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BG102864A - Application of phosphonic acid esters for the treatment of functional disorders of the brain and depressions - Google Patents

Application of phosphonic acid esters for the treatment of functional disorders of the brain and depressions

Info

Publication number
BG102864A
BG102864A BG102864A BG10286498A BG102864A BG 102864 A BG102864 A BG 102864A BG 102864 A BG102864 A BG 102864A BG 10286498 A BG10286498 A BG 10286498A BG 102864 A BG102864 A BG 102864A
Authority
BG
Bulgaria
Prior art keywords
depressions
treatment
application
brain
acid esters
Prior art date
Application number
BG102864A
Other languages
Bulgarian (bg)
Inventor
Fritz Maurer
Bernard Schmidt
Stephan Lensky
Der Staay Franz-Josef Van
Richard FANELLI
David BRITELLI
Original Assignee
Bayer Aktiengesellschaft
Troponwerke Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Aktiengesellschaft, Troponwerke Gmbh & Co. Kg filed Critical Bayer Aktiengesellschaft
Publication of BG102864A publication Critical patent/BG102864A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to the application of esters of thephosphonic acid for the treatment and prevention of functionalbrain disorders, in particular of Altzheimer's type of dimentia,and of depressions, to new compounds and to their preparation.12 claims
BG102864A 1996-04-25 1998-10-22 Application of phosphonic acid esters for the treatment of functional disorders of the brain and depressions BG102864A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19616471A DE19616471A1 (en) 1996-04-25 1996-04-25 Phosphonic acid ester for the treatment of brain disorders and depression
PCT/US1997/006469 WO1997039756A1 (en) 1996-04-25 1997-04-17 Use of phosphonic acid esters for the treatment of functional disorders of the brain and depression

Publications (1)

Publication Number Publication Date
BG102864A true BG102864A (en) 1999-09-30

Family

ID=7792381

Family Applications (1)

Application Number Title Priority Date Filing Date
BG102864A BG102864A (en) 1996-04-25 1998-10-22 Application of phosphonic acid esters for the treatment of functional disorders of the brain and depressions

Country Status (19)

Country Link
EP (1) EP0896540A1 (en)
JP (1) JP2000510455A (en)
KR (1) KR20000010611A (en)
AR (1) AR006870A1 (en)
AU (1) AU2462397A (en)
BG (1) BG102864A (en)
BR (1) BR9709300A (en)
CA (1) CA2252567A1 (en)
CZ (1) CZ343498A3 (en)
DE (1) DE19616471A1 (en)
HU (1) HUP9903366A3 (en)
ID (1) ID16678A (en)
IL (1) IL126698A0 (en)
NO (1) NO984964L (en)
PL (1) PL333464A1 (en)
SK (1) SK146398A3 (en)
TR (1) TR199802137T2 (en)
WO (1) WO1997039756A1 (en)
ZA (1) ZA973538B (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1078370B (en) * 1958-09-16 1960-03-24 Norddeutsche Affinerie Pest repellants
US3069312A (en) * 1960-09-28 1962-12-18 California Research Corp N-substituted dimethyl 1-carbamoyloxy-2, 2, 2-trichloroethyl phosphonates as insecticidal compositions
BE632366A (en) * 1962-05-16 1900-01-01
DE1193044B (en) * 1963-08-05 1965-05-20 Bayer Ag Process for making phosphorylated urethanes
DE2512375A1 (en) * 1975-03-21 1976-09-30 Bayer Ag 1-HYDROXY-2,2,2-TRICHLORAETHANE THIONOPHOSPHONIC ACID DIAL KYLESTER, METHOD FOR THEIR PRODUCTION AND THEIR USE AS INSECTICIDES
US4950658A (en) * 1988-12-06 1990-08-21 Board Of Trustees Of Southern Illinois Univ. Method of medical treatment of Alzheimer's disease

Also Published As

Publication number Publication date
WO1997039756A1 (en) 1997-10-30
ZA973538B (en) 1997-11-18
JP2000510455A (en) 2000-08-15
CA2252567A1 (en) 1997-10-30
BR9709300A (en) 1999-08-10
CZ343498A3 (en) 1999-02-17
NO984964D0 (en) 1998-10-23
IL126698A0 (en) 1999-08-17
EP0896540A1 (en) 1999-02-17
AU2462397A (en) 1997-11-12
NO984964L (en) 1998-12-22
AR006870A1 (en) 1999-09-29
SK146398A3 (en) 1999-06-11
ID16678A (en) 1997-10-30
KR20000010611A (en) 2000-02-25
TR199802137T2 (en) 1999-02-22
DE19616471A1 (en) 1997-10-30
HUP9903366A3 (en) 2000-08-28
PL333464A1 (en) 1999-12-20
HUP9903366A2 (en) 2000-07-28

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