BG27901A3 - Метод за получаване на n-(метокси-метил-фурил-метил)-6-7-бензоморфани и бензоморфинапи - Google Patents

Метод за получаване на n-(метокси-метил-фурил-метил)-6-7-бензоморфани и бензоморфинапи

Info

Publication number: BG27901A3
Authority: BG; Bulgaria
Prior art keywords: methyl; benzomorphanes; benzomorphinapes; furyl; methoxy
Prior art date: 1973-10-27

Application number

BG028036A

Other languages

Bulgarian (bg)

English (en)

Inventor

Herbert Merz

Adolf Langbein

Gerhard Walther

Klaus Stockhaus

Original Assignee

C.H.Boehringer Sohn

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-10-27

Filing date

1974-10-25

Publication date

1980-01-15

1974-10-25 Application filed by C.H.Boehringer Sohn filed Critical C.H.Boehringer Sohn

1980-01-15 Publication of BG27901A3 publication Critical patent/BG27901A3/xx

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

BG028036A 1973-10-27 1974-10-25 Метод за получаване на n-(метокси-метил-фурил-метил)-6-7-бензоморфани и бензоморфинапи BG27901A3 (bg)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19732354002 DE2354002A1 (de)	1973-10-27	1973-10-27	Neue n-(methoxymethyl-furylmethyl)6,7-benzomorphane und -morphinane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Publications (1)

Publication Number	Publication Date
BG27901A3 true BG27901A3 (bg)	1980-01-15

Family

ID=5896658

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
BG028037A BG27902A3 (en)	1973-10-27	1974-10-25	Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes
BG028038A BG27903A3 (en)	1973-10-27	1974-10-25	Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes and their addition salts with acid
BG028036A BG27901A3 (bg)	1973-10-27	1974-10-25	Метод за получаване на n-(метокси-метил-фурил-метил)-6-7-бензоморфани и бензоморфинапи

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
BG028037A BG27902A3 (en)	1973-10-27	1974-10-25	Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes
BG028038A BG27903A3 (en)	1973-10-27	1974-10-25	Method of obtaining of n-(methoxy-methyl-furilmethil)-6,7- benzomorphanes and-morphinanes and their addition salts with acid

Country Status (27)

Country	Link
US (1)	US3981874A (xx)
JP (1)	JPS5738590B2 (xx)
AT (6)	AT335631B (xx)
BE (1)	BE821505A (xx)
BG (3)	BG27902A3 (xx)
CA (1)	CA1056377A (xx)
CH (6)	CH609340A5 (xx)
CS (3)	CS171195B2 (xx)
DD (1)	DD115909A5 (xx)
DE (1)	DE2354002A1 (xx)
DK (1)	DK138325C (xx)
ES (6)	ES431058A1 (xx)
FI (1)	FI62079C (xx)
FR (1)	FR2248838B1 (xx)
GB (1)	GB1482552A (xx)
HU (1)	HU176479B (xx)
IE (1)	IE41528B1 (xx)
IL (1)	IL45938A (xx)
NL (1)	NL7413980A (xx)
NO (1)	NO140859C (xx)
PH (1)	PH11894A (xx)
PL (3)	PL92052B1 (xx)
RO (5)	RO65656A (xx)
SE (1)	SE422791B (xx)
SU (6)	SU511005A3 (xx)
YU (5)	YU36949B (xx)
ZA (1)	ZA746790B (xx)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1513961A (en) *	1975-02-25	1978-06-14	Acf Chemiefarma Nv	6,7-benzomorphans method for their preparation and intermediates
US4208523A (en) *	1978-11-30	1980-06-17	Sterling Drug Inc.	11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines
JP5470557B2 (ja)	2007-07-26	2014-04-16	ヴァイティーファーマシューティカルズ，インコーポレイテッド	１１β−ヒドロキシステロイドデヒドロゲナーゼ１型の阻害剤の合成
CA2704628C (en)	2007-11-16	2016-11-29	Boehringer Ingelheim International Gmbh	Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
JP5490014B2 (ja)	2007-12-11	2014-05-14	ヴァイティーファーマシューティカルズ，インコーポレイテッド	１１β−ヒドロキシステロイドデヒドロゲナーゼ１型の環状尿素阻害剤
TW200934490A (en)	2008-01-07	2009-08-16	Vitae Pharmaceuticals Inc	Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
EP2252601B1 (en)	2008-01-24	2012-12-19	Vitae Pharmaceuticals, Inc.	Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2245014B1 (en) *	2008-02-12	2011-11-02	Boehringer Ingelheim International GmbH	Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
WO2009102460A2 (en)	2008-02-15	2009-08-20	Vitae Pharmaceuticals, Inc.	Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CA2723034A1 (en)	2008-05-01	2009-11-05	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
NZ588954A (en)	2008-05-01	2012-08-31	Vitae Pharmaceuticals Inc	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2009134392A1 (en)	2008-05-01	2009-11-05	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW200950780A (en)	2008-05-13	2009-12-16	Boehringer Ingelheim Int	Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
US8846668B2 (en)	2008-07-25	2014-09-30	Vitae Pharmaceuticals, Inc.	Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CN104327062A (zh)	2008-07-25	2015-02-04	贝林格尔·英格海姆国际有限公司	11β-羟基类固醇脱氢酶1的环状抑制剂
MA33216B1 (fr)	2009-04-30	2012-04-02	Boehringer Ingelheim Int	Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
WO2011011123A1 (en)	2009-06-11	2011-01-27	Vitae Pharmaceuticals, Inc.	Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1 based on the 1,3 -oxazinan- 2 -one structure
AR078887A1 (es)	2009-11-06	2011-12-07	Boehringer Ingelheim Int	Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
US8933072B2 (en)	2010-06-16	2015-01-13	Vitae Pharmaceuticals, Inc.	Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh)	2010-11-05	2016-06-11	百靈佳殷格翰國際股份有限公司	六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
US8735585B2 (en)	2011-08-17	2014-05-27	Boehringer Ingelheim International Gmbh	Indenopyridine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3632591A (en) *	1968-07-19	1972-01-04	Sterling Drug Inc	1 2 3 4 5 6 - hexahydro-3-(cycloaliphatic or cycloaliphatic 11-dimethyl-2 alkyl)-66-methano-3-benzazocines
US3833595A (en) *	1968-12-26	1974-09-03	Sumitomo Chemical Co	2-aroylalkyl benzomorphans
CS166804B2 (xx) *	1971-02-08	1976-03-29	Boehringer Sohn Ingelheim

1973
- 1973-10-25 SU SU2069691A patent/SU511005A3/ru active
- 1973-10-25 SU SU2069684A patent/SU510999A3/ru active
- 1973-10-27 DE DE19732354002 patent/DE2354002A1/de not_active Withdrawn
1974
- 1974-01-25 RO RO7480315A patent/RO65656A/ro unknown
- 1974-10-02 CS CS6768A patent/CS171195B2/cs unknown
- 1974-10-02 CS CS6769A patent/CS171196B2/cs unknown
- 1974-10-02 CS CS6767A patent/CS171194B2/cs unknown
- 1974-10-15 US US05/514,474 patent/US3981874A/en not_active Expired - Lifetime
- 1974-10-16 AT AT828574A patent/AT335631B/de not_active IP Right Cessation
- 1974-10-16 AT AT828974A patent/AT336202B/de not_active IP Right Cessation
- 1974-10-16 ES ES431058A patent/ES431058A1/es not_active Expired
- 1974-10-16 ES ES431057A patent/ES431057A1/es not_active Expired
- 1974-10-16 AT AT829074A patent/AT335634B/de not_active IP Right Cessation
- 1974-10-16 AT AT828674A patent/AT335632B/de not_active IP Right Cessation
- 1974-10-16 ES ES431054A patent/ES431054A1/es not_active Expired
- 1974-10-16 ES ES431056A patent/ES431056A1/es not_active Expired
- 1974-10-16 ES ES431059A patent/ES431059A1/es not_active Expired
- 1974-10-16 AT AT828874A patent/AT335076B/de active
- 1974-10-16 ES ES431055A patent/ES431055A1/es not_active Expired
- 1974-10-16 AT AT828774A patent/AT335633B/de not_active IP Right Cessation
- 1974-10-24 CH CH1426574A patent/CH609340A5/xx not_active IP Right Cessation
- 1974-10-24 YU YU2854/74A patent/YU36949B/xx unknown
- 1974-10-24 YU YU2856/74A patent/YU36950B/xx unknown
- 1974-10-24 CH CH1426474A patent/CH609048A5/xx not_active IP Right Cessation
- 1974-10-24 PH PH16448A patent/PH11894A/en unknown
- 1974-10-24 CH CH1426374A patent/CH609047A5/xx not_active IP Right Cessation
- 1974-10-24 CH CH1426274A patent/CH609046A5/xx not_active IP Right Cessation
- 1974-10-24 YU YU2851/74A patent/YU36951B/xx unknown
- 1974-10-24 YU YU02852/74A patent/YU36519B/xx unknown
- 1974-10-24 YU YU2853/74A patent/YU36952B/xx unknown
- 1974-10-25 GB GB46323/74A patent/GB1482552A/en not_active Expired
- 1974-10-25 SU SU2069689A patent/SU508192A3/ru active
- 1974-10-25 IE IE2206/74A patent/IE41528B1/en unknown
- 1974-10-25 IL IL45938A patent/IL45938A/en unknown
- 1974-10-25 HU HU74BO1521A patent/HU176479B/hu unknown
- 1974-10-25 NO NO743845A patent/NO140859C/no unknown
- 1974-10-25 SE SE7413485A patent/SE422791B/xx unknown
- 1974-10-25 RO RO7480314A patent/RO65655A/ro unknown
- 1974-10-25 BG BG028037A patent/BG27902A3/xx unknown
- 1974-10-25 SU SU2070657A patent/SU508193A3/ru active
- 1974-10-25 DD DD181929A patent/DD115909A5/xx unknown
- 1974-10-25 NL NL7413980A patent/NL7413980A/xx unknown
- 1974-10-25 FR FR7435890A patent/FR2248838B1/fr not_active Expired
- 1974-10-25 RO RO7480316A patent/RO65657A/ro unknown
- 1974-10-25 FI FI3141/74A patent/FI62079C/fi active
- 1974-10-25 SU SU2070713A patent/SU512707A3/ru active
- 1974-10-25 BE BE149902A patent/BE821505A/xx not_active IP Right Cessation
- 1974-10-25 CH CH1437074A patent/CH609686A5/xx not_active IP Right Cessation
- 1974-10-25 CH CH1436974A patent/CH609685A5/xx not_active IP Right Cessation
- 1974-10-25 BG BG028038A patent/BG27903A3/xx unknown
- 1974-10-25 RO RO7480318A patent/RO65659A/ro unknown
- 1974-10-25 DK DK559874A patent/DK138325C/da not_active IP Right Cessation
- 1974-10-25 CA CA212,340A patent/CA1056377A/en not_active Expired
- 1974-10-25 JP JP12261074A patent/JPS5738590B2/ja not_active Expired
- 1974-10-25 ZA ZA00746790A patent/ZA746790B/xx unknown
- 1974-10-25 BG BG028036A patent/BG27901A3/xx unknown
- 1974-10-25 RO RO7480317A patent/RO65658A/ro unknown
- 1974-10-25 SU SU7402069685A patent/SU578870A3/ru active
- 1974-10-26 PL PL1974175143A patent/PL92052B1/pl unknown
- 1974-10-26 PL PL1974175142A patent/PL92053B1/pl unknown
- 1974-10-26 PL PL1974175144A patent/PL92086B1/pl unknown

Also Published As

Publication number	Publication date
ES431059A1 (es)	1976-10-16
FI62079B (fi)	1982-07-30
GB1482552A (en)	1977-08-10
ES431054A1 (es)	1976-10-16
ES431056A1 (es)	1976-10-16
SU510999A3 (ru)	1976-04-15
SU511005A3 (ru)	1976-04-15
FI314174A (xx)	1975-04-28
ZA746790B (en)	1976-06-30
SU512707A3 (ru)	1976-04-30
IE41528L (en)	1975-04-27
YU285674A (en)	1982-06-18
SU508193A3 (ru)	1976-03-25
RO65658A (fr)	1979-07-15
FR2248838A1 (xx)	1975-05-23
ATA829074A (de)	1976-07-15
SE422791B (sv)	1982-03-29
YU36952B (en)	1984-08-31
RO65655A (ro)	1980-06-15
IL45938A0 (en)	1974-12-31
CH609048A5 (xx)	1979-02-15
CH609686A5 (xx)	1979-03-15
US3981874A (en)	1976-09-21
CH609340A5 (xx)	1979-02-28
SU578870A3 (ru)	1977-10-30
FR2248838B1 (xx)	1977-11-04
ES431055A1 (es)	1976-10-16
NO140859B (no)	1979-08-20
SU508192A3 (ru)	1976-03-25
DD115909A5 (xx)	1975-10-20
CS171196B2 (xx)	1976-10-29
ATA828574A (de)	1976-07-15
ES431058A1 (es)	1976-10-16
DK559874A (xx)	1975-06-23
YU285274A (en)	1982-02-25
BG27903A3 (en)	1980-01-15
PH11894A (en)	1978-08-29
AT335631B (de)	1977-03-25
BG27902A3 (en)	1980-01-15
YU285374A (en)	1982-06-18
AT335633B (de)	1977-03-25
PL92053B1 (xx)	1977-03-31
ATA828674A (de)	1976-07-15
JPS5738590B2 (xx)	1982-08-16
CH609046A5 (xx)	1979-02-15
NL7413980A (nl)	1975-04-29
HU176479B (en)	1981-03-28
YU36951B (en)	1984-08-31
CS171194B2 (xx)	1976-10-29
BE821505A (fr)	1975-04-25
PL92052B1 (xx)	1977-03-31
NO140859C (no)	1979-11-28
RO65656A (ro)	1980-06-15
PL92086B1 (xx)	1977-03-31
CA1056377A (en)	1979-06-12
IE41528B1 (en)	1980-01-30
IL45938A (en)	1977-12-30
YU285474A (en)	1982-06-18
AT335632B (de)	1977-03-25
ATA828774A (de)	1976-07-15
CS171195B2 (xx)	1976-10-29
ATA828874A (de)	1976-06-15
YU36519B (en)	1984-02-29
DE2354002A1 (de)	1975-05-07
YU36949B (en)	1984-08-31
FI62079C (fi)	1982-11-10
RO65657A (ro)	1980-06-15
YU36950B (en)	1984-08-31
JPS5071679A (xx)	1975-06-13
YU285174A (en)	1982-06-18
DK138325B (da)	1978-08-14
ATA828974A (de)	1976-08-15
CH609685A5 (xx)	1979-03-15
ES431057A1 (es)	1976-10-16
NO743845L (xx)	1975-05-26
AT336202B (de)	1977-04-25
SE7413485L (xx)	1975-04-28
RO65659A (ro)	1980-06-15
AT335076B (de)	1977-02-25
CH609047A5 (xx)	1979-02-15
DK138325C (da)	1979-01-22
AT335634B (de)	1977-03-25

Publication	Publication Date	Title
BG28065A4 (en)	1980-02-25	Method of obtaining of 2-phenyl-3-aroylbenzothiophenes
BG27901A3 (bg)	1980-01-15	Метод за получаване на n-(метокси-метил-фурил-метил)-6-7-бензоморфани и бензоморфинапи
BG31499A3 (en)	1982-01-15	Method for obtaining of 1- vinyl- triazol derivatives
BG35189A3 (en)	1984-02-15	Method for preparing derivatives of 6- beta- hydroxyalkylpenicillanic acid
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BG32717A3 (en)	1982-09-15	Method for obtaining of n- organo- n- phosphonomethylglicine- n- oxides
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BG31949A3 (en)	1982-04-15	Method for obtaining derivatives of phenyl- 2- indol
BG32269A3 (en)	1982-06-15	Method for obtaining derivatives of thiazolidine- (thazin-) carbonic acides
BG27898A3 (en)	1980-01-15	Method of obtaining of 2-filamine-2-imidazoline derivatives and their salts
BG29573A3 (en)	1980-12-12	Method of obtaining of benzodiazepin derivatives
BG28072A4 (en)	1980-02-25	Method of obtaining of 1-substitvated canamyzine derivatives
BG33275A3 (en)	1983-01-14	Method for obtaining the benzophenon derivatives
BG31073A3 (en)	1981-10-15	Method for obtaining of 1, 5- substituated- 2- pyrolidine
BG29572A3 (en)	1980-12-12	Method for obtaining of pyrazol salts
BG31503A3 (en)	1982-01-15	Method for obtaining the derivatives of octahjdroindolhinolzine
BG30475A3 (en)	1981-06-15	Method for obtaining of deposteroid esters
BG35466A3 (en)	1984-04-15	Method for preparing derivatives of clavulanic acid
BG28565A3 (bg)	1980-05-15	Метод за получаване на пиролхиноксалинони и пиролбензодиазепинони
BG30021A3 (en)	1981-03-16	Method for obtaining of imidazoisohinolin- dion
BG32117A4 (en)	1982-05-14	Method for obtaining of oleandomicine
BG28043A3 (en)	1980-02-25	Method for obtatning of amine derivatives
BG30776A3 (en)	1981-08-14	Method for obtaining of eburnamenine derivatives
BG35032A3 (en)	1984-01-16	Method for preparing 1, 1, 2- triphenylpropene derivatives