BR0311315A - Sulfonas aromáticas e sua utilização médica - Google Patents
Sulfonas aromáticas e sua utilização médicaInfo
- Publication number
- BR0311315A BR0311315A BR0311315-9A BR0311315A BR0311315A BR 0311315 A BR0311315 A BR 0311315A BR 0311315 A BR0311315 A BR 0311315A BR 0311315 A BR0311315 A BR 0311315A
- Authority
- BR
- Brazil
- Prior art keywords
- alkyl
- optionally substituted
- ring
- hydrogen
- integer selected
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Reproductive Health (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Child & Adolescent Psychology (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Otolaryngology (AREA)
- Gynecology & Obstetrics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
"SULFONAS AROMáTICAS E SUA UTILIZAçãO MéDICA". A invenção proporciona compostos de fórmula (I): onde A e B representam grupos -(CH~ 2~)~ m~- e -(CH~ 2~)~ n~- respectivamente; R^ 1^ representa hidrogênio ou alquila C~ 1-6~; R^ 2^ representa hidrogênio, halogênio, ciano, nitro, hidroxialquila C~ 1-6~, trifluormetila, trifluormetoxila, alquila C~ 1-6~, alcoxila C~ 1-6~, fluoralcoxila C~ 1-6~, - (CH~ 2~)~ p~cicloalquila C~ 3-6~-(CH~ 2~)~ p~Ocicloalquila C~ 3-6~, -COalquila C~ 1-6~, -SO~ 2~alquila C~ 1-6~, SOalquila C~ 1-6~, -S-alquila C~ 1-6~, -CO~ 2~alquila C~ -16~, -CO~ 2~NR^ 5^R^ 6^, SO~ 2~NR^ 5^R^ 6^, -(CH~ 2~)~ p~NR^ 5^R^ 6^, anel arila opcionalmente substituído, anel heteroarila opcionalmente substituído ou anel heterociclila opcionalmente substituído; R^ 3^ representa anel arila opcionalmente substituído ou anel heteroarila opcionalmente substituído; R^ 4^ representa hidrogênio, hidroxila, alquila C~ 1-6~, alcoxila C~ 1-6~, trifluormetila, trifluormetoxila, halogênio, -OSO~ 2~CF~ 3~, - (CH~ 2~)~ p~cicloalquila C~ 3-6~, - (CH~ 2~)~ q~Oalquila C~ 1-6~ ou (CH~ 2~)~ p~Ocicloalquila C~ 3-6~; R^ 5^ e R^ 6^ cada um independentemente representa hidrogênio, alquila C~ 1-6~ ou, juntamente com o nitrogênio ou outros átomos aos quais eles estão ligados, formam um anel azacicloalquila ou um anel azacicloalquila oxosubstituído; Z representa -(CH~ 2~)~ r~X- onde o grupo -(CH~ 2~)~ r~ está ligado a R^ 3^ ou onde X está ligado a R^ 3^ , e onde qualquer dos grupos -CH~ 2~- pode ser opcionalmente substituído por um ou mais grupos alquila C~ 1-6~; X representa oxigênio, NR^ 7^ ou -CH~ 2~ onde o grupo -CH~ 2~- pode ser opcionalmente substituído por um ou mais grupos alquila C~ 1-6~; R^ 7^ representa hidrogênio ou alquila C~ 1-6~; m e n representam independentemente um inteiro selecionado a partir de 1 e 2; p representa independentemente um inteiro selecionado a partir de 0, 1, 2 e 3; q representa independentemente um inteiro selecionado a partir de 1, 2 e 3; r representa independentemente um inteiro selecionado a partir de 0, 1, e 2; ou um seu sal farmaceuticamente aceitável ou um seu solvato. Os compostos são úteis em terapia, particularmente como agentes antipsicóticos.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0212401A GB0212401D0 (en) | 2002-05-29 | 2002-05-29 | Compounds |
| GB0230053A GB0230053D0 (en) | 2002-12-23 | 2002-12-23 | Compounds |
| PCT/EP2003/005727 WO2003099786A2 (en) | 2002-05-29 | 2003-05-28 | Aromatic sulfones and their medical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0311315A true BR0311315A (pt) | 2005-03-01 |
Family
ID=29585827
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0311315-9A BR0311315A (pt) | 2002-05-29 | 2003-05-28 | Sulfonas aromáticas e sua utilização médica |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US7504392B2 (pt) |
| EP (1) | EP1511727B1 (pt) |
| JP (1) | JP4268126B2 (pt) |
| KR (1) | KR20050013196A (pt) |
| AR (1) | AR040126A1 (pt) |
| AT (1) | ATE354566T1 (pt) |
| AU (1) | AU2003232846B9 (pt) |
| BR (1) | BR0311315A (pt) |
| CA (1) | CA2486962A1 (pt) |
| CY (1) | CY1107053T1 (pt) |
| DE (1) | DE60311986T2 (pt) |
| DK (1) | DK1511727T3 (pt) |
| ES (1) | ES2279965T3 (pt) |
| HK (1) | HK1075050A1 (pt) |
| IL (1) | IL165330A0 (pt) |
| IS (1) | IS2482B (pt) |
| MX (1) | MXPA04011945A (pt) |
| MY (1) | MY133587A (pt) |
| NO (1) | NO330118B1 (pt) |
| NZ (1) | NZ536694A (pt) |
| PL (1) | PL374081A1 (pt) |
| PT (1) | PT1511727E (pt) |
| RU (1) | RU2327690C2 (pt) |
| SI (1) | SI1511727T1 (pt) |
| TW (1) | TWI281914B (pt) |
| WO (1) | WO2003099786A2 (pt) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR040126A1 (es) | 2002-05-29 | 2005-03-16 | Glaxo Group Ltd | Compuesto de fenilsulfonilo, composicion farmaceutica que lo comprende y su uso para la elaboracion de un medicamento |
| MXPA04012704A (es) * | 2002-06-19 | 2005-03-23 | Schering Corp | Agonistas de los receptores canabinoides. |
| GB0319235D0 (en) * | 2003-08-15 | 2003-09-17 | Glaxo Group Ltd | Novel compounds |
| GB0327740D0 (en) * | 2003-11-28 | 2003-12-31 | Glaxo Group Ltd | Novel compounds |
| GB0327741D0 (en) * | 2003-11-28 | 2003-12-31 | Glaxo Group Ltd | Novel compounds |
| GB0327737D0 (en) * | 2003-11-28 | 2003-12-31 | Glaxo Group Ltd | Novel compounds |
| GB0327738D0 (en) * | 2003-11-28 | 2003-12-31 | Glaxo Group Ltd | Novel compound |
| GB0505437D0 (en) * | 2005-03-17 | 2005-04-20 | Merck Sharp & Dohme | Therapeutic agents |
| GB0505725D0 (en) * | 2005-03-19 | 2005-04-27 | Merck Sharp & Dohme | Therapeutic agents |
| EP2248527A3 (en) * | 2005-03-31 | 2013-04-03 | Amylin Pharmaceuticals, LLC | Compositions and methods for the control, prevention, and treatment of obesity and eating disorders |
| GB0510599D0 (en) * | 2005-05-24 | 2005-06-29 | Glaxo Group Ltd | Novel compounds |
| GB0603087D0 (en) * | 2006-02-15 | 2006-03-29 | Glaxo Group Ltd | Novel use |
| US20070293475A1 (en) * | 2006-06-20 | 2007-12-20 | Alcon Manufacturing Ltd. | Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma |
| AU2009313392B2 (en) * | 2008-11-06 | 2016-05-05 | Array Biopharma, Inc. | Methods of synthesis of benzazepine derivatives |
| CA2970502A1 (en) * | 2014-12-12 | 2016-06-16 | The Schepens Eye Research Institute, Inc. | Gdnf induction for the treatment of retinal disorders |
| US11124497B1 (en) | 2020-04-17 | 2021-09-21 | Pardes Biosciences, Inc. | Inhibitors of cysteine proteases and methods of use thereof |
| US11174231B1 (en) | 2020-06-09 | 2021-11-16 | Pardes Biosciences, Inc. | Inhibitors of cysteine proteases and methods of use thereof |
| US11351149B2 (en) | 2020-09-03 | 2022-06-07 | Pfizer Inc. | Nitrile-containing antiviral compounds |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01503233A (ja) | 1986-10-28 | 1989-11-02 | スミス・クライン・アンド・フレンチ・ラボラトリース・リミテッド | 製薬活性化合物 |
| DE3869446D1 (de) * | 1987-03-10 | 1992-04-30 | Lion Corp | Desodorierungsmittel. |
| EP0285287A3 (en) * | 1987-03-23 | 1990-08-16 | Smithkline Beecham Corporation | 3-benzazepine compounds for use in treating gastrointestinal motility disorders |
| GB8717374D0 (en) | 1987-07-22 | 1987-08-26 | Smith Kline French Lab | Pharmaceutically active compounds |
| US5032604A (en) | 1989-12-08 | 1991-07-16 | Merck & Co., Inc. | Class III antiarrhythmic agents |
| GB9127041D0 (en) | 1991-12-20 | 1992-02-19 | Fujisawa Pharmaceutical Co | New use |
| GB9212308D0 (en) | 1992-06-10 | 1992-07-22 | Ici Plc | Therapeutic compositions |
| CA2184101C (en) | 1994-02-25 | 2005-11-22 | Susumu Nakagawa | Carbapenem derivatives |
| US5684195A (en) * | 1994-07-14 | 1997-11-04 | G. D. Searle & Co. | Method of preparing sulfmonamides from sulfones |
| EP0828754B1 (en) | 1995-05-29 | 2005-02-02 | Pfizer Inc. | Dipeptides which promote release of growth hormone |
| DE19548785A1 (de) | 1995-12-27 | 1997-07-03 | Basf Ag | Saure Polyazofarbstoffe |
| EP0917530B1 (en) | 1996-05-11 | 2003-02-19 | SmithKline Beecham plc | Tetrahydroisoquinoline derivatives as modulators of dopamine d3 receptors |
| DE69704060T2 (de) | 1996-08-14 | 2001-08-02 | Smithkline Beecham P.L.C., Brentford | Tetrahydroisochinolinderivate und ihre pharmazeutische anwendung |
| DE19638484A1 (de) | 1996-09-20 | 1998-03-26 | Basf Ag | Hetaroylderivate |
| DE19638486A1 (de) | 1996-09-20 | 1998-03-26 | Basf Ag | Hetaroylderivate |
| WO1998047869A1 (en) | 1997-04-22 | 1998-10-29 | Cocensys, Inc. | Carbocyclic and heterocyclic substituted semicarbazones and thiosemicarbazones and the use thereof |
| GB9708805D0 (en) | 1997-05-01 | 1997-06-25 | Smithkline Beecham Plc | Compounds |
| EP0937723A1 (de) | 1998-02-18 | 1999-08-25 | Roche Diagnostics GmbH | Neue Sulfonamide, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel |
| GB9804734D0 (en) * | 1998-03-05 | 1998-04-29 | Pfizer Ltd | Compounds |
| US6344486B1 (en) | 1998-04-03 | 2002-02-05 | 3-Dimensional Pharmaceuticals, Inc. | Benzamide and sulfonamide substituted aminoguanidines and alkoxyguanidines as protease inhibitors |
| CA2346396C (en) | 1998-10-09 | 2009-04-28 | Janssen Pharmaceutica N.V. | 4,5-dihydro-isoxazole derivatives and their pharmaceutical use |
| TWI274750B (en) | 1999-01-12 | 2007-03-01 | Abbott Gmbh & Co Kg | Triazole compounds showing high affinity to dopamine D3 receptor and pharmaceutical composition comprising the same |
| KR20010102486A (ko) | 1999-03-03 | 2001-11-15 | 데이비드 엠 모이어 | 알케닐- 및 알키닐-함유 메탈로프로테아제 저해제 |
| CA2374650A1 (en) | 1999-05-24 | 2000-11-30 | Penglie Zhang | Inhibitors of factor xa |
| US6531478B2 (en) | 2000-02-24 | 2003-03-11 | Cheryl P. Kordik | Amino pyrazole derivatives useful for the treatment of obesity and other disorders |
| ES2252230T3 (es) | 2000-05-11 | 2006-05-16 | Bristol-Myers Squibb Company | Analogos de tetrahidroisoquinolina utiles como secretores de la hormona del crecimiento. |
| US6416458B1 (en) * | 2000-07-12 | 2002-07-09 | Therion Research Inc. | Therapeutic flexible magnetic sheet and method |
| WO2002021951A1 (en) | 2000-09-14 | 2002-03-21 | Edmund Gene Butts | Curling garment brush retainer |
| DE10053799A1 (de) | 2000-10-30 | 2002-05-08 | Bayer Ag | Verwendung von Tetrahydroisochinolinsulfonamiden |
| ATE382617T1 (de) | 2000-11-14 | 2008-01-15 | Smithkline Beecham Plc | Tetrahydrobenzazepin-derivate zur verwendung als dopamin-d3-rezeptor-modulatoren (antipsychotische mittel) |
| WO2002046164A1 (en) | 2000-12-07 | 2002-06-13 | Astrazeneca Ab | Therapeutic compounds |
| GB0111186D0 (en) | 2001-05-08 | 2001-06-27 | Smithkline Beecham Plc | Novel compounds |
| US20050176759A1 (en) | 2001-12-21 | 2005-08-11 | Mahmood Ahmed | 7-sulfonyl-3-benzazepine derivatives as modulators of the dopamine receptor and their use for the treatment cns disorders |
| WO2003068732A2 (en) | 2002-02-13 | 2003-08-21 | Glaxo Group Limited | Benzenesulfonamide derivatives and their use as dopamine d3 and d2 receptor liga ds |
| JP2005526724A (ja) | 2002-02-13 | 2005-09-08 | グラクソ グループ リミテッド | 抗精神病剤としてのベンゼンスルホンアミド誘導体 |
| ATE323680T1 (de) | 2002-02-13 | 2006-05-15 | Glaxo Group Ltd | 7-arylsulfonamid-2,3,4,5-tetrahydro-1h- benzo¬däazepine mit 5-ht6 rezeptor affinität zur behandlung von zentralnervensystemerkrankungen |
| GB0210762D0 (en) | 2002-05-10 | 2002-06-19 | Glaxo Group Ltd | Compounds |
| GB0212399D0 (en) | 2002-05-29 | 2002-07-10 | Glaxo Group Ltd | Compounds |
| AR040126A1 (es) | 2002-05-29 | 2005-03-16 | Glaxo Group Ltd | Compuesto de fenilsulfonilo, composicion farmaceutica que lo comprende y su uso para la elaboracion de un medicamento |
-
2003
- 2003-05-27 AR ARP030101854A patent/AR040126A1/es unknown
- 2003-05-27 TW TW092114200A patent/TWI281914B/zh not_active IP Right Cessation
- 2003-05-27 MY MYPI20031957A patent/MY133587A/en unknown
- 2003-05-28 EP EP03755153A patent/EP1511727B1/en not_active Expired - Lifetime
- 2003-05-28 WO PCT/EP2003/005727 patent/WO2003099786A2/en active IP Right Grant
- 2003-05-28 DE DE60311986T patent/DE60311986T2/de not_active Expired - Lifetime
- 2003-05-28 NZ NZ536694A patent/NZ536694A/en not_active IP Right Cessation
- 2003-05-28 IL IL16533003A patent/IL165330A0/xx not_active IP Right Cessation
- 2003-05-28 DK DK03755153T patent/DK1511727T3/da active
- 2003-05-28 KR KR10-2004-7019172A patent/KR20050013196A/ko active IP Right Grant
- 2003-05-28 SI SI200330757T patent/SI1511727T1/sl unknown
- 2003-05-28 PT PT03755153T patent/PT1511727E/pt unknown
- 2003-05-28 JP JP2004507444A patent/JP4268126B2/ja not_active Expired - Fee Related
- 2003-05-28 CA CA002486962A patent/CA2486962A1/en not_active Abandoned
- 2003-05-28 AT AT03755153T patent/ATE354566T1/de active
- 2003-05-28 RU RU2004138588/04A patent/RU2327690C2/ru not_active IP Right Cessation
- 2003-05-28 AU AU2003232846A patent/AU2003232846B9/en not_active Ceased
- 2003-05-28 PL PL03374081A patent/PL374081A1/xx not_active Application Discontinuation
- 2003-05-28 BR BR0311315-9A patent/BR0311315A/pt not_active Application Discontinuation
- 2003-05-28 US US10/515,998 patent/US7504392B2/en not_active Expired - Fee Related
- 2003-05-28 MX MXPA04011945A patent/MXPA04011945A/es active IP Right Grant
- 2003-05-28 ES ES03755153T patent/ES2279965T3/es not_active Expired - Lifetime
-
2004
- 2004-12-01 IS IS7577A patent/IS2482B/is unknown
- 2004-12-27 NO NO20045659A patent/NO330118B1/no not_active IP Right Cessation
-
2005
- 2005-08-23 HK HK05107403A patent/HK1075050A1/xx not_active IP Right Cessation
-
2007
- 2007-04-30 CY CY20071100580T patent/CY1107053T1/el unknown
-
2008
- 2008-06-24 US US12/144,917 patent/US20080269197A1/en not_active Abandoned
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0311315A (pt) | Sulfonas aromáticas e sua utilização médica | |
| BRPI0407543A (pt) | derivados de piperidina-benzenossulfonamida | |
| BR9911182A (pt) | Composto, uso do mesmo, processo para o tratamento de um mamìfero, incluindo homem, de condições suscetìveis de melhora por um agonista de beta-adrenorreceptor atìpico, composição farmacêutica, e, processo para a preparação de um composto. | |
| BR0211206A (pt) | Derivados de 8-metóxi-(1,2,4)triazolo(1, 5-a)piridina e seus usos como ligantes do receptor de adenosina | |
| BRPI0514632A (pt) | derivados de ftalazinona 4-heteroarilmetila substituìdos | |
| EA200300354A1 (ru) | Хинолиноновые производные в качестве ингибиторов тирозинкиназы | |
| BR0013792A (pt) | Derivados de amino-triazolopiridina | |
| BRPI0414450A (pt) | derivados de diazabicicloalcano substituìdos como ligandos nos receptores de alfa 7 acetilcolina nicotìnica | |
| AR036107A1 (es) | Derivados de 6-fenilpirrolpirimidindiona, antagonista de los receptores a2 de la adenosina, particularmente del subtipo a2, de aplicacion en la prevencion de la degranulacion de los mastocitos; composiciones farmaceuticas formuladas con dichos compuestos y uso de los mismos en la preparacion de medi | |
| HUP0300616A2 (hu) | Adamantánszármazékok, eljárás az előállításukra, alkalmazásuk és ezeket tartalmazó gyógyszerkészítmények | |
| FR2838439B1 (fr) | Derives de terphenyle, leur preparation, les compositions pharmaceutqiues en contenant | |
| DE60206756D1 (de) | Purin derivate als a2b adenosin rezeptor antagonisten | |
| DE60236719D1 (de) | Purinderivate als antagonisten an purinergen rezeptoren | |
| BR0011097A (pt) | Derivados de 5-fenil-piridina | |
| ATE425142T1 (de) | Inhibitoren von c-jun n-terminal kinasen (jnk) | |
| EA200400466A1 (ru) | Производные пиперазина с антагонистической активностью к рецептору ccr1 | |
| DE60212146D1 (de) | Piperidin derivate als ccr5 rezeptor antagonisten zur behandlung von hiv | |
| CY1108061T1 (el) | Παραγωγα κιναζολινης ως src αναστολεις κινασης τυροσινης | |
| MX2009009121A (es) | Aminoamidas como antagonistas de orexina. | |
| ATE374190T1 (de) | Tetrahydrochinazolinderivate als cfr-antagonisten | |
| BR0307557A (pt) | Derivados benzenosulfonamida como agentes antipsicóticos | |
| CY1112679T1 (el) | Κινολινες και θεραπευτικη χρηση αυτων | |
| DK1153017T3 (da) | Bicykliske forbindelser og deres anvendelse som integrinreceptorligander | |
| FR2847899B1 (fr) | Derives d'indole-3-carboxamide, leur preparation et leur application en therapeutique | |
| BR0011127A (pt) | Derivados de 4-fenil-pirimidina |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
| B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |