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BR112012023441A2 - emulsificação por fusão - Google Patents

emulsificação por fusão

Info

Publication number
BR112012023441A2
BR112012023441A2 BR112012023441A BR112012023441A BR112012023441A2 BR 112012023441 A2 BR112012023441 A2 BR 112012023441A2 BR 112012023441 A BR112012023441 A BR 112012023441A BR 112012023441 A BR112012023441 A BR 112012023441A BR 112012023441 A2 BR112012023441 A2 BR 112012023441A2
Authority
BR
Brazil
Prior art keywords
particles
phase
colloidal
outer phase
particle
Prior art date
Application number
BR112012023441A
Other languages
English (en)
Inventor
Bingjie Sun
Christian Holtze
David A Weitz
Ho Cheung Shum
Original Assignee
Basf Se
President And Fellows Of Havard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se, President And Fellows Of Havard College filed Critical Basf Se
Publication of BR112012023441A2 publication Critical patent/BR112012023441A2/pt

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/0086—Preparation of sols by physical processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B01F33/301—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions
    • B01F33/3011—Micromixers using specific means for arranging the streams to be mixed, e.g. channel geometries or dispositions using a sheathing stream of a fluid surrounding a central stream of a different fluid, e.g. for reducing the cross-section of the central stream or to produce droplets from the central stream
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0001—Post-treatment of organic pigments or dyes
    • C09B67/0004—Coated particulate pigments or dyes
    • C09B67/0008—Coated particulate pigments or dyes with organic coatings
    • C09B67/0009—Coated particulate pigments or dyes with organic coatings containing organic acid derivatives
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B67/00—Influencing the physical, e.g. the dyeing or printing properties of dyestuffs without chemical reactions, e.g. by treating with solvents grinding or grinding assistants, coating of pigments or dyes; Process features in the making of dyestuff preparations; Dyestuff preparations of a special physical nature, e.g. tablets, films
    • C09B67/0097—Dye preparations of special physical nature; Tablets, films, extrusion, microcapsules, sheets, pads, bags with dyes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F2025/91—Direction of flow or arrangement of feed and discharge openings
    • B01F2025/918—Counter current flow, i.e. flows moving in opposite direction and colliding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1404—Handling flow, e.g. hydrodynamic focusing
    • G01N2015/1413—Hydrodynamic focussing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Colloid Chemistry (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

emulsificação por fusão. a presente invenção refere-se de modo geral a sistemas coloidais, que podem incluir partículas coloidais e/ou outros tipos de partículas. um aspecto da invenção está direcionada geralmente a um sistema que compreende gotículas fluídicas que podem ser pelo menos parcialmente solidificadas, por exemplo, para formar partículas coloidais. em algumas modalidades, são formadas partículas que compreendem pelo menos uma fase externa parcialmente sólida que encapsula uma fase interna. a fase interna pode ser qualquer fase, por exemplo, um sólido, um líquido ou um gás. em alguns casos, solidificar pelo menos uma porção da fase externa das gotículas para formar partículas pode aumentar a estabilidade das partículas e/ou do sistema coloidal que contém as partículas. em um grupo de modalidades, fundir ou liquefazer a fase externa das partículas (por exemplo, pelo aquecimento da partícula a uma temperatura acima da temperatura limiar) pode permitir a liberação de um agente contido dentro da fase interna e/ou permitir que a fase interna aglutine com a fase externa das partículas. a temperatura de fusão da fase externa pode ser controlada em algumas modalidades tal que a fase externa fundirá acima de uma temperatura predeterminada. em algumas modalidades, as partículas podem ser formadas para serem essencialmente livre de um agente estabilizador auxiliar. em algumas modalidades, um agente pode ser encapsulado dentro de uma partícula com eficiência relativamente alta. outros aspectos da invenção são direcionados de modo geral para métodos de fazer e usar tais sistemas coloidais, por exemplo, contendo tais partículas, kits que envolvem tais sistemas coloidais ousimilaressimilares.
BR112012023441A 2010-03-17 2011-03-17 emulsificação por fusão BR112012023441A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31484110P 2010-03-17 2010-03-17
PCT/US2011/028754 WO2011116154A2 (en) 2010-03-17 2011-03-17 Melt emulsification

Publications (1)

Publication Number Publication Date
BR112012023441A2 true BR112012023441A2 (pt) 2016-05-24

Family

ID=44483718

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012023441A BR112012023441A2 (pt) 2010-03-17 2011-03-17 emulsificação por fusão

Country Status (8)

Country Link
US (1) US20110229545A1 (pt)
EP (1) EP2547436A2 (pt)
JP (1) JP2013525087A (pt)
KR (1) KR20130016284A (pt)
CN (1) CN102971069A (pt)
AR (1) AR080405A1 (pt)
BR (1) BR112012023441A2 (pt)
WO (1) WO2011116154A2 (pt)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9039273B2 (en) * 2005-03-04 2015-05-26 President And Fellows Of Harvard College Method and apparatus for forming multiple emulsions
WO2010033200A2 (en) 2008-09-19 2010-03-25 President And Fellows Of Harvard College Creation of libraries of droplets and related species
GB2471522B (en) * 2009-07-03 2014-01-08 Cambridge Entpr Ltd Microfluidic devices
EP2544806B1 (en) * 2009-08-28 2014-12-03 Georgia Tech Research Corporation Method and electro-fluidic device to produce emulsions and particle suspensions
EP2473263B1 (en) 2009-09-02 2022-11-02 President and Fellows of Harvard College Multiple emulsions created using jetting and other techniques
KR20140034242A (ko) 2011-05-23 2014-03-19 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 다중 에멀젼을 포함하는 에멀젼의 제어
EP3120923A3 (en) 2011-07-06 2017-03-01 President and Fellows of Harvard College Article comprising a particle having a shell and a fluid
EP2760578B1 (en) * 2011-09-28 2020-08-26 President and Fellows of Harvard College Systems and methods for droplet production and/or fluidic manipulation
BR112014019323A8 (pt) 2012-02-08 2017-07-11 Harvard College Formação de gotícula com uso de decomposição de fluido
US9597648B2 (en) 2012-10-17 2017-03-21 The Procter & Gamble Company Non-spherical droplet
US20160279068A1 (en) 2013-11-08 2016-09-29 President And Fellows Of Harvard College Microparticles, methods for their preparation and use
WO2015160919A1 (en) 2014-04-16 2015-10-22 President And Fellows Of Harvard College Systems and methods for producing droplet emulsions with relatively thin shells
EP3224419A4 (en) * 2014-11-24 2018-06-27 President and Fellows of Harvard College Multiple emulsions comprising rigidified portions
WO2016085743A1 (en) 2014-11-24 2016-06-02 President And Fellows Of Harvard College Methods and systems for encapsulation of actives within droplets and other compartments
EP3362032A4 (en) 2015-10-13 2019-05-01 President and Fellows of Harvard College SYSTEMS AND METHODS OF MAKING AND USING GEL MICROSPHERES
CN105833813B (zh) * 2016-03-24 2018-04-10 北京科技大学 室温液滴微反应器和制备二氧化锆凝胶微球的方法
CN106492716B (zh) * 2016-12-20 2024-01-30 中国工程物理研究院激光聚变研究中心 一体式双重乳粒发生装置及其加工方法
WO2018115978A2 (en) * 2016-12-23 2018-06-28 University Of Limerick Water-in-oil-in water emulsions for analysis of biological and chemical samples
FR3064191B1 (fr) * 2017-03-21 2019-04-26 Calyxia Procede de preparation de capsules comprenant au moins une substance hydrosoluble ou hydrophile et capsules obtenues
EP3604215A4 (en) * 2017-03-28 2020-02-26 Fujifilm Corporation GROUP (III) - (V) SEMICONDUCTOR NANOPARTICLE PRODUCTION METHOD, GROUP (III) - (V) SEMICONDUCTOR QUANTIC POINT PRODUCTION METHOD, AND FLOW REACTION SYSTEM
US10408852B2 (en) * 2017-04-26 2019-09-10 Lawrence Livermore National Security, Llc Automated control of microfluidic devices based on machine learning
WO2019213075A1 (en) * 2018-04-30 2019-11-07 The Trustees Of Columbia University In The City Of New York Methods, systems, and apparatus for encapsulating a sequestration medium
US11673107B2 (en) 2018-05-01 2023-06-13 Hewlett-Packard Development Company, L.P. Sequential encapsulation of reagents
WO2019241138A1 (en) * 2018-06-12 2019-12-19 Sabic Global Technologies, B.V. Compositions, use and methods for tunable tenacity of active(s) encapsulated in colloidosome architectures
KR20200020404A (ko) 2018-08-17 2020-02-26 서울대학교산학협력단 식물 추출물 또는 이로부터 유래되는 화합물을 함유하는 그랜자임 b 억제용 조성물
US10731012B2 (en) * 2018-11-06 2020-08-04 President And Fellows Of Harvard College Anti-clogging microfluidic multichannel device
GB201818936D0 (en) * 2018-11-21 2019-01-02 Univ Loughborough Microfluid device
US11866581B2 (en) 2019-09-09 2024-01-09 Xerox Corporation Particles comprising polyamides with in-backbone optical absorbers and related methods
US11814494B2 (en) 2019-09-09 2023-11-14 Xerox Corporation Thermoplastic polyester particles and methods of production and uses thereof
US11802206B2 (en) 2019-09-09 2023-10-31 Xerox Corporation Particles comprising polyamides with pendent pigments and related methods
US11643566B2 (en) 2019-09-09 2023-05-09 Xerox Corporation Particulate compositions comprising a metal precursor for additive manufacturing and methods associated therewith
US11572441B2 (en) 2019-09-09 2023-02-07 Xerox Corporation Polyamides with pendent pigments and related methods
US11866562B2 (en) 2019-09-09 2024-01-09 Xerox Corporation Nanoparticle-coated elastomeric particulates and methods for production and use thereof
US11866552B2 (en) 2019-09-09 2024-01-09 Xerox Corporation Polyamide particles and methods of production and uses thereof
US11859051B2 (en) 2019-09-09 2024-01-02 Xerox Corporation Polyamides with in-backbone optical absorbers and related methods
US11667788B2 (en) 2019-09-09 2023-06-06 Xerox Corporation Nanoparticle-coated elastomeric particulates and surfactant-promoted methods for production and use thereof
US11787937B2 (en) 2019-09-09 2023-10-17 Xerox Corporation Particles comprising polyamides with pendent optical absorbers and related methods
US11801617B2 (en) * 2019-09-09 2023-10-31 Xerox Corporation Optical absorbing thermoplastic polymer particles and methods of production and uses thereof
US11753505B2 (en) 2019-09-09 2023-09-12 Xerox Corporation Polyamides with pendent optical absorbers and related methods
US11584086B2 (en) * 2019-12-20 2023-02-21 Xerox Corporation Particles comprising marking additives for selective laser sintering-based manufacturing systems
US11787944B2 (en) 2020-11-25 2023-10-17 Xerox Corporation Pigmented polymer particles and methods of production and uses thereof
WO2023152031A1 (en) * 2022-02-08 2023-08-17 Microcaps Ag Capsules with solidified matrix
KR20240105780A (ko) 2022-12-29 2024-07-08 가톨릭대학교 산학협력단 미세유체 장치 및 이를 이용한 미세 입자 제조방법

Family Cites Families (101)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US458398A (en) 1891-08-25 Machine
US2379816A (en) * 1939-07-17 1945-07-03 Gelatin Products Corp Capsulating process and apparatus
US2422804A (en) 1946-01-26 1947-06-24 Walter H Schroeder Kite
NL6605917A (pt) * 1965-04-30 1966-10-31
US3675901A (en) * 1970-12-09 1972-07-11 Phillips Petroleum Co Method and apparatus for mixing materials
US3816331A (en) * 1972-07-05 1974-06-11 Ncr Continuous encapsulation and device therefor
US4279435A (en) * 1973-04-10 1981-07-21 Perfection Corporation Gas riser apparatus
GB1500276A (en) 1974-06-12 1978-02-08 Smiths Industries Ltd Two-part electrical connectors and electrical interlocks including them
NL180807C (nl) * 1975-12-26 1987-05-04 Morishita Jintan Co Inrichting voor het vervaardigen van naadloze, met materiaal gevulde capsules.
US4279345A (en) * 1979-08-03 1981-07-21 Allred John C High speed particle sorter using a field emission electrode
JPS6057907B2 (ja) * 1981-06-18 1985-12-17 工業技術院長 液体の混合噴霧化方法
US5100933A (en) * 1986-03-31 1992-03-31 Massachusetts Institute Of Technology Collapsible gel compositions
US4732930A (en) * 1985-05-20 1988-03-22 Massachusetts Institute Of Technology Reversible, discontinuous volume changes of ionized isopropylacrylamide cells
US5209978A (en) * 1985-12-26 1993-05-11 Taisho Pharmaceutical Co., Ltd. Seamless soft capsule and production thereof
US5204112A (en) * 1986-06-16 1993-04-20 The Liposome Company, Inc. Induction of asymmetry in vesicles
US4743507A (en) * 1986-09-12 1988-05-10 Franses Elias I Nonspherical microparticles and method therefor
US4978483A (en) * 1987-09-28 1990-12-18 Redding Bruce K Apparatus and method for making microcapsules
US5418154A (en) * 1987-11-17 1995-05-23 Brown University Research Foundation Method of preparing elongated seamless capsules containing biological material
US4931225A (en) * 1987-12-30 1990-06-05 Union Carbide Industrial Gases Technology Corporation Method and apparatus for dispersing a gas into a liquid
JPH0694483B2 (ja) * 1988-01-29 1994-11-24 三田工業株式会社 粒径の増大した単分散重合体粒子の製造方法
US5093602A (en) * 1989-11-17 1992-03-03 Charged Injection Corporation Methods and apparatus for dispersing a fluent material utilizing an electron beam
US5326692B1 (en) * 1992-05-13 1996-04-30 Molecular Probes Inc Fluorescent microparticles with controllable enhanced stokes shift
GB9021061D0 (en) * 1990-09-27 1990-11-07 Unilever Plc Encapsulating method and products containing encapsulated material
US5216096A (en) * 1991-09-24 1993-06-01 Japan Synthetic Rubber Co., Ltd. Process for the preparation of cross-linked polymer particles
US5512131A (en) * 1993-10-04 1996-04-30 President And Fellows Of Harvard College Formation of microstamped patterns on surfaces and derivative articles
JP2939155B2 (ja) * 1994-06-13 1999-08-25 プラクスエア・テクノロジー・インコーポレイテッド 燃焼のための噴霧角度の小さい液体燃料噴霧器
US5762775A (en) * 1994-09-21 1998-06-09 Lockheed Martin Energy Systems, Inc. Method for electrically producing dispersions of a nonconductive fluid in a conductive medium
WO1996029629A2 (en) 1995-03-01 1996-09-26 President And Fellows Of Harvard College Microcontact printing on surfaces and derivative articles
US6238690B1 (en) * 1995-03-29 2001-05-29 Warner-Lambert Company Food products containing seamless capsules and methods of making the same
US5888538A (en) * 1995-03-29 1999-03-30 Warner-Lambert Company Methods and apparatus for making seamless capsules
JP3759986B2 (ja) * 1995-12-07 2006-03-29 フロイント産業株式会社 シームレスカプセルおよびその製造方法
US6355198B1 (en) 1996-03-15 2002-03-12 President And Fellows Of Harvard College Method of forming articles including waveguides via capillary micromolding and microtransfer molding
US5942443A (en) * 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
US6386463B1 (en) * 1996-05-13 2002-05-14 Universidad De Sevilla Fuel injection nozzle and method of use
US6405936B1 (en) * 1996-05-13 2002-06-18 Universidad De Sevilla Stabilized capillary microjet and devices and methods for producing same
US6187214B1 (en) * 1996-05-13 2001-02-13 Universidad De Seville Method and device for production of components for microfabrication
US6189803B1 (en) * 1996-05-13 2001-02-20 University Of Seville Fuel injection nozzle and method of use
ES2140998B1 (es) * 1996-05-13 2000-10-16 Univ Sevilla Procedimiento de atomizacion de liquidos.
US6248378B1 (en) * 1998-12-16 2001-06-19 Universidad De Sevilla Enhanced food products
US6196525B1 (en) * 1996-05-13 2001-03-06 Universidad De Sevilla Device and method for fluid aeration via gas forced through a liquid within an orifice of a pressure chamber
US6299145B1 (en) * 1996-05-13 2001-10-09 Universidad De Sevilla Device and method for fluid aeration via gas forced through a liquid within an orifice of a pressure chamber
US6197835B1 (en) * 1996-05-13 2001-03-06 Universidad De Sevilla Device and method for creating spherical particles of uniform size
BR9710054A (pt) * 1996-06-28 2000-01-11 Caliper Techn Corp Aparelhos para separar compostos de teste para um efeito sobre um sistema bioquìmico e para detectar ummefeito de um composto de teste sobre um sistema bioquìmico, processos de determinação de se uma amostra contém um composto capaz de afetar um sistema bioquìmico, de separação de uma pluralidade de compostos de teste para um efeito sobre um sistema bioquìmico e usos de um sistema microfluido e de um substrato de ensaio.
US6221654B1 (en) * 1996-09-25 2001-04-24 California Institute Of Technology Method and apparatus for analysis and sorting of polynucleotides based on size
DE19706658A1 (de) * 1997-02-20 1998-08-27 Mannesmann Vdo Ag Vorrichtung zur Verringerung von Schwallgeräuschen in einem Kraftstoffbehälter
DE19882362T1 (de) * 1997-04-30 2000-05-18 Point Biomedical Corp Mikropartikel, geeignet als Ultraschallkontrastmittel und zum Transport von Arzneimitteln in den Blutstrom
JP4102459B2 (ja) * 1997-05-14 2008-06-18 森下仁丹株式会社 生体高分子を合成するシームレスカプセルおよびその製造方法
DK1801214T3 (da) * 1997-07-07 2011-01-24 Medical Res Council In vitro sorteringsfremgangsmåde
US6540895B1 (en) * 1997-09-23 2003-04-01 California Institute Of Technology Microfabricated cell sorter for chemical and biological materials
AU770678B2 (en) * 1999-05-17 2004-02-26 Caliper Life Sciences, Inc. Focusing of microparticles in microfluidic systems
US6592821B1 (en) * 1999-05-17 2003-07-15 Caliper Technologies Corp. Focusing of microparticles in microfluidic systems
US20030124509A1 (en) * 1999-06-03 2003-07-03 Kenis Paul J.A. Laminar flow patterning and articles made thereby
US6380297B1 (en) * 1999-08-12 2002-04-30 Nexpress Solutions Llc Polymer particles of controlled shape
US6890487B1 (en) * 1999-09-30 2005-05-10 Science & Technology Corporation ©UNM Flow cytometry for high throughput screening
DE19961257C2 (de) * 1999-12-18 2002-12-19 Inst Mikrotechnik Mainz Gmbh Mikrovermischer
WO2001051918A1 (en) * 2000-01-12 2001-07-19 Ut-Battelle, Llc A microfluidic device and method for focusing, segmenting, and dispensing of a fluid stream
CN1189159C (zh) * 2000-05-05 2005-02-16 欧莱雅 含水溶性美容活性组分水性核的微胶囊及含其的组合物
US6645432B1 (en) 2000-05-25 2003-11-11 President & Fellows Of Harvard College Microfluidic systems including three-dimensionally arrayed channel networks
US6777450B1 (en) * 2000-05-26 2004-08-17 Color Access, Inc. Water-thin emulsions with low emulsifier levels
AU2001266215A1 (en) 2000-06-30 2002-01-14 Ariel Industries Plc Controlled flow of displaced material in self-pierce fastening
US6301055B1 (en) * 2000-08-16 2001-10-09 California Institute Of Technology Solid immersion lens structures and methods for producing solid immersion lens structures
US6508988B1 (en) * 2000-10-03 2003-01-21 California Institute Of Technology Combinatorial synthesis system
US6778724B2 (en) * 2000-11-28 2004-08-17 The Regents Of The University Of California Optical switching and sorting of biological samples and microparticles transported in a micro-fluidic device, including integrated bio-chip devices
US20040096515A1 (en) * 2001-12-07 2004-05-20 Bausch Andreas R. Methods and compositions for encapsulating active agents
CA2438856C (en) * 2001-02-23 2007-08-07 Japan Science And Technology Corporation Process and apparatus for producing emulsion and microcapsules
US6752922B2 (en) * 2001-04-06 2004-06-22 Fluidigm Corporation Microfluidic chromatography
US20030015425A1 (en) * 2001-06-20 2003-01-23 Coventor Inc. Microfluidic system including a virtual wall fluid interface port for interfacing fluids with the microfluidic system
JP2006507921A (ja) 2002-06-28 2006-03-09 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 流体分散のための方法および装置
GB2395196B (en) * 2002-11-14 2006-12-27 Univ Cardiff Microfluidic device and methods for construction and application
US7595195B2 (en) * 2003-02-11 2009-09-29 The Regents Of The University Of California Microfluidic devices for controlled viscous shearing and formation of amphiphilic vesicles
US7041481B2 (en) * 2003-03-14 2006-05-09 The Regents Of The University Of California Chemical amplification based on fluid partitioning
US20060078893A1 (en) * 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
AU2004229440B2 (en) 2003-04-10 2010-08-12 President And Fellows Of Harvard College Formation and control of fluidic species
US20050032238A1 (en) * 2003-08-07 2005-02-10 Nanostream, Inc. Vented microfluidic separation devices and methods
EP1658133A1 (en) * 2003-08-27 2006-05-24 President And Fellows Of Harvard College Electronic control of fluidic species
CA2560272C (en) * 2004-03-23 2012-05-08 Japan Science And Technology Agency Method and apparatus for producing microdroplets
US20050221339A1 (en) * 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
JP2006021137A (ja) * 2004-07-08 2006-01-26 Chukyo Yushi Kk Ｗ／ｏ／ｗ型マイクロカプセル
US7759111B2 (en) * 2004-08-27 2010-07-20 The Regents Of The University Of California Cell encapsulation microfluidic device
US7968287B2 (en) * 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
WO2006051552A2 (en) * 2004-11-15 2006-05-18 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Directed evolution and selection using in vitro compartmentalization
US20070054119A1 (en) * 2005-03-04 2007-03-08 Piotr Garstecki Systems and methods of forming particles
US9039273B2 (en) 2005-03-04 2015-05-26 President And Fellows Of Harvard College Method and apparatus for forming multiple emulsions
JP2006349060A (ja) 2005-06-16 2006-12-28 Ntn Corp ボールねじ
US8734003B2 (en) * 2005-09-15 2014-05-27 Alcatel Lucent Micro-chemical mixing
JP2009519975A (ja) * 2005-12-16 2009-05-21 ユニバーシティ・オブ・カンザス 治療薬を送達するナノクラスター
EP2364774A3 (en) * 2006-01-11 2014-06-04 Raindance Technologies, Inc. Microfluidic Devices And Methods Of Use In The Formation And Control Of Nanoreactors
US7537897B2 (en) * 2006-01-23 2009-05-26 Population Genetics Technologies, Ltd. Molecular counting
EP2530168B1 (en) * 2006-05-11 2015-09-16 Raindance Technologies, Inc. Microfluidic Devices
US9029085B2 (en) * 2007-03-07 2015-05-12 President And Fellows Of Harvard College Assays and other reactions involving droplets
US7776927B2 (en) * 2007-03-28 2010-08-17 President And Fellows Of Harvard College Emulsions and techniques for formation
WO2008134153A1 (en) * 2007-04-23 2008-11-06 Advanced Liquid Logic, Inc. Bead-based multiplexed analytical methods and instrumentation
US20090068170A1 (en) * 2007-07-13 2009-03-12 President And Fellows Of Harvard College Droplet-based selection
WO2009048532A2 (en) * 2007-10-05 2009-04-16 President And Fellows Of Harvard College Formation of particles for ultrasound application, drug release, and other uses, and microfluidic methods of preparation
WO2009123348A1 (ja) * 2008-03-31 2009-10-08 日本たばこ産業株式会社 ウイルス濃縮法
EP2303246A1 (en) * 2008-06-05 2011-04-06 President and Fellows of Harvard College Polymersomes, colloidosomes, liposomes, and other species associated with fluidic droplets
JP5054062B2 (ja) * 2009-05-07 2012-10-24 株式会社カネカ 固体脂を使ったマイクロカプセルの製造方法
US8835358B2 (en) * 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
DE112011103680B4 (de) 2010-11-05 2018-05-17 Lg Electronics Inc. Verfahren und Vorrichtungen zum Durchführen einer Übergabe in einem drahtlosen Kommunikationssystem
KR20140034242A (ko) * 2011-05-23 2014-03-19 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 다중 에멀젼을 포함하는 에멀젼의 제어
EP2750787A2 (en) * 2011-08-30 2014-07-09 President and Fellows of Harvard College Systems and methods for shell encapsulation

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JP2013525087A (ja) 2013-06-20
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WO2011116154A2 (en) 2011-09-22
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US20110229545A1 (en) 2011-09-22

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