BR0215843A - Injectable depot compositions and their uses - Google Patents
Injectable depot compositions and their usesInfo
- Publication number
- BR0215843A BR0215843A BR0215843-4A BR0215843A BR0215843A BR 0215843 A BR0215843 A BR 0215843A BR 0215843 A BR0215843 A BR 0215843A BR 0215843 A BR0215843 A BR 0215843A
- Authority
- BR
- Brazil
- Prior art keywords
- compositions
- injectable depot
- aromatic
- polymer
- injectable
- Prior art date
Links
Landscapes
- Medicinal Preparation (AREA)
Abstract
"COMPOSIçõES DEPóSITOS INJETáVEIS E SEUS USOS". Composições depósitos injetáveis são providas que incluem um polímero biocompatível, que sofre bio-erosão, um solvente tendo uma miscibilidade em água de menos que ou igual a 7% em peso a 25<198>C, em uma quantidade efetiva para plastificar o polímero e formar um gel com o mesmo, um agente tixotrópico, e um agente benéfico. O solvente compreende um álcool aromático, um éster de um ácido aromático, uma cetona aromática, ou suas misturas. As composições têm comportamento de afinamento com cisalhamento substancialmente aperfeiçoado e reduzida força de injeção, tornando as composições facilmente implantadas debaixo da superfície de corpo de paciente através de injeção."INJECTABLE DEPOSIT COMPOSITIONS AND ITS USES". Injectable depot compositions are provided which include a biocompatible, bioerodible polymer, a solvent having a water miscibility of less than or equal to 7% by weight at 25 <198> C, in an amount effective to plasticize the polymer and form a gel with the same, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an aromatic acid ester, an aromatic ketone, or mixtures thereof. The compositions have substantially improved shear thinning behavior and reduced injection force, making the compositions easily implanted under the patient body surface by injection.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33988202P | 2002-07-31 | 2002-07-31 | |
PCT/US2002/036538 WO2004012703A1 (en) | 2002-07-31 | 2002-11-14 | Injectable depot compositions and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0215843A true BR0215843A (en) | 2005-06-07 |
Family
ID=34619206
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0215843-4A BR0215843A (en) | 2002-07-31 | 2002-11-14 | Injectable depot compositions and their uses |
Country Status (1)
Country | Link |
---|---|
BR (1) | BR0215843A (en) |
-
2002
- 2002-11-14 BR BR0215843-4A patent/BR0215843A/en not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A(S) 8A ANUIDADE(S). |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2108 DE 31/05/2011. |