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BE869485A - NEW DERIVATIVES OF DOXORUBICIN, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM - Google Patents

NEW DERIVATIVES OF DOXORUBICIN, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM

Info

Publication number
BE869485A
BE869485A BE189673A BE189673A BE869485A BE 869485 A BE869485 A BE 869485A BE 189673 A BE189673 A BE 189673A BE 189673 A BE189673 A BE 189673A BE 869485 A BE869485 A BE 869485A
Authority
BE
Belgium
Prior art keywords
doxorubicin
preparation
compositions containing
new derivatives
derivatives
Prior art date
Application number
BE189673A
Other languages
French (fr)
Original Assignee
Inst Internat De Pathologie Ce
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Internat De Pathologie Ce filed Critical Inst Internat De Pathologie Ce
Priority to BE189673A priority Critical patent/BE869485A/en
Publication of BE869485A publication Critical patent/BE869485A/en
Priority to DE2930637A priority patent/DE2930637C2/en
Priority to SE7906464A priority patent/SE446537B/en
Priority to CH704279A priority patent/CH641960A5/en
Priority to IT49944/79A priority patent/IT1117790B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
BE189673A 1978-08-03 1978-08-03 NEW DERIVATIVES OF DOXORUBICIN, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM BE869485A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
BE189673A BE869485A (en) 1978-08-03 1978-08-03 NEW DERIVATIVES OF DOXORUBICIN, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM
DE2930637A DE2930637C2 (en) 1978-08-03 1979-07-27 N- (L-Leucyl) -doxorubicin, process for its production and pharmaceutical preparations containing it
SE7906464A SE446537B (en) 1978-08-03 1979-07-30 DOXORUBICIN DERIVATIVES, SET TO PREPARE THEM AND PHARMACEUTICAL COMPOSITION CONTAINING SUCH DERIVATIVES
CH704279A CH641960A5 (en) 1978-08-03 1979-07-31 Doxorubicin derivatives, their preparation and compositions containing them
IT49944/79A IT1117790B (en) 1978-08-03 1979-08-02 DOSSORUBICIN DERIVATIVES EQUIPPED WITH ANTI-TUMOR ACTIVITY PROCEDURE FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE189673A BE869485A (en) 1978-08-03 1978-08-03 NEW DERIVATIVES OF DOXORUBICIN, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM
BE869485 1978-08-03

Publications (1)

Publication Number Publication Date
BE869485A true BE869485A (en) 1978-12-01

Family

ID=25650923

Family Applications (1)

Application Number Title Priority Date Filing Date
BE189673A BE869485A (en) 1978-08-03 1978-08-03 NEW DERIVATIVES OF DOXORUBICIN, THEIR PREPARATION AND THE COMPOSITIONS CONTAINING THEM

Country Status (1)

Country Link
BE (1) BE869485A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0294294A3 (en) * 1987-06-05 1990-05-30 Cytogen Corporation Amine derivatives of anthracycline antibiotics and antibody conjugates thereof
FR2678274A1 (en) * 1991-06-25 1992-12-31 Medgenix Group Sa N-Leucylepirubicin, application as antitumour medicinal product and process for preparing it
WO1996005863A1 (en) * 1994-08-19 1996-02-29 La Region Wallonne Compounds, pharmaceutical composition and diagnostic device comprising same and their use
BE1008581A3 (en) * 1994-08-19 1996-06-04 Wallone Region Pro-drugs, pharmaceutical formulation comprising said pro-drugs and usethereof
US7115573B2 (en) 2000-06-14 2006-10-03 Medarex, Inc. Prodrug compounds with an isoleucine
US7425541B2 (en) 1998-12-11 2008-09-16 Medarex, Inc. Enzyme-cleavable prodrug compounds

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0294294A3 (en) * 1987-06-05 1990-05-30 Cytogen Corporation Amine derivatives of anthracycline antibiotics and antibody conjugates thereof
FR2678274A1 (en) * 1991-06-25 1992-12-31 Medgenix Group Sa N-Leucylepirubicin, application as antitumour medicinal product and process for preparing it
US7037898B2 (en) 1994-08-19 2006-05-02 Laregion Wallone Tumor-activated prodrug compounds and treatment
BE1008581A3 (en) * 1994-08-19 1996-06-04 Wallone Region Pro-drugs, pharmaceutical formulation comprising said pro-drugs and usethereof
US5962216A (en) * 1994-08-19 1999-10-05 La Region Wallonne Tumor-activated prodrug compounds and treatment
US6342480B1 (en) 1994-08-19 2002-01-29 La Region Wallone Tumor-activated prodrug compounds and treatment
WO1996005863A1 (en) * 1994-08-19 1996-02-29 La Region Wallonne Compounds, pharmaceutical composition and diagnostic device comprising same and their use
US7390629B2 (en) 1994-08-19 2008-06-24 La Region Wallonne Tumor-activated prodrug compounds and treatment
US7951772B2 (en) 1994-08-19 2011-05-31 La Region Wallonne Tumor-activated prodrug compounds and treatment
US7425541B2 (en) 1998-12-11 2008-09-16 Medarex, Inc. Enzyme-cleavable prodrug compounds
US8034787B2 (en) 1998-12-11 2011-10-11 Medarex, Inc. Enzyme-cleavable prodrug compounds
US7115573B2 (en) 2000-06-14 2006-10-03 Medarex, Inc. Prodrug compounds with an isoleucine
US7329507B2 (en) 2000-06-14 2008-02-12 Medarex, Inc. Prodrug compounds with isoleucine
US7696313B2 (en) 2000-06-14 2010-04-13 Medarex, Inc. Prodrug compounds with isoleucine

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: INSTITUT INTERNATIONAL DE PATHOLOGIE CELLULAIRE E

Effective date: 19950831