BR0207830A - Compostos de carbamato para uso em prevenir ou tratar distúrbios de ansiedade - Google Patents
Compostos de carbamato para uso em prevenir ou tratar distúrbios de ansiedadeInfo
- Publication number
- BR0207830A BR0207830A BR0207830-9A BR0207830A BR0207830A BR 0207830 A BR0207830 A BR 0207830A BR 0207830 A BR0207830 A BR 0207830A BR 0207830 A BR0207830 A BR 0207830A
- Authority
- BR
- Brazil
- Prior art keywords
- preventing
- anxiety disorders
- formula
- group
- treating anxiety
- Prior art date
Links
- 208000019901 Anxiety disease Diseases 0.000 title abstract 3
- 150000004657 carbamic acid derivatives Chemical class 0.000 title abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Anesthesiology (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
"COMPOSTOS DE CARBAMATO PARA USO EM PREVENIR OU TRATAR DISTúRBIOS DE ANSIEDADE". A presente invenção refere-se a um método para prevenir ou tratar distúrbios de ansiedade compreendendo administrando a um sujeito em necessidade disso uma quantidade terapeuticamente eficaz de um composto selecionado a partir do grupo consistindo na Fórmula (I) e Fórmula (II): Fórmula (I); Fórmula (II); onde fenila é substituída em X com um a cinco átomos de halogênio selecionados a partir do grupo consistindo em flúor, cloro, bromo e iodo; e, R~ 1~, R~ 2~, R~ 3~, R~ 4~, R~ 5~ e R~ 6~ são independentemente selecionados a partir do grupo consistindo em hidrogênio e alquila C~ 1~-C~ 4~; onde alquila C~ 1~-C~ 4~ é optativamente substituída com fenila (onde fenila é optativamente substituída com substituintes independentemente selecionados a partir do grupo consistindo em halogênio, alquila C~ 1~-C~ 4~, alcóxi C~ 1~-C~ 4~, amino, nitro e ciano).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27168901P | 2001-02-27 | 2001-02-27 | |
| PCT/US2002/005423 WO2002067923A1 (en) | 2001-02-27 | 2002-02-21 | Carbamate compounds for use in preventing or treating anxiety disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0207830A true BR0207830A (pt) | 2004-06-22 |
Family
ID=23036639
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0207830-9A BR0207830A (pt) | 2001-02-27 | 2002-02-21 | Compostos de carbamato para uso em prevenir ou tratar distúrbios de ansiedade |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US7078436B2 (pt) |
| EP (1) | EP1399144B1 (pt) |
| JP (1) | JP2004523554A (pt) |
| KR (1) | KR20030078947A (pt) |
| CN (1) | CN1503665A (pt) |
| AT (1) | ATE324107T1 (pt) |
| AU (1) | AU2002306567B2 (pt) |
| BR (1) | BR0207830A (pt) |
| CA (1) | CA2439286A1 (pt) |
| CY (1) | CY1107468T1 (pt) |
| CZ (1) | CZ20032311A3 (pt) |
| DE (1) | DE60210960T2 (pt) |
| DK (1) | DK1399144T3 (pt) |
| ES (1) | ES2262826T3 (pt) |
| HK (1) | HK1062270A1 (pt) |
| HU (1) | HUP0303262A2 (pt) |
| IL (1) | IL157594A0 (pt) |
| MX (1) | MXPA03007720A (pt) |
| MY (1) | MY136391A (pt) |
| NO (1) | NO20033800L (pt) |
| NZ (1) | NZ546549A (pt) |
| PL (1) | PL364639A1 (pt) |
| PT (1) | PT1399144E (pt) |
| RS (1) | RS50505B (pt) |
| RU (1) | RU2292881C2 (pt) |
| WO (1) | WO2002067923A1 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1399144B1 (en) * | 2001-02-27 | 2006-04-26 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamate compounds for use in preventing or treating anxiety disorders |
| EP1850841A1 (en) * | 2005-01-20 | 2007-11-07 | Janssen Pharmaceutica N.V. | Methods for qt interval control |
| AU2006254899B2 (en) | 2005-06-08 | 2011-11-24 | Sk Biopharmaceuticals Co., Ltd. | Treatment of sleep-wake disorders |
| MX2009004552A (es) * | 2006-10-27 | 2009-11-10 | Janssen Pharmaceutica Nv | Metodos de tratamiento de trastornos de comportamiento perturbador. |
| US8263652B2 (en) | 2007-10-31 | 2012-09-11 | Sk Biopharmaceuticals Co., Ltd. | Stabilized pediatric suspension of carisbamate |
| US8609849B1 (en) | 2010-11-30 | 2013-12-17 | Fox Chase Chemical Diversity Center, Inc. | Hydroxylated sulfamides exhibiting neuroprotective action and their method of use |
| JP6200527B2 (ja) * | 2013-03-12 | 2017-09-20 | バイオ−ファーム ソリューションズ カンパニー リミテッド | 神経保護用フェニルカルバメート化合物及びこれを含む組成物 |
| CN105228604A (zh) * | 2013-03-12 | 2016-01-06 | 比皮艾思药物研发有限公司 | 用于预防或治疗小儿癫痫和癫痫相关综合征的苯基氨基甲酸酯化合物 |
| CA3016253C (en) * | 2016-02-29 | 2020-12-29 | Bio-Pharm Solutions Co., Ltd. | Sulfamate derivative compounds, processes for preparing them and their uses |
| US10195151B2 (en) | 2016-09-06 | 2019-02-05 | Jazz Pharmaceuticals International Iii Limited | Formulations of (R)-2-amino-3-phenylpropyl carbamate |
| EP3630072A4 (en) | 2017-06-02 | 2021-03-10 | Jazz Pharmaceuticals Ireland Limited | METHODS AND COMPOSITIONS FOR TREATMENT OF EXCESSIVE Drowsiness |
| US10940133B1 (en) | 2020-03-19 | 2021-03-09 | Jazz Pharmaceuticals Ireland Limited | Methods of providing solriamfetol therapy to subjects with impaired renal function |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3313692A (en) | 1958-04-21 | 1967-04-11 | Armour Pharma | Method of inducing calming and muscle relaxation with carbamates |
| US3278380A (en) | 1962-02-06 | 1966-10-11 | Armour Pharma | Methods of calming employing diphenyl hydroxy carbamate compounds |
| US3248418A (en) * | 1962-06-26 | 1966-04-26 | Charles D Bossinger | 2-hydroxy-2-phenyl alkyl carbamates |
| US3265728A (en) | 1962-07-18 | 1966-08-09 | Armour Pharma | Substituted phenethyl carbamates |
| US5698588A (en) | 1996-01-16 | 1997-12-16 | Yukong Limited | Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol |
| PT1401424E (pt) | 2001-02-27 | 2007-02-28 | Ortho Mcneil Pharm Inc | Compostos carbamato para utilização na prevenção ou tratamento de distúrbios psicóticos |
| DK1408953T3 (da) | 2001-02-27 | 2006-08-21 | Ortho Mcneil Pharm Inc | Carbamatforbindelser til anvendelse til forebyggelse eller behandling af bipolær sygdom |
| EP1399144B1 (en) * | 2001-02-27 | 2006-04-26 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamate compounds for use in preventing or treating anxiety disorders |
-
2002
- 2002-02-21 EP EP02759750A patent/EP1399144B1/en not_active Expired - Lifetime
- 2002-02-21 AU AU2002306567A patent/AU2002306567B2/en not_active Ceased
- 2002-02-21 DK DK02759750T patent/DK1399144T3/da active
- 2002-02-21 RS YUP-679/03A patent/RS50505B/sr unknown
- 2002-02-21 RU RU2003128986/14A patent/RU2292881C2/ru not_active IP Right Cessation
- 2002-02-21 HU HU0303262A patent/HUP0303262A2/hu unknown
- 2002-02-21 CA CA002439286A patent/CA2439286A1/en not_active Abandoned
- 2002-02-21 BR BR0207830-9A patent/BR0207830A/pt not_active IP Right Cessation
- 2002-02-21 ES ES02759750T patent/ES2262826T3/es not_active Expired - Lifetime
- 2002-02-21 MX MXPA03007720A patent/MXPA03007720A/es active IP Right Grant
- 2002-02-21 US US10/081,713 patent/US7078436B2/en not_active Expired - Fee Related
- 2002-02-21 CN CNA028087143A patent/CN1503665A/zh active Pending
- 2002-02-21 AT AT02759750T patent/ATE324107T1/de active
- 2002-02-21 DE DE60210960T patent/DE60210960T2/de not_active Expired - Lifetime
- 2002-02-21 JP JP2002567290A patent/JP2004523554A/ja active Pending
- 2002-02-21 NZ NZ546549A patent/NZ546549A/en not_active IP Right Cessation
- 2002-02-21 WO PCT/US2002/005423 patent/WO2002067923A1/en active IP Right Grant
- 2002-02-21 KR KR10-2003-7011293A patent/KR20030078947A/ko not_active Application Discontinuation
- 2002-02-21 CZ CZ20032311A patent/CZ20032311A3/cs unknown
- 2002-02-21 IL IL15759402A patent/IL157594A0/xx unknown
- 2002-02-21 PT PT02759750T patent/PT1399144E/pt unknown
- 2002-02-21 PL PL02364639A patent/PL364639A1/xx not_active Application Discontinuation
- 2002-02-27 MY MYPI20020693A patent/MY136391A/en unknown
-
2003
- 2003-08-26 NO NO20033800A patent/NO20033800L/no not_active Application Discontinuation
-
2004
- 2004-07-19 HK HK04105268A patent/HK1062270A1/xx not_active IP Right Cessation
-
2005
- 2005-08-01 US US11/194,251 patent/US20050267203A1/en not_active Abandoned
-
2006
- 2006-06-21 CY CY20061100843T patent/CY1107468T1/el unknown
-
2009
- 2009-06-01 US US12/475,815 patent/US20090234003A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| YU67903A (sh) | 2006-08-17 |
| HK1062270A1 (en) | 2004-10-29 |
| MY136391A (en) | 2008-09-30 |
| NO20033800D0 (no) | 2003-08-26 |
| NO20033800L (no) | 2003-09-26 |
| KR20030078947A (ko) | 2003-10-08 |
| CN1503665A (zh) | 2004-06-09 |
| DE60210960D1 (de) | 2006-06-01 |
| ATE324107T1 (de) | 2006-05-15 |
| IL157594A0 (en) | 2004-03-28 |
| RU2292881C2 (ru) | 2007-02-10 |
| RU2003128986A (ru) | 2005-03-20 |
| JP2004523554A (ja) | 2004-08-05 |
| NZ546549A (en) | 2007-11-30 |
| RS50505B (sr) | 2010-03-02 |
| CA2439286A1 (en) | 2002-09-06 |
| CY1107468T1 (el) | 2012-12-19 |
| HUP0303262A2 (hu) | 2004-01-28 |
| US20050267203A1 (en) | 2005-12-01 |
| US20090234003A1 (en) | 2009-09-17 |
| PT1399144E (pt) | 2006-07-31 |
| DE60210960T2 (de) | 2006-11-16 |
| MXPA03007720A (es) | 2004-11-12 |
| EP1399144B1 (en) | 2006-04-26 |
| WO2002067923A1 (en) | 2002-09-06 |
| US7078436B2 (en) | 2006-07-18 |
| AU2002306567B2 (en) | 2006-08-17 |
| ES2262826T3 (es) | 2006-12-01 |
| US20020143053A1 (en) | 2002-10-03 |
| DK1399144T3 (da) | 2006-07-24 |
| CZ20032311A3 (cs) | 2005-02-16 |
| PL364639A1 (en) | 2004-12-13 |
| EP1399144A1 (en) | 2004-03-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0207831A (pt) | Compostos carbamato para uso na prevenção ou tratamento de distúrbios do movimento | |
| BR0207645A (pt) | Compostos carbamato para utilização na prevenção ou tratamento de distúrbios neurodegenerativos | |
| NO20080877L (no) | Fremgangsmater for behandling av substansrelaterte forstyrrelser | |
| BR0207830A (pt) | Compostos de carbamato para uso em prevenir ou tratar distúrbios de ansiedade | |
| BR0207673A (pt) | Compostos de carbamato para o uso no tratamento de dor | |
| BR0207644A (pt) | Compostos de carbamato para uso na prevenção ou no tratamento de distúrbio bipolar | |
| BR0207832A (pt) | Compostos de carbamato para uso na prevenção ou tratamento de distúrbio bipolar | |
| BR0207829A (pt) | Composto de carbamato para uso na prevenção ou tratamento de distúrbios psicóticos | |
| BR0112713A (pt) | "compostos de carbamato para uso na prevenção ou tratamento de dor neuropática e dor associada a cefaléia em cacho e hemicrânia | |
| BRPI0516112A (pt) | métodos para neuroproteção | |
| BR0211244A (pt) | Compostos de carbamato para uso na prevenção ou tratamento de dor neuropática e dor associada com cefaléia em salvas e enxaqueca | |
| BR0211240A (pt) | Compostos de carbamato para uso na prevenção ou tratamento de dor neuropática e dor associada à cefaléia em cacho e hemicrânia | |
| MY136733A (en) | Carbamate compounds for use in preventing or treating psychotic disorders | |
| MY149385A (en) | Methods for treating substance-related disorders |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25A | Requested transfer of rights approved |
Free format text: JOHNSON & JOHNSON (US) |
|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 10A. ANUIDADE(S). |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012. |