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BR112017008406A2 - uso de tripeptidil peptidases tolerantes a prolina em composições de aditivo alimentar - Google Patents

uso de tripeptidil peptidases tolerantes a prolina em composições de aditivo alimentar

Info

Publication number
BR112017008406A2
BR112017008406A2 BR112017008406-6A BR112017008406A BR112017008406A2 BR 112017008406 A2 BR112017008406 A2 BR 112017008406A2 BR 112017008406 A BR112017008406 A BR 112017008406A BR 112017008406 A2 BR112017008406 A2 BR 112017008406A2
Authority
BR
Brazil
Prior art keywords
proline
food additive
tolerant tripeptidyl
proline tolerant
asparagine
Prior art date
Application number
BR112017008406-6A
Other languages
English (en)
Inventor
Haaning Svend
Matthias Kragh Karsten
Shipovskov Stepan
Miasnikov Andrei
Ma Maria
Fernando Romero Millan Luis
Barnard Luke
Yu Shukun
Meinjohanns Ernst
Yde Bak Steffen
Nurminen Paivi
Putaala Heli
Original Assignee
Dupont Nutrition Biosciences Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dupont Nutrition Biosciences Aps filed Critical Dupont Nutrition Biosciences Aps
Publication of BR112017008406A2 publication Critical patent/BR112017008406A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K10/00—Animal feeding-stuffs
    • A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
    • A23K10/14—Pretreatment of feeding-stuffs with enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
    • A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
    • A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof
    • A23K20/147—Polymeric derivatives, e.g. peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
    • A23K50/75—Feeding-stuffs specially adapted for particular animals for birds for poultry
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/485—Exopeptidases (3.4.11-3.4.19)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/14—Dipeptidyl-peptidases and tripeptidyl-peptidases (3.4.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/14—Dipeptidyl-peptidases and tripeptidyl-peptidases (3.4.14)
    • C12Y304/14009—Tripeptidyl-peptidase I (3.4.14.9)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Husbandry (AREA)
  • Birds (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Fodder In General (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • General Preparation And Processing Of Foods (AREA)

Abstract

a presente invenção refere-se a um método de preparação de uma composição de aditivo alimentar que compreende: (a) misturar pelo menos uma tripeptidil peptidase tolerante à prolina que tem predominantemente atividade de exopeptidase, em que a dita tripeptidil peptidase tolerante à prolina tem capacidade para clivar tripeptídeos a partir da terminação n de peptídeos que têm (i) (a) prolina em p1; e (b) um aminoácido selecionado a partir de alanina, arginina, asparagina, ácido aspártico, cisteína, glutamina, ácido glutâmico, glicina, histidina, isoleucina, leucina, lisina, metionina, fenilalanina, serina, treonina, triptofano, tirosina, valina ou aminoácidos sintéticos em p1; ou (ii) (a?) prolina em p1?; e (b') um aminoácido selecionado a partir de alanina, arginina, asparagina, ácido aspártico, cisteína, glutamina, ácido glutâmico, glicina, histidina, isoleucina, leucina, lisina, metionina, fenilalanina, serina, treonina, triptofano, tirosina, valina ou aminas ou aminoácidos sintéticos em p1'; e um ou mais ingredientes selecionados do grupo que consiste em: um sal, poliol incluindo sorbitol e glicerol, trigo ou um componente de trigo, acetato de sódio, triidrato de acetato de sódio, talco de sorbato de potássio, álcool polivi-nílico (pva), benzoato, sorbiato, 1,3-propano diol, glicose, parabenos, cloreto de sódio, citrato, metabissulfito, formiato ou uma combinação dos mesmos; e (b) opcionalmente embalagem, bem como usos de tais tripeptidil peptidases tolerantes à prolina, composições de aditivos alimentares, kits de aditivos alimentares, alimentos ou rações e/ou pré-misturas.
BR112017008406-6A 2014-10-24 2015-10-23 uso de tripeptidil peptidases tolerantes a prolina em composições de aditivo alimentar BR112017008406A2 (pt)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201462068282P 2014-10-24 2014-10-24
US201462068243P 2014-10-24 2014-10-24
US201462068264P 2014-10-24 2014-10-24
US62/068,282 2014-10-24
US62/068,243 2014-10-24
US62/068,264 2014-10-24
US201462093301P 2014-12-17 2014-12-17
US62/093,301 2014-12-17
PCT/EP2015/074602 WO2016062857A1 (en) 2014-10-24 2015-10-23 Use of proline tolerant tripeptidyl peptidases in feed additive compositions

Publications (1)

Publication Number Publication Date
BR112017008406A2 true BR112017008406A2 (pt) 2018-02-27

Family

ID=54540018

Family Applications (2)

Application Number Title Priority Date Filing Date
BR112017008406-6A BR112017008406A2 (pt) 2014-10-24 2015-10-23 uso de tripeptidil peptidases tolerantes a prolina em composições de aditivo alimentar
BR112017008304-3A BR112017008304A2 (pt) 2014-10-24 2015-10-23 tripeptidil peptidases tolerantes à prolina e seus usos

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR112017008304-3A BR112017008304A2 (pt) 2014-10-24 2015-10-23 tripeptidil peptidases tolerantes à prolina e seus usos

Country Status (13)

Country Link
US (4) US20180295858A1 (pt)
EP (2) EP3209774B1 (pt)
JP (1) JP6878275B2 (pt)
CN (2) CN107105707B (pt)
AU (2) AU2015334890B2 (pt)
BR (2) BR112017008406A2 (pt)
CA (2) CA2965423A1 (pt)
DK (2) DK3209774T3 (pt)
ES (1) ES2791891T3 (pt)
MX (2) MX2017005256A (pt)
RU (1) RU2741080C2 (pt)
WO (2) WO2016062857A1 (pt)
ZA (1) ZA201702889B (pt)

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WO2018005229A1 (en) 2016-06-30 2018-01-04 Dupont Nutrition Biosciences Aps In feed assay of microbial proteases using peptide substrates
AU2017380099B2 (en) 2016-12-23 2024-07-11 Heidelberg Pharma Research Gmbh Amanitin antibody conjugates
CN111132556A (zh) 2017-06-09 2020-05-08 诺维信公司 用于对蛋白进行水解的多肽、用途和方法
CN107467370A (zh) * 2017-10-13 2017-12-15 无锡正大生物股份有限公司 一种饲料用功能性诱食剂及其制备方法
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Also Published As

Publication number Publication date
ZA201702889B (en) 2020-07-29
ES2791891T3 (es) 2020-11-06
EP3209773B1 (en) 2020-03-18
CN107105709A (zh) 2017-08-29
US20200245642A1 (en) 2020-08-06
AU2015334890A1 (en) 2017-05-04
JP6878275B2 (ja) 2021-05-26
RU2017117858A (ru) 2018-11-26
AU2015334892A1 (en) 2017-05-18
BR112017008304A2 (pt) 2018-05-15
US20220174981A1 (en) 2022-06-09
US20170325479A1 (en) 2017-11-16
WO2016062857A1 (en) 2016-04-28
DK3209774T3 (da) 2020-05-25
EP3209774B1 (en) 2020-02-26
EP3209774A1 (en) 2017-08-30
CN107105707A (zh) 2017-08-29
US20180295858A1 (en) 2018-10-18
WO2016062855A1 (en) 2016-04-28
CA2965423A1 (en) 2016-04-28
AU2015334890B2 (en) 2021-12-23
CN107105709B (zh) 2021-04-30
MX2017005268A (es) 2017-07-26
MX2017005256A (es) 2017-07-24
RU2017117858A3 (pt) 2019-09-18
DK3209773T3 (da) 2020-06-15
RU2741080C2 (ru) 2021-01-22
CN107105707B (zh) 2022-07-22
EP3209773A1 (en) 2017-08-30
JP2017534279A (ja) 2017-11-24
CA2965438A1 (en) 2016-04-28

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B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

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