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BG106491A - Хиназолинови съединения и фармацевтични състави които ги съдържат - Google Patents

Хиназолинови съединения и фармацевтични състави които ги съдържат Download PDF

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Publication number
BG106491A
BG106491A BG106491A BG10649102A BG106491A BG 106491 A BG106491 A BG 106491A BG 106491 A BG106491 A BG 106491A BG 10649102 A BG10649102 A BG 10649102A BG 106491 A BG106491 A BG 106491A
Authority
BG
Bulgaria
Prior art keywords
alkyl
group
hydrogen
optionally substituted
independently
Prior art date
Application number
BG106491A
Other languages
Bulgarian (bg)
English (en)
Inventor
Andrew Mortlock
Nicholas KEEN
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9922156.6A external-priority patent/GB9922156D0/en
Priority claimed from GBGB9922152.5A external-priority patent/GB9922152D0/en
Priority claimed from GBGB9922159.0A external-priority patent/GB9922159D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BG106491A publication Critical patent/BG106491A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BG106491A 1999-09-21 2002-03-07 Хиназолинови съединения и фармацевтични състави които ги съдържат BG106491A (bg)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9922156.6A GB9922156D0 (en) 1999-09-21 1999-09-21 Chemical compounds
GBGB9922152.5A GB9922152D0 (en) 1999-09-21 1999-09-21 Chemical compounds
GBGB9922159.0A GB9922159D0 (en) 1999-09-21 1999-09-21 Chemical compounds
PCT/GB2000/003556 WO2001021594A1 (en) 1999-09-21 2000-09-18 Quinazoline compounds and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
BG106491A true BG106491A (bg) 2002-12-29

Family

ID=27269803

Family Applications (1)

Application Number Title Priority Date Filing Date
BG106491A BG106491A (bg) 1999-09-21 2002-03-07 Хиназолинови съединения и фармацевтични състави които ги съдържат

Country Status (20)

Country Link
US (1) US7081461B1 (no)
EP (1) EP1218356A1 (no)
JP (1) JP2003509497A (no)
KR (1) KR20020032608A (no)
CN (1) CN1391561A (no)
AU (1) AU763242B2 (no)
BG (1) BG106491A (no)
BR (1) BR0014133A (no)
CA (1) CA2384282A1 (no)
CZ (1) CZ20021010A3 (no)
EE (1) EE200200149A (no)
HK (1) HK1046688A1 (no)
HU (1) HUP0204413A3 (no)
IL (1) IL148489A0 (no)
IS (1) IS6304A (no)
NO (1) NO20021401L (no)
PL (1) PL354923A1 (no)
SK (1) SK3832002A3 (no)
TR (1) TR200200749T2 (no)
WO (1) WO2001021594A1 (no)

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UA73993C2 (uk) 2000-06-06 2005-10-17 Астразенека Аб Хіназолінові похідні для лікування пухлин та фармацевтична композиція
EP1313727A1 (en) 2000-08-21 2003-05-28 AstraZeneca AB Quinazoline derivatives
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JP2004511480A (ja) 2000-10-13 2004-04-15 アストラゼネカ　アクチボラグ キナゾリン誘導体
JP4564713B2 (ja) 2000-11-01 2010-10-20 ミレニアム・ファーマシューティカルズ・インコーポレイテッド 窒素性複素環式化合物、ならびに窒素性複素環式化合物およびその中間体を作製するための方法
US7141577B2 (en) 2001-04-19 2006-11-28 Astrazeneca Ab Quinazoline derivatives
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US7495104B2 (en) 2001-10-17 2009-02-24 Kirin Beer Kabushiki Kaisha Quinoline or quinazoline derivatives inhibiting auto-phosphorylation of fibroblast growth factor receptors
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US6924285B2 (en) * 2002-03-30 2005-08-02 Boehringer Ingelheim Pharma Gmbh & Co. Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
ATE429230T1 (de) 2002-07-09 2009-05-15 Astrazeneca Ab Chinazoline derivative und ihre anwendung in der krebsbehandlung
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US7329664B2 (en) 2003-07-16 2008-02-12 Neurogen Corporation Substituted (7-pyridyl-4-phenylamino-quinazolin-2-yl)-methanol analogues
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US20070054916A1 (en) * 2004-10-01 2007-03-08 Amgen Inc. Aryl nitrogen-containing bicyclic compounds and methods of use
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EP1833482A4 (en) 2005-01-03 2011-02-16 Myriad Genetics Inc COMPOUNDS AND ITS THERAPEUTIC USE
US8258145B2 (en) 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer
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US7732613B2 (en) 2005-09-14 2010-06-08 Bristol-Myers Squibb Company Met kinase inhibitors
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Also Published As

Publication number Publication date
IS6304A (is) 2002-03-18
AU7432500A (en) 2001-04-24
NO20021401L (no) 2002-05-21
BR0014133A (pt) 2002-06-11
HK1046688A1 (zh) 2003-01-24
KR20020032608A (ko) 2002-05-03
CA2384282A1 (en) 2001-03-29
PL354923A1 (en) 2004-03-22
CZ20021010A3 (cs) 2002-06-12
JP2003509497A (ja) 2003-03-11
WO2001021594A1 (en) 2001-03-29
AU763242B2 (en) 2003-07-17
US7081461B1 (en) 2006-07-25
NO20021401D0 (no) 2002-03-20
IL148489A0 (en) 2002-09-12
CN1391561A (zh) 2003-01-15
HUP0204413A2 (en) 2003-05-28
EE200200149A (et) 2003-04-15
SK3832002A3 (en) 2002-11-06
HUP0204413A3 (en) 2003-07-28
EP1218356A1 (en) 2002-07-03
TR200200749T2 (tr) 2002-06-21

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