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BR0314647A - Uso de derivados de 4-piridilmetil-ftalazina para a preparação de um medicamento para o tratamento de sìndromes melodisplásicas - Google Patents

Uso de derivados de 4-piridilmetil-ftalazina para a preparação de um medicamento para o tratamento de sìndromes melodisplásicas

Info

Publication number
BR0314647A
BR0314647A BR0314647-2A BR0314647A BR0314647A BR 0314647 A BR0314647 A BR 0314647A BR 0314647 A BR0314647 A BR 0314647A BR 0314647 A BR0314647 A BR 0314647A
Authority
BR
Brazil
Prior art keywords
syndromes
pyridylmethylphthalazine
melodysplastic
medicament
derivatives
Prior art date
Application number
BR0314647-2A
Other languages
English (en)
Inventor
Margaret Han Dugan
Alan List
Original Assignee
Novartis Ag
Univ Arizona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Univ Arizona filed Critical Novartis Ag
Publication of BR0314647A publication Critical patent/BR0314647A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/502—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"USO DE DERIVADOS DE 4-PIRIDILMETIL-FTALAZINA PARA A PREPARAçãO DE UM MEDICAMENTO PARA O TRATAMENTO DE SìNDROMES MIELODISPLáSICAS". A presente invenção refere-se a um método para tratar síndromes mielodisplásicas compreendendo administrar uma quantidade terapeuticamente eficaz de um derivado de 4-piridilmetil-ftalazina a um animal de sangue quente que necessite da mesma.
BR0314647-2A 2002-09-24 2003-09-23 Uso de derivados de 4-piridilmetil-ftalazina para a preparação de um medicamento para o tratamento de sìndromes melodisplásicas BR0314647A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41317602P 2002-09-24 2002-09-24
PCT/EP2003/010578 WO2004028542A1 (en) 2002-09-24 2003-09-23 Use of 4-pyridylmethyl-phthalazine derivatives for the manufacture of a medicament for the treatment of myelodysplastic syndromes

Publications (1)

Publication Number Publication Date
BR0314647A true BR0314647A (pt) 2005-08-02

Family

ID=32043216

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0314647-2A BR0314647A (pt) 2002-09-24 2003-09-23 Uso de derivados de 4-piridilmetil-ftalazina para a preparação de um medicamento para o tratamento de sìndromes melodisplásicas

Country Status (22)

Country Link
US (1) US20060128716A1 (pt)
EP (1) EP1545534B1 (pt)
JP (1) JP2006502195A (pt)
KR (1) KR20050074450A (pt)
CN (1) CN100372535C (pt)
AT (1) ATE359789T1 (pt)
AU (1) AU2003299065B2 (pt)
BR (1) BR0314647A (pt)
CA (1) CA2499738A1 (pt)
CR (1) CR7754A (pt)
DE (1) DE60313344T2 (pt)
EC (1) ECSP055700A (pt)
ES (1) ES2285251T3 (pt)
HR (1) HRP20050281A2 (pt)
MX (1) MXPA05003161A (pt)
NO (1) NO20051936L (pt)
PL (1) PL374696A1 (pt)
PT (1) PT1545534E (pt)
RS (1) RS20050228A (pt)
RU (1) RU2353364C2 (pt)
WO (1) WO2004028542A1 (pt)
ZA (1) ZA200502212B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001519366A (ja) * 1997-10-15 2001-10-23 ポーラクス バイオファーマシュティカルズ，インコーポレーテッド ヒ素化合物を用いた、原発性および転移性の腫瘍性疾患を治療するための組成物および方法
US7915410B2 (en) 2005-09-09 2011-03-29 Bristol-Myers Squibb Company Acyclic IKur inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7132458B2 (en) * 1994-08-10 2006-11-07 Chemaphor Inc. Oxidized carotenoid fractions and ketoaldehyde useful as cell-differentiation inducers, cytostatic agents, and anti-tumor agents
CO4950519A1 (es) * 1997-02-13 2000-09-01 Novartis Ag Ftalazinas, preparaciones farmaceuticas que las comprenden y proceso para su preparacion
JP4673977B2 (ja) * 1999-03-30 2011-04-20 ノバルティス アーゲー 炎症性疾患治療用フタラジン誘導体
AR025068A1 (es) * 1999-08-10 2002-11-06 Bayer Corp Pirazinas sustituidas y piridazinas fusionadas, composicion farmaceutica que las comprenden, uso de dichos compuestos para la manufactura de un medicamentocon actividad inhibidora de angiogenesis
ES2438535T3 (es) * 1999-12-06 2014-01-17 Geistlich Pharma Ag Taurolidina o taurultamo para uso en el tratamiento de tumores de próstata, de colon, de pulmón y para el tratamiento del glioblastoma multiforme recurrente

Also Published As

Publication number Publication date
RU2353364C2 (ru) 2009-04-27
NO20051936L (no) 2005-06-23
RS20050228A (en) 2007-08-03
EP1545534B1 (en) 2007-04-18
WO2004028542A1 (en) 2004-04-08
MXPA05003161A (es) 2005-09-12
PL374696A1 (en) 2005-10-31
CN1684684A (zh) 2005-10-19
ATE359789T1 (de) 2007-05-15
RU2005112711A (ru) 2006-02-27
US20060128716A1 (en) 2006-06-15
KR20050074450A (ko) 2005-07-18
PT1545534E (pt) 2007-06-22
DE60313344D1 (de) 2007-05-31
CA2499738A1 (en) 2004-04-08
EP1545534A1 (en) 2005-06-29
ZA200502212B (en) 2006-02-22
HRP20050281A2 (en) 2006-07-31
DE60313344T2 (de) 2008-01-03
CR7754A (es) 2005-12-02
ES2285251T3 (es) 2007-11-16
ECSP055700A (es) 2005-08-11
JP2006502195A (ja) 2006-01-19
AU2003299065A1 (en) 2004-04-19
AU2003299065B2 (en) 2006-10-26
CN100372535C (zh) 2008-03-05

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012.