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BR1100636A - Agente terapêutico para o mal de parkinson, e, derivado da xantina - Google Patents

Agente terapêutico para o mal de parkinson, e, derivado da xantina

Info

Publication number
BR1100636A
BR1100636A BR1100636-6A BR1100636A BR1100636A BR 1100636 A BR1100636 A BR 1100636A BR 1100636 A BR1100636 A BR 1100636A BR 1100636 A BR1100636 A BR 1100636A
Authority
BR
Brazil
Prior art keywords
group
parkinson
disease
carbon atoms
xanthine
Prior art date
Application number
BR1100636-6A
Other languages
English (en)
Inventor
Fumio Suzuki
Junichi Shimada
Akio Ishii
Shunji Ichikawa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to BR1100636-6A priority Critical patent/BR1100636A/pt
Publication of BR1100636A publication Critical patent/BR1100636A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/12—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1, 3, and 7, e.g. caffeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BR1100636-6A 1992-04-08 1997-05-13 Agente terapêutico para o mal de parkinson, e, derivado da xantina BR1100636A (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BR1100636-6A BR1100636A (pt) 1992-04-08 1997-05-13 Agente terapêutico para o mal de parkinson, e, derivado da xantina

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8711592 1992-04-08
BR1100636-6A BR1100636A (pt) 1992-04-08 1997-05-13 Agente terapêutico para o mal de parkinson, e, derivado da xantina

Publications (1)

Publication Number Publication Date
BR1100636A true BR1100636A (pt) 2000-04-18

Family

ID=13905960

Family Applications (1)

Application Number Title Priority Date Filing Date
BR1100636-6A BR1100636A (pt) 1992-04-08 1997-05-13 Agente terapêutico para o mal de parkinson, e, derivado da xantina

Country Status (11)

Country Link
EP (1) EP0565377B1 (pt)
JP (1) JP2613352B2 (pt)
AT (1) ATE161723T1 (pt)
BR (1) BR1100636A (pt)
CA (1) CA2093403C (pt)
DE (1) DE69316067T2 (pt)
DK (1) DK0565377T3 (pt)
ES (1) ES2112386T3 (pt)
GR (1) GR3026233T3 (pt)
HK (1) HK1001835A1 (pt)
NO (1) NO303265B1 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU664073B2 (en) * 1992-02-19 1995-11-02 Yukio Ishida Highly water absorbing rice, method of manufacturing same and utilization thereof
EP0628311B1 (en) * 1992-07-08 2002-04-24 Kyowa Hakko Kogyo Co., Ltd. Xanthine-Derivatives as Antidepressants
JP2613355B2 (ja) * 1992-09-28 1997-05-28 協和醗酵工業株式会社 パーキンソン氏病治療剤
AU6781194A (en) * 1993-05-03 1994-11-21 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The 8-substituted 1,3,7-trialkyl-xanthine derivatives as a2-selective adenosine receptor antagonists
PT711282E (pt) * 1993-07-28 2002-11-29 Aventis Pharma Ltd Compostos inibidores de pde iv e de fnt
WO1995023148A1 (fr) * 1994-02-23 1995-08-31 Kyowa Hakko Kogyo Co., Ltd. Derive de la xanthine
SI0958821T1 (en) * 1996-08-07 2005-02-28 Kyowa Hakko Kogyo Co., Ltd. Fat emulsion containing xanthine derivative
EP1016407B1 (en) * 1997-09-05 2006-05-10 Kyowa Hakko Kogyo Co., Ltd. Xanthine derivatives for treating brain ischemia
WO2003037860A2 (en) 2001-10-30 2003-05-08 Conforma Therapeutics Corporation Purine analogs having hsp90-inhibiting activity
KR20060004959A (ko) 2003-04-25 2006-01-16 노바카르디아, 인코포레이션 신장 기능 저하를 갖는 개별 대상자의 이뇨 작용 개선 방법
JP2007505933A (ja) 2003-09-18 2007-03-15 コンフォーマ・セラピューティクス・コーポレイション Ｈｓｐ９０インヒビターとしての新規なヘテロ環化合物
EP1709967A4 (en) 2004-01-28 2010-09-15 Kyowa Hakko Kirin Co Ltd MEDICINE AGAINST MIGRAINE
JP2008534609A (ja) * 2005-03-30 2008-08-28 コンフォーマ・セラピューティクス・コーポレイション Ｈｓｐ９０阻害剤としてのアルキニルピロロピリミジンおよび関連類似体
CA2608111A1 (en) * 2005-04-22 2006-11-02 Novacardia, Inc. Production of emulsions for intravenous injection of water-insoluble pharmaceutical compositions
KR20090094465A (ko) * 2006-12-22 2009-09-07 슈바르츠 파르마 악티엔게젤샤프트 선택적 ａ2ａ 수용체 안타고니스토로서의 8-알키닐잔틴 유도체
US7994357B2 (en) * 2009-04-03 2011-08-09 Naturewise Biotech & Medicals Corporation Cinamic compounds and derivatives therefrom for the inhibition of histone deacetylase
CN110981876B (zh) * 2018-12-21 2021-10-01 广东东阳光药业有限公司 8-取代的苯乙烯基黄嘌呤衍生物及其用途
CN111333648B (zh) * 2019-04-24 2021-05-11 东莞市东阳光新药研发有限公司 8-取代的芳香环乙烯基黄嘌呤衍生物及其用途
CN110041331B (zh) * 2019-05-17 2020-08-07 广东东阳光药业有限公司 苯乙烯基黄嘌呤衍生物及其用途
CN112409360B (zh) * 2019-08-22 2022-12-23 广东东阳光药业有限公司 杂芳基乙烯基黄嘌呤衍生物及其用途
CN112300165B (zh) * 2019-11-11 2022-03-04 广东东阳光药业有限公司 8-取代的苯乙烯基黄嘌呤衍生物及其用途
CN111072663B (zh) * 2019-12-12 2021-10-01 广东东阳光药业有限公司 8-取代的苯乙烯基黄嘌呤衍生物及其用途
CN111018856B (zh) * 2019-12-12 2021-10-01 广东东阳光药业有限公司 8-取代的苯乙烯基黄嘌呤衍生物及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT297021B (de) * 1969-07-30 1972-03-10 Parke Davis & Co Verfahren zur Herstellung neuer Xanthinverbindungen
DE3843117A1 (de) * 1988-12-22 1990-06-28 Boehringer Ingelheim Kg Neue xanthinderivate mit adenosin-antagonistischer wirkung
GB8906792D0 (en) * 1989-03-23 1989-05-10 Beecham Wuelfing Gmbh & Co Kg Treatment and compounds
DE4019892A1 (de) * 1990-06-22 1992-01-02 Boehringer Ingelheim Kg Neue xanthinderivate
FR2665636B1 (fr) * 1990-08-10 1994-10-07 Adir Utilisation d'un derive de la trimethyl-1,3,7 xanthine pour le traitement des troubles de la memoire, des troubles intellectuels de la senescence et de la maladie d'alzheimer.
ES2130138T3 (es) * 1990-10-18 1999-07-01 Kyowa Hakko Kogyo Kk Derivado de xantina.

Also Published As

Publication number Publication date
DE69316067D1 (de) 1998-02-12
JPH0616559A (ja) 1994-01-25
NO931317L (no) 1993-10-11
HK1001835A1 (en) 1998-07-10
EP0565377B1 (en) 1998-01-07
EP0565377A1 (en) 1993-10-13
ATE161723T1 (de) 1998-01-15
NO303265B1 (no) 1998-06-22
GR3026233T3 (en) 1998-05-29
CA2093403A1 (en) 1993-10-09
NO931317D0 (no) 1993-04-06
CA2093403C (en) 1999-08-10
JP2613352B2 (ja) 1997-05-28
DE69316067T2 (de) 1998-07-02
ES2112386T3 (es) 1998-04-01
DK0565377T3 (da) 1998-03-16

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Legal Events

Date Code Title Description
AN Processing applications according to articles 230 and 231 of law 9279/96: notification of filing an application
HHFK Processing applications according to articles 230 and 231 of law 9.279/96: republication
MT Patent procedure suspended until requirement met - articles 230 and 231 of law 9279/96
FGAN Processing applications according to articles 230 and 231 of law 9.279/96: granting
TKX1 Grant procedure suspended (cancelled) - according to articles 230 and 231 of law 9279/96
NB Patent issued - articles 230 and 231 of law 9279/96