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BR112012014082A2 - composições e métodos que compreendem variantes de protease - Google Patents

composições e métodos que compreendem variantes de protease

Info

Publication number
BR112012014082A2
BR112012014082A2 BR112012014082A BR112012014082A BR112012014082A2 BR 112012014082 A2 BR112012014082 A2 BR 112012014082A2 BR 112012014082 A BR112012014082 A BR 112012014082A BR 112012014082 A BR112012014082 A BR 112012014082A BR 112012014082 A2 BR112012014082 A2 BR 112012014082A2
Authority
BR
Brazil
Prior art keywords
compositions
methods
protease variants
variants
protease
Prior art date
Application number
BR112012014082A
Other languages
English (en)
Other versions
BR112012014082B1 (pt
Inventor
Pisarchik Alexander
J Poulose Ayrookaran
Torres-Pazmino Daniel
A Estell David
T Kellis James
Roy Basler Joshua
Gustavo Cascao-Pereira Luis
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Publication of BR112012014082A2 publication Critical patent/BR112012014082A2/pt
Publication of BR112012014082B1 publication Critical patent/BR112012014082B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21062Subtilisin (3.4.21.62)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cleaning By Liquid Or Steam (AREA)
  • Accessory Of Washing/Drying Machine, Commercial Washing/Drying Machine, Other Washing/Drying Machine (AREA)
  • Eyeglasses (AREA)

Abstract

''composições e métodos que compreendem variantes de protease''. a presente invenção fornece variantes de protease, e métodos de uso de tais variantes de protease e composições.
BR112012014082-5A 2009-12-09 2010-12-09 variante de protease isolada e seu método de produção, ácido nucleico isolado, vetor de expressão, célula hospedeira recombinante, composição e método para limpeza de um item ou de uma superfície em necessidade de limpeza BR112012014082B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US28512709P 2009-12-09 2009-12-09
US61/285,127 2009-12-09
US39237310P 2010-10-12 2010-10-12
US61/392,373 2010-10-12
PCT/US2010/059628 WO2011072099A2 (en) 2009-12-09 2010-12-09 Compositions and methods comprising protease variants

Publications (2)

Publication Number Publication Date
BR112012014082A2 true BR112012014082A2 (pt) 2017-05-23
BR112012014082B1 BR112012014082B1 (pt) 2020-12-15

Family

ID=44146173

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012014082-5A BR112012014082B1 (pt) 2009-12-09 2010-12-09 variante de protease isolada e seu método de produção, ácido nucleico isolado, vetor de expressão, célula hospedeira recombinante, composição e método para limpeza de um item ou de uma superfície em necessidade de limpeza

Country Status (12)

Country Link
US (5) US8728790B2 (pt)
EP (3) EP2510094B1 (pt)
JP (4) JP5863666B2 (pt)
CN (2) CN102762222B (pt)
AR (1) AR079338A1 (pt)
AU (1) AU2010328121A1 (pt)
BR (1) BR112012014082B1 (pt)
CA (1) CA2782891C (pt)
DK (2) DK2510094T3 (pt)
ES (1) ES2746931T3 (pt)
MX (2) MX338884B (pt)
WO (1) WO2011072099A2 (pt)

Families Citing this family (161)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090060933A1 (en) * 2004-06-14 2009-03-05 Estell David A Proteases producing an altered immunogenic response and methods of making and using the same
JP2011524166A (ja) * 2008-06-06 2011-09-01 ダニスコ・ユーエス・インク 変異体微生物プロテアーゼを含む組成物及び方法
ES2625354T3 (es) * 2010-04-15 2017-07-19 Danisco Us Inc. Composiciones y métodos que comprenden variantes de proteasas
MX336737B (es) * 2010-05-06 2016-01-29 Danisco Us Inc Composiciones y metodos que comprenden variantes de proteasa serina.
MX357386B (es) * 2011-05-05 2018-07-06 Procter & Gamble Composiciones y metodos que comprenden variantes de proteasa serina.
CN103764823B (zh) * 2011-05-05 2018-05-11 丹尼斯科美国公司 包含丝氨酸蛋白酶变体的组合物和方法
EP2535401B1 (en) 2011-06-17 2017-01-25 Dalli-Werke GmbH & Co. KG Detergent composition comprising soil-release polymers of improved storage stability
US20130123162A1 (en) * 2011-11-10 2013-05-16 The Procter & Gamble Company Consumer products
US20140335596A1 (en) * 2011-12-20 2014-11-13 Novozymes A/S Subtilase Variants and Polynucleotides Encoding Same
US9309657B2 (en) * 2012-09-14 2016-04-12 Impact Products, Llc Floor mat
WO2014099525A1 (en) 2012-12-21 2014-06-26 Danisco Us Inc. Paenibacillus curdlanolyticus amylase, and methods of use, thereof
DK3354728T3 (da) 2012-12-21 2020-07-27 Danisco Us Inc Alpha-amylase-varianter
CN105229147B (zh) 2013-03-11 2020-08-11 丹尼斯科美国公司 α-淀粉酶组合变体
EP4159854A1 (en) 2013-05-29 2023-04-05 Danisco US Inc Novel metalloproteases
US20160160202A1 (en) 2013-05-29 2016-06-09 Danisco Us Inc. Novel metalloproteases
US20160108387A1 (en) 2013-05-29 2016-04-21 Danisco Us Inc. Novel metalloproteases
EP3882346A1 (en) 2013-05-29 2021-09-22 Danisco US Inc. Novel metalloproteases
WO2014200657A1 (en) 2013-06-13 2014-12-18 Danisco Us Inc. Alpha-amylase from streptomyces xiamenensis
WO2014200656A1 (en) 2013-06-13 2014-12-18 Danisco Us Inc. Alpha-amylase from streptomyces umbrinus
WO2014200658A1 (en) 2013-06-13 2014-12-18 Danisco Us Inc. Alpha-amylase from promicromonospora vindobonensis
WO2014204596A1 (en) 2013-06-17 2014-12-24 Danisco Us Inc. Alpha-amylase from bacillaceae family member
WO2015014803A1 (en) * 2013-07-29 2015-02-05 Novozymes A/S Protease variants and polynucleotides encoding same
WO2015014790A2 (en) * 2013-07-29 2015-02-05 Novozymes A/S Protease variants and polynucleotides encoding same
DK3060659T3 (da) 2013-10-03 2019-09-09 Danisco Us Inc Alfa-amylaser fra exiguobacterium og fremgangsmåder til anvendelse deraf
EP3052622B1 (en) 2013-10-03 2018-09-19 Danisco US Inc. Alpha-amylases from a subset of exiguobacterium, and methods of use, thereof
WO2015057619A1 (en) 2013-10-15 2015-04-23 Danisco Us Inc. Clay granule
CN105980554B (zh) 2013-11-14 2022-05-13 丹尼斯科美国公司 通过减少糖化得到的稳定酶
EP3071691B1 (en) 2013-11-20 2019-10-23 Danisco US Inc. Variant alpha-amylases having reduced susceptibility to protease cleavage, and methods of use, thereof
TR201906371T4 (tr) 2013-12-13 2019-05-21 Danisco Inc Bacillus türlerinin serin proteazları.
EP3910057A1 (en) 2013-12-13 2021-11-17 Danisco US Inc. Serine proteases of the bacillus gibsonii-clade
KR20160099629A (ko) 2013-12-16 2016-08-22 이 아이 듀폰 디 네모아 앤드 캄파니 점도 조절제로서의 폴리 알파-1,3-글루칸 에테르의 사용
US9957334B2 (en) 2013-12-18 2018-05-01 E I Du Pont De Nemours And Company Cationic poly alpha-1,3-glucan ethers
WO2015123323A1 (en) 2014-02-14 2015-08-20 E. I. Du Pont De Nemours And Company Poly-alpha-1,3-1,6-glucans for viscosity modification
CA2937830A1 (en) 2014-03-11 2015-09-17 E. I. Du Pont De Nemours And Company Oxidized poly alpha-1,3-glucan as detergent builder
DK3119884T3 (da) 2014-03-21 2019-10-14 Danisco Us Inc Serinproteaser af bacillus-arter
WO2015144936A1 (en) * 2014-03-28 2015-10-01 Novozymes A/S Resolubilization of protein crystals at low ph
US9714403B2 (en) 2014-06-19 2017-07-25 E I Du Pont De Nemours And Company Compositions containing one or more poly alpha-1,3-glucan ether compounds
EP3919599A1 (en) 2014-06-19 2021-12-08 Nutrition & Biosciences USA 4, Inc. Compositions containing one or more poly alpha-1,3-glucan ether compounds
US10138268B2 (en) 2014-10-10 2018-11-27 Enzypep B.V. Peptide fragment condensation and cyclisation using a subtilisin variant with improved synthesis over hydrolysis ratio
EP3207129B1 (en) 2014-10-17 2019-11-20 Danisco US Inc. Serine proteases of bacillus species
EP3172329A1 (en) 2014-10-24 2017-05-31 Danisco US Inc. Method for producing alcohol by use of a tripeptidyl peptidase
WO2016069557A1 (en) 2014-10-27 2016-05-06 Danisco Us Inc. Serine proteases of bacillus species
WO2016069548A2 (en) 2014-10-27 2016-05-06 Danisco Us Inc. Serine proteases
DK3212662T3 (da) 2014-10-27 2020-07-20 Danisco Us Inc Serinproteaser
EP3957729A1 (en) 2014-10-27 2022-02-23 Danisco US Inc. Serine proteases
EP3212783B1 (en) 2014-10-27 2024-06-26 Danisco US Inc. Serine proteases
AU2015369965B2 (en) 2014-12-23 2020-01-30 Nutrition & Biosciences USA 4, Inc. Enzymatically produced cellulose
WO2016183509A1 (en) 2015-05-13 2016-11-17 Danisco Us Inc. AprL-CLADE PROTEASE VARIANTS AND USES THEREOF
WO2016201040A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc. Water-triggered enzyme suspension
WO2016201069A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc Low-density enzyme-containing particles
FI3307427T3 (fi) 2015-06-09 2023-11-09 Danisco Us Inc Osmoottiset puhkeavat kapselit
US11499146B2 (en) 2015-06-17 2022-11-15 Danisco Us Inc. Bacillus gibsonii-clade serine proteases
US20180320158A1 (en) 2015-11-05 2018-11-08 Danisco Us Inc. Paenibacillus and bacillus spp. mannanases
JP7364331B2 (ja) * 2015-11-05 2023-10-18 ダニスコ・ユーエス・インク パエニバチルス(Paenibacillus)属種マンナナーゼ
EP3374401B1 (en) 2015-11-13 2022-04-06 Nutrition & Biosciences USA 4, Inc. Glucan fiber compositions for use in laundry care and fabric care
EP3374400B1 (en) 2015-11-13 2022-04-13 Nutrition & Biosciences USA 4, Inc. Glucan fiber compositions for use in laundry care and fabric care
JP6997706B2 (ja) 2015-11-13 2022-01-18 ニュートリション・アンド・バイオサイエンシーズ・ユーエスエー・フォー,インコーポレイテッド 洗濯ケアおよび織物ケアにおいて使用するためのグルカン繊維組成物
DE102015223270A1 (de) * 2015-11-25 2017-06-01 Henkel Ag & Co. Kgaa Proteasevarianten mit verbesserter Enzymstabilität in Wasch- und Reinigungsmitteln
BR112018010475B1 (pt) 2015-11-25 2023-02-14 Unilever Ip Holdings B.V. Composição de detergente líquido e método de lavagem de roupas utilizando uma composição de detergente líquido para lavar roupas
EP3387124B1 (en) 2015-12-09 2021-05-19 Danisco US Inc. Alpha-amylase combinatorial variants
EP3390625B1 (en) 2015-12-18 2023-09-06 Danisco US Inc. Polypeptides with endoglucanase activity and uses thereof
US11447782B2 (en) 2016-03-04 2022-09-20 Danisco Us Inc. Engineered ribosomal promoters for protein production in microorganisms
WO2017173190A2 (en) 2016-04-01 2017-10-05 Danisco Us Inc. Alpha-amylases, compositions & methods
WO2017173324A2 (en) 2016-04-01 2017-10-05 Danisco Us Inc. Alpha-amylases, compositions & methods
DE102016205670A1 (de) 2016-04-06 2017-10-12 Henkel Ag & Co. Kgaa Neue Protease mit verbesserter Waschleistung
CN109715791B (zh) 2016-05-03 2023-07-14 丹尼斯科美国公司 蛋白酶变体及其用途
EP3845642B1 (en) 2016-05-05 2023-08-09 Danisco US Inc. Protease variants and uses thereof
CN109477112B (zh) 2016-05-31 2024-09-06 丹尼斯科美国公司 蛋白酶变体及其用途
JP7152319B2 (ja) * 2016-06-17 2022-10-12 ダニスコ・ユーエス・インク プロテアーゼ変異体およびその使用
EP3497199A1 (en) 2016-08-08 2019-06-19 Basf Se Liquid laundry formulation
EP3535365A2 (en) 2016-11-07 2019-09-11 Danisco US Inc. Laundry detergent composition
CN110023475A (zh) 2016-12-01 2019-07-16 巴斯夫欧洲公司 酶在组合物中的稳定化
CA3045106A1 (en) * 2016-12-16 2018-06-21 Carbios Improved plastic degrading proteases
CN110312795B (zh) 2016-12-21 2024-07-23 丹尼斯科美国公司 蛋白酶变体及其用途
EP4212622A3 (en) 2016-12-21 2023-11-29 Danisco US Inc. Bacillus gibsonii-clade serine proteases
US20200040283A1 (en) 2017-03-31 2020-02-06 Danisco Us Inc Delayed release enzyme formulations for bleach-containing detergents
US20210095268A1 (en) 2017-03-31 2021-04-01 Danisco Us Inc Alpha-amylase combinatorial variants
JP6748895B2 (ja) 2017-04-13 2020-09-02 パナソニックIpマネジメント株式会社 水耕栽培装置
EP3404036A1 (en) * 2017-05-19 2018-11-21 Enzypep B.V. Subtilisin variants having a mutation in the s2 or s2' pocket
EP3645696A1 (en) 2017-06-30 2020-05-06 Danisco US Inc. Low-agglomeration, enzyme-containing particles
CN111212906B (zh) 2017-08-18 2024-02-02 丹尼斯科美国公司 α-淀粉酶变体
WO2019089898A1 (en) 2017-11-02 2019-05-09 Danisco Us Inc Freezing point depressed solid matrix compositions for melt granulation of enzymes
US20200354708A1 (en) * 2017-11-29 2020-11-12 Danisco Us Inc. Subtilisin variants having improved stability
MX2020005661A (es) 2017-11-29 2020-08-20 Basf Se Preparaciones de enzimas estables en almacenamiento, su produccion y uso.
US12134791B2 (en) 2017-12-21 2024-11-05 Danisco Us Inc. Enzyme-containing, hot-melt granules comprising a thermotolerant desiccant
WO2019156670A1 (en) 2018-02-08 2019-08-15 Danisco Us Inc. Thermally-resistant wax matrix particles for enzyme encapsulation
CN112368375A (zh) 2018-04-26 2021-02-12 巴斯夫欧洲公司 脂肪酶
EP3788145A1 (en) 2018-05-03 2021-03-10 Basf Se Amylase enzymes
CN110607291B (zh) * 2018-06-14 2022-05-31 青岛蔚蓝生物集团有限公司 耐热木聚糖酶突变体
WO2019238761A1 (en) 2018-06-15 2019-12-19 Basf Se Water soluble multilayer films containing wash active chemicals and enzymes
WO2019245704A1 (en) 2018-06-19 2019-12-26 Danisco Us Inc Subtilisin variants
US20210363470A1 (en) 2018-06-19 2021-11-25 Danisco Us Inc Subtilisin variants
CN108795906B (zh) * 2018-07-02 2022-02-22 四川德博尔制药有限公司 用于水解蛋壳膜的复合酶、蛋壳膜的水解方法、蛋壳膜水解产物及其提取方法
MX2021001213A (es) 2018-07-31 2021-08-24 Danisco Us Inc Variantes de alfa-amilasas que tienen sustituciones de aminoácidos que bajan el pka del ácido general.
WO2020030623A1 (en) 2018-08-10 2020-02-13 Basf Se Packaging unit comprising a detergent composition containing an enzyme and at least one chelating agent
WO2020047215A1 (en) 2018-08-30 2020-03-05 Danisco Us Inc Enzyme-containing granules
WO2020068486A1 (en) 2018-09-27 2020-04-02 Danisco Us Inc Compositions for medical instrument cleaning
EP3677676A1 (en) 2019-01-03 2020-07-08 Basf Se Compounds stabilizing amylases in liquids
JP7531964B2 (ja) 2018-10-05 2024-08-13 ベーアーエスエフ・エスエー 液体中のアミラーゼを安定化する化合物
BR112021005412A2 (pt) 2018-10-05 2021-06-15 Basf Se preparação de enzima, processo para fabricar uma preparação de enzima estável, métodos para reduzir a perda da atividade proteolítica, para preparação de uma formulação detergente, para remover manchas e para aumentar a estabilidade na armazenagem de uma formulação detergente líquida, usos de um composto e da preparação de enzima, e, formulação detergente
MX2021003932A (es) 2018-10-05 2021-06-04 Basf Se Compuestos estabilizadores de hidrolasas en liquidos.
US20220025355A1 (en) * 2018-10-10 2022-01-27 Shangrao Concord Pharmaceutical Co., Ltd Method for screening protease variant and obtained protease variant
WO2020077331A2 (en) 2018-10-12 2020-04-16 Danisco Us Inc Alpha-amylases with mutations that improve stability in the presence of chelants
CN112961853B (zh) * 2018-11-02 2024-09-06 中国科学院动物研究所 基于C2c1核酸酶的基因组编辑系统和方法
WO2020104231A1 (en) 2018-11-19 2020-05-28 Basf Se Powders and granules containing a chelating agent and an enzyme
WO2020112599A1 (en) 2018-11-28 2020-06-04 Danisco Us Inc Subtilisin variants having improved stability
EP3891277A1 (en) * 2018-12-03 2021-10-13 Novozymes A/S Powder detergent compositions
EP3927809A1 (en) 2019-02-20 2021-12-29 Basf Se Industrial fermentation process for bacillus using defined medium and trace element feed
US20220186177A1 (en) 2019-02-20 2022-06-16 Basf Se Industrial fermentation process for bacillus using defined medium and magnesium feed
EP3702452A1 (en) * 2019-03-01 2020-09-02 Novozymes A/S Detergent compositions comprising two proteases
JP7209348B2 (ja) 2019-03-29 2023-01-20 パナソニックIpマネジメント株式会社 車両管理装置、車両管理方法及び車両
WO2020229480A1 (en) 2019-05-14 2020-11-19 Basf Se Compounds stabilizing hydrolases in liquids
US20220220419A1 (en) 2019-05-24 2022-07-14 Danisco Us Inc Subtilisin variants and methods of use
WO2020247582A1 (en) 2019-06-06 2020-12-10 Danisco Us Inc Methods and compositions for cleaning
CN113993878A (zh) 2019-06-13 2022-01-28 巴斯夫欧洲公司 用二价阳离子从发酵液中回收蛋白的方法
US20220267699A1 (en) 2019-07-01 2022-08-25 Basf Se Peptide acetals for stabilising enzymes
EP3994273A1 (en) 2019-07-02 2022-05-11 Basf Se Method for preparing a fermentation medium
MX2022000253A (es) 2019-07-05 2022-02-03 Basf Se Proceso de fermentacion industrial para celulas microbianas mediante el uso de un precultivo de alimentacion por lotes.
US20240132808A1 (en) 2019-10-18 2024-04-25 Basf Se Storage-Stable Hydrolase Containing Liquids
WO2021080948A2 (en) 2019-10-24 2021-04-29 Danisco Us Inc Variant maltopentaose/maltohexaose-forming alpha-amylases
EP4058553A1 (en) 2019-11-11 2022-09-21 Danisco US Inc. Compositions and methods for enhanced protein production in bacillus cells
WO2021105330A1 (en) 2019-11-29 2021-06-03 Basf Se Compositions and polymers useful for such compositions
WO2021115912A1 (en) 2019-12-09 2021-06-17 Basf Se Formulations comprising a hydrophobically modified polyethyleneimine and one or more enzymes
WO2021160818A1 (en) 2020-02-14 2021-08-19 Basf Se Mannanase variants
EP4168523B1 (en) 2020-06-18 2024-07-03 Basf Se Compositions and their use
JP2023537833A (ja) 2020-07-09 2023-09-06 ビーエーエスエフ ソシエタス・ヨーロピア 組成物及びその用途
WO2022008732A1 (en) 2020-07-10 2022-01-13 Basf Se Enhancing the activity of antimicrobial preservatives
EP4204553A1 (en) 2020-08-27 2023-07-05 Danisco US Inc. Enzymes and enzyme compositions for cleaning
WO2022043563A1 (en) * 2020-08-28 2022-03-03 Novozymes A/S Polyester degrading protease variants
WO2022083949A1 (en) 2020-10-20 2022-04-28 Basf Se Compositions and their use
WO2022106400A1 (en) * 2020-11-18 2022-05-27 Novozymes A/S Combination of immunochemically different proteases
CN112501149B (zh) * 2020-12-21 2022-03-18 天津科技大学 一种碱性蛋白酶突变体及其基因、工程菌、制备方法和应用
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections
WO2022165107A1 (en) 2021-01-29 2022-08-04 Danisco Us Inc Compositions for cleaning and methods related thereto
US20240294888A1 (en) 2021-06-30 2024-09-05 Danisco Us Inc. Variant enzymes and uses thereof
WO2023023644A1 (en) 2021-08-20 2023-02-23 Danisco Us Inc. Polynucleotides encoding novel nucleases, compositions thereof and methods thereof for eliminating dna from protein preparations
EP4396320A2 (en) 2021-09-03 2024-07-10 Danisco US Inc. Laundry compositions for cleaning
WO2023039270A2 (en) 2021-09-13 2023-03-16 Danisco Us Inc. Bioactive-containing granules
CN118202030A (zh) 2021-10-13 2024-06-14 巴斯夫欧洲公司 包含聚合物的组合物、聚合物及其用途
WO2023066741A1 (en) 2021-10-20 2023-04-27 Basf Se Phosphate-free composition and methods for their manufacture and use
CN118451167A (zh) 2021-11-22 2024-08-06 巴斯夫欧洲公司 包含聚合物的组合物、聚合物及其用途
CN118284680A (zh) 2021-11-22 2024-07-02 巴斯夫欧洲公司 包含聚合物的组合物、聚合物及其用途
WO2023114939A2 (en) 2021-12-16 2023-06-22 Danisco Us Inc. Subtilisin variants and methods of use
CN118715318A (zh) 2021-12-16 2024-09-27 丹尼斯科美国公司 枯草杆菌蛋白酶变体及其用途
WO2023114936A2 (en) 2021-12-16 2023-06-22 Danisco Us Inc. Subtilisin variants and methods of use
CA3241094A1 (en) 2021-12-16 2023-06-22 Jonathan LASSILA Variant maltopentaose/maltohexaose-forming alpha-amylases
CN118401646A (zh) 2021-12-17 2024-07-26 巴斯夫欧洲公司 组合物及其应用
CN118871456A (zh) 2022-01-13 2024-10-29 丹尼斯科美国公司 用于增强革兰氏阳性细菌细胞中的蛋白质产生的组合物和方法
WO2023168234A1 (en) 2022-03-01 2023-09-07 Danisco Us Inc. Enzymes and enzyme compositions for cleaning
WO2023250301A1 (en) 2022-06-21 2023-12-28 Danisco Us Inc. Methods and compositions for cleaning comprising a polypeptide having thermolysin activity
WO2024012894A1 (en) 2022-07-15 2024-01-18 Basf Se Alkanolamine formates for enzyme stabilization in liquid formulations
WO2024050339A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. Mannanase variants and methods of use
WO2024050346A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. Detergent compositions and methods related thereto
WO2024050343A1 (en) 2022-09-02 2024-03-07 Danisco Us Inc. Subtilisin variants and methods related thereto
WO2024083589A1 (en) 2022-10-18 2024-04-25 Basf Se Detergent compositions, polymers and methods of manufacturing the same
WO2024102698A1 (en) 2022-11-09 2024-05-16 Danisco Us Inc. Subtilisin variants and methods of use
EP4389864A1 (en) 2022-12-20 2024-06-26 Basf Se Cutinases
WO2024163600A1 (en) * 2023-02-01 2024-08-08 Danisco Us Inc. Subtilisin variants and methods of use
WO2024163584A1 (en) 2023-02-01 2024-08-08 Danisco Us Inc. Subtilisin variants and methods of use
WO2024186819A1 (en) 2023-03-06 2024-09-12 Danisco Us Inc. Subtilisin variants and methods of use
WO2024191711A1 (en) 2023-03-16 2024-09-19 Nutrition & Biosciences USA 4, Inc. Brevibacillus fermentate extracts for cleaning and malodor control and use thereof

Family Cites Families (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1296839A (pt) 1969-05-29 1972-11-22
GB1372034A (en) 1970-12-31 1974-10-30 Unilever Ltd Detergent compositions
GB2048606B (en) 1979-02-28 1983-03-16 Barr & Stroud Ltd Optical scanning system
US4302544A (en) 1979-10-15 1981-11-24 University Of Rochester Asporogenous mutant of B. subtilis for use as host component of HV1 system
DK187280A (da) 1980-04-30 1981-10-31 Novo Industri As Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode
GR76237B (pt) 1981-08-08 1984-08-04 Procter & Gamble
US4450235A (en) 1982-04-21 1984-05-22 Cpc International Inc. Asporogenic mutant of bacillus subtilis useful as a host in a host-vector system
US4561998A (en) 1982-05-24 1985-12-31 The Procter & Gamble Company Near-neutral pH detergents containing anionic surfactant, cosurfactant and fatty acid
US4550862A (en) 1982-11-17 1985-11-05 The Procter & Gamble Company Liquid product pouring and measuring package with self draining feature
US4597898A (en) 1982-12-23 1986-07-01 The Proctor & Gamble Company Detergent compositions containing ethoxylated amines having clay soil removal/anti-redeposition properties
US4760025A (en) 1984-05-29 1988-07-26 Genencor, Inc. Modified enzymes and methods for making same
US4515707A (en) 1983-06-27 1985-05-07 The Chemithon Corporation Intermediate product for use in producing a detergent bar and method for producing same
ES8608579A1 (es) 1983-07-06 1986-06-16 Gist Brocades Nv Procedimiento para introducir dna en un anfitrion de cepa de microorganismo unicelular
US4515705A (en) 1983-11-14 1985-05-07 The Procter & Gamble Company Compositions containing odor purified proteolytic enzymes and perfumes
US4537706A (en) 1984-05-14 1985-08-27 The Procter & Gamble Company Liquid detergents containing boric acid to stabilize enzymes
US5264366A (en) 1984-05-29 1993-11-23 Genencor, Inc. Protease deficient bacillus
US5763257A (en) 1984-05-29 1998-06-09 Genencor International, Inc. Modified subtilisins having amino acid alterations
US5155033A (en) * 1989-01-06 1992-10-13 Genencor, Inc. Subtilisins modified at position 225 resulting in a shift in catalytic activity
US5972682A (en) 1984-05-29 1999-10-26 Genencor International, Inc. Enzymatically active modified subtilisins
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
DK171161B1 (da) 1985-03-28 1996-07-08 Hoffmann La Roche Fremgangsmåde til påvisning af forekomst eller fravær af mindst én specifik nukleinsyresekvens i en prøve eller til skelnen mellem to forskellige nukleinsyresekvenser i denne prøve
DK154572C (da) 1985-08-07 1989-04-24 Novo Industri As Enzymatisk detergentadditiv, detergent og fremgangsmaade til vask af tekstiler
EP0218272B1 (en) 1985-08-09 1992-03-18 Gist-Brocades N.V. Novel lipolytic enzymes and their use in detergent compositions
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
ES2058119T3 (es) 1986-08-29 1994-11-01 Novo Nordisk As Aditivo detergente enzimatico.
GB8629837D0 (en) 1986-12-13 1987-01-21 Interox Chemicals Ltd Bleach activation
US4765916A (en) 1987-03-24 1988-08-23 The Clorox Company Polymer film composition for rinse release of wash additives
US4972017A (en) 1987-03-24 1990-11-20 The Clorox Company Rinse soluble polymer film composition for wash additives
WO1988009367A1 (en) 1987-05-29 1988-12-01 Genencor, Inc. Cutinase cleaning composition
DE3854249T2 (de) 1987-08-28 1996-02-29 Novonordisk As Rekombinante Humicola-Lipase und Verfahren zur Herstellung von rekombinanten Humicola-Lipasen.
JPS6474992A (en) 1987-09-16 1989-03-20 Fuji Oil Co Ltd Dna sequence, plasmid and production of lipase
EP0471265B1 (en) 1988-01-07 1995-10-25 Novo Nordisk A/S Specific protease
JP3079276B2 (ja) 1988-02-28 2000-08-21 天野製薬株式会社 組換え体dna、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法
US4977252A (en) 1988-03-11 1990-12-11 National Starch And Chemical Investment Holding Corporation Modified starch emulsifier characterized by shelf stability
US4968451A (en) 1988-08-26 1990-11-06 The Procter & Gamble Company Soil release agents having allyl-derived sulfonated end caps
WO1990009446A1 (en) 1989-02-17 1990-08-23 Plant Genetic Systems N.V. Cutinase
JP3220137B2 (ja) 1989-08-25 2001-10-22 ヘンケル・リサーチ・コーポレイション アルカリ性タンパク質分解酵素およびその製造方法
KR100236540B1 (ko) 1990-04-14 2000-01-15 레클로우크스 라우에르 알카리성 바실러스-리파제, 이를 코-딩하는 dna 서열 및 리파제를 생산하는 바실러스 균주
US5354559A (en) 1990-05-29 1994-10-11 Grain Processing Corporation Encapsulation with starch hydrolyzate acid esters
ATE219136T1 (de) 1991-01-16 2002-06-15 Procter & Gamble Kompakte waschmittelzusammensetzungen mit hochaktiven cellulasen
GB9108136D0 (en) 1991-04-17 1991-06-05 Unilever Plc Concentrated detergent powder compositions
US5340735A (en) 1991-05-29 1994-08-23 Cognis, Inc. Bacillus lentus alkaline protease variants with increased stability
ATE237681T1 (de) 1992-12-01 2003-05-15 Novozymes As Beschleunigung von enzymreaktionen
CA2154157C (en) 1993-01-18 1999-08-03 Fiona Susan Macbeath Machine dishwashing detergent compositions
US5888954A (en) 1993-05-08 1999-03-30 Henkel Kommanditgesellschaft Auf Aktien Corrosion inhibitors for silver
CA2162459A1 (en) 1993-05-08 1994-11-24 Juergen Haerer Corrosion inhibitors for silver (ii)
EP0697035B1 (de) 1993-05-08 1998-02-11 Henkel Kommanditgesellschaft auf Aktien Silberkorrosionsschutzmittel i
DK77393D0 (da) 1993-06-29 1993-06-29 Novo Nordisk As Aktivering af enzymer
US5698504A (en) 1993-07-01 1997-12-16 The Procter & Gamble Company Machine dishwashing composition containing oxygen bleach and paraffin oil and benzotriazole compound silver tarnishing inhibitors
US5486303A (en) 1993-08-27 1996-01-23 The Procter & Gamble Company Process for making high density detergent agglomerates using an anhydrous powder additive
US6436690B1 (en) 1993-09-15 2002-08-20 The Procter & Gamble Company BPN′ variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted
DE4342680A1 (de) 1993-12-15 1995-06-22 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung für Medien
US5861271A (en) 1993-12-17 1999-01-19 Fowler; Timothy Cellulase enzymes and systems for their expressions
ES2364774T3 (es) 1994-02-24 2011-09-14 HENKEL AG & CO. KGAA Enzimas mejoradas y detergentes que las contienen.
US5691295A (en) 1995-01-17 1997-11-25 Cognis Gesellschaft Fuer Biotechnologie Mbh Detergent compositions
ES2302330T3 (es) 1994-02-24 2008-07-01 Henkel Kommanditgesellschaft Auf Aktien Enzimas mejoradas y detergentes que las contienen.
US5686014A (en) 1994-04-07 1997-11-11 The Procter & Gamble Company Bleach compositions comprising manganese-containing bleach catalysts
ZA952220B (en) * 1994-05-02 1995-12-14 Procter & Gamble Bpn' variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted
PE6995A1 (es) 1994-05-25 1995-03-20 Procter & Gamble Composicion que comprende un polimero de polialquilenoamina etoxilado propoxilado como agente de separacion de sucio
WO1995035362A1 (en) 1994-06-17 1995-12-28 Genencor International Inc. Cleaning compositions containing plant cell wall degrading enzymes and their use in cleaning methods
GB2294268A (en) 1994-07-07 1996-04-24 Procter & Gamble Bleaching composition for dishwasher use
US5879584A (en) 1994-09-10 1999-03-09 The Procter & Gamble Company Process for manufacturing aqueous compositions comprising peracids
US5516448A (en) 1994-09-20 1996-05-14 The Procter & Gamble Company Process for making a high density detergent composition which includes selected recycle streams for improved agglomerate
US5691297A (en) 1994-09-20 1997-11-25 The Procter & Gamble Company Process for making a high density detergent composition by controlling agglomeration within a dispersion index
US5489392A (en) 1994-09-20 1996-02-06 The Procter & Gamble Company Process for making a high density detergent composition in a single mixer/densifier with selected recycle streams for improved agglomerate properties
DE69515331T2 (de) 1994-12-09 2000-10-19 The Procter & Gamble Company, Cincinnati Diacylperoxydteilchen enthaltende zusammensetzungen für automatische geschirreinigung
US5534179A (en) 1995-02-03 1996-07-09 Procter & Gamble Detergent compositions comprising multiperacid-forming bleach activators
US5574005A (en) 1995-03-07 1996-11-12 The Procter & Gamble Company Process for producing detergent agglomerates from high active surfactant pastes having non-linear viscoelastic properties
US5569645A (en) 1995-04-24 1996-10-29 The Procter & Gamble Company Low dosage detergent composition containing optimum proportions of agglomerates and spray dried granules for improved flow properties
JP4592832B2 (ja) 1995-06-16 2010-12-08 ザ プロクター アンド ギャンブル カンパニー コバルト触媒を含む自動皿洗い組成物
US5597936A (en) 1995-06-16 1997-01-28 The Procter & Gamble Company Method for manufacturing cobalt catalysts
US5565422A (en) 1995-06-23 1996-10-15 The Procter & Gamble Company Process for preparing a free-flowing particulate detergent composition having improved solubility
US5576282A (en) 1995-09-11 1996-11-19 The Procter & Gamble Company Color-safe bleach boosters, compositions and laundry methods employing same
CA2232466C (en) 1995-09-18 2002-12-31 The Procter & Gamble Company Laundry and cleaning products delivery systems
MA24136A1 (fr) 1996-04-16 1997-12-31 Procter & Gamble Fabrication d'agents de surface .
US5929022A (en) 1996-08-01 1999-07-27 The Procter & Gamble Company Detergent compositions containing amine and specially selected perfumes
CN1263759C (zh) 1997-03-07 2006-07-12 宝洁公司 制备交联桥大环化合物的改进方法
US6306812B1 (en) 1997-03-07 2001-10-23 Procter & Gamble Company, The Bleach compositions containing metal bleach catalyst, and bleach activators and/or organic percarboxylic acids
GB2327947A (en) 1997-08-02 1999-02-10 Procter & Gamble Detergent tablet
US6376445B1 (en) 1997-08-14 2002-04-23 Procter & Gamble Company Detergent compositions comprising a mannanase and a protease
DE19736591A1 (de) 1997-08-22 1999-02-25 Peter Prof Dr Hegemann Verfahren zum Herstellen von Nukleinsäurepolymeren
MA24811A1 (fr) 1997-10-23 1999-12-31 Procter & Gamble Compositions de lavage contenant des variantes de proteases multisubstituees
US5935826A (en) 1997-10-31 1999-08-10 National Starch And Chemical Investment Holding Corporation Glucoamylase converted starch derivatives and their use as emulsifying and encapsulating agents
US6287839B1 (en) 1997-11-19 2001-09-11 Genencor International, Inc. Cellulase producing actinomycetes, cellulase produced therefrom and method of producing same
WO1999027082A1 (en) 1997-11-21 1999-06-03 Novo Nordisk A/S Protease variants and compositions
AU2207099A (en) 1997-12-24 1999-07-19 Genencor International, Inc. An improved method of assaying for a preferred enzyme and/or preferred detergentcomposition
US6642011B2 (en) * 1998-04-15 2003-11-04 Genencor International, Inc. Human protease and use of such protease for pharmaceutical applications and for reducing the allergenicity of non-human proteins
CN101024826B (zh) 1998-06-10 2014-09-03 诺沃奇梅兹有限公司 新的甘露聚糖酶
US6376450B1 (en) 1998-10-23 2002-04-23 Chanchal Kumar Ghosh Cleaning compositions containing multiply-substituted protease variants
US6294514B1 (en) 1998-11-24 2001-09-25 The Procter & Gamble Company Process for preparing mono-long chain amine oxide surfactants with low nitrite, nitrosamine and low residual peroxide
WO2000032601A2 (en) 1998-11-30 2000-06-08 The Procter & Gamble Company Process for preparing cross-bridged tetraaza macrocycles
CZ2002212A3 (cs) * 1999-07-22 2002-07-17 The Procter & Gamble Company Varianty subtilisinové proteasy mající aminokyselinové substituce v definovaných epitopových oblastech
US6440991B1 (en) 2000-10-02 2002-08-27 Wyeth Ethers of 7-desmethlrapamycin
US6582914B1 (en) 2000-10-26 2003-06-24 Genencor International, Inc. Method for generating a library of oligonucleotides comprising a controlled distribution of mutations
AU2002254374A1 (en) * 2001-03-23 2002-10-08 Genencor International, Inc. Proteins producing an altered immunogenic response and methods of making and using the same
GB0114847D0 (en) 2001-06-18 2001-08-08 Unilever Plc Water soluble package and liquid contents thereof
CA2472206C (en) * 2001-12-31 2013-04-09 Genencor International, Inc. Proteases producing an altered immunogenic response and methods of making and using the same
US20050054843A1 (en) * 2001-12-31 2005-03-10 Estell David A Proteases producing an altered immunological response and methods of making and using the same
US7306937B2 (en) 2002-01-16 2007-12-11 Genencor International, Inc. Multiply-substituted protease variants
ATE457352T1 (de) * 2002-02-26 2010-02-15 Genencor Int Subtilisin-carlsberg-proteine mit verminderter immunogenität
US7557076B2 (en) 2002-06-06 2009-07-07 The Procter & Gamble Company Organic catalyst with enhanced enzyme compatibility
DE10260805A1 (de) 2002-12-23 2004-07-22 Geneart Gmbh Verfahren und Vorrichtung zum Optimieren einer Nucleotidsequenz zur Expression eines Proteins
US7294499B2 (en) 2003-01-30 2007-11-13 Novozymes A/S Subtilases
ES2299682T3 (es) 2003-05-23 2008-06-01 THE PROCTER & GAMBLE COMPANY Composicion limpiadora para usar en una lavadora o un lavavajillas.
EP1692158B1 (en) 2003-11-06 2011-10-26 Danisco US Inc. Vegf binding and supported peptides for treating skin diseases
EP2664670B1 (en) 2003-12-03 2015-05-06 Danisco US Inc. Perhydrolase
CN105200027B (zh) 2005-10-12 2019-05-31 金克克国际有限公司 储存稳定的中性金属蛋白酶的用途和制备
JP2010501024A (ja) 2006-06-05 2010-01-14 ザ プロクター アンド ギャンブル カンパニー 酵素安定剤
WO2008010925A2 (en) 2006-07-18 2008-01-24 Danisco Us, Inc., Genencor Division Protease variants active over a broad temperature range
WO2008153925A2 (en) * 2007-06-06 2008-12-18 Danisco Us, Inc., Genencor Division Methods for improving multiple protein properties
EP2100947A1 (en) 2008-03-14 2009-09-16 The Procter and Gamble Company Automatic dishwashing detergent composition
JP2011524166A (ja) 2008-06-06 2011-09-01 ダニスコ・ユーエス・インク 変異体微生物プロテアーゼを含む組成物及び方法
CN102652175B (zh) * 2009-12-09 2016-02-10 宝洁公司 织物和家居护理产品

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