BR0309711A - Método para o tratamento de doenças do câncer - Google Patents
Método para o tratamento de doenças do câncerInfo
- Publication number
- BR0309711A BR0309711A BR0309711-0A BR0309711A BR0309711A BR 0309711 A BR0309711 A BR 0309711A BR 0309711 A BR0309711 A BR 0309711A BR 0309711 A BR0309711 A BR 0309711A
- Authority
- BR
- Brazil
- Prior art keywords
- progressing
- radiotherapy
- cancer
- treatment
- treating cancer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Silicon Polymers (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
"MéTODO PARA O TRATAMENTO DE DOENçAS DO CâNCER". A presente invenção refere-se a um método para o tratamento de um animal de sangue quente, de modo especial de um ser humano que tenha uma doença de câncer selecionada a partir de heptoma, câncer primário do tubo falopiano, câncer primário do peritónio; câncer da mama em progresso depois de tratamento com agentes hormonais ou radioterapia; carcinoma da célula renal em progresso depois do tratamento com uma citocina, radioterapia e/ou nefrectomia; melanoma em progresso depois do tratamento com radioterapia, câncer da próstata em progresso depois de orquiectomia; câncer de ovário em progresso depois do tratamento com um composto de platina ou radioterapia; e câncer de coloretal depois de radioterapia e/ou tratamento com oxaplatina ou irinotecan; e a metástase dos mesmos, que compreende a administração ao referido animal de uma quantidade terapeuticamente eficaz de um derivado da epotilona da fórmula I
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37706302P | 2002-05-01 | 2002-05-01 | |
| PCT/EP2003/004581 WO2003092683A1 (en) | 2002-05-01 | 2003-04-30 | Epothilone derivative for the treatment of hepatoma and other cancer diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0309711A true BR0309711A (pt) | 2005-02-09 |
Family
ID=29401440
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0309711-0A BR0309711A (pt) | 2002-05-01 | 2003-04-30 | Método para o tratamento de doenças do câncer |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US20050282873A1 (pt) |
| EP (1) | EP1503756B1 (pt) |
| JP (1) | JP2005528414A (pt) |
| KR (1) | KR20040106422A (pt) |
| CN (1) | CN1649585A (pt) |
| AT (1) | ATE439130T1 (pt) |
| AU (1) | AU2003227702B2 (pt) |
| BR (1) | BR0309711A (pt) |
| CA (1) | CA2483826C (pt) |
| CY (1) | CY1109607T1 (pt) |
| DE (1) | DE60328772D1 (pt) |
| DK (1) | DK1503756T3 (pt) |
| ES (1) | ES2330324T3 (pt) |
| HK (1) | HK1073601A1 (pt) |
| IL (1) | IL164783A (pt) |
| MX (1) | MXPA04010853A (pt) |
| NO (1) | NO20045249L (pt) |
| NZ (1) | NZ536178A (pt) |
| PL (1) | PL211114B1 (pt) |
| PT (1) | PT1503756E (pt) |
| RU (1) | RU2358730C2 (pt) |
| SI (1) | SI1503756T1 (pt) |
| WO (1) | WO2003092683A1 (pt) |
| ZA (1) | ZA200408492B (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0309711A (pt) * | 2002-05-01 | 2005-02-09 | Novartis Ag | Método para o tratamento de doenças do câncer |
| US20060235059A1 (en) * | 2003-09-02 | 2006-10-19 | Dilea Clifford | Cancer treatment with epothilones |
| US8394365B2 (en) * | 2003-09-17 | 2013-03-12 | Nektar Therapeutics | Multi-arm polymer prodrugs |
| EP1640004A1 (en) * | 2004-09-24 | 2006-03-29 | Schering Aktiengesellschaft | Use of epothilones in the treatment of bone metastases and bone tumors or cancers |
| EP1824458A1 (en) * | 2004-11-18 | 2007-08-29 | Bristol-Myers Squibb Company | Enteric coated bead comprising epothilone or an epothilone analog, and preparation and administration thereof |
| US20060121511A1 (en) | 2004-11-30 | 2006-06-08 | Hyerim Lee | Biomarkers and methods for determining sensitivity to microtubule-stabilizing agents |
| CA2597647A1 (en) | 2005-02-11 | 2007-08-02 | University Of Southern California | Method of expressing proteins with disulfide bridges |
| US8008256B2 (en) | 2006-05-01 | 2011-08-30 | University Of Southern California | Combination therapy for treatment of cancer |
| MX2008004268A (es) * | 2008-03-28 | 2009-09-28 | Posi Visionary Solutions Llp | Metoclopramida de liberacion prolongada de 24 horas. |
| MX2008004267A (es) * | 2008-03-28 | 2009-09-28 | Posi Visionary Solutions Llp | Metoclopramida de liberacion prolongada de 12 horas. |
| WO2010056901A2 (en) | 2008-11-13 | 2010-05-20 | University Of Southern California | Method of expressing proteins with disulfide bridges with enhanced yields and activity |
| CN101747326B (zh) * | 2010-01-12 | 2012-07-25 | 山东大学 | 18元大环内酯类埃博霉素化合物及其应用 |
| MX2012013100A (es) | 2010-05-18 | 2013-01-22 | Cerulean Pharma Inc | Composiciones y metodos para el tratamiento de enfermedades autoinmunes y otras enfermedades. |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6204388B1 (en) * | 1996-12-03 | 2001-03-20 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
| US6660758B1 (en) * | 1996-12-13 | 2003-12-09 | The Scripps Research Institute | Epothilone analogs |
| US6194181B1 (en) * | 1998-02-19 | 2001-02-27 | Novartis Ag | Fermentative preparation process for and crystal forms of cytostatics |
| US6302838B1 (en) * | 1998-02-25 | 2001-10-16 | Novartis Ag | Cancer treatment with epothilones |
| BR0008379A (pt) * | 1999-02-22 | 2002-09-24 | Biotechnolog Forschung Gmbh | Epotilonas modificadas em c-21 |
| GB9918429D0 (en) * | 1999-08-04 | 1999-10-06 | Novartis Ag | Organic compounds |
| BR0309711A (pt) * | 2002-05-01 | 2005-02-09 | Novartis Ag | Método para o tratamento de doenças do câncer |
-
2003
- 2003-04-30 BR BR0309711-0A patent/BR0309711A/pt active Search and Examination
- 2003-04-30 CA CA2483826A patent/CA2483826C/en not_active Expired - Fee Related
- 2003-04-30 WO PCT/EP2003/004581 patent/WO2003092683A1/en active IP Right Grant
- 2003-04-30 JP JP2004500867A patent/JP2005528414A/ja active Pending
- 2003-04-30 EP EP03725129A patent/EP1503756B1/en not_active Expired - Lifetime
- 2003-04-30 PT PT03725129T patent/PT1503756E/pt unknown
- 2003-04-30 MX MXPA04010853A patent/MXPA04010853A/es active IP Right Grant
- 2003-04-30 SI SI200331688T patent/SI1503756T1/sl unknown
- 2003-04-30 PL PL371727A patent/PL211114B1/pl not_active IP Right Cessation
- 2003-04-30 KR KR10-2004-7017468A patent/KR20040106422A/ko active Search and Examination
- 2003-04-30 AT AT03725129T patent/ATE439130T1/de active
- 2003-04-30 RU RU2004135307/15A patent/RU2358730C2/ru not_active IP Right Cessation
- 2003-04-30 NZ NZ536178A patent/NZ536178A/en not_active IP Right Cessation
- 2003-04-30 CN CNA038097702A patent/CN1649585A/zh active Pending
- 2003-04-30 AU AU2003227702A patent/AU2003227702B2/en not_active Ceased
- 2003-04-30 ES ES03725129T patent/ES2330324T3/es not_active Expired - Lifetime
- 2003-04-30 US US10/512,504 patent/US20050282873A1/en not_active Abandoned
- 2003-04-30 DK DK03725129T patent/DK1503756T3/da active
- 2003-04-30 DE DE60328772T patent/DE60328772D1/de not_active Expired - Lifetime
-
2004
- 2004-10-20 ZA ZA200408492A patent/ZA200408492B/en unknown
- 2004-10-21 IL IL164783A patent/IL164783A/en not_active IP Right Cessation
- 2004-11-30 NO NO20045249A patent/NO20045249L/no not_active Application Discontinuation
-
2005
- 2005-07-20 HK HK05106147.4A patent/HK1073601A1/xx not_active IP Right Cessation
-
2008
- 2008-03-11 US US12/046,017 patent/US20080161369A1/en not_active Abandoned
-
2009
- 2009-11-11 CY CY20091101180T patent/CY1109607T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2358730C2 (ru) | 2009-06-20 |
| US20080161369A1 (en) | 2008-07-03 |
| PL371727A1 (en) | 2005-06-27 |
| PT1503756E (pt) | 2009-10-28 |
| NO20045249L (no) | 2005-01-26 |
| CN1649585A (zh) | 2005-08-03 |
| ES2330324T3 (es) | 2009-12-09 |
| RU2004135307A (ru) | 2005-09-10 |
| SI1503756T1 (sl) | 2010-01-29 |
| NZ536178A (en) | 2007-10-26 |
| HK1073601A1 (en) | 2005-10-14 |
| ATE439130T1 (de) | 2009-08-15 |
| EP1503756B1 (en) | 2009-08-12 |
| US20050282873A1 (en) | 2005-12-22 |
| ZA200408492B (en) | 2006-09-27 |
| AU2003227702B2 (en) | 2007-07-26 |
| DE60328772D1 (de) | 2009-09-24 |
| JP2005528414A (ja) | 2005-09-22 |
| CA2483826A1 (en) | 2003-11-13 |
| MXPA04010853A (es) | 2005-02-14 |
| CY1109607T1 (el) | 2014-08-13 |
| IL164783A0 (en) | 2005-12-18 |
| WO2003092683A1 (en) | 2003-11-13 |
| DK1503756T3 (da) | 2009-11-16 |
| KR20040106422A (ko) | 2004-12-17 |
| EP1503756A1 (en) | 2005-02-09 |
| IL164783A (en) | 2011-08-31 |
| PL211114B1 (pl) | 2012-04-30 |
| AU2003227702A1 (en) | 2003-11-17 |
| CA2483826C (en) | 2012-04-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 12A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2308 DE 31/03/2015. |
|
| B07F | Notification of approval that there is no relation to art. 229 of lpi (pipeline patents) [chapter 7.6 patent gazette] |
Free format text: NOTIFICACAO DE NAO ANUENCIA RELACIONADA COM O ART. 229 DA LPI |