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BG31497A3 - Method for obtaining of 4- amino- 5- alkyl- sulphonyl ortoanizamid - Google Patents

Method for obtaining of 4- amino- 5- alkyl- sulphonyl ortoanizamid

Info

Publication number
BG31497A3
BG31497A3 BG043588A BG4358879A BG31497A3 BG 31497 A3 BG31497 A3 BG 31497A3 BG 043588 A BG043588 A BG 043588A BG 4358879 A BG4358879 A BG 4358879A BG 31497 A3 BG31497 A3 BG 31497A3
Authority
BG
Bulgaria
Prior art keywords
amino
ortoanizamid
sulphonyl
alkyl
obtaining
Prior art date
Application number
BG043588A
Other languages
Bulgarian (bg)
English (en)
Inventor
Michel Thominet
Jacques Acher
Jean Monier
Original Assignee
Societe D'etudes Scientifiques Et Industriellesde L'ile-De-France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe D'etudes Scientifiques Et Industriellesde L'ile-De-France filed Critical Societe D'etudes Scientifiques Et Industriellesde L'ile-De-France
Publication of BG31497A3 publication Critical patent/BG31497A3/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
BG043588A 1978-01-20 1979-01-10 Method for obtaining of 4- amino- 5- alkyl- sulphonyl ortoanizamid BG31497A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7801632A FR2415099A1 (fr) 1978-01-20 1978-01-20 Nouveaux derives de 4-amino-5-alkylsulfonyl ortho-anisamides, leurs procedes de preparation et leur application comme psychotropes

Publications (1)

Publication Number Publication Date
BG31497A3 true BG31497A3 (en) 1982-01-15

Family

ID=9203689

Family Applications (2)

Application Number Title Priority Date Filing Date
BG043588A BG31497A3 (en) 1978-01-20 1979-01-10 Method for obtaining of 4- amino- 5- alkyl- sulphonyl ortoanizamid
BG042018A BG31496A3 (en) 1978-01-20 1979-01-10 Method for obtaining of 4- amino- 5- alkyl- sulphonyl ortoanizamid

Family Applications After (1)

Application Number Title Priority Date Filing Date
BG042018A BG31496A3 (en) 1978-01-20 1979-01-10 Method for obtaining of 4- amino- 5- alkyl- sulphonyl ortoanizamid

Country Status (42)

Country Link
US (2) US4294828A (fr)
JP (1) JPS6049192B2 (fr)
AR (2) AR221354A1 (fr)
AT (1) AT377977B (fr)
AU (1) AU528561B2 (fr)
BE (1) BE872585A (fr)
BG (2) BG31497A3 (fr)
CA (1) CA1101430A (fr)
CH (1) CH637927A5 (fr)
CS (1) CS226181B2 (fr)
CY (1) CY1201A (fr)
DD (1) DD141520A5 (fr)
DE (1) DE2901181C2 (fr)
DK (1) DK158346C (fr)
EG (1) EG14045A (fr)
ES (2) ES476755A1 (fr)
FI (1) FI71126C (fr)
FR (1) FR2415099A1 (fr)
GB (2) GB2083458B (fr)
GR (1) GR64431B (fr)
HK (1) HK12184A (fr)
HU (1) HU179793B (fr)
IE (1) IE47798B1 (fr)
IL (1) IL56411A (fr)
IN (1) IN150226B (fr)
IT (1) IT1164655B (fr)
LU (1) LU80786A1 (fr)
MC (1) MC1232A1 (fr)
MX (2) MX5793E (fr)
NL (1) NL191707C (fr)
NO (1) NO151320C (fr)
NZ (1) NZ189378A (fr)
OA (1) OA06156A (fr)
PH (2) PH15725A (fr)
PL (2) PL118151B1 (fr)
PT (1) PT69068A (fr)
RO (2) RO76393A (fr)
SE (2) SE448874B (fr)
SU (1) SU820659A3 (fr)
YU (2) YU42172B (fr)
ZA (1) ZA79219B (fr)
ZM (1) ZM579A1 (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
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FR2440946A2 (fr) * 1978-01-20 1980-06-06 Ile De France Nouveaux benzamides heterocycliques substitues, leurs procedes de preparation et leur application comme modificateurs du comportement
ZA818221B (en) * 1980-12-12 1982-10-27 Beecham Group Plc Pharmaceutical compounds
FR2550447B1 (fr) * 1983-08-10 1986-01-17 Ile De France Application du n-(ally-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide comme antiagregant plaquettaire
FR2574795B1 (fr) * 1984-12-18 1987-11-20 Ile De France Nouveau procede industriel de synthese du n-((1'-allyl 2'-pyrrolidinyl) methyl) 2-methoxy 4,5-azimido benzamide
FR2584401B1 (fr) * 1985-07-04 1987-11-20 Ile De France Nouveau benzamide, son procede de preparation et son application dans le domaine therapeutique
US5227388A (en) * 1989-12-26 1993-07-13 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
US5260319A (en) * 1989-12-26 1993-11-09 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
FR2678266A1 (fr) * 1991-06-28 1992-12-31 Delagrange Laboratoires Nouveaux derives de 2-hydroxy 4-amino 5-ethylsulfonyl benzamide utiles comme anxiolytiques.
FR2699533A1 (fr) * 1992-12-21 1994-06-24 Mouhtaram Mohamed Dérivés de N-((1,4-dialkyl-6-arylpipérazine-2-yl)méthyl)benzamides. (Isomères cis et trans) Propriétés pharmacologiques et applications.
FR2753376B1 (fr) * 1996-09-18 1998-10-16 Synthelabo Compositions pharmaceutiques comprenant de l'amisulpride et leurs applications therapeutiques
FR2762213B1 (fr) * 1997-04-18 1999-05-14 Synthelabo Composition pharmaceutique a retention gastrique
US6169094B1 (en) 1998-07-14 2001-01-02 Sanofi-Synthelabo Compositions of (S) (-)-amisulpride
EP1554572B1 (fr) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions et procedes de modulation du transport a travers la barriere hematho-encephalique
WO2004100992A2 (fr) * 2003-05-16 2004-11-25 Pfizer Products Inc. Combinaisons therapeutiques d'antipsychotiques atypiques avec des modulateurs de l'acide 4-aminobutanoique et/ou des medicaments anticonvulsivants
FR2857263B1 (fr) * 2003-07-09 2005-09-09 Sanofi Synthelabo Nouvelle composition pharmaceutique solide comprenant de l'amisulpride
CA2565996A1 (fr) * 2004-05-11 2005-11-17 Pfizer Products Inc. Combinaison d'antipsychotiques atypiques et d'antagonistes du recepteur de 5-ht<sb>1b</sb>
WO2006116221A2 (fr) * 2005-04-22 2006-11-02 Wyeth Nouvelles combinaisons therapeutiques pour le traitement ou la prevention de troubles psychotiques
CA2608144C (fr) 2005-04-28 2012-11-13 Proteus Biomedical, Inc. Systeme pharma-informatique
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(rap)-접합체 투여에 의한 간 질환의 치료
US7825156B2 (en) * 2007-02-02 2010-11-02 Copharms Method of treating bipolar depression with a benzamide derivative
JP2011526881A (ja) * 2008-06-25 2011-10-20 ファイザー・インク ジアリール化合物およびそれらの使用
US20100105755A1 (en) * 2008-09-12 2010-04-29 Auspex Pharmaceuticals, Inc. Substituted benzamide modulators of dopamine receptor
ES2728225T3 (es) 2009-02-20 2019-10-23 2 Bbb Medicines B V Sistema de administración de fármacos a base de glutatión
CA2760945A1 (fr) 2009-05-06 2010-11-11 Laboratory Skin Care, Inc. Compositions pour liberation dermique comprenant des complexes principe actif-particule de phosphate de calcium et procedes d'utilisation associes
CN101898991B (zh) * 2009-05-31 2013-09-25 江苏天士力帝益药业有限公司 一种(s)(-)-氨磺必利d-(-)-酒石酸盐的合成方法
CN101628886B (zh) * 2009-08-25 2012-12-12 北京紫萌同达科技有限公司 一种2-甲氧基-4-氨基-5-乙砜基苯甲酸的合成方法
AU2014202535B2 (en) * 2010-03-11 2016-05-26 Acacia Pharma Limited The use of amisulpride as an anti-emetic
GB201004020D0 (en) 2010-03-11 2010-04-21 Acacia Pharma Ltd New therapeutic use
AU2016216578B2 (en) * 2010-03-11 2017-11-23 Acacia Pharma Limited The use of amisulpride as an anti-emetic
BR112012031959A2 (pt) 2010-06-17 2015-09-22 Lupin Ltd um processo aperfeiçoado para preparação de amisulpride
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN103319384A (zh) * 2013-06-18 2013-09-25 苏州诚和医药化学有限公司 制备2-甲氧基-4-氨基-5-乙砜基苯甲酸的方法
CN103304453A (zh) * 2013-06-18 2013-09-18 苏州诚和医药化学有限公司 两步法合成2-甲氧基-4-氨基-5-乙砜基苯甲酸
CN103450058B (zh) * 2013-09-18 2015-10-14 广安凯特医药化工有限公司 一种氨磺必利酸的制备方法
CN104725292B (zh) * 2015-03-23 2017-07-25 湖北荆江源制药股份有限公司 一种(s)(‑)‑氨磺必利的制备方法
GB201618425D0 (en) * 2016-11-01 2016-12-14 Acacia Pharma Ltd method
US11377421B2 (en) 2016-11-28 2022-07-05 Lb Pharmaceuticals Inc. Psychotropic agents and uses thereof
WO2018098497A1 (fr) 2016-11-28 2018-05-31 Lb Pharmaceuticals Inc. Agents psychotropes et leurs utilisations
CN106995397B (zh) * 2016-12-12 2020-01-14 河北医科大学 R-氨磺必利药用盐、制备方法、晶型及其用途
GB201702250D0 (en) 2017-02-10 2017-03-29 Acacia Pharma Ltd Method
JP2021505595A (ja) 2017-12-05 2021-02-18 サノビオン ファーマシューティカルズ インクSunovion Pharmaceuticals Inc. 結晶形およびその製造方法
SG11202005016SA (en) 2017-12-05 2020-06-29 Sunovion Pharmaceuticals Inc Nonracemic mixtures and uses thereof
CN110790693A (zh) * 2018-08-02 2020-02-14 北京万全德众医药生物技术有限公司 一种(s)(-)-氨磺必利的制备方法
US11160758B2 (en) 2019-06-04 2021-11-02 Sunovion Pharmaceuticals Inc. Modified release formulations and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
FR2313935A1 (fr) * 1975-06-10 1977-01-07 Ile De France Nouveaux benzamides substitues, leurs derives et leur procede de preparation
US3862139A (en) * 1972-06-23 1975-01-21 Delmar Chem Heterocyclic benzamide compounds
FR2244760B1 (fr) * 1973-09-25 1980-06-27 Ile De France
FR2299862B1 (fr) * 1975-02-07 1978-07-21 Ile De France Nouveau
FR2294698A1 (fr) * 1974-12-18 1976-07-16 Synthelabo Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment
DE2556457C3 (de) * 1974-12-18 1981-02-12 Synthelabo S.A., Paris N-(Pyrrolidin-2-yl-methyl)-2-methoxybenzamide, deren Salze, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
IE790092L (en) 1979-07-20
SE8603773D0 (sv) 1986-09-09
SE7900380L (sv) 1979-07-21
AR221354A1 (es) 1981-01-30
PL116532B1 (en) 1981-06-30
YU42172B (en) 1988-06-30
IL56411A (en) 1982-09-30
GB2012765A (en) 1979-08-01
EG14045A (en) 1983-09-30
MC1232A1 (fr) 1979-10-26
IE47798B1 (en) 1984-06-27
DE2901181C2 (de) 1984-07-19
JPS6049192B2 (ja) 1985-10-31
NZ189378A (en) 1983-03-15
NL191707C (nl) 1996-04-02
FR2415099A1 (fr) 1979-08-17
DK20979A (da) 1979-07-21
US4294828A (en) 1981-10-13
RO80311A (fr) 1982-12-06
BE872585A (fr) 1979-06-07
CH637927A5 (fr) 1983-08-31
LU80786A1 (fr) 1979-09-07
MX5793E (es) 1984-07-19
GB2083458B (en) 1983-03-09
CY1201A (en) 1983-12-31
OA06156A (fr) 1981-06-30
DE2901181A1 (de) 1979-07-26
PL118151B1 (en) 1981-09-30
IT1164655B (it) 1987-04-15
YU25483A (en) 1983-10-31
CA1101430A (fr) 1981-05-19
GR64431B (en) 1980-03-21
ES477782A1 (es) 1979-09-16
BG31496A3 (en) 1982-01-15
GB2012765B (en) 1982-09-08
AU4337379A (en) 1979-07-26
SE460968B (sv) 1989-12-11
DK158346B (da) 1990-05-07
FI71126C (fi) 1986-11-24
PT69068A (fr) 1979-02-01
YU5079A (en) 1983-06-30
ATA39879A (de) 1983-12-15
ZA79219B (en) 1980-01-30
NO151320C (no) 1985-04-17
IN150226B (fr) 1982-08-21
ZM579A1 (en) 1979-12-21
MX7623E (es) 1990-03-27
AT377977B (de) 1985-05-28
HK12184A (en) 1984-02-24
AU528561B2 (en) 1983-05-05
NO151320B (no) 1984-12-10
IT7947706A0 (it) 1979-01-18
PH15725A (en) 1983-03-18
IL56411A0 (en) 1979-03-12
JPS54145658A (en) 1979-11-14
SU820659A3 (ru) 1981-04-07
PH22287A (en) 1988-07-22
SE448874B (sv) 1987-03-23
NL7900457A (nl) 1979-07-24
FI71126B (fi) 1986-08-14
FI790182A (fi) 1979-07-21
DD141520A5 (de) 1980-05-07
SE8603773L (sv) 1986-09-09
HU179793B (en) 1982-12-28
YU41278B (en) 1986-12-31
NL191707B (nl) 1995-12-01
US4401822A (en) 1983-08-30
NO790180L (no) 1979-07-23
DK158346C (da) 1990-10-08
GB2083458A (en) 1982-03-24
CS226181B2 (en) 1984-03-19
FR2415099B1 (fr) 1981-02-20
AR220574A1 (es) 1980-11-14
ES476755A1 (es) 1979-06-01
RO76393A (fr) 1981-03-30
PL212899A1 (fr) 1980-01-14

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