture during mixing to prepare the suspension composition. Step 2: Preparation of the organic carrier

[0378] Fluensulfone was heated until it melted completely. Genagen® 4296 was loaded into the container. Fluensulfone was added to the vessel during mixing and heating to 40 ° C. The solution was filtered (5 µm filter) to achieve a clear solution. IONOL and EPOXOL were added and mixed until a homogeneous solution was obtained to prepare the organic carrier solution. Step 3: preparing an emulsion from Step 2

[0379] Water was loaded into the container. Atlas G-5002L, SYNPERONIC ™ PE / L 68, LANKROPOL KO2 and SILCOLAPSE 432 were added and mixed until a homogeneous solution was obtained and the materials were completely dissolved. The organic carrier solution from Step 2 was heated to a temperature of 45-50 ° C. During high shear application the heated organic carrier solution from Step 2 was added using a gentle stream in three different portions. Shearing was applied until droplet size distribution of d90 <1 pm was achieved to prepare the emulsion. Step 4: preparation and suspoemulsion

[0380] The emulsion from Step 3 was loaded into the reactor. The suspension from Step 1 was added using slow pouring and light agitation. 2% AGRH 23 and water were added to achieve a viscosity of up to 2200 cP (spindle 62 at 12 rpm) to prepare the suspoemulsion.

[0381] The stability test results of this Fluensulfone 160 Fipronil 64 Azoxystrobin 19 Composition SE are shown in Table 2 below.

Table 2: Stability of SE Composition of Fluensulfone 160 Fipronil 64 Azoxystrobin 19 Before After 2 Tempera- After 2 Limits from weeks to ture weeks to normal storage- 4 ° C ambient 54 ° C namento Homogeneous formulation Sus- Formulation formulation homogeneous ivory Homogeneous appearance- small color of genea nea color ivory white yellow ivory on top Concentration of 150.4- 159.8 158.25 154.8 159.7 MCW-2 (g / L) 169, 6 (14.8%) (14.7%) (14.4%) (14.8%) Concentration of 57.6- (5.9%) 62.35 61.25 62.58 (5.8 %) Fipronil (g / L) 70.4 63.7 (5.8%) (5.7%) 16.15- (1.8%) concentration 19.35 18.27 azoxystrobin 19.42 (1 , 8%) 21.85 19.44 (1.8%) (1.7%) (g / L) Density (g / mL) 1.08 1.075 1.075 1.079 pH 5.18 5.29 4.02 5 , 21 Viscosity, cP 1750 1660 1300 1690 (sp.62, 12 rpm) Max. 5% - 2.91 residue Max. Not flow 0.25% material - enough - 0.15 residue rinses Size d90 <7 In specifications (microscope) particles, µm µm Persistent foam 40/4 30/0 3 0/0 20/0 (1.5%) Suspensibility 99.87 98.93% 99.15% 98.26% MCW-2 Suspensibility 99.83 98.87% 99.24% 98.10% fipronil Suspensibility 104.12 97.15% 99.22% 96.13% azoxystrobin

2% in WSR (10%, 75µm) 0.35% 0.408% 0.04% 0.236% maximum Stability of Ok Ok Ok Ok emulsion (1.5%) Test of effectiveness of the mixture and composition in sugar cane

[0382] Experiments were performed to determine the effectiveness of the composition comprising fluensulfone, fipronil and azoxystrobin to (I) control nematodes, (II) increase the vigor of the plant culture and (III) increase the root mass. Materials:

[0383] Fluensulfone, (EC) emulsifiable concentrate, I.a. Concentration: 480.0000 g / L of commercial product (LEGACY).

[0384] Azoxystrobin, (SC) concentrated suspension, I.a. Concentration: 250.0000 g / L of commercial product (MIRADOR 250 SC).

[0385] Fipronil, (WG) dispersible granules, I.a. Concentration: 800.0000 g / L of commercial product (ALBATROSS 800 WG).

[0386] Artificial soil infestation was obtained with Meloidogyne javanica inoculants in IAPAR, with J2 nematodes and eggs (20,000 J2 and eggs per plot). Method:

[0387] The three active ingredients (fluensulfone, fipronil and azoxystrobin) were tested in sugarcane culture to control Meloidogyne javanica.

[0388] A MIL FI 0437/09 tank mixture (fluensulfone 480 g a.i./ha EC); MIL FI 0304/05 (fipronil 800 g ai / ha WG) and MIL FF 0357/05 (azoxystrobin 250 g ai / ha SC) and the ready-mix composition (Example 1, ADA FI 0017) (fluensulfone 160 + fipronil 64 + azoxystrobin 19.7 g ai / ha SE) were applied (1-2 days after artificial soil infestation with Meloidogyne javanica) to the sugarcane culture to control Meloidogyne javanica.

[0389] Sugarcane was planted at the time of application in the planting furrow. The composition of ready mix or tank mix was applied during the planting of the harvest in a jet directed on the planting furrow, close to the sugar cane sticks.

[0390] 4 replicates of each trial were performed.

[0391] The experimental unit consisted of plots of land 0.2 m wide and 0.75 m long (0.15 m2) (considering the useful area of the central plot of 0.15 m2 for the evaluations). The composition of the ready mix from Example 1 and the tank mix were sprayed once in the planting groove (200.00 L / ha), simulating a 50 cm application range, before planting, when the sugarcane was in stage 0 (zero) of the general BBCH scale.

[0392] Application equipment: pressurized coastal to CO2 with a Teejet A11004VS tip bar.

[0393] Agronomic information: Early variety with high agro-industrial productivity. Without tipper converter. It has resistance to charcoal, bleaching, rust, false red stripes and mosaic; and medium resistance to red streaks, nematodes and the borer-rot complex.

[0394] Fifty (50) days after application (DAT), the number of nematodes per 5 g of roots was counted.

[0395] The studies were carried out according to IN 36/42, including the sending of the MAPA spreadsheet (until the day of each month) to the federation unit.

[0396] Evaluated parameters: Nematodes and eggs in the soil (0 and 50 DAT days after treatment), nematodes and eggs in the roots

(50 DAT), use at least 5 g of root and report in the results the count of the number of J2 + eggs per 5 g of roots.

[0397] In addition, the reproduction factor (FR) was calculated. Plant emergence and plant biometry (50 DAT).

[0398] Tables 3-6 below show the results for the control of nematodes for tank mixing of three active ingredients compared to the ready mix composition comprising the same three active ingredients.

Table 3 Number of eggs + applied treatment Dose nematodes (J2) in 5 g of root 50 DAT2 3/14/19 Inoculated control - 18403 b4 Fluensulfone 480 1333.3 mL / ha Fipronil 800 320 g / ha 321.25 c Azoxystrobin 250 304 mL / ha Fluensulfone 480 666.6 mL / ha Fipronil 800 160 g / ha 502.5 c Azoxystrobin 250 152 mL / ha Fluensulfone 480 333.3 mL / ha Fipronil 800 80 g / ha 1060 c Azoxystrobin 250 76 mL / ha Fluensulfone 160 Fipronil 64 4000 mL / ha 117.5 c Azoxystrobin 19 Fluensulfone 160 Fipronil 64 2000 mL / ha 285 c Azoxystrobin 19 Fluensulfone 160 Fipronil 64 1000 mL / ha 570 c Azoxystrobin 19 CV% 53.58

Table 4 Vigor Treatment applied Dose 3/14/19 Inoculated control - 100 f Fluensulfone 480 1333.3 mL / ha Fipronil 800 320 g / ha 120 c Azoxystrobin 250 304 mL / ha Fluensulfone 480 666.6 mL / ha Fipronil 800 160 g / ha 111.25 c Azoxystrobin 250 152 mL / ha Fluensulfone 480 333.3 mL / ha Fipronil 800 80 g / ha 114.5 a Azoxystrobin 250 76 mL / ha Fluensulfone 160 Fipronil 64 4000 mL / ha 136.25 a Azoxystrobin 19 Fluensulfone 160 Fipronil 64 2000 mL / ha 130 b Azoxystrobin 19 Fluensulfone 160 Fipronil 64 1000 mL / ha 120 c Azoxystrobin 19 CV% - 3.53 Table 5 Biomass Treatment applied Dose 3/14/19 Inoculated control - 3.67ns Fluensulfone 480 1333 , 3 mL / ha Fipronil 800 320 g / ha 4.42 Azoxystrobin 250 304 mL / ha Fluensulfone 480 666.6 mL / ha Fipronil 800 160 g / ha 4.23 Azoxystrobin 250 152 mL / ha Fluensulfone 480 333.3 mL / ha Fipronil 800 80 g / ha 4.27 Azoxystrobin 250 76 mL / ha Fluensulfone 160 Fipronil 64 4000 mL / ha 4.94 Azoxystrobin 19 Fluensulfone 160 Fipronil 64 2000 mL / ha 4.67 Azoxystrobin 19 Fl uensulfone 160 Fipronil 64 1000 mL / ha 4.51 Azoxystrobin 19

[0399] The effectiveness of the composition of Example 1 (ready mix) and tank mixes for controlling nematodes, increasing harvest vigor and increasing root mass are shown in Table 6 below.

Table 7 shows the statistical analysis of variance for the results.

Table 6 Rate Method * Repeat Biomass Count Application rate of root nematode vigor (g) relative Tank mix High A 460 4.6 125 Tank mix High B 280 4.7 115 Tank mix High C 225 3.9 122 Tank mix High D 320 4.4 118 Tank mix Medium A 950 4.1 112 Tank mix Medium B 560 3.9 108 Tank mix Medium C 320 5.0 110 Tank mix Medium D 180 4.0 115 Low tank mix A 2050 4.5 118 Low tank mix B 465 3.8 120 Low tank mix C 1025 4.9 110 Low tank mix D 700 3.9 110 High ready mix A 80 4.5 140 Ready mix High B 150 4.9 138 Ready mix High C 180 5.1 132 Ready mix High D 60 5.3 135 Ready mix Medium A 80 4.9 135 Ready mix Medium B 90 4.2 125 Ready mix Medium C 120 4.3 132 Ready mix Medium D 130 4.8 128 Ready mix Low A 190 4.8 110 Ready mix Low B 700 4.8 130 Ready mix Low C 500 4.8 125 Ready mix Low D 890 3.7 115 * Fluensulfone / fipr onil / azoxystrobin g / ha Alta - 640/256/76; Average - 320/128/38; Low - 160/64/19

Table 7: Statistical analysis of variance Statistical analysis of variance Count Value Biomass Value Index P value of roots P of vigor P nematodes (g) relative Mixture 627.19 4.305 115.25 of tank 0.017 0.046 <0.001 Mixture 264.167 7.705 128.75 ready Results

[0400] Contributing to the analysis of the agronomic efficiency and viability of the composition of the ready mix of Example 1 (fluensulfone 160 + fipronil 64 + azoxystrobin 19.7 g a.i./ha SE), nematode vigor and culture evaluations were carried out. Analyzing the data in Table 6, we observed a significant decrease in nematode count, a significant increase in root biomass and a significant increase in the relative vigor index in plants treated with the ready mix composition compared to the tank mix of the same three active ingredients when applied at the same rates.

Claims (31)

1. Stable broad-spectrum composition, characterized by the fact that it comprises: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin. 2. Composition, according to claim 1, characterized by the fact that it is a suspoemulsion. Composition according to either of Claims 1 and 2, characterized in that it comprises an aqueous carrier and an organic carrier, where azoxystrobin and fipronil are suspended in the aqueous carrier and fluensulfone is dissolved in the organic carrier. 4. Composition according to claim 3, characterized in that the organic carrier is N, N-dimethyl-decanamide. Composition according to any one of claims 1 to 4, characterized by the fact that it comprises at least one physically stabilizing system. 6. Composition according to claim 5, characterized in that the physically stabilizing system is a combination of polyvinylpyrrolidone and poly (alkylene oxide) block copolymer. Composition according to claim 5, characterized in that the total amount of the physically stabilizing system in the composition varies from about 2% to about 10% by weight based on the total weight of the composition. 8. Composition according to any one of claims 5 to 7, characterized in that the total amount of the physically stabilizing system in the composition is about 4.2% by weight based on the total weight of the composition. Composition according to claim 5, characterized in that the amount of poly (alkylene oxide) block copolymer in the composition is about 2.8% by weight based on the total weight of the composition. 10. Composition according to claim 5, characterized in that the amount of polyvinylpyrrolidone in the composition is about 1.4% by weight based on the total weight of the composition. 11. Composition according to any one of claims 1 to 10, characterized in that the weight ratio between fluensulfone to fipronil to azoxystrobin is 8.5: 3.4: 1. Composition according to any one of claims 1 to 11, characterized in that fluensulfone is in an amount ranging from about 1-60% by weight based on the total weight of the composition. 13. Composition according to claim 12, characterized in that fluensulfone is in an amount of about 15% by weight based on the total weight of the composition. Composition according to any one of claims 1 to 11, characterized in that fipronil is in an amount ranging from about 1-15% by weight based on the total weight of the composition. 15. Composition according to claim 14, characterized in that fipronil is in an amount of about 6% by weight based on the total weight of the composition. 16. Composition according to any one of claims 1 to 11, characterized in that azoxystrobin is in an amount ranging from about 0.1-5% by weight based on the total weight of the composition. 17. Composition according to claim 16, characterized in that azoxystrobin is in an amount of about 1.8% by weight based on the total weight of the composition. 18. Mixture, characterized by the fact that it comprises: (I) an effective amount of fluensulfone, (II) an effective amount of fipronil and (III) an effective amount of azoxystrobin. 19. Mixture according to claim 18, characterized by the fact that it comprises: (I) 160 g / L of fluensulfone, (II) 64 g / L of fipronil and (III) 19 g / L of azoxystrobin. 20. Mixture according to either of claims 18 or 19, characterized in that it is an agricultural mixture or a pesticidal mixture. 21. Mixture according to any one of claims 18 to 20, characterized by the fact that it is for use in sugarcane. 22. Mixture according to any of claims 18 to 21, characterized in that the weight ratio between fluensulfone to fipronil to azoxystrobin is 8.5: 3.4: 1. 23. Method for increasing plant development, characterized in that it comprises applying to the plant, plant site and / or plant propagating material an effective amount of the composition, as defined in any one of claims 1 to 17 or the mixture as defined in any of claims 18 to 22 in order to improve the development of the plant. 24. Method according to claim 23, characterized by the fact that: (a) improving root development; (b) improving the plant's root system; (c) improving the quality of the plant; (d) improving the vigor of the plant; (e) improving the yield of the plant; (f) avoid damage to the root; and / or (g) improve rooting. 25. Method for controlling nematodes, characterized in that it comprises applying to the plant, plant site and / or plant propagating material an effective amount of the composition as defined by any one of claims 1-17 or of the mixture as defined by any one of claims 18 to 22 in order to control nematodes. 26. Method for regulating plant growth, characterized in that it comprises applying to the plant, plant location and / or plant propagating material an effective amount of the composition as defined in any one of claims 1 to 17 or of the mixture as defined in any of claims 18 to 22 in order to regulate the growth of the plant. 27. Method according to any one of claims 23 to 26, characterized in that the one or more plants are monocotyledonous plants. 28. Method, according to any of the claims of 23 to 27, characterized by the fact that one or more plants are sugar cane. 29. Method according to any one of claims 23 to 28, characterized in that an effective amount of the composition is applied at a rate of 3 to 4 L / ha. 30. Method according to any of claims 23 to 29, characterized in that: (a) fluensulfone is applied in an amount of about 1 g / ha to about 1000 g / ha; (b) fipronil is applied in an amount of about 1 g / ha to about 500 g / ha; and / or (c) the azoxystrobin is applied in an amount of about 1 g / ha to about 100 g / ha. 31. Method for preparing the stable broad-spectrum composition, characterized by the fact that it comprises the steps of: (1) grinding a dispersion of fipronil and azoxystrobin in water in the presence of polyvinylpyrrolidone; (2) dissolving fluensulfone in a fatty acid N, N-dimethyl amide derivative to obtain a solution; (3) preparing an emulsion from the solution obtained in step (2); and (4) preparing the suspension composition from the dispersion obtained from step (1) and the emulsion from step (3).