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BG99197A - средство за лечение на катаракт и метод за получаването му - Google Patents

средство за лечение на катаракт и метод за получаването му

Info

Publication number
BG99197A
BG99197A BG99197A BG9919794A BG99197A BG 99197 A BG99197 A BG 99197A BG 99197 A BG99197 A BG 99197A BG 9919794 A BG9919794 A BG 9919794A BG 99197 A BG99197 A BG 99197A
Authority
BG
Bulgaria
Prior art keywords
cataract
treatment
methyl
preparation
relates
Prior art date
Application number
BG99197A
Other languages
English (en)
Inventor
Mitsuyoshi Azuma
Yoshimasa Abe
Shunji Sogo
Original Assignee
Senju Pharmaceutical Co.,Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co.,Ltd. filed Critical Senju Pharmaceutical Co.,Ltd.
Publication of BG99197A publication Critical patent/BG99197A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)

Abstract

Изобретението се отнася до средство, включващо (+)-(2s,3s)-3/(s)-3-метил-1-(3-метил-бутил-карбамоил)бутилка р-бамоил/-2-оксиранкарбоксилна киселина, нейните соли или нейния етилов естер. Средството подобрява пропускливостта на роговицата и се прилага под формата на капки за очи при лечение и профилактика на катаракта. Изобретението се отнася и до метод за получаването на средството и включва нагласяване на рн на водния разтворител, така че рн накрайния препарат да е между 3 и 7, преди или следсмесване на съединението с водния разтворител.
BG99197A 1992-05-20 1994-11-18 средство за лечение на катаракт и метод за получаването му BG99197A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12767292 1992-05-20
PCT/JP1993/000643 WO1993023032A1 (en) 1992-05-20 1993-05-17 Remedy for cataract and production thereof

Publications (1)

Publication Number Publication Date
BG99197A true BG99197A (bg) 1995-08-28

Family

ID=14965866

Family Applications (1)

Application Number Title Priority Date Filing Date
BG99197A BG99197A (bg) 1992-05-20 1994-11-18 средство за лечение на катаракт и метод за получаването му

Country Status (10)

Country Link
EP (1) EP0641563A4 (bg)
CN (1) CN1084061A (bg)
BG (1) BG99197A (bg)
BR (1) BR9306387A (bg)
CA (1) CA2135302A1 (bg)
HU (1) HUT71250A (bg)
MX (1) MX9302924A (bg)
PL (1) PL171704B1 (bg)
RU (1) RU94046058A (bg)
WO (1) WO1993023032A1 (bg)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001206850A (ja) 2000-01-25 2001-07-31 Kuraray Co Ltd 眼組織再生誘導剤
JPWO2003078415A1 (ja) 2002-03-15 2005-07-14 千寿製薬株式会社 環状ヘミアセタール誘導体およびその用途
WO2003082837A1 (fr) 2002-03-29 2003-10-09 Senju Pharmaceutical Co., Ltd. Derive de l'hydroxymorpholinone et ses utilisations medicales
AU2003248059A1 (en) 2002-07-22 2004-02-09 Senju Pharmaceutical Co., Ltd. NOVEL Alpha-KETOAMIDE DERIVATIVE AND USE THEREOF
EP2512492A1 (en) 2009-12-14 2012-10-24 University of Massachusetts Methods of inhibiting cataracts and presbyopia
KR102198622B1 (ko) 2013-03-14 2021-01-05 유니버시티 오브 매사추세츠 백내장 및 노안을 억제하는 방법
EA035402B1 (ru) 2015-11-13 2020-06-08 Зе Юниверсити Оф Массачусеттс Бифункциональные молекулы, содержащие полиэтиленгликоль, для подавления катаракт и пресбиопии

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55115878A (en) * 1979-02-27 1980-09-06 Taisho Pharmaceut Co Ltd Epoxysuccinic acid derivative
JPS62255423A (ja) * 1986-04-26 1987-11-07 Taisho Pharmaceut Co Ltd 急性中枢神経損傷治療剤
JP2515119B2 (ja) * 1987-04-20 1996-07-10 日本ケミフア株式会社 ピペラジン誘導体を含有する活性酸素産生抑制ならびに活性酸素除去作用を有する医薬組成物

Also Published As

Publication number Publication date
PL171704B1 (pl) 1997-06-30
EP0641563A1 (en) 1995-03-08
HUT71250A (en) 1995-11-28
RU94046058A (ru) 1996-10-20
EP0641563A4 (en) 1995-04-19
MX9302924A (es) 1993-11-01
PL306093A1 (en) 1995-02-20
WO1993023032A1 (en) 1993-11-25
BR9306387A (pt) 1998-09-15
CA2135302A1 (en) 1993-11-25
CN1084061A (zh) 1994-03-23
HU9403321D0 (en) 1995-02-28

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